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Patent # Description
US-9,770,491 AAV-mediated gene therapy for RPGR X-linked retinal degeneration
Described herein are methods of preventing, arresting progression of or ameliorating vision loss and other conditions associated with retinitis pigmentosa and...
US-9,770,490 Oral delivery for hemoglobin based oxygen carriers
A process for making hemoglobin based oxygen carrier (HBOC) containing pharmaceutical composition suitable for oral delivery and the composition formed thereby...
US-9,770,489 Methods and products for nucleic acid production and delivery
The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods...
US-9,770,488 Human placental collagen compositions, and methods of making and using the same
The present invention provides compositions comprising human placental telopeptide collagen, methods of preparing the compositions, methods of their use and...
US-9,770,487 Combination therapy involving antibodies against claudin 18.2 for treatment of pancreatic adenocarcinoma
The present invention provides a combination therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, including...
US-9,770,486 Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists
Disclosed are novel methods for preventing or attenuating neuronal damage or stimulating neuronal repair, prior to or following central nervous system injury...
US-9,770,485 Methods for rescuing learning and/or memory deficits caused by alzheimer's disease by G-CSF
A method for treating a progressive neurodegenerative disorder with bone marrow stem cells and a G-CSF receptor agonist.
US-9,770,484 BPI and its congeners as radiation mitigators and radiation protectors
Described herein is a method of mitigating, in a subject (individual), tissue injury resulting from exposure to radiation (accidental/unintentional or...
US-9,770,483 BPI and its congeners as radiation mitigators and radiation protectors
Described herein is a method of mitigating, in a subject (individual), tissue injury resulting from exposure to radiation (accidental/unintentional or...
US-9,770,482 Targeting the EGFR-SGLT1 interaction for cancer therapy
A compound can destabilize an epidermal growth factor receptor (EGFR) protein and a sodium/glucose co-transporter 1 (SGLT 1) protein. In one embodiment, the...
US-9,770,481 Inhibitors of NOX1
The present invention relates to inhibitors of Nox1-dependent reactive oxygen species production and their use in the treatment of disorders associated with...
US-9,770,480 Producing a topical solution coposition
A process of providing a topical solution which includes a high level of resveratrol by using a low temperature mixing process. The low temperature mixing...
US-9,770,479 Extract of Rehmannia glutinasa Libosch for reducing blood sugar, reducing blood fat, treating leukemia, and...
The present invention relates to a Rehmannia glutinasa Libosch. extract for reducing blood glucose and lipid levels and treating hematologic diseases such as...
US-9,770,478 Method for inhibiting neuronal cell aggregation
The invention relates to a novel use of the Chinese herb Glycyrrhiza inflata in treatment of neurodegenerative disorders. Particularly, the invention relates to...
US-9,770,477 Natural antioxidant anti-influenza composition
The invention relates to a composition from the extract of Myrciaria dubia and Echinacea purpurea, which has a synergistic effect. The composition of the...
US-9,770,475 Compositions for the treatment of peripheral ulcers of various origins
The present invention relates to compositions containing a combination of a cell proliferation-stimulating agent with vasokinetic properties and an ...
US-9,770,474 Bacterial extracts cultured in thermal waters comprising anti-redness agents
Red blotches on the skin such as those associated with environmental stresses, or red blotches associated with a skin disorder, for example those occurring...
US-9,770,473 Treatment of immunosuppression-related disorders
Disclosed are methods of using blastomere-like stem cells to decrease a level of myeloid-derived suppressor cells (MDSCs). A method for decreasing a level of...
US-9,770,472 Organ jacket and methods of use
An organ jacket fabricated from human birth tissue comprising at least one cross-linked amniotic membrane, or at least one cross-linked chorionic membrane, or...
US-9,770,471 Conversion of somatic cells into functional spinal motor neurons, and methods and uses thereof
The present invention provides methods of transdifferentiation of somatic cells, for example, directly converting a somatic cell of a first cell type, e.g., a...
US-9,770,470 Closed system separation of adherent bone marrow stem cells for regenerative medicine applications
A method for isolating and processing bone marrow derived stem cells, including the steps of: (a) collecting a biological sample containing adherent bone marrow...
US-9,770,469 Methods of reprogramming renal cells
A method of reprogramming a differentiated renal cell towards a progenitor phenotype is disclosed. The method comprises up-regulating in the differentiated...
US-9,770,468 Use of whey permeate for the treatment of metabolic syndrome
The invention relates to the use of whey permeate, preferably sweet whey permeate and more preferably hydrolysed or partially-hydrolysed sweet whey permeate for...
US-9,770,467 Compositions and methods for cancer immunotherapy
The present invention provides a combination therapy which relies on a small molecule immune stimulator--cyclic-di-nucleotide (CDN)--that activates DCs via a...
US-9,770,466 Ophthalmic composition and methods of use
Described are stable topical formulations useful in the treatment of viral infection, demodex infection and bacterial infection of the eye, and methods of using...
US-9,770,465 Inherently radiopaque polymeric products for embolotherapy
Preferred embodiments relate to compositions of inherently radiopaque, biocompatible, bioresorbable polymeric particles and methods of using them for embolizing...
