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Patent # Description
US-9,932,588 Inhibition of oxidative stress in atrial fibrillation
Disclosed herein are pharmaceutical compositions and methods for inhibiting oxidative stress in a subject having atrial or ventricular arrhythmias, ventricular...
US-9,932,587 Methods of identifying and treating poor prognosis cancers
The present invention relates generally to methods for identifying cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis...
US-9,932,586 Compositions and methods for inhibiting gene expression of LPA
RNA interference (RNAi) agents and RNAi agent conjugates for inhibiting the expression of the LPA (apo(a)) gene are described. Pharmaceutical compositions...
US-9,932,585 Manipulating microRNA for the management of neurological diseases or conditions and compositions related thereto
This disclosure relates to manipulating microRNA for the management of neurological disorders and compositions related thereto. In certain embodiments, the...
US-9,932,584 Interfering RNA delivery system and uses thereof
The invention provides a delivery system comprising a cell penetrating peptide, 10 histidines, and an interfering RNA molecule. The system can be used for...
US-9,932,583 Compositions and methods for treating liver injury
Compositions and methods for detecting, inhibiting, treating, and/or preventing a liver disease or disorder such as cholestasis or fibrotic liver disease are...
US-9,932,582 Materials and methods for modulation of tendon healing
The invention relates to the use of microRNA 29 and precursors and mimics thereof for the modulation of tendon injury and the biomechanical properties of...
US-9,932,581 Compositions and methods for modulating apolipoprotein C-III expression
Provided herein are oligomeric compounds with conjugate groups targeting apoplipoprotein C-III (ApoCIII). In certain embodiments, the ApoCIII targeting...
US-9,932,580 Compositions and methods for modulating HBV expression
Provided herein are oligomeric compounds with conjugate groups. In certain embodiments, the oligomeric compounds are conjugated to N-Acetylgalactosamine.
US-9,932,579 Prevention and treatment of Nosema disease in bees
Compositions and methods for reducing susceptibility and enhancing tolerance to Nosema disease (Nosemosis) using RNA interference technology, and more...
US-9,932,578 Double-stranded oligonucleotide molecules to P53 and methods of use thereof
The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders...
US-9,932,577 Methods for multiplexing recombinase polymerase amplification
This disclosure provides for methods and reagents for rapid multiplex RPA reactions and improved methods for detection of multiplex RPA reaction products. In...
US-9,932,576 Methods for targeted genomic analysis
The invention provides a method for genetic analysis in individuals that reveals both the genetic sequences and chromosomal copy number of targeted and specific...
US-9,932,575 Scaffold proteins derived from plant cystatins
The present invention relates to scaffold proteins derived from plant cystatins and to nucleic acids encoding them. The scaffolds are highly stable and have the...
US-9,932,574 Suspension container for binding particles for the isolation of biological material
A device, method and system is provided for binding particles for the separation and/or isolation of biological materials. In particular, a container is...
US-9,932,573 Labeled enzyme compositions, methods and systems
Disclosed herein are conjugates comprising a biomolecule linked to a label that have biological activity and are useful in a wide variety of biological...
US-9,932,572 Modified Caspase polypeptides and uses thereof
The technology relates in part to compositions comprising modified Caspase-9 polypeptides, compositions comprising nucleic acids coding for modified Caspase-9...
US-9,932,571 Use of galerina marginata genes and proteins for peptide production
The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in...
US-9,932,570 Anthrax lethal factor substrates and methods of use thereof
Disclosed herein is a peptide substrate that is cleaved specifically by anthrax lethal factor (LF), and assays for detecting the presence of anthrax lethal...
US-9,932,569 Chimeric antibacterial polypeptides
Provided herein are antibacterial compositions and methods of making and using the compositions.
US-9,932,568 Peptide linkers for polypeptide compositions and methods for using same
Disclosed herein are novel peptide linkers and polypeptide compositions comprising the linkers (e.g., chimeric polypeptides) and methods of using the...
US-9,932,567 Mutant reverse transcriptase
A mutant MMLV reverse transcriptase that may have an improvement in one or more properties is provided. For example, the present reverse transcriptase is...
US-9,932,566 CIS-blocked guide RNA
This invention discloses reagents and methods for increasing specificity and efficiency of RNA-guided genome editing.
US-9,932,565 Dephosphorylated lysosomal storage disease proteins and methods of use thereof
Provided are substantially dephosphorylated forms of lysosomal storage disease (LSD) proteins, including dephosphorylated forms of iduronate-2-sulfatase (IDS,...
US-9,932,564 Recombinant isfahan viral vectors
Certain embodiments are directed to recombinant vesiculovirus encoding a heterologous polynucleotide and methods of using the same.
US-9,932,563 Compositions and methods for inhibiting gene expressions
A combined packing and assembly method that efficiently packs ribonucleic acid (RNA) into virus like particles (VLPs) has been developed. The VLPs can...
US-9,932,562 Drain down and re-feed of microcarrier bioreactor
The invention provides a method of increasing product yield per culture in a population of product-secreting cells bound to a scaffold, for example, a...
US-9,932,561 Differentiating induced pluripotent stem cells into glucose-responsive, insulin-secreting progeny
This document provides methods and materials related to differentiating iPS cells into glucose-responsive, insulin-secreting progeny. For example, methods and...
US-9,932,560 Use of Zscan4 and Zscan4-dependent genes for direct reprogramming of somatic cells
Disclosed herein is the finding that Zscan4 is an early embryonic factor that facilitates cellular reprogramming. In particular, Zscan4 can replace the...
US-9,932,559 Platform for creating an artificial blood brain barrier
A platform for creating an artificial blood brain barrier including a functional, perfused artificial vessel lined with endothelial cells embedded in a...
US-9,932,558 Compositions and methods for obtaining cells to treat heart tissue
This document relates to compositions containing cardiogenic factors, to methods to obtain cells by culturing initial cells in the presence of such factors; and...
US-9,932,557 Polypeptide, scaffold composition, composition for cartilage tissue restoration, composition for cartilage cell...
A polypeptide having an amino acid sequence in which the number of RGD sequences contained per molecular weight of 10 kDa is not less than 0.30; the number of...
US-9,932,556 Method for in vitro differentiation of blood circulating cells into neuronal-like cells and applications thereof
The present invention relates to a method for in vitro differentiation of a population of blood circulating cells, such as monocytes and preferably pluripotent...
US-9,932,554 Microalgae fermentation using controlled Illumination
Bioreactors and methods for cultivating microalgae are provided herein. The bioreactor and methods include features and modifications to improve heterotrophic...
US-9,932,553 Methods and apparatus for gas stream mass transfer with a liquid
A system for performing a gas-liquid mass transfer includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall...
US-9,932,552 Lateral circulator and agitator for pond cultivation
A lateral circulator for generating agitation or circulation in a cultivation pond is disclosed. The circulator comprises at least a drive pulley and a...
US-9,932,551 Tissue engineered model
A tissue engineered model (TEM) structure, an apparatus and method for making a TEM structure, and methods of using a TEM structure are disclosed. In an...
US-9,932,550 Multi-chambered cell culture device to model organ microphysiology
A cell culture device can include: at least 3 distinct chambers between the top wall and bottom wall. The perimeter walls can include: an internal chamber...
US-9,932,549 Photobioreactor systems and methods
An algal growth system can include a frame and a flexible sheet material that can have a substantially vertical orientation, where the flexible sheet material...
US-9,932,548 System and method for filtering beverages
A filtration system for clarifying a cloudy beverage from at least one tank in which dregs have formed, the clarifying occurring through a cross-flow...
US-9,932,547 Fermentation monitoring and management
A fermentation monitoring system may measure the weight of a fermenting product to determine the progress of fermentation. The weight of a fermenting batch may...
US-9,932,546 Surfactant and detergent compositions containing propoxylated glycerine
The present invention relates generally to surfactant and detergent compositions and, more specifically, to surfactant and detergent compositions containing a...
US-9,932,545 Method of decontaminating machinery contaminated with allergens
A peanut food product with reduced levels of allergenic proteins such as Ala h1/h2/h3 is produced by initiating the germination process in raw peanuts, holding...
US-9,932,544 Play moldable soap composition
The present invention provides a starch-based moldable play composition, including: corn starch; mineral oil; propylene glycol; glyceryl stearate; sodium...
US-9,932,543 Bacterial spore compositions for industrial uses
In one aspect, the present invention is directed to a plant or plant part coated with a composition comprising a bacterial spore and a germinative compound. In...
US-9,932,542 Olefin compositions and their use as cleaning agents
Compositions including olefinic compounds are generally disclosed. In some embodiments, such compositions are cleaning compositions, and can be used to clean...
US-9,932,541 Process for producing ethyl esters of polyunsaturated fatty acids
The present invention relates to a process for producing ethyl esters of polyunsaturated fatty acids, comprising transesterifying triacylglycerols in extracted...
US-9,932,540 Method for refining lipid phases, and use
The invention relates to a method for gently eliminating odorous substances and coloring agents from lipid phases. Said method is easy and inexpensive to carry...
US-9,932,539 Method for extracting lipid from wet biomass
A method for extracting lipid from wet biomass includes a step in which a wet biomass and a first solvent are mixed to prepare a mixture. The method continues...
US-9,932,538 Universal synthetic water displacement multi-purpose penetrating lubricant, method and product-by-process
A universal synthetic water displacement multi-purpose penetrating lubricant product-by-process with the capacity to protect metal surfaces against corrosion,...
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