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Patent # Description
US-9,925,272 Anti-theophylline antibodies and methods of use
The invention provides anti-theophylline antibodies and methods of using the same.
US-9,925,271 Targeted pharmacological chaperones
The present invention relates to the preparation and use of therapeutic compounds for the treatment of diseases at specific subcellular target areas such as...
US-9,925,270 bFGF-polymer conjugates, methods for making the same and applications thereof
A heparin mimicking polymer, its conjugate with bFGF, and method of making and using the same are disclosed. In particular, described herein are conjugates of...
US-9,925,269 Phospholipid ether analogs as cancer-targeting drug vehicles
The present invention is directed to therapeutic compounds capable of targeting cancer cells and cancer stem cells. The present invention is further directed to...
US-9,925,268 Drug-containing implants and methods of use thereof
The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The...
US-9,925,267 Polylactide compositions and uses thereof
The present invention provides compositions and methods relating to polylactides which may be used for drug delivery (e.g., parenteral delivery), wherein an...
US-9,925,266 Gelling formulation based on calcium gluconate
The invention related to a gelling formulation including calcium gluconate in solution in water and a poloaxmer and to the use thereof in the treatment of...
US-9,925,265 Methods of treating or preventing stent thrombosis
The present invention is directed to the following: methods of treating or preventing stent thrombosis using pharmaceutical compositions comprising cangrelor...
US-9,925,264 Non-aqueous patch
Non-aqueous patches comprising lidocaine, which is not dissolved and is present in a crystalline state, have poor permeability to the skin. Therefore,...
US-9,925,263 Liquid pharmaceutical formulations for injection comprising procaine and uses thereof
Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of proteins have been developed. Such formulations can be rapidly and conveniently...
US-9,925,262 Kits comprising formulations of anti-C5 antibodies
The present disclosure relates to, inter alia, stable aqueous solutions comprising a high concentration of an antibody that binds to human complement component...
US-9,925,261 Methods of treating pre-eclampsia or eclampsia
Disclosed herein are methods for treating pre-eclampsia and eclampsia using compounds that increase VEGF or PlGF levels or compounds that decrease sFlt-1...
US-9,925,260 Treatment for bone diseases
The invention relates to the treatment of bone disorders. In particular, the invention is directed to the use of a dosing holiday to help overcome the...
US-9,925,259 Immunogenic polypeptide surface layer-expressing bifidobacterium
Provided is a gene for expressing an immunogenic polypeptide on the cell surface of a bifidobacterium, and the gene includes a gene encoding the immunogenic...
US-9,925,258 Replication-competent VSV-HIV Env vaccines
The present relation relates to recombinant vesicular stomatitis virus for use as prophylactic and therapeutic vaccines for infectious diseases of AIDS. The...
US-9,925,257 Vaccine and therapeutic delivery system
The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed...
US-9,925,256 Multivalent PCV2 immunogenic compositions and methods of producing such compositions
An improved method for recovering the protein expressed by open reading frame 2 from porcine circovirus type 2 is provided. Also provided is recombinant PCV2...
US-9,925,255 Multivalent PCV2 immunogenic compositions and methods of producing such compositions
An improved method for recovering the protein expressed by open reading frame 2 from porcine circovirus type 2 is provided. Also provided is recombinant PCV2...
US-9,925,254 Synthetic antigen constructs against Campylobacter jejuni
The invention relates to immunogenic synthetic constructs capable of inducing an immune response against Campylobacter jejuni (C. jejuni) in a subject...
US-9,925,253 Compositions produced using enteric pathogens and methods of use
The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such as E. coli...
US-9,925,252 Antigenic compositions and methods
Multilayer films are described that include polypeptide epitopes and a toll-like receptor ligand. The multilayer films are capable of eliciting an immune...
US-9,925,251 Treatments for Mycobacterium tuberculosis
The technology described herein relates to treatments for tuberculosis which target the ClpP1P2 protease complex, including ClpC1. Further embodiments relate to...
US-9,925,250 Method of treating proteinuria in pregnancy
A therapeutic agent for the treatment of toxemia, preeclampsia and eclampsia and a method for preparing the therapeutic agent are disclosed. The therapeutic...
US-9,925,249 Compositions and methods for treating celiac sprue disease
The invention provides compositions and methods for treating celiac sprue.
US-9,925,248 Methods and compositions for RNA-guided treatment of HIV infection
A method of inactivating a proviral DNA integrated into the genome of a host cell latently infected with a retrovirus by treating the host cell with a...
US-9,925,247 IL-15-based molecules and methods of use thereof
The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious...
