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Patent # Description
US-9,918,995 Ciclesonide for the treatment of airway disease in horses
The invention relates to the field of medicine, in particular to the field of veterinary medicine. The invention relates to glucocorticoids, especially...
US-9,918,994 Compositions and methods for muscle regeneration using prostaglandin E2
Provided herein are compositions, methods, and kits for proliferating muscle cells by exposing the muscle cells to a prostaglandin E2 (PGE2) compound or...
US-9,918,993 Pharmaceutical compositions for anesthesiological applications
Pharmaceutical compositions and methods are described, the compositions comprising a benzodiazepine-based compound, a NMDA antagonist, a .beta.-blocker and...
US-9,918,992 Combination therapies for the treatment of Alzheimer's disease and related disorders
The present invention relates to combination therapies for treating Alzheimer's disease or an amyloidosis-associated pathological condition comprising...
US-9,918,991 Topical antimicrobial compositions and methods of using same
The invention includes a method of treating a mammal comprising topically applying an aqueous composition to a target site on the mammal, wherein the aqueous...
US-9,918,990 Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors
The present invention relates to compounds represented by the general Formula I which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are...
US-9,918,989 Combination therapies for malaria
The present disclosure provides methods for treating or preventing malaria by administration of a protein kinase inhibitor and optionally one or both of a...
US-9,918,988 Ammonium derivatives for the treatment of hepatitis C
Compounds of Formula I, including pharmaceutically acceptable salts thereof, are set forth, in addition to compositions and methods of using these compounds....
US-9,918,987 Substituted xanthine derivatives
This invention relates to novel compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. For example, this invention...
US-9,918,986 Methods and compounds for preventing osteoarthritis
The present application relates to therapeutics and pharmaceutical compositions, their use and also methods for preventing post-traumatic osteoarthritis, early...
US-9,918,985 Compounds and their use as BACE inhibitors
The present invention relates to compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic...
US-9,918,984 Methods and compositions for treating diabetes, metabolic syndrome and other conditions
Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are...
US-9,918,983 Suicidal LSD1 inhibitors targeting SOX2-expressing cancer cells
Disclosed are inhibitors of lysine-specific demethylase I (LSD1); synthetic methods for making the compounds; pharmaceutical compositions comprising the...
US-9,918,982 Oral drug delivery system
Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of...
US-9,918,981 Liquid buprenorphine formulations
The invention provides liquid formulations containing buprenorphine, a pharmaceutically acceptable salt thereof, or a derivative thereof. The invention further...
US-9,918,980 Method of treating dyskinesia
Methods of treating patients with dyskinesias, by administering a therapeutically effective amount of a dual-action .mu.-opioid receptor ...
US-9,918,979 Process of preparing low ABUK oxymorphone hydrochloride
An improved method for the preparation of the low ABUK oxymorphone hydrochloride is provided. The oxymorphone hydrochloride is produced by hydrogenating a...
US-9,918,978 Compositions of buprenorphine and .mu. antagonists
The invention relates to a composition comprising buprenorphine and .mu. opioid receptor antagonist, wherein the composition is characterized by an Agonist...
US-9,918,977 Crystalline forms of a prolyl hydroxylase inhibitor
The present disclosure relates to crystalline solid forms of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid, the process of...
US-9,918,975 Method for improving dissolution of anticoagulant agent
It is desired to provide a pharmaceutical composition containing a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, or a...
US-9,918,974 Pyridone derivatives as rearranged during transfection (RET) kinase inhibitors
This invention relates to novel compounds which are inhibitors of the Rearranged during Transfection (RET) kinase, to pharmaceutical compositions containing...
US-9,918,973 Sustained release aminopyridine composition
A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a...
US-9,918,972 Treatment of leukemia with artemisinin derivatives and combinations with other antineoplastic agents
Methods of treating cancer, such as leukemia, via administration of therapeutically effective amounts of artemisinins and second agents are detailed herein. The...
US-9,918,971 Aerosol formulations of granisetron and uses thereof
Aerosol formulations of granisetron useful for pulmonary delivery are provided. The formulations are useful in the reduction, elimination or prevention of...
US-9,918,970 Pharmaceutical composition comprising solifenacin
Disclosed is a pharmaceutical composition comprising a complex between solifenacin or a pharmaceutically acceptable salt thereof and an ion exchange resin, and...