US-9,770,464 Methods of treating optic disorders
The present invention relates to methods for treating optic disorders or for reducing or alleviating the signs, symptoms, or pathological conditions related to...
US-9,770,463 Delivery of RNA to different cell types
RNA encoding an immunogen is co-delivered to non-immune cells at the site of delivery and also to immune cells which infiltrate the site of delivery. The...
US-9,770,462 Method of treating ovarian, tubal and peritoneal cancer
A method of treating ovarian, tubal and peritoneal cancer is revealed. It comprises administering an effective amount of a pharmaceutical composition (including...
US-9,770,461 Tailored glycopolymers as anticoagulant heparin mimetics
The present disclosure provides for methods and compositions comprising a series of synthetic glycopolymers. The disclosure also relates to a kit which is...
US-9,770,460 Non-digestible oligosaccharides for oral induction of tolerance against dietary proteins
Compositions and methods for providing infant nutrition with partially hydrolysed proteins and non-digestible oligosaccharides for use in induction of oral...
US-9,770,459 Substituted bicyclic compounds
Disclosed are compounds of Formulas (I), (II), (III), (IV), and (V): ##STR00001## and/or a salt thereof, wherein R.sub.1 is --OH or --OP(O)(OH).sub.2, and...
US-9,770,458 Anti-cancer agent containing a diacylphosphatidylethanolamine as an active ingredient
The present invention provides an anti-cancer agent, a cancer cell death inducing agent, a protein phosphatase 2A activation enhancing agent, a protein tyrosine...
US-9,770,457 Neridronic acid for treating bone marrow lesion
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions such as...
US-9,770,456 Compositions comprising acidic extracts of mastic gum
The invention relates to compositions and formulations comprising isolated acidic fraction of mastic gum and uses thereof for treating impaired neurological...
US-9,770,455 Administration of an anti-obesity compound to individuals with renal impairment
The present disclosure relates to methods for weight management in an individual in need thereof by determining the level of renal sufficiency of the individual...
US-9,770,454 IGF-1R signaling pathway inhibitors useful in the treatment of neurodegenerative diseases
The present invention provides compounds acting as Insulin/IGF signaling modulators useful in the treatment of neurodegenerative diseases and disorders. The...
US-9,770,453 Combination of brimonidine and timolol for topical ophthalmic use
Disclosed are pharmaceutical compositions comprising brimonidine and timolol for topical ophthalmic delivery and a method of treatment comprising administering...
US-9,770,452 Quinoxaline derivatives as GPR6 modulators
The present invention provides compounds of Formula (I): ##STR00001## that are GPR6 modulators and are therefore useful for the treatment of diseases treatable...
US-9,770,451 Composition including ATM inhibitor for reducing cellular senescence and use of the composition
A composition including an ataxia telangiectasia mutated (ATM) inhibitor for reducing cellular senescence, a method of reducing cellular senescence in a mammal,...
US-9,770,450 4-OXO-3,4-dihydro-1,2,3-benzotriazine as modulators of GPR139
The present invention provides a method for treating a disease, disorder or condition associated with GPR139 using compounds of formula 1: ##STR00001## which...
US-9,770,449 Parasiticidal compositions comprising multiple active agents, methods and uses thereof
This invention relates to compositions for combating ectoparasites and endoparasites in animals, comprising at least one 1-arylpyrazole, at least one...
US-9,770,448 Compositions and methods for treatment of Bowen's disease and related diseases
Compositions and methods for the treatment of Bowen's disease, an orphan disease, are described. In addition, compositions and methods for the treatment of...
US-9,770,447 Ophthalmic composition
Provided herein is an ophthalmic composition. In some embodiments, the ophthalmic composition includes a low concentration of an ophthalmic agent for treatment...
US-9,770,446 Piperidine urea derivatives
Compounds of the formula I ##STR00001## in which R.sup.1-R.sup.3 have the meanings indicated in Claim 1, are inhibitors of Tankyrase, and can be employed,...
US-9,770,445 Sulfoximine substituted 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives and their use as CDK9 kinase...
The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and...
US-9,770,444 Compositions and methods for modulating circadian synchronization
The present invention relates to a modulator of glucocorticoid biosynthesis, degradation and/or receptor activation for use in preventing or treating symptoms...
US-9,770,443 Aerosol pirfenidone and pyridone analog compounds and uses thereof
Disclosed herein are formulations of pirfenidone or pyridone analog compounds for aerosolization and use of such formulations for aerosol administration of...
US-9,770,442 Self-assembling amphiphilic polymers as anti-cancer agents
The invention provides amphiphilic biocompatible copolymers which have a hydrophilic backbone and pendant hydrophobic groups. The polymers form nanoscale...
US-9,770,441 Crystalline solid forms of 6-carboxy-2-(3,5-dichlorophenyl)-benzoxazole
The present invention relates to solid forms of 6-carboxy-2-(3,5-dichlorophenyl)-benzoxazole and to methods for their preparation. The invention is also...
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