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Patent # Description
US-9,937,196 Genomic sequence of avian paramyxovirus type 2 and uses thereof
In this application is described the complete genomic sequence of avian parmyxovirus type 2, strains Yucaipa, England, Kenya and Bangor. The sequences are...
US-9,937,195 Edible energy composition
The disclosure relates to an edible energy composition that includes a methylated xanthine, a choline derivative and a flavorant.
US-9,937,194 Compounds and methods for treating inflammatory diseases
Described herein are compounds and pharmaceutical compositions useful for treating inflammatory diseases.
US-9,937,193 Method for treating a cancer
The present invention relates to a method for treating a cancer with the combination of a topoisomerase II inhibitor (TOP2 inhibitor) and a histone...
US-9,937,192 Combination therapy to treat mycobacterium diseases
The present invention relates to a compound of formula (I) ##STR00001## or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein....
US-9,937,191 Inhibition of HIV infection through chemoprophylaxis
A process is provided for protecting a primate host from a self-replicating infection by an immunodeficiency retrovirus. Protection is achieved by administering...
US-9,937,190 Use of aminosalicylates in diarrhoea-predominent irritable bowel syndrome
A method for the treatment or prophylaxis of non-inflammatory bowel diseases, diarrhea-predominant irritable bowel syndrome or other non-specific bowel disorder...
US-9,937,189 Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
The present invention relates to a stable fixed dose aqueous pharmaceutical composition (e.g., contained in a container) for nasal administration to a human,...
US-9,937,188 Non-irritating testosterone emulsions
Disclosed herein are emulsions comprising testosterone or related androgens, castor oil, cyclodextrin, Pemulen TR-2, Polyoxyl 40, and other ingredients. The...
US-9,937,187 Platinum compounds, compositions, and uses thereof
The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex...
US-9,937,186 Sulfonamides derived from tricyclyl-2-aminocycloalkanols as anticancer agents
A genus of arylsulfonamide derivatives of aminocycloalkanols is disclosed. The compounds are of the following genus: ##STR00001## The compounds induce FOXO1...
US-9,937,185 Imidazopyridine compounds and uses thereof
This invention generally relates to substituted imidazopyridine compounds, particularly substituted 4-(imidazo[1,2-a]pyridin-2-yl)benzamide compounds and salts...
US-9,937,184 Theobromine compositions useful for increasing fetal weight gain and enhancing bone properties
Compositions and methods for culturing cells with theobromine are provided, as well as cells derived thereby. Theobromine compositions for enhancing bone...
US-9,937,183 Antimicrobial compounds and methods of making and using the same
Methods and compounds for treating, preventing, reducing the risk of and/or delaying the onset of a microbial infection in a subject are disclosed herein,...
US-9,937,182 Therapeutic strategies for the treatment of preeclampsia
Compositions and methods for treating preeclampsia in a subject in need thereof are disclosed.
US-9,937,181 Tofacitinib oral sustained release dosage forms
The present invention relates to oral sustained release formulations of tofacitinib and pharmaceutical acceptable salts thereof. The formulations described...
US-9,937,180 Constrained tricyclic sulfonamides
Tricyclic chemical modulators of protein phosphatase 2A are disclosed. The compounds are useful to treat cancer, age-onset proteotoxicity, stress-induced...
US-9,937,179 Combined treatment for cancer resistant to an epidermal growth factor receptor kinase inhibitor
The present invention provides a method for treating a cancer, comprising (a) identifying a patient with acquired resistance to an EGFR kinase inhibitor; and...
US-9,937,178 Methods of identifying and using MDM2 inhibitors
Methods of treating subjects with cancer and screening for MDM2 inhibitors that may be effective cancer therapeutics are provided herein. The cancers that may...
US-9,937,177 Therapeutic compounds
The invention provides a compound of formula I: ##STR00001## wherein X, Y, Z have any of the values defined in the specification or a salt thereof. The...
US-9,937,176 Pyrazolothiazole compound and medicine comprising same
The invention provides a pyrazolothiazole compound of the formula [I], or a pharmaceutically acceptable salt thereof: ##STR00001## The compound of the...
US-9,937,175 Phenyloxadiazole derivatives as PGDS inhibitors
This invention is directed to a compound of formula (I): ##STR00001## wherein R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising the...
US-9,937,174 Combinations of histone deacetylase inhibitors and bendamustine
The invention relates to pharmaceutical combinations comprising an HDAC inhibitor and bendamustine; pharmaceutical compositions comprising the same; and methods...
US-9,937,173 Method of treating obesity
A method of treating obesity and obesity-related disorders in a mammal is provided. The method comprises the step of administering to the mammal a compound that...
US-9,937,172 Mixtures of heteropolycycles
A mixture of heteropolycycles has preferably two particular heteropolycycles and more preferably, no more than 10 wt. %, 5 wt. %, 2.5 wt. %, 1 wt. %, 0.5 wt. %,...
