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Patent # Description
US-9,909,172 Non-thermal cycling for polymerase chain reaction
Techniques, systems, and devices are disclosed for non-thermal cycling of polymerase chain reaction (PCR). In one aspect, a method for cycling PCR includes...
US-9,909,171 Thermo-controllable high-density chips for multiplex analyses
The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required....
US-9,909,169 Allele-specific amplification of nucleic acids using blocking oligonucleotides for wild type suppression
A method is provided for allele-specific amplification, utilizing a blocking oligonucleotide including at least one nucleotide with a base covalently modified...
US-9,909,168 Method of synthesizing nucleic acid
The present invention relates to an oligonucleotide having a novel structure and a method of synthesizing nucleic acid by using the same as a primer. This...
US-9,909,167 On-slide staining by primer extension
A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an...
US-9,909,166 Method and kit for the detection of nucleic acids
Method for the determination of the concentration of a type of specific nucleic acids (10) in a sample, wherein the sequences of the specific nucleic acid (10)...
US-9,909,165 Nucleic acid preparation method
A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least...
US-9,909,164 Method for preparing sample for nucleic acid amplification reaction and preparation device of sample for...
There is provided a method for preparing a sample for a nucleic acid amplification reaction, the method including a heating step of applying heat to a nucleic...
US-9,909,163 Engineered enzymes with methionine-gamma-lyase enzymes and pharmacological preparations thereof
Methods and composition related to the engineering of a novel protein with methionine-.gamma.-lyase enzyme activity are described. For example, in certain...
US-9,909,162 Bacterial detection cartridge
Described herein are methods and apparatus for rapid detection of microorganisms in biological samples (e.g. blood) for analysis to determine the presence or...
US-9,909,161 Method and system for evaluation of grafts
A method and system for evaluating the competence for transplantation of a graft sample containing cells capable of multinucleation are provided. In one form,...
US-9,909,160 Modulators of alpha-synuclein toxicity
Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity....
US-9,909,159 Highly selective nucleic acid amplification primers
This invention discloses multi-part primers for primer-dependent nucleic acid amplification methods. Also disclosed are primer-dependent nucleic acid...
US-9,909,158 Method of producing sugar solution including washing with aqueous alkaline and inorganic salt solutions
A method of producing a sugar liquid from a cellulose-containing biomass includes (1) hydrolyzing a cellulose-containing biomass using a filamentous...
US-9,909,156 Lov-D acyltransferase mediated acylation
Methods for the improved acylation of chemical substrates using LovD acyltransferases, thioesters having acyl groups, and (i) thiol scavengers and/or (ii)...
US-9,909,155 Structuring fats and methods of producing structuring fats
Recombinant DNA techniques are used to produce oleaginous recombinant cells that produce triglyceride oils having desired fatty acid profiles and regiospecific...
US-9,909,154 Methods for producing dicarboxylic acids
The present invention provides methods of producing dicarboxylic acids. The methods involve incubating a fatty acid or hydrocarbon substrate with an enzyme to...
US-9,909,153 Compositions and methods for biological production of fatty acid derivatives
The present disclosure provides compositions and methods for biologically producing fatty acid derivatives, such as fatty alcohols, from recombinant C.sub.1...
US-9,909,152 Enhanced itaconic acid production in Aspergillus with increased LaeA expression
Fungi, such as Aspergillus niger, having a dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase (Alg3) gene genetic inactivation, increased expression...
US-9,909,151 Biological methods for preparing a fatty dicarboxylic acid
Provided are engineered microorganisms capable of producing fatty dicarboxylic acids and products expressed by such microorganisms. Also provided are biological...
US-9,909,150 Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol,...
Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in...
US-9,909,149 DHAD variants for butanol production
Dihydroxy-acid dehydratase (DHAD) variants that display increased DHAD activity are disclosed. Such enzymes can result in increased production of compounds from...
US-9,909,148 Fermentative production of alcohols
The invention relates to the fields of industrial microbiology and alcohol production. The invention also relates to the development of a microorganism capable...
US-9,909,147 Enzymatic hydroxylation of aliphatic hydrocarbon
The invention relates to enzymatic methods for hydroxylation in position 2 or 3 of substituted or unsubstituted, linear or branched aliphatic hydrocarbons.
US-9,909,146 Production of alkenes by enzymatic decarboxylation of 3-hydroxyalkanoic acids
The present invention relates to a method for generating alkenes biologically. It relates more particularly to a method for producing terminal alkenes by...
US-9,909,145 Method for producing fragrant alcohols
This invention relates generally to methods and compositions for producing a sesquiterpene alcohol comprising contacting a sesquiterpene with a p450 polypeptide...