US-9,925,246 Mitigation of cutaneous injury with IL-12
The present application relates to treatment of cutaneous wounds using IL-12. The methods of the invention result in improved wound closure. The methods...
US-9,925,245 Pegylated interleukin-10
Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for...
US-9,925,244 Treatment of warts in non-immunosuppressed patients
A method for treating warts includes administering to a patient with warts a composition having an autologous, matched allogenic, donor tissue source of mixed,...
US-9,925,243 Chimeric fibroblast growth factor (FGF) 2/FGF1 peptides and methods of use
The present disclosure provides chimeric proteins having an N-terminus coupled to a C-terminus, wherein the N-terminus comprises an N-terminal portion of...
US-9,925,242 Methods of using compositions comprising variants and fusions of FGF19 polypeptides for treatment of...
The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of...
US-9,925,241 Mutated fibroblast growth factor (FGF) 1 and methods of use
The present disclosure provides FGF1 mutant proteins, such as those having an N-terminal deletion, point mutation(s), or combinations thereof, which can reduce...
US-9,925,240 Methods of treating and preventing cancer drug resistance
Provided herein are combination therapies for the treatment of pathological conditions, such as cancer, using an antagonist of FGFR signaling.
US-9,925,239 Treatment of X-linked hypohidrotic ectodermal dysplasia with a fusion EDA1 protein
The invention relates to methods for the temporal administration of EDA agonists, in particular EDI200, which correlate to optimal therapeutic response windows...
US-9,925,238 Use of peptide for treating angiogenesis-related diseases
Disclosed herein are methods for treating an angiogenesis-related condition or disease in a subject in need thereof. Said method includes administering to the...
US-9,925,237 Polypeptide-polymer conjugates and methods of use thereof
The present invention provides polypeptide-polymer conjugates. A subject polypeptide-polymer conjugate is useful in a variety of applications, which are also...
US-9,925,236 Reconstituted HDL formulation
The present invention relates to reconstituted high density lipoprotein (rHDL) formulations comprising an apolipoprotein, a lipid and a lyophilization...
US-9,925,235 Tilapia piscidins for use in enhancement of wound healing
A method for enhancing wound healing or treating methicillin-resistant Staphylococcus aureus (MRSA) infection in a wound comprising administering a subject in...
US-9,925,234 Vasopressin formulations for use in treatment of hypotension
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time at...
US-9,925,233 Vasopressin formulations for use in treatment of hypotension
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time at...
US-9,925,232 Methods and compositions comprising desmopressin in combination with a 5-alpha reductase inhibitor
The invention provides methods and compositions for use of desmopressin in combination with a 5-alpha reductase inhibitor. The methods and compositions are...
US-9,925,231 Formulations of guanylate cyclase C agonists and methods of use
The invention provides low-dose formulations of guanylate cyclase-C ("GCC") agonist peptides and methods for their use. The formulations of the invention can be...
US-9,925,230 Augmenting the immune response by promoting cell death of immune cells
Methods and products for producing an antigen specific immune response are provided. The methods involve administration of a caspase inhibitor to a subject.
US-9,925,229 Anti-aging composition method
An anti-aging composition, having anti-oxidant and anti-inflammatory properties, comprised of an effective amount of Turmeric Root Extract, Olive Leaf Extract,...
US-9,925,228 Medicinal orobancheace extracts
Pharmaceutical extracts from Egyptian broomrape have proven efficacy against HCV and NAFLD. Compositions and method of making and using same are provided.
US-9,925,227 Composition for treating obesity and method of using the same
The present invention provides a composition for a medicinal or health effect of a treatment of liver fat and body fat, a reduction of blood pressure, an...
US-9,925,226 Method for manufacturing water-soluble medical amber crystals
A method for manufacturing water-soluble medical amber causes that original great molecular groups of medical amber crystals are decomposed into hydrophilic...
US-9,925,225 Treatment and prophylaxis for gastroesophageal reflux disease
An embodiment is a method of preventing, mitigating or treating Gastroesophageal Reflux Disease (GERD) that includes administering an effective amount of a...
US-9,925,224 Bacterial strains belonging to the genus bifidobacterium for use in the treatment of hypercholesterolaemia
Selected bacterial strains belonging to the genus Bifidobacterium for use in the treatment of hypercholesterolaemia are described. In particular, a food...
US-9,925,223 Methods for making and using antimicrobial peptides
Provided herein are genetically modified microbes. In one embodiment, a genetically modified microbe includes an exogenous polynucleotide comprising a...
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