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Patent # Description
US-9,862,992 Surface of substrate onto which non-specific adsorption is restrained
A substrate surface on which either a substance to detect analyte or an analyte per se is immobilized, which surface is formed by a treatment of substrate...
US-9,862,991 Gene synthesis process, gene chip and kit
Provided is a chip process of gene synthesis, and the process comprises incorporating the whole procedure, which comprises amplifying oligonucleotides and...
US-9,862,990 Signal amplification
The present invention relates to compositions and methods for the use of enzymes composed of nucleic acid and/or protein enzymes to generate and amplify a...
US-9,862,989 Nucleic acid probe, method for designing nucleic acid probe, and method for detecting target sequence
The present invention provides a nucleic acid probe that can achieve high detection sensitivity and high specificity in mutation detection, mismatch detection,...
US-9,862,988 Methods and kits for breaking emulsions
The disclosure relates generally to methods, kits and systems for extracting biomolecules from a water-in-oil emulsion, including breaking a water-in-oil...
US-9,862,987 Label free molecular detection methods, systems and devices
Methods, systems, and devices are disclosed for capturing, concentrating, isolating, and detecting molecules. In one aspect, a molecular probe device includes a...
US-9,862,986 Muteins of the pyrroline-5-carboxylate reductase 1
The invention relates to muteins of the pyrroline-5-carboxylate reductase 1 (PYCR1), to nucleic acid molecules comprising a nucleotide sequence encoding such...
US-9,862,985 Identification and susceptibility of microorganisms by species and strain
Devices, systems, and methods for strain-specific identification and assessment of susceptibility of microorganisms based on the response of sensors in a...
US-9,862,984 Single-molecule platform for drug discovery: methods and apparatuses for drug discovery, including discovery of...
The present application discloses methods and apparatuses for single molecule drug screening, discovery and validation. These methods and apparatuses allow a...
US-9,862,983 Recombinase-based amplification with substitute nucleotides
This invention covers methods for isothermal amplification of DNA, based on the unexpected discovery that primers having, at some positions, adenine substituted...
US-9,862,982 Methods of hydrolyzing a cellulose using halophilic, thermostable and ionic liquids tolerant cellulases
The present invention provides for an isolated or recombinant polypeptide comprising an amino acid sequence having at least 70% identity with the amino acid...
US-9,862,981 Thermophilic acetylxylan esterase genes and enzymes from alicyclobacillus acidocaldarius and related organisms...
A genetically modified organism comprising at least one nucleic acid sequence and/or at least one recombinant nucleic acid isolated from Alicyclobacillus...
US-9,862,980 Process for production of soluble sugars from biomass
The present invention provides a process for enzyme mediated hydrolysis of biomass for production of soluble sugars, wherein the said process comprises of...
US-9,862,979 Biosynthesis of opiate alkaloids
The disclosure relates to a nucleic acid molecule isolated from a Papaver somniferum cultivar that produces the opiate alkaloid noscapine which comprises 10...
US-9,862,978 Method for preparing (2RS)-amino-(3S)-hydroxy-butyric acid and its derivatives
The present invention relates to a method for easily preparing (2RS)-amino-(3S)-hydroxy-butyric acid, which is a chiral amino acid, in a high yield and a high...
US-9,862,977 Engineered microbes and methods for microbial oil production
Some aspects of this invention provide engineered microbes for oil production. Methods for microbe engineering and for use of engineered microbes are also...
US-9,862,976 Fermentive production of four carbon alcohols
Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth...
US-9,862,975 Compositions and methods for increased ethanol production from biomass
The present application discloses the identification of the novel K. marxianus xylose transporter genes KHT105 and RAG4, as well as the identification of a...
US-9,862,974 Cyanobacterium sp. host cell and vector for production of chemical compounds in cyanobacterial cultures
A genetically enhanced cyanobacterial host cell, Cyanobacterium sp. ABICyanoI, is disclosed. The enhanced Cyanobacterium sp. ABICyanoI produces a compound or...
US-9,862,973 Methods for biosynthesis of isoprene
This document describes biochemical pathways for producing isoprene by forming two vinyl groups in a central precursor produced from isobutyryl-CoA,...
US-9,862,972 CMV glycoproteins and recombinant vectors
Disclosed herein are recombinant CMV vectors which may comprise a heterologous antigen that can repeatedly infect an organism while inducing a CD8+ T cell...
US-9,862,971 Pseudotyping of retroviral vectors, methods for production and use thereof for targeted gene transfer and high...
The invention relates to the pseudotyping of retroviral vectors with heterologous envelope proteins derived from the Paramyxoviridae family, genus...
US-9,862,970 Retinal on bipolar cells-specific artificial promoter
An isolated nucleic acid molecule comprising the nucleic acid sequence of SEQ ID NO:1, or a nucleic acid sequence of at least 1000 bp having at least 70%...
US-9,862,969 Promoter derived from human gene
The present invention relates to a transfected mammalian host cell whose ability to secrete a foreign protein has been enhanced by using a foreign gene...