US-9,909,144 Compositions and methods for producing isoprene
The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.
US-9,909,143 Engineered subcellular compartments
This disclosure describes a cell that includes an engineered subcellular compartment that generally includes a proteinaceous shell that includes at least one...
US-9,909,142 Composition and methods for highly efficient gene transfer using AAV capsid variants
Compositions and methods for AAV mediated gene therapy are disclosed. AAV vectors comprise protein capsid variants comprising therapeutically beneficial...
US-9,909,141 Potato transformation vector pSIM1678
A potato transformation vector, pSIM1678 is disclosed. The invention relates to the potato transformation vector which contains an expression cassette for the...
US-9,909,140 AXMI-115, AXMI-113, AXMI-005, AXMI-163 and AXMI-184: insecticidal proteins and methods for their use
Compositions and methods for conferring insecticidal activity to host cells are provided. Compositions comprising a coding sequence for a delta-endotoxin...
US-9,909,139 Plant germplasm resistant to RNA viruses
Disclosed is a dsRNA construct used to silencing specific eukaryotic translation initiation factor in plants to produce a plant resistant to viruses such as...
US-9,909,138 Drought resistance in plants: pectinesterase
The present invention relates to a new method for increasing drought resistance of a plant. The method encompasses the impairment of the expression of a gene or...
US-9,909,137 Papaver somniferum strain with high concentration of thebaine
The present invention is directed to an improved poppy straw, concentrate of poppy straw and opium of Papaver somniferum for the production of thebaine...
US-9,909,136 Methods and compositions for altering lignin composition in plants
The invention provides methods for decreasing lignin content in plants by reducing expression of a folylpolyglutamate synthetase 1 (FPGS1) coding sequence in...
US-9,909,135 Transgenic plants having altered DAHP synthase activity
The present invention provides transgenic plants comprising 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate (DAHP) Synthase that is insensitive to feedback...
US-9,909,134 RNA-Seq transcriptome analysis of spirodela dormancy without reproduction and identification of molecular...
Compositions and methods are provided for altering carbon partitioning in biomass isolated from Duckweed.
US-9,909,133 Root specific expression conferred by chimeric gene regulatory elements
Provided are constructs and methods for expressing a transgene in plant cells and/or plant tissues using chimeric gene regulatory elements.
US-9,909,132 Formulations and methods for control of weedy species
A formulation is provided for application to a host plant to reduce, inhibit or impair one or more of growth and development of the host plant. A method of...
US-9,909,131 Optimal soybean loci
As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.
US-9,909,130 Production of carotenoids in oleaginous yeast and fungi
The present invention provides systems for producing engineered oleaginous yeast or fungi that express carotenoids.
US-9,909,129 Biosynthetic pathways and methods
This disclosure describes a recombinant microbial cells and methods of making and using such recombinant microbial cells. Generally, the recombinant cells may...
US-9,909,128 Splice modulating oligonucleotides that inhibit cancer
A method of treating cancer in a subject is provided. The method includes administering a splice modulating oligonucleotide to the subject in an amount...
US-9,909,127 Inhibitor for inhibiting avian influenza virus and a pharmaceutical composition containing the same
Provided is non-coded RNA of in-vivo infected microorganisms, parasitic microorganisms, symbiotic microorganisms and identification and application thereof....
US-9,909,126 Treatment of Adiponectin (ADIPOQ) related diseases by inhibition of natural antisense transcript to an...
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of an Adiponectin (ADIPOQ), in particular, by...
US-9,909,125 Molecular targets for selective eradication of senescent cells
Compositions and methods for selective partial or complete eradication of senescent cells in a mammal are provided. The involves inhibition of the expression of...
US-9,909,124 Compounds and methods for modulating apolipoprotein C-III expression for improving a diabetic profile
Provided herein are improved compounds, compositions and associated methods for reducing expression of ApoCIII mRNA and protein in a subject having, or at risk...
US-9,909,123 Antisense molecules for treatment of Staphylococcus aureus infection
Disclosed are antisense molecules and compositions for the treatment of Staphylococcus aureus infection. The antisense molecules and compositions comprise...
US-9,909,122 Compositions and methods of nucleic acid-targeting nucleic acids
This disclosure provides for compositions and methods for the use of nucleic acid-targeting nucleic acids and complexes thereof.
US-9,909,121 Expanded radix for polymeric tags
A method having steps of (a) providing nucleic acids having a tag sequence (N.sub.1).sub.n(N.sub.2).sub.n . . . (N.sub.x).sub.n, wherein N.sub.1, N.sub.2 and...
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