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Patent # Description
US-9,931,361 Treatment to promote wound healing
The invention relates to a field of tissue repair and regeneration. More particularly, the invention relates to a composition for promoting cutaneous wound...
US-9,931,360 Isolated liver stem cells
A method of treating liver-based inborn, metabolic deficiencies is disclosed by treatment of an individual, such as a patient suffering from liver-based inborn,...
US-9,931,359 Methods and compositions for infusion of transiently engrafting, selected populations of allogeneic lymphocytes...
The invention provides methods and compositions for administration of allogeneic lymphocytes as an exogenous source of CD4+ T cell help for endogenous,...
US-9,931,358 Direct compression polymer tablet core
The present invention provides a tablet core which comprises at least about 95% by weight of an aliphatic amine polymer. The invention also provides a method of...
US-9,931,357 Use of gastrointestinally administered porous enteron sorbent polymers to prevent or treat radiation induced...
Disclosed herein are compositions and methods for preventing or treating acute or chronic oral mucositis, esophagitis, enteritis, colitis, or gastrointestinal...
US-9,931,356 Pharmacokinetics of S-adenosylmethionine formulations
Compositions and methods to improve the pharmacokinetic profile of S-Adenosylmethionine (SAMe) are provided, as are methods of treating various disorders using...
US-9,931,355 Combination of compounds derived from gallic acid for the treatment of cancer
The invention relates to a combination of compounds derived from gallic acid, with an antitumoral and antimetastatic activity via a mechanism that involves the...
US-9,931,353 Method for treating cerebral amyloid angiopathy using pharmacological chaperones to increase the activity of...
The present invention relates to a method for treating an individual having Cerebral Amyloid Angiopathy by using pharmacological chaperones to increase the...
US-9,931,352 Neridronic acid for treating complex regional pain syndrome
Oral dosage forms of osteoclast inhibitors, such as neridronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
US-9,931,351 Method for improving leptin resistance
The present invention provides a compound of formula (I) which improves leptin resistance, a pharmaceutical composition comprising the compound, a method for...
US-9,931,350 Anti-infective and osteogenic compositions and methods of use
Cationic steroidal antimicrobials ("CSAs" or "ceragenins") and methods of making and using the same. Particularly advantageous uses include treating infections...
US-9,931,349 Steroid hormone pharmaceutical composition
This disclosure provides a novel pharmaceutical composition for delivering steroid hormones to a patient in need thereof.
US-9,931,348 Vanadium compounds as therapeutic adjuncts for cartilage injury and repair
A method for repairing an injury of cartilage in a patient by local administration of an organovanadium agent or use of an implantable device for delivery of an...
US-9,931,347 Pharmaceutical compound
Provided is a tryptophan-2,3-dioxygenase (TDO) and/or indoleamine-2,3-dioxygenase (IDO) inhibitor compound for use in medicine, which compound comprises the...
US-9,931,346 Serotonin-norepinephrine reuptake inhibitors (SNRIs) and Sigma receptor ligands combinations
The invention refers to a synergistic combination comprising a Sigma ligand of general formula (I), and a Serotonin-Norepinephrine Reuptake Inhibitor (SNRI), a...
US-9,931,345 Transient protection of normal cells during chemotherapy
This invention is in the area of improved compounds, compositions and methods of transiently protecting healthy cells, and in particular hematopoietic stem and...
US-9,931,344 Layered sustained-release microbeads and methods of making the same
A layered microbead suitable for incorporating into a non-prescription consumable product is disclosed. The layered microbead may include a core and at least...
US-9,931,343 Deuterated baricitinib
The present invention in one embodiment provides a compound of Formula I: ##STR00001## or a pharmaceutically acceptable salt thereof, wherein the variables...
US-9,931,342 Compositions and methods for the treatment of cancer
The present disclosure provides compositions and methods for the treatment of cancer, relating to the specific inhibition of Abelson (ABL) kinases.
US-9,931,341 Antagonist of the fibroblast growth factor receptor 3 (FGFR3) for use in the treatment or the prevention of...
The present invention relates to the treatment or prevention of skeletal disorders, in particular skeletal diseases, developed by patients that display abnormal...
US-9,931,340 Pyridazinone compounds and their use as DAAO inhibitors
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R.sup.1 and R.sup.2 are as defined in the...
US-9,931,339 Substituted pyrrolo[2,3-b]quinoxalines for cancer therapy
Compounds, including quinoxaline derivatives of formula I, for use in the treatment of cancer are described. In general, the compounds inhibit the import of...
