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Patent # Description
US-9,962,378 ROS1 inhibitor and its use
The administration of a compound advantageously efficacious as ROS1 inhibitor and its effect on subjects with cancer includes administering a compound having...
US-9,962,377 Hydroxy-6-heteroarylphenanthridines and their use as PDE4 inhibitors
Compounds of the formula Ia***** ##STR00001## in which the substituents have the definitions provided in the specification, are novel, effective PDE4...
US-9,962,376 Methods and ophthalmic devices used in the treatment of ocular allergies
Ophthalmic devices and methods of treating allergic conjunctivitis are disclosed herein.
US-9,962,375 Methyl-piperidine compounds useful for inhibiting microsomal prostaglandin E.sub.2 synthase-1
The present invention provides compounds of Formula (1), or a pharmaceutically acceptable salt thereof, formula (1), where R, R1, and G are as described herein;...
US-9,962,374 Process for the preparation of a pharmaceutical composition containing pirfenidone in sustained-release tablet...
The instant invention relates to a process for the preparation of a pharmaceutical composition in sustained-release tablet form comprising from 600 milligrams...
US-9,962,373 Methods of treating bladder cancer
The present invention provides methods and compositions for treating bladder cancer, including metastatic bladder cancer and non-muscle-invasive bladder cancer,...
US-9,962,372 Pharmaceutical composition for the treatment of mycosis
The present invention relates to a pharmaceutical composition comprising a combination of benzydamine and an antimycotic active ingredient, said combination...
US-9,962,371 Ready to use ketorolac formulations
Disclosed in certain embodiments is a pharmaceutical composition for parenteral administration comprising: an aqueous solution comprising ketorolac or a...
US-9,962,370 Methods of treatment associated with the granulocyte colony-stimulating factor receptor
Some embodiments include methods for treating, preventing, reversing, halting, or slowing the progression of cancer, comprising administering to a subject in...
US-9,962,369 Methods and compositions for transdermal delivery
One aspect of the invention relates to AI-helper compositions comprising an AI compound (e.g., melatonin, alpha-lipoic acid, vitamin E, vitamin D, glutathione,...
US-9,962,368 Pro-neurogenic compounds
This technology relates generally to compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and...
US-9,962,367 Oral formulations of pyrrolidine derivatives
The present invention relates to solid oral formulations comprising a compound of formula ...
US-9,962,366 Enhancing autophagy or increasing longevity by administration of urolithins or precursors thereof
Disclosed are methods, compounds, and compositions useful for increasing autophagy and promoting longevity. The methods, compounds, and compositions relate to...
US-9,962,365 Compositions and methods for preventing and recovery from detrimental effects of alcohol consumption
Disclosed are compositions, devices, and methods to prevent and recover from detrimental effects of alcohol consumption, including significant undesirable...
US-9,962,364 Wound healing accelerator
The purpose of the present invention is to provide a specific wound healing accelerator effective for accelerating healing of wounds, particularly of wounds in...
US-9,962,363 Mast cell stabilizers treatment for systemic disorders
Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders, are provided.
US-9,962,362 Use of small molecule inhibitors targeting EYA tyrosine phosphatase
Inhibitors of EYA tyrosine phosphatase are provided herein, as well as pharmaceutical compositions and methods relating thereto.
US-9,962,361 Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use
An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: ##STR00001## ...
US-9,962,360 Compositions and methods for enhancing hair growth, promoting skin regeneration, and wound healing
The invention relates to compositions and methods useful for enhancing hair growth and promoting skin regeneration. Particularly, the invention provides topical...
US-9,962,359 Methods of therapeutic monitoring of nitrogen scavenging drugs
The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that...
US-9,962,358 Methods of therapeutic monitoring of nitrogen scavenging drugs
The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that...
US-9,962,357 Halogenated esters of cyclopropanated unsaturated fatty acids for use in the treatment of neurodegenerative...
The present disclosure describes novel PKC- activators chosen from halogenated esters of unsaturated fatty acids derivatives thereof, including halogenated...
US-9,962,356 Method of treating obesity with chlorogenic acid
The present invention is directed compositions derived from green coffee bean extract and methods for the use and manufacture of such compositions. The...
US-9,962,355 Mixture of fatty acids and palmitoylethanolamide for use in the treatment of inflammatory and allergic pathologies
The present invention relates to a mixture containing up to two fatty acids selected from palmitic acid, oleic acid, stearic acid, linoleic acid,...
US-9,962,354 Method and composition for bacterial or fungal suppression on skin
The present disclosure relates to methods and compositions for suppressing the growth of microorganisms on selected areas of the skin for an extended period of...
US-9,962,353 Use of tall oil fatty acid in binding toxins
The present invention relates to use of a tall oil fatty acid and/or a tall oil fatty acid which is modified by saponification in binding toxins.
US-9,962,352 Creatine oral supplementation using creatine hydrochloride salt
The present invention is directed to an oral supplement including creatine hydrochloride, which has an aqueous solubility that is at least 15 times greater than...
US-9,962,351 Small molecule substance for improving sensitivity of bacteria to antibiotics
Disclosed is a new function of a small molecule metabolite glutamine. The small molecule can improve sensitivity of bacteria including antibiotic-resistant...
US-9,962,350 Agent for improving normal development rate of fertilized eggs
It is intended to provide an in vitro culture medium that allows the in vitro culture of fertilized eggs to progress normally to the blastocyst stage without...
US-9,962,349 Dermal therapeutic system with high adhesivity
The present invention relates to a high adhesion dermal therapeutic