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Patent # Description
US-9,889,166 Treating low production of mucus in the gastrointestinal tract with S. thermophilus
A composition for a medical device is described. The composition comprises a specific mucoadherent gelling complex composed of EPS, exopolysaccharides of...
US-9,889,165 Compositions and methods for treatment of skin disorders
Described herein are compositions and methods of treatment for acne and other skin disorders involving the use of probiotics. In certain aspects, microbes...
US-9,889,164 Bacteria engineered to treat a disease or disorder
Genetically programmed microorganisms, such as bacteria, pharmaceutical compositions thereof, and methods of modulating and treating a disease and/or disorder...
US-9,889,163 Bioeffective krill oil compositions
Krill oil compositions are disclosed as having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill...
US-9,889,162 Prophylactic use for prevention of infections
The present invention concerns the field of nutritional compositions and concerns a nutritional composition, especially an infant formula containing whey...
US-9,889,161 Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene
Disclosed herein is a genetically-modified cell comprising in its genome a modified human T cell receptor alpha constant region gene, wherein the cell has...
US-9,889,160 Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene
Disclosed herein is a genetically-modified cell comprising in its genome a modified human T cell receptor alpha constant region gene, wherein the cell has...
US-9,889,159 Peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-9,889,158 Pharmaceutical composition for the preparation of infusion solutions of antimicrobial preparations, its...
The proposed compositions and methods for preparation thereof relate to pharmacology, medicine, veterinary science and pharmaceutical industry. The compositions...
US-9,889,157 Phosphate-binding magnesium salts and uses thereof
The present invention provides, among other things, compositions and methods suitable for the treatment of hyperphosphatemia based on phosphate-binding...
US-9,889,156 Method for treating noise-induced hearing loss (NIHL)
A method for treating noise-induced hearing loss (NIHL) includes the step administering a composition to the mammal, wherein the composition consists...
US-9,889,155 Enhancer of anti-tumor effect of anti-cancer agent
An object of the present invention is to provide an agent that potentiates the antitumor effect of an anticancer agent by allowing efficient accumulation of the...
US-9,889,154 Hemostatic compositions, devices, and methods
Compositions that include a clay such as kaolin dispersed in a liquid such as water may be useful for promoting the clotting of blood. The compositions may be...
US-9,889,153 Highly stable electrolytic water with reduced NMR half line width
Electrolytic acid or alkaline water having a NMR half line width using 170 of from about 45 to less than 51 Hz, and an oxide reduction potential of from -1000...
US-9,889,152 Multiple PPI dosage form
Herein provided are dosage forms (variously referred to as "formulations") comprising a PPI that is released from the dosage form as a first and a second dose....
US-9,889,151 Silicate containing compositions and methods of treatment
The present invention relates to compositions comprising a silicate and methods of use thereof. In particular, the compositions of the present invention are...
US-9,889,150 Agents for the prevention and/or treatment of central nervous system damage
The present invention relates to the use of agents (including heparin derivatives) for the prevention and/or treatment of CNS damage.
US-9,889,149 Preparation for use of aspartate for regulating glucose levels in blood
The invention relates to the use of specific protein and/or peptide fractions having a high aspartate content for regulating plasma glucose concentrations and...
US-9,889,148 Use of pimobendan for the reduction of heart size in mammals suffering from heart failure
A phosphodiesterase type III (PDE III) inhibitor or Ca.sup.2+-sensitizing agent or a pharmaceutically acceptable derivative thereof is provided for the...
US-9,889,147 Analogues of etoposide for the treatment of tumours
Compounds for treatment of a patient having a tumor that is metastatic and/or that reduces an organ function, wherein the compounds are of the general formula: ...
US-9,889,146 Benzoxaborole compounds and uses thereof
Norvaline and/or other amino acids that are capable of being acylated onto tRNA.sup.Leu by LeuRS, in combination with substituted benzoxaboroles, such as a...
US-9,889,145 Methods to treat infections
Methods to treat infectious diseases are disclosed herein. Some embodiments of the invention include administration of one or more COX inhibitors (e.g., COX-1...
US-9,889,144 Abiraterone acetate formulation and methods of use
Pharmaceutical compositions, including unit dosage forms, comprising abiraterone acetate and methods for producing and using such compositions are described.
US-9,889,143 C17-heteroaryl derivatives of oleanolic acid and methods of use thereof
Disclosed herein are novel C17-heteroaryl derivatives of oleanolic acid, including those of the formula: ##STR00001## wherein the variables are defined...
US-9,889,142 Prostamide-containing intraocular implant
Prostamide-containing biodegradable intraocular implants, prostamide compounds, prostamide-containing pharmaceutical compositions, and methods for making and...