US-9,931,338 Syk inhibitors
The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and...
US-9,931,337 Systems and methods for treating an opioid-induced adverse pharmacodynamic response
Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient...
US-9,931,336 Combination therapy
Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound...
US-9,931,335 Desethylhydroxychloroquine for the treatment of diseases associated with inflammation
Compositions and methods are provided for inhibiting or treating the early and established stages of inflammatory diseases by administration of an effective...
US-9,931,334 Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-- 3-carboxamide
The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline- -3-carboxamide (Compound 1),...
US-9,931,333 Compositions and methods for treating or preventing atrial fibrillation
The present invention provides compositions and methods for treating or preventing atrial fibrillation (AF). In particular, the present invention provides...
US-9,931,332 Compositions and methods for treating primary effusion lymphoma
Methods for treating primary effusion lymphoma (PEL) are provided. The methods include administering to a patient in need thereof an effective amount of an...
US-9,931,331 Pharmaceutical composition for preventing or treating cancer, containing proteasome inhibitor and loperamide as...
The present invention relates to an anticancer supplement containing loperamide as an active ingredient. More specifically, a proteasome inhibitor alone cannot...
US-9,931,330 Methods and devices for the treatment of ocular diseases in human subjects
Methods and devices are provided for targeted non-surgical administration of a drug formulation to the suprachoroidal space (SCS) of the eye of a human subject...
US-9,931,329 Phenyl triazole derivative and its use for modulating the GABA.sub.A receptor complex
Phenyl triazole derivative (specifically, 1-[6-[[5-(2-fluorophenyl)-3-methyl-triazol-4-yl]methoxy]-3-pyridyl]imidaz- ole-4-carbonitrile or a pharmaceutically...
US-9,931,328 Topical retinoid compositions
The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active...
US-9,931,327 Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors
Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and the treatment of certain conditions...
US-9,931,326 Composition comprising torasemide and baclofen for treating neurological disorders
The present invention relates to compositions and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid .beta....
US-9,931,325 Methods for treating irritable bowel syndrome (IBS)
The present invention provides new methods and kits for treating IBS; treating IBS in females; treating IBS in older subjects; and treating IBS in non-white...
US-9,931,324 Indolizine derivatives and their use in neurodegenerative diseases
The present invention relates to indolizine compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of P2X7, and for the...
US-9,931,323 Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use
Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically...
US-9,931,322 Treatment of BRCA1-defective cancer or resistant cancers
Provided herein are methods of treating cancer in a subject, by administering COH29 ((N-(4-(3,4-dihydroxyphenyl)-5-phenylthiazol-2-yl)-3,4-dihydroxybenzamide- ...
US-9,931,321 Therapeutic agent for dyslipidemia
The present invention addresses the problem of providing a pharmaceutical combination composition and drug combinations for the prevention and/or treatment of...
US-9,931,320 Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting...
US-9,931,319 Carboxamide derivatives
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; ##STR00001## a method for manufacturing the compounds...
US-9,931,318 Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation
The present invention provides methods of improving cognitive and motor deficits associated with central nervous system (CNS) disorder or condition in an...
US-9,931,317 Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
The present invention relates to compounds of formula I: ##STR00001## in which n, m, X, Y.sub.1, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are defined in...
US-9,931,316 Antiviral activity from medicinal mushrooms and their active constituents
Compounds having unique antiviral properties found in mushroom mycelium and their analogs are extracted, concentrated, isolated or manufactured to create...
US-9,931,315 Method of selectively inhibiting Ras-mediated tumor growth in humans
Disclosed are compounds, for example, a compound of formula I, ##STR00001## wherein R, R.sub.0, R.sub.1-R.sub.8, n, X, Y, Y', and E are as described herein,...
US-9,931,314 Method for treating skin cancer
A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the...
US-9,931,313 Methods of treating proliferative disorders with malate or derivatives thereof
The present invention relates to methods, compositions, and diagnostic tests for treating and diagnosing proliferative disorders, such as cancel-, that result...
US-9,931,312 Lipid composition for the prevention or treatment of skin problems
The invention relates to a novel lipid composition. Further, the invention relates to the use of a lipid composition for the treatment, alleviation and...
US-9,931,311 Treating critically ill patients with intravenous ibuprofen
Methods of treating at least one condition chosen from pain, inflammation, and fever in a critically ill patient in need thereof, comprising administering to...
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