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Patent # Description
US-9,757,405 Compositions comprising rutin useful for the treatment of tumors resistant to chemotherapy
Use of rutin for increasing the effectiveness of chemotherapeutic treatments used in human and veterinary medicine for the treatment of tumors is described, in...
US-9,757,404 Combination comprising an omega-3 fatty acid composition and an SGLT2 inhibitor
A method for treating NAFLD and/or NASH and suitable compositions for carrying out the method are claimed.
US-9,757,403 Glycan therapeutics and related methods thereof
Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics,...
US-9,757,402 Method for measuring cell-to-cell transmission of .alpha.-synuclein aggregates using bimolecular fluorescence...
The present disclosure relates to dual-cell model and Caenorhabditis elegans model systems for measuring neuron-to-neuron transmission of protein aggregates,...
US-9,757,401 Method for relieving neurogenic pain
An inventive composition including an amount of sugar or sugar alcohol, an amount of alkalizing agent, and an amount of vehicle; whereby the inventive...
US-9,757,400 Peptidomimetic inhibitors of post-proline cleaving enzymes
Disclosed are inhibitors of post-proline cleavage enzymes, such as inhibitors of dipeptidyl peptidase IV, as well as pharmaceutical compositions thereof, and...
US-9,757,399 Butyrylcholinesterase inhibitors
Butyrylcholinesterase inhibitors, their formulation, and their use primarily in the treatment of neurodegenerative diseases. These inhibitors generally are...
US-9,757,398 Prevention and treatment of alzheimer's disease by amyloid beta peptide and sphin-gosine-1-phosphate
The invention provides compositions and methods for treatment of Alzheimer's disease. Such methods entail administering agents that induce a beneficial immune...
US-9,757,397 Methods of manufacturing topical compositions and apparatus for the same
Provided according to some embodiments of the invention are methods of manufacturing a pharmaceutical composition. In some embodiments, such methods include...
US-9,757,396 Method for treating recurring skin and mucous membrane diseases caused by HSV-1 and HSV-2
The invention relates to medicine and specifically to methods for treating recurring forms of diseases related to the family of herpes viruses. A method for...
US-9,757,395 Dry powder inhaler and methods of use
Methods for reducing the risk of a thromboembolic event, and a related drug delivery system are provided. In some embodiments, a dose of acetylsalicylic acid...
US-9,757,394 Spironolactone aqueous formulations
Disclosed herein is a pharmaceutical composition, comprising: (a) spironolactone; (b) a xanthan gum; (c) an anti-foaming agent; (d) a preservative; (f) a...
US-9,757,393 Derivatives of ergostatrien-3-.beta.-ol from antrodia camphorata and antiglycemic, antihyperlipidemic and...
The present invention provides a method for treating diabetes, hyperlipidemia or hepatic total lipids by using ergostatrien-3.beta.-ol and its derivatives, as...
US-9,757,392 Pharmaceutical composition and extract of Poria for enhancing uptake of nutrients
The present invention discloses a novel use of a lanostane having the following formula (I) in enhancing uptake of nutrients: ##STR00001## wherein R.sub.1 is...
US-9,757,391 Neuroactive steroids and their use to facilitate neuroprotection
The present disclosure teaches generally neuroprotection and in particular the use of non-hormonal neuroactive steroids to ameliorate inflammation of the...
US-9,757,390 High-strength testosterone undecanoate compositions
The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The...
US-9,757,389 Bioavailable solid state (17-.beta.)-hydroxy-4-androsten-3-one esters
Disclosed are bioavailable solid state (17-.beta.)-Hydroxy-4-Androsten-3-one esters suitable for pharmaceutical uses and administration to mammals in need of ...
US-9,757,388 Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels
The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the...
US-9,757,387 Antimicrobial compositions and methods of making the same
The present disclosure comprises antimicrobial compositions and devices comprising silver compounds that resist heat and light discoloration. In one aspect, the...
US-9,757,386 Targeting corroles for tumor toxicity and MRI
Disclosed herein are compositions comprising a targeted corrole nanoparticle; and an acceptable excipient. Also disclosed are compositions comprising a targeted...
US-9,757,385 Method of treating leukemia using pharmaceutical formulation containing thienotriazolodiazepine compounds
A method of treating leukemia in a mammal by administering a solid dispersion comprising an amorphous thienotriazolodiazepine compound of the Formula (1)...
US-9,757,384 Methods for treating subjects with Prader-Willi syndrome or Smith-Magenis syndrome
Provided are immediate or prolonged administration of certain potassium ATP (K.sub.ATP) channel openers, optionally in combination with growth hormone, to a...
US-9,757,383 Cyclohexylamine derivatives having .beta.2 adrenergic agonist and M3 muscarinic antagonist activities
The present invention relates to novel compounds having .beta.2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions...
US-9,757,382 Quinazolines and azaquinazolines as dual inhibitors of RAS/RAF/MEK/ERK and PI3K/AKT/PTEN/mTOR pathways
The present application provides novel quinazolines and azaquinazolines and pharmaceutically acceptable salts thereof. Also provided are methods for preparing...
