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Patent # Description
US-9,949,973 Acoustic mixing for auto granulation
A process for acoustically mixing a bulk drug substance involves the application of acoustic energy to drive an accelerative force in a mixing vessel containing...
US-9,949,972 Combinations of histone deacetylase inhibitors and immunomodulatory drugs
The invention relates to combinations comprising an HDAC inhibitor and an immunomodulatory drug for the treatment of lymphoma in a subject in need thereof. Also...
US-9,949,971 Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor and/or a JAK-2 inhibitor
Therapeutic combinations of a Janus kinase-2 (JAK-2) inhibitor, a Bruton's tyrosine kinase (BTK) inhibitor, and/or a phosphoinositide 3-kinase (PI3K) inhibitor,...
US-9,949,970 Synthesis of new benzothiazole derivatives as potential anti-tubercular agents
Disclosed are compounds of general formula A useful as potential anti-tubercular agents. The general formula A is ##STR00001##
US-9,949,969 Treatment of vasomotor symptoms
The invention relates to a method for the treatment of vasomotor symptoms comprising the administration of a therapeutically effective amount of flibanserin.
US-9,949,968 Diarylalkylamine REV-ERB antagonists and their use as medicaments
The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: ##STR00001## It further discloses a...
US-9,949,967 Temozolomide powder formulation
The present invention relates to a solid pharmaceutical composition of temozolomide that has good and consistent flowability as a powder and taste masking and...
US-9,949,966 Dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection
The invention provides novel compounds having the general formula: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are as...
US-9,949,965 Tricyclic indole Mcl-1 inhibitors and uses thereof
The present invention provides for compounds that inhibit the activity of an anti-apoptotic Bcl-2 family member Myeloid cell leukemia-1 (Mcl-1) protein. The...
US-9,949,964 Tesofensine compositions
The present invention relates to tesofensine compositions, methods to prepare the same and uses thereof in preparing medicines for the prevention and treatment...
US-9,949,963 Crystalline forms of an 8-azabicyclo[3.2.1]octane compound
The invention provides a crystalline sulfate salt of 3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-- ...
US-9,949,962 Pharmaceutical composition comprising glutarimide derivatives and use thereof in the treatment of eosinophilic...
The present invention relates to novel biologically active glutarimide derivatives of general formula (I) or a pharmaceutically acceptable salt thereof, their...
US-9,949,961 Agent for the prophylaxis and/or treatment of neoplastic diseases
The invention relates to a novel agent in the form of rhodanine derivatives, which has prophylactic, antiproliferative and antimetastatic activity. Said agent...
US-9,949,960 Pharmaceutical composition for preventing or treating muscle weakness-related diseases, containing...
The present invention relates to A method for promoting the differentiation of myoblasts comprising treating myoblasts with butylpyridinium, a derivative...
US-9,949,959 Semi-solid topical composition containing pirfenidone and modified diallyl disulfide oxide (M-DDO) for...
The instant invention relates to a semi-solid topical composition containing Pirfenidone and an antimicrobial/antiseptic agent such as Modified Diallyl...
US-9,949,957 Macrolide particulates, methods for preparation, and medical devices associated therewith
The disclosure provides macrolide particulates including a macrolide therapeutic agent such as rapamycin at high concentration in the particulate. In one method...
US-9,949,956 Compounds, compositions, and methods for preventing metastasis of cancer cells
Disclosed are methods for preventing metastasis of cancer cells. The disclosed compounds can be used to prevent the spread of tumor or other types of cancer cells.
US-9,949,955 Triazolone compounds as mPGES-1 inhibitors
The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are...
US-9,949,954 Angiotensin II receptor antagonist for the prevention or treatment of systemic diseases in cats
A method is described for the treatment of systemic diseases in cats. A composition is administered to a cat, where the composition includes a therapeutically...
US-9,949,953 Topical compositions comprising fipronil and permethrin and methods of use
The subject matter disclosed herein is directed to stable, highly-effective topical formulations comprising permethrin, fipronil and a solvent system that is...
US-9,949,952 Methods and compositions for transdermal delivery
One aspect of the invention relates to AI-helper compositions comprising an AI compound (e.g., melatonin) and one or more helper esters. The AI-helper...
US-9,949,951 Pyrrolidine-2, 5-dione derivatives, pharmaceutical compositions and methods for use as IDO1 inhibitors
Uses of compound of Formula I: ##STR00001## or pharmaceutically acceptable enantiomers, salts, solvates or prodrugs thereof are described. The compounds of...
US-9,949,950 Compositions and methods for controlled localized delivery of bone forming therapeutic agents
The present invention provides compositions and methods for providing controllable local delivery of a therapeutic agent to promote bone formation. In certain...
US-9,949,949 Macrocyclic ghrelin receptor modulators and methods of using the same
The present invention provides novel conformationally-defined macrocyclic compounds that can function as selective modulators of the ghrelin receptor (growth...
US-9,949,948 Artemisinin and its derivatives for use in the treatment of trauma haemorrhage and associated conditions
The present invention relates to the treatment of trauma haemorrhage or trauma haemorrhage-induced organ injury and associated disorders (in particular stoke,...