US-9,937,171 Methods of blocking the CXCR-4/SDF-1 signaling pathway with inhibitors of bruton's tyrosine kinase
In some embodiments, the present invention relates to novel small molecule inhibitors that block the CXCR4-SDF-1 signaling pathway by directly inhibiting...
US-9,937,170 Treatment of cancer with TOR kinase inhibitors
Provided herein are methods for treating or preventing a solid tumor, non-Hodgkin lymphoma or multiple myeloma in a patient, comprising administering an...
US-9,937,169 Methods for treating cancer using dihydropyrazino-pyrazine compound combination therapy
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound and an...
US-9,937,168 Nicotine-containing pharmaceutical compositions
A composition intended to be employed for therapeutic purposes incorporates nicotine and at least one other nicotinic compound. Representative forms of nicotine...
US-9,937,167 SHIP1 modulators and methods related thereto
Compounds of formula (I): ##STR00001## where ##STR00002## n, R.sup.1, R.sup.4a, R.sup.4b, R.sup.5, R.sup.7 and R.sup.8 are defined herein, or ...
US-9,937,166 Use of levocetirizine and montelukast in the treatment of traumatic injury
The embodiments described herein include methods and formulations for treating lung and brain injury. The methods and formulations include, but are not limited...
US-9,937,165 Pharmacological chaperones for treating obesity
The invention relates to methods of enhancing normal melanocortin-4 receptor (MC4R) activity, and to enhancing activity of an MC4R having a mutation which...
US-9,937,164 Opioid formulations
A depot precursor formulation comprising: a) a controlled-release matrix; b) at least oxygen containing organic solvent; c) at least 12% by weigh of at least...
US-9,937,163 Remedy for psychoneurotic diseases
A medicinal preparation for preventing and/or treating psychoneurotic diseases such as integration dysfunction and Alzheimer's disease which contains...
US-9,937,162 Methods of treating and preventing vascular instability diseases
Methods are provided of treating and preventing stroke diseases, such as cerebral cavernous malformation, by the administration of tempol and/or cholecalciferol.
US-9,937,161 Combinatorial compositions and methods for treatment of melanoma
Embodiments described here are combinatorial compositions and methods using these compositions for treating melanomas having activated mutations. The...
US-9,937,160 Thienopyridine derivative for the treatment of hepatitis C infections
The present invention relates to methods of treatment of hepatitis C using prasugrel. The methods of the present invention can be used in patients with...
US-9,937,159 Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
Embodiments of the present invention provide a method for treatment of respiratory disorders such as asthma, chronic obstructive pulmonary disease, and chronic...
US-9,937,158 Benzoheterocyclic compounds and use thereof
Disclosed are compound of formula (I) and pharmaceutically accepted salts and prodrugs thereof, wherein each of R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5,...
US-9,937,157 Modified release dosage forms of xanthine oxidoreductase inhibitor or xanthine oxidase inhibitors
The present disclosure relates to novel dosage forms of xanthine oxidoreductase inhibitors.
US-9,937,156 Modulation of MRTF-A activity in pathologic fibrosis and wound healing
The present disclosure concerns uses for isoxazole compounds or salts or analogs thereof for the treatment of wounds. The present disclosure also concerns...
US-9,937,155 Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors
The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme...
US-9,937,154 Use of telmisartan to prevent and treat graft versus host disease and other alloimmune and autoimmune diseases
The described invention relates to methods for preventing or treating graft-versus-host disease while preserving a graft-versus-tumor effect, increasing...
US-9,937,153 Oral pharmaceutical formulation of omarigliptin
The present invention is directed to stable, oral pharmaceutical formulations of dipeptidyl peptidase-4 inhibitors, such as omarigliptin. Such pharmaceutical...
US-9,937,152 Derivative of styrene-maleic acid copolymer
The present invention provides a group of novel SMA derivatives and a covalent conjugate of the derivatives and an active substance. More specifically, the...
US-9,937,151 Carbapenem antibacterials with gram-negative activity
The present invention provides .beta.-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods...
US-9,937,150 Method for enhancing the oxygenation level of tissue cells as an alternative method for hyperbaric oxygen therapy
The present invention relates to a method for substituting for or acting with the hyperbaric oxygen therapy to improve hypoxia, comprising the step of:...
US-9,937,148 Suspension compositions of physiologically active phenolic compounds and methods of making and using the same
The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular...
US-9,937,147 Edible base product composition
A composition of an edible base product, the composition comprising a cannabis concentrate containing at least one cannabinoid, a starch concentrate containing...
US-9,937,146 Enkephalin-influencing composition and method
A composition which includes Phenylalanine, Serine, Glutamine and GABA (.gamma.-aminobutyric acid). The composition contains the essential amino acids...
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