US-9,757,381 Compounds, compositions and methods useful for cholesterol mobilization
The invention relates to classes of pharmaceutically-active heterocyclic compounds and pharmaceutically acceptable salts, and hydrates thereof, and compositions...
US-9,757,380 Methods for treating neoplasia with combination of chemotherapeutic agents and radiation
Methods for treating neoplasia with a chemotherapeutic agent and radiation are provided. Radiation therapies used in conduction with a compound described herein...
US-9,757,379 Inhibition of HIF-2.alpha. heterodimerization with HIF1.beta. (ARNT)
Provided is a method of inhibiting heterodimerization of HIF-2.alpha. to HIF1.beta. (ARNT) comprising binding certain small molecules to the HIF-2.alpha. PAS-B...
US-9,757,378 Methods to modulate acute myeloid leukemia stem/progenitor cell expansion and/or differentiation
Novel methods for modulating acute myeloid leukemia stem/progenitor cell expansion and/or differentiation are disclosed. These methods are based on the use of...
US-9,757,377 Solid preparation
The present invention provides a solid preparation excellent in disintegration property and preservation stability. The present invention relates to a solid...
US-9,757,376 Pharmaceutical compositions
A composition of an antitussive, a decongestant, or an antihistamine to treat upper respiratory and oral pharyngeal congestion and related symptoms in a patient.
US-9,757,375 Compounds that inhibit human DNA ligases and methods of treating cancer
Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into...
US-9,757,374 Aripiprazole compositions and methods for its transdermal delivery
The present invention discloses compositions of liquid and gel formulation containing aripiprazole in the form of a patch for transdermal delivery.
US-9,757,373 MetAP2 inhibitors and methods of treating obesity
The present invention relates to modified or polymer conjugated MetAP2 inhibitors. The present invention also relates to methods of preventing, inducing,...
US-9,757,372 Toll-like receptor 4 antagonists and use in autoimmune liver diseases
The present invention relates to new medical uses of morphinans such as naltrexone, nalmefene and their related derivatives. The present invention relates to...
US-9,757,371 Immediate release abuse-deterrent granulated dosage forms
Described are immediate release oral dosage forms that contain abuse-deterrent features. In particular, the disclosed dosage forms provide deterrence of abuse...
US-9,757,370 Opsin-binding ligands, compositions and methods of use
Compounds are disclosed that are useful for treating ophthalmic conditions caused by or related to production of toxic visual cycle products that accumulate in...
US-9,757,369 Heterocyclic GSK-3 allosteric modulators
The present invention relates to heterocyclic substituted quinoline derivatives as allosteric inhibitors of the glycogen synthase kinase-3 (GSK-3) enzyme....
US-9,757,368 Anti-inflammatory agents
Disclosed are methods of regulating interleukin-6 (IL-6) and/or vascular cell adhesion molecule-1 (VCAM-1) and methods of treating and/or preventing...
US-9,757,367 Calcium propane-2-sulfinate dihydrate
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsu- ...
US-9,757,366 Methods for the treatment of parkinson's disease psychosis using pimavanserin
Methods for the treatment of Parkinson's disease psychosis which comprise the administration of pimavanserin.
US-9,757,365 Tiotropium inhalation solution for nebulization
The present invention relates to a sterile pharmaceutical composition comprising tiotropium or a pharmaceutically acceptable salt thereof, for inhalation via...
US-9,757,364 Naphthyridine derivative compounds
The invention relates to new naphthyridine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of...
US-9,757,363 SNS-595 and methods of using the same
The present invention relates to SNS-595 and methods of treating cancer using the same.
US-9,757,362 Modified release compositions comprising tacrolimus
A modified release composition comprising tacrolimus releases less than 20% w/w of the active ingredient within 0.5 hours when subjected to an in vitro...
US-9,757,361 Treatment of psoriasis and of other skin disorders associated with inhibition of differentiation of epidermal...
This invention concerns the use of cyclopamine, a naturally occurring steroidal alkaloid known for over thirty years, for the treatment of psoriasis and...
US-9,757,360 Pharmaceutical composition comprising a ryanodine receptor antagonist for facilitating wound healing
The invention relates to the use of pharmaceutical compositions containing as the active agent a compound of formula I in the treatment of dermal wounds. The...
US-9,757,359 Synthetic triterpenoids and methods of use in the treatment of disease
The present invention concerns methods for treating and preventing renal/kidney disease, insulin resistance/diabetes, fatty liver disease, and/or endothelial...
US-9,757,358 Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and...
The invention refers to a combination comprising a sigma ligand of formula (I) and an opioid or opiate for use in the prevention and/or treatment of pain...
US-9,757,357 Photodynamic therapy or diagnostic agent, using infrared-spectrum light
It is intended to provide a therapeutic and/or diagnostic agent that can be used in photodynamic therapy (PDT) or photodynamic diagnosis (PDD) capable of...
US-9,757,356 Composition comprising bio compound for treating cardiovascular disease
A pharmaceutical composition and a method for preventing or treating a cardiovascular disease are provided. The pharmaceutical composition includes a BIO...
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