US-9,862,968 NF-.kappa.B signaling pathway-manipulated dendritic cells
The invention relates to dendritic cells, the NF.kappa.B signaling pathway of which has been manipulated by RNA transfection, to the manufacture thereof and to...
US-9,862,967 AXMI281 toxin gene and methods for its use
Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding...
US-9,862,966 Methods and compositions for gray leaf spot resistance in corn
The present invention relates to the field of plant breeding. More specifically, the present invention includes a method of using haploid plants for genetic...
US-9,862,965 AXMI205 variant proteins and methods of use
Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding...
US-9,862,964 Transgenic plants with enhanced growth characteristics
The invention relates to transgenic plants exhibiting dramatically enhanced growth rates, greater seed and fruit/pod yields, earlier and more productive...
US-9,862,963 Gene for increasing plant weight and method for using the same
A gene having novel functions is searched for, by which plant weight (that is, biomass level) can be increased and by which substance productivity can be...
US-9,862,962 Identification and use of tomato genes controlling salt/drought tolerance and fruit sweetness
The present invention provides the identification and use of EGTom1 and/or EGTom2, homologs of EGTom1 and/or EGTom2, orthologs of EGTom1 and/or EGTom2, paralogs...
US-9,862,961 Biomass production increasing gene and transgenic plant using same
The present disclosure relates to, inter alia, a gene for increasing biomass production isolated from Arabidopsis thaliana, and a method for producing a...
US-9,862,960 Method for the transient expression of nucleic acids in plants
Compositions and methods for transiently expressing proteins in a plant are provided. The compositions comprise plants, seeds, plant tissues, and plant parts...
US-9,862,959 Transgenic plants with enhanced agronomic traits
This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to...
US-9,862,958 Nucleotide sequence and a process thereof
The present disclosure relates to a process of identification and isolation of sorbitol dehydrogenase promoter from Pichia pastoris. Further, the present...
US-9,862,957 Specific alleles important for ethanol tolerance
The present disclosure relates to the identification of a QTL associated with high ethanol tolerance in Saccharomyces spp. More specifically, it relates to...
US-9,862,956 Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
The invention is generally directed to modified filamentous fungal host cells comprising one or more nucleic acids encoding one or more polypeptides under the...
US-9,862,955 Plant endophytic bacteria Bacillus oryzicola isolated from rice rizhosphere, and development of agent for...
A strain has a microorganism fertilizer efficacy and can be used as a biopesticide, by isolating multi-functional plant endophytic bacteria, which can widely...
US-9,862,954 DNA vector production system
A vector production system is provided. The system comprises recombinant cells designed to encode at least a first recombinase under the control of an inducible...
US-9,862,953 Use of aptamers in therapy and/or diagnosis of autoimmune diseases
The present invention is directed to an aptamer comprising or consisting of the nucleic acid sequence of SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 and/or a...
US-9,862,952 Oligonucleotide compounds for treatment of preeclampsia and other angiogenic disorders
This disclosure relates to novel targets for angiogenic disorders. Novel oligonucleotides are also provided. Methods of using the novel oligonucleotides for the...
US-9,862,951 RNA interference-based therapeutic against anthrax
The present invention includes siRNAs and antibodies that block the interaction between TEM8 and/or CMG2 cell surface proteins and anthrax toxin and methods of...
US-9,862,950 Targeting microRNAs for metabolic disorders
Described herein are compounds comprising modified oligonucleotides that are complementary to miR-103 and/or miR-107 and methods of treating diseases and...
US-9,862,949 Method for the inhibition of angiogenesis
The invention relates to a method for influencing the miR-92 expression in a cell, comprising the following steps: (a) providing a cell; and (b1) reducing the...
US-9,862,948 Microrna inhibition for the treatment of inflammation and myeloproliferative disorders
The present disclosure relates to the finding that microRNA-155 plays a role in inflammation, hematopoiesis and myeloproliferation, and that dysregulation of...
US-9,862,946 Peptide oligonucleotide conjugates
Oligonucleotide analogs conjugated to carrier peptides are provided. The disclosed compounds are useful for the treatment of various diseases, for example...
US-9,862,945 Recombinant adeno-associated virus delivery of exon 2-targeted U7SNRNA polynucleotide constructs
The present invention relates to recombinant adeno-associated virus (rAAV) delivery of polynucleotides for treating Duchenne Muscular Dystrophy resulting from...
US-9,862,944 Antisense oligonucleotides for treatment of cancer stem cells
The invention provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their...
US-9,862,943 Long noncoding RNAs and cell reprogramming and differentiation
Long noncoding RNAs (lncRNAs) are identified that enhance pluripotency reprogramming of somatic cells as well as differentiation of pluripotent cells. Induced...
US-9,862,942 In vitro membrane protein molecular evolutionary engineering technique
The objective of the present invention is to improve the efficiency of screening/selection of a membrane protein in molecular evolutionary engineering (for...
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