US-9,949,947 Delphinidin for combating melanoma cells
The invention relates to a composition comprising a complex of delphinidin and a sulfoalkyl ether-.beta.-cyclodextrin for use in the treatment of malignant...
US-9,949,946 Inclusion complexes of pinocembrin with cyclodextrin or its derivatives
Inclusion complexes of pinocembrin with cyclodextrin or its derivatives and their preparation are provided. The inclusion complexes can be used to make drugs.
US-9,949,945 3' equatorial-fluorine-substituted neuraminidase inhibitor compounds, compositions and methods for the use...
Equatorial 2,3-fluorinated glycosides compounds of formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza, the...
US-9,949,944 Drug eluting expandable devices
The present disclosure relates to drug eluting devices, and their uses. The drug eluting devices can allow for perfusion during deployment. The coatings the may...
US-9,949,943 Method for treating neurodegenerative diseases
A method for treating neurodegenerative diseases including the step of administering an isothiocyanate functional surfactant to an area affected by a...
US-9,949,942 Sustained release delivery of active agents to treat glaucoma and ocular hypertension
The methods described herein provide treatment of glaucoma, ocular hypertension, and elevated intraocular pressure with latanoprost or other therapeutic...
US-9,949,941 GABA analog prodrug sustained release oral dosage forms
Sustained release oral dosage forms of a gabapentin prodrug, 1-{[(.alpha.-isobutanoyloxyethoxy)carbonyl]aminomethyl}-1-cyclohexane acetic acid, are disclosed....
US-9,949,940 Pharmaceutical compositions containing dexketoprofen and tramadol
A pharmaceutical composition as a solid oral dosage form is described, comprising: i) a combination of two pharmacological active principles, dexketoprofen...
US-9,949,939 Systems and methods for treating vitiligo
The present invention generally relates to systems and methods for treating vitiligo. In one set of embodiments, the present invention comprises a composition...
US-9,949,938 CoQ10 (ubiquinone, ubiquinol), vitamin A (retinoid acid, retinol), vitamin E (tocotrienol, tocopherol) and...
CoQ10 and vitamin E are both lipid-soluble nutrients with redox potential. Tocopherol and/or tocotrienol protect CoQ10 from oxidative damage and reduce...
US-9,949,937 Use of cannabinoids in the treatment of epilepsy
The present disclosure relates to the use of cannabidiol (CBD) for the reduction of total convulsive seizure frequency in the treatment of "treatment-resistant...
US-9,949,936 Use of cannabinoids in the treatment of epilepsy
The present disclosure relates to the use of cannabidiol (CBD) for the reduction of total convulsive seizure frequency in the treatment of "treatment-resistant...
US-9,949,935 Rivastigmine transdermal compositions and methods of using the same
Rivastigmine transdermal compositions are provided. Aspects of the transdermal compositions include an active agent layer which includes rivastigmine and a...
US-9,949,934 Device and method of treating conditions associated with neuroinflammation
Disclosed is a device and method for treating a neurodegenerative disease or condition associated with neuroinflammation induced by a leukotriene. The device is...
US-9,949,933 Fenofibrate formulation
Various fenofibrate dosage forms contain a plurality of beads or particles, where the beads or particles include a pharmaceutical composition comprising...
US-9,949,932 Formulation of syk inhibitors
Disclosed are pharmaceutical compositions comprising a compound having the formula: ##STR00001## or a pharmaceutically acceptable salt thereof, or a hydrate...
US-9,949,931 Methods of treating attention deficit hyperactivity disorder
The invention is directed to oral modified/controlled release drug formulations which provide a rapid initial onset of effect and a prolonged duration of...
US-9,949,930 Opioid agonist formulations with releasable and sequestered antagonist
Disclosed are oral dosage forms, comprising (i) a therapeutically effective amount of an opioid agonist; (ii) an opioid antagonist in releasable form; and (iii)...
US-9,949,929 Drug carrier and manufacturing method thereof
A drug carrier and a manufacturing method thereof are provided. The drug carrier includes a hydrophilic group, a hydrophobic group and an organic dye. The...
US-9,949,928 Biodegradable copolymers, systems including the copolymers, and methods of forming and using same
Therapeutic agent delivery systems, which include a thermally-sensitive copolymer and optionally a therapeutic agent, are disclosed. The copolymer is water...
US-9,949,927 Bis-polymer lipid-peptide conjugates and nanoparticles thereof
The present invention provides bis-polymer lipid-peptide conjugates containing a hydrophobic block and headgroup containing a helical peptide and two polymer...
US-9,949,926 Eye drop with difluprednate for macular edema treatment
The present invention aims to provide an eye drop for treating macular edema. The present invention provides an eye drop for treating macular edema, which...
US-9,949,925 Bactericidal compositions and methods for treating pathogenic biofilms
Disclosed herein are bactericidal compositions that are effective against pathogenic biofilms, especially against biofilms formed by Pseudomonas aeruginosa. The...
US-9,949,924 Methods and compositions for oral administration of protein and peptide therapeutic agents
The present invention provides a pharmaceutical composition formulated for oral delivery, comprising a particulate non-covalently associated mixture of...
US-9,949,923 Nasal delivery
A nasal delivery device for and method of delivering a substance, preferably comprising oxytocin, non-peptide agonists thereof and antagonists thereof,...
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