US-9,918,969 Substituted oxopyridine derivatives and use thereof as factor XIa/plasma
The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the...
US-9,918,968 Rapamycin analogs targeting proteasome function in the treatment of cancer
The invention provides for treatment of cancers using a rapamycin analog, optionally including bortezomib. In particular, the invention addresses the treatment...
US-9,918,967 Thiazole derivatives for treating dyskinesias caused by a chemical treatment
The invention relates to the use of derivatives of thiazoles having general formula (I) for the preparation of a medicament for the treatment or prevention of...
US-9,918,966 Anti-cancer compositions and methods
Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present...
US-9,918,965 Self-emulsifying formulations of DIM-related indoles
Disclosed herein are self-emulsifying compositions and formulations of Diindolylmethane ("DIM") and certain derivatives of DIM, their uses and methods of...
US-9,918,964 Reducing platelet activation, aggregation and platelet-stimulated thrombosis or blood coagulation by reducing...
It has been discovered that inhibiting mitochondrial respiration in platelets reduces platelet activation or platelet aggregation. Certain heterocyclic...
US-9,918,963 Therapeutic agent for disease based on inhibitory effect of macrophage migration inhibitory factor
A method for treating the relapsing-remitting or secondary progressive multiple sclerosis at the time of relapse, by administering a benzopyran derivative of...
US-9,918,962 Methods and compositions for inhibition of ATR and FANCD2 activation
This invention is announcing a composition of flavonoid skeleton in the formula I or formula II compound, wherein each of the substituents is given the...
US-9,918,961 Cannabinoid inhaler and composition therefor
The present invention provides a cannabinoid inhaler, compositions, and methods for delivering a cannabinoid composition to a subject. The cannabinoid...
US-9,918,960 Topical oily foam compositions
Topical alcohol-free thermo labile oily foam composition comprising (i) at least one active pharmaceutical ingredient or ectoparasitic active ingredient; (ii)...
US-9,918,959 TLR-independent small molecule adjuvants
A TLR-independent adjuvant compound that corresponds in structure to Formula I, below, or its pharmaceutically acceptable salt is disclosed in ##STR00001## ...
US-9,918,958 Treatment for hypoxia
The invention provides a method for treating hypoxia in a normal subject, comprising administering 5-HMF to the subject.
US-9,918,957 Methods for making compound particles
Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean...
US-9,918,956 Chlorogenic acid powder-injection and preparation method thereof
The present invention provides a chlorogenic acid powder-injection. The chlorogenic acid powder-injection is prepared from the following raw materials in parts...
US-9,918,955 Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular,...
US-9,918,954 Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular,...
US-9,918,953 Composition containing eicosapentaenoic acid alkyl ester, and method for producing same
Provided are: an eicosapentaenoic acid alkyl ester-ontaining composition which comprises 96-99 area % of an eicosapentaenoic acid alkyl ester, wherein the...
US-9,918,952 Powderous formulation
The present invention relates to a powderous formulation comprising powder particles. These powder particles do comprise polyunsaturated oils, especially...
US-9,918,951 Method for improving storage stability of glutathione
The invention provides a method of improving the preservation stability of glutathione in a solid composition containing glutathione and arginine. In...
US-9,918,950 Targeted treatment of anerobic cancer
The present invention relates to a pharmaceutical cocktail and methods of treatment involving said cocktail, in particular, a combination of effective amounts...
US-9,918,949 Emesis treatment
A method of treating or preventing emesis through the administration of an effective dosage of a 2-(amino)tetralin compound in which one of the S or R...
US-9,918,948 Methods and compositions for treating symptoms associated with post-traumatic stress disorder using cyclobenzaprine
The present invention relates to methods for the treatment or prevention of symptoms associated with post-traumatic stress disorder, and related pharmaceutical...
US-9,918,947 Composition of olivetol and method of use to reduce or inhibit the effects of tetrahydrocannabinol in the human...
Embodiments of the present invention relate to the use of a therapeutically-effective amount of Olivetol to reduce, eliminate, inhibit or alleviate the...
US-9,918,946 Petrolatum composition
A petrolatum composition comprises from 10 to 60 wt % of a wax having an average number of carbon atoms per molecule of between 25 and 70, and having between 5...
US-9,918,945 Ropinirole-containing patch and package thereof
A ropinirole-containing patch comprises an adhesive agent layer and a support layer, the adhesive agent layer containing ropinirole and/or a pharmaceutically...
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