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Patent # Description
US-9,937,251 Utilization of recombinant influenza viruses and modified vaccinia ankara virus (MVA) with genes that encode...
The present invention concerns to recombinant influenza viruses and modified Vaccinia Ankara viruses (MVA), and to a process for construction of recombinant...
US-9,937,250 Immunogenic tumor associated stromal cell antigen peptides and methods of their use
Immunogenic peptides from tumor associated stromal cell antigens, including combinations of such peptides, are disclosed herein. In some examples the peptides...
US-9,937,249 Mesoporous silica compositions for modulating immune responses
A composition comprising mesoporous silica rods comprising an immune cell recruitment compound and an immune cell activation compound, and optionally comprising...
US-9,937,248 Vaccines for protection from and treatment of alzheimer's disease
Disclosed herein are DNA-based vaccines against amyloid .beta. peptide for use in treating and alleviating Alzheimer's Disease and related conditions. A DNA...
US-9,937,247 Universal cancer vaccine
Described herein are compositions of matter and methods for treating cancer. The compositions comprise altered human telomerase polypeptides containing T cell...
US-9,937,246 Therapeutic acid ceramidase compositions and methods of making and using them
The present invention relates to a therapeutic composition including a ceramidase mixture and a pharmaceutically acceptable carrier, where the ceramidase...
US-9,937,245 Highly pure neurotoxic component of a botulinum toxin, process for preparing same, and uses thereof
The present invention relates to a process for preparing a highly pure neurotoxic component of a botulinum toxin by cultivating clostridium botulinum under...
US-9,937,244 Stabilized liquid and lyophilized ADAMTS13 formulations
The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized...
US-9,937,243 Sialylated glycoprotein compositions and uses thereof
The present application relates to sialylated glycoprotein compositions and methods of their use in treating various conditions and disorders.
US-9,937,242 Compositions and methods for inhibiting the activity of LAR family phosphatases
A method of inhibiting and/or reducing the activity, signaling, and/or function of leukocyte-common antigen related (LAR) family of phosphatases in a cell of a...
US-9,937,241 Degradation resistant HSP70 formulations and uses thereof
The present invention relates to novel therapies that utilize stabilized exogenous HSP70 for the treatment of disorders or conditions regulated by HSP70 through...
US-9,937,240 Peptide having fibrosis inhibitory activity and composition containing same
The present invention relates to a composition for inhibiting fibrosis and more specifically, to a composition for inhibiting fibrosis, wherein the composition...
US-9,937,239 Preservation and reconstitution of cell-free protein expression systems
A method of preserving a cell-free protein expression system includes preserving a cell extract with a first non-reducing sugar alcohol to provide a preserved...
US-9,937,235 Lipidated peptides as anti-obesity agents
Lipidated peptides, analogs of both forms of the prolactin-releasing peptide, PrRP31 and PrRP20, represent anorexigenic compounds that lower food intake and...
US-9,937,234 Compositions and methods for using and identifying antimicrobial agents
As disclosed herein methods are provided to identify compounds with antimicrobial activity, and methods for treating subjects by administering the compounds. In...
US-9,937,233 Engineered nucleic acids and methods of use thereof
Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such...
US-9,937,232 Particles containing a growth factor, and uses thereof
The present invention concerns particles containing at least one covalently cross-linked polysaccharide and at least one growth factor, a method of preparation,...
US-9,937,231 Methods and agents for treating Alzheimer's disease
The present disclosure provides compositions and methods useful for treating or preventing diseases or disorders where beta amyloid accumulation or aggregation...
US-9,937,230 Ophthalmic uses of toxin-based therapeutic peptides and pharmaceutical compositions thereof
Disclosed herein are methods of treating ophthalmic conditions such as dry eye and uveitis by administering a pharmaceutical composition including a toxin-based...
US-9,937,229 Methods of treatment using hemopexin compositions
The present invention relates generally to a method of purifying proteins. More specifically, the present inventions relates to a method of purifying...
US-9,937,228 Treatment of myocardial infarction by inhibiting the action of mAKAP.beta.
The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective...
US-9,937,227 Humanin, analogs and cancer treatment methods and uses thereof
Described herein are methods of enhancing chemotherapeutic treatment of a hyperproliferative disorder by, in part, administering a composition comprising one or...
US-9,937,226 Use of immunomodulatory protein from ganoderma in inhibiting cancer stem cells
The present invention relates to a new use of an immunomodulatory protein derived from Ganoderma or a recombinant or a composition thereof in inhibiting cancel...
US-9,937,225 Topical formulations and uses thereof
Provided herein include formulations for topical administration, such as ophthalmic formulations, and methods of using such formulations. In some aspects and...
US-9,937,224 Modulation of axon degeneration
The invention relates generally to treatment of neurological disorders and nervous system injuries. The invention specifically provides methods of using...