US-9,889,141 Combined inhibition of the vitamin D receptor and poly(ADP) ribose polymerase (PARP) in the treatment of cancer
Methods for treating tumors comprise contacting tumor cells expressing the vitamin D receptor with a vitamin D receptor ligand that inhibits homologous...
US-9,889,140 3-(1H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof
Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole...
US-9,889,139 Method of treating inflammatory bowel disease comprising administering a pharmaceutical composition comprising...
Provided is a method of treating inflammatory bowel disease comprising administering a pharmaceutical composition comprising a 6-aminopyridin-3-ol compound or a...
US-9,889,138 Method for treating cancer
The present invention provides a method for treating or alleviating a symptom of a disorder, e.g., immune evasion, cancer-cell induced immune dysfunction,...
US-9,889,137 Therapeutically active compounds and their methods of use
Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic...
US-9,889,136 Tetrahydropyridopyrimidine compound or salt thereof
A method for inhibiting androgen activity, including administering an effective amount of a tetrahydropyridopyrimidine compound of formula (I) or a...
US-9,889,135 Companion diagnostic for CDK4 inhibitors
The present invention relates to the use of one or more biomarkers to evaluate the likelihood that a CDK4 inhibitor would produce an anti-cancer effect in a...
US-9,889,134 Polymorphs of ARRY-380, a selective HER 2 inhibitor and pharmaceutical compositions containing them
Polymorphs of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dim- ethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine are provided...
US-9,889,133 Formulations of 5-fluorocytosine and uses thereof
The disclosure provides an extended release formulation of 5-fluorocytosine. In another aspect, a method of treating a fungal disease is provided. The method...
US-9,889,132 Pharmaceutical compositions for the treatment of psoriasis
Pharmaceutical compositions for topical administration for the treatment of psoriasis are described, containing as active ingredient therapeutically effective...
US-9,889,131 Cadherin-11 inhibitors and methods of use thereof
Cadherin-11 inhibitors and methods for the prevention and treatment of cadherin-11 related diseases are described herein. Cadherin-11 related diseases include...
US-9,889,130 Substituted 3-benzofuranyl-indol-2-one-3-acetamididopiperazine derivatives, preparation thereof, and...
The invention relates to disubstituted 3-benzofuranyl-indol-2-one-3-acetamidopiperazine derivatives of the general formula (I) where R1, R2, R3, R4, R5, R6, R7,...
US-9,889,129 Method of modulating ribonucleotide reductase
A method of modulating ribonucleotide reductase activity in a neoplastic cell includes administering to the cell an amount of a ribonucleotide reductase...
US-9,889,128 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition
Disclosed is the synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and...
US-9,889,127 Method of inhibiting mutant C-KIT
The present invention includes a method of reducing or inhibiting the kinase activity of C-KIT mutant tyrosine kinase activity in a cell or a subject, and the...
US-9,889,126 Use of naratriptan in the treatment of rosacea
Described herein is a method of using a topical, pharmaceutical composition, particularly a dermatological composition, comprising naratriptan to treat rosacea...
US-9,889,125 Methods for treating heartburn, gastric bleeding or hemorrhage in patients receiving clopidogrel therapy
The present invention relates to methods of treating heartburn in a patient receiving clopidogrel therapy. In another aspect, the present invention relates to...
US-9,889,124 Crystalline N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridiny- l)phenyl]acetamide...
The present invention relates to the crystalline mono mesylate monohydrate salt of N-[5 ...
US-9,889,123 Polymorphs of deuterated omega-diphenylurea or salts thereof
The invention relates to polymorphs of deuterated omega-diphenylurea or salts thereof. In particular, the invention provides polymorphs of ...
US-9,889,122 Positive allosteric modulators of nicotinic acetylcholine receptor
The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising...
US-9,889,121 Heterocyclylalkyne derivatives and their use as modulators of mGluR5 receptors
This invention relates to compounds of formula I, ##STR00001## their use as allosteric modulators of mGluR5 receptor activity, pharmaceutical compositions...
US-9,889,120 Combination drug therapies for cancer and methods of making and using them
In alternative embodiments, provided are therapeutic combinations, pharmaceutical compositions, formulations, kits and devices for treating, preventing or...
US-9,889,119 Amorphous tecovirimat preparation
Disclosed are methods for the preparation of amorphous N-[(3aR,4R,4aR,5aS,6S,6aS)-3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-et- ...
US-9,889,118 Use of amisulpride as an anti-emetic
Amisulpride is used in the therapy of nausea, vomiting or retches. The therapy may utilize a novel injectable formulation, in unit dosage form, comprising less...
US-9,889,117 Method for treating and/or delaying the degeneration of Purkinje cells
A method for treating and/or delaying the degeneration of Purkinje cells in a subject is provided. The method comprises administering to a subject in need...
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