US-9,937,223 Vasopressin formulations for use in treatment of hypotension
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time at...
US-9,937,221 Systems and methods for delivery of peptides
The present invention generally relates to compositions and methods for topical or transdermal delivery. The compositions can be used in a variety of...
US-9,937,220 Anti-diabetic nutraceutical composition from palm leaf extract
A comestible composition with anti-diabetic property which is effective in lowering the blood glucose and help reduce oxidative stress in diabetics and have...
US-9,937,219 Purified cannabinoid product and system and method for producing the same
A purified lipid-based solution including cannabinoids is manufactured by providing a lipid solution including an array of triglycerides, cannabinoids and water...
US-9,937,218 Systems and methods for cannabinoid and terpene extraction and purification
A method for preparing a purified cannabis extract may comprise extracting a crude extract from cannabis solids, dewatering the crude extract, removing...
US-9,937,217 Method of inhibiting ABCG2 and related treatments
Disclosed are methods of enhancing the chemotherapeutic treatment of tumor cells, reducing resistance of a cancer cell to a chemotherapeutic agent, a method of...
US-9,937,216 Method for suppressing proliferation and/or inducing apoptosis of cancer cells
It is to provide an agent for suppressing proliferation and/or inducing apoptosis of cancer cells that can be used for the treatment and chemoprophylaxis of...
US-9,937,215 Preparations with rosehip extracts, and method of producing rosehip extracts
Composition comprising an anti-inflammatory plant extract from rosehips together with a cartilage-protective substance, and a method of producing the rosehip...
US-9,937,214 Lactobacillus crispatus and application thereof
The present invention discloses Lactobacillus crispatus 262-1 and an inoculum comprising such strain and application thereof. The Lactobacillus crispatus 262-1...
US-9,937,213 Composition comprising L. rhamnosus GG
The present finding relates to a composition comprising the probiotic Lactobacillus rhamnosus GG (ATCC 53103) for use in the prevention and/or treatment of...
US-9,937,212 L. johnsonii LA1, B. longum NCC2705 and immune disorders
The present invention generally relates to the field of probiotics, and in particular to preventing and/or treating inflammatory and infectious disorders, for...
US-9,937,211 Composition of Roseburia hominis
A first aspect of the invention relates to the bacterial species Roseburia hominis for use in: regulating the immune system of a subject treating an immune...
US-9,937,210 Method for isolating fraction having anti-inflammatory or osteoarthritis-inhibiting effects by using oyster...
The present invention relates to a method for isolating a fraction having anti-inflammatory or osteoarthritis-inhibiting effects by removing impurities and...
US-9,937,209 Glycosaminoglycan compositions in combination with stem cells
A pharmaceutical preparation for treating connective tissue damage in man and in animals, comprising a therapeutically effective amount of a glycosaminoglycan...
US-9,937,208 Modulation of splenocytes in cell therapy
The invention provides methods for treating pathological conditions associated with an undesirable inflammatory component. The invention is generally directed...
US-9,937,207 Targeted disruption of T cell receptor genes using talens
Disclosed herein are methods and compositions for modifying TCR genes, using nucleases (zinc finger nucleases or TAL nucleases) to modify TCR genes.
US-9,937,206 Compositions and methods of treating T cell mediated disorder
A method of generating a CD4.sup.+FoxP3.sup.+ Treg cell, the method includes administering at least one complement antagonist to a naive CD4.sup.+ T cell at an...
US-9,937,205 Inhibition of diacylglycerol kinase to augment adoptive T cell transfer
The present invention provides compositions and methods for inhibiting one or more diacylglycerol kinase (DGK) isoform in a cell in order to enhance the...
US-9,937,204 Method and composition for prevention and treatment of oral fungal infections
A composition of stabilized chlorine dioxide at a concentration range of about 0.0004% to about 0.8% (w/v) having anti fungal properties to prevent oral fungal...
US-9,937,202 Topical nitric oxide systems and methods of use thereof
The present invention generally relates to compositions and methods for transdermal drug delivery. The compositions can be used in a variety of applications,...
US-9,937,201 Polymeric treatment compositions
Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the...
US-9,937,200 Skin compositions and methods of use thereof
Compositions and methods useful for delivering an agent to a subject are described. The methods include applying to the subject's skin a composition comprising...
US-9,937,199 Materials and methods for preventing and treating anastomotic leaks
Materials and methods for preventing and treating anastomotic leaks are disclosed. Data establishes that pathogenic microbes interfere with establishing...
US-9,937,198 Multi-functional composition and preparation method and application thereof
A multi-functional composition is disclosed as well as the preparation method and applications thereof. The composition contains a marine algae-derived material...
US-9,937,197 Wound healing compositions and treatments
This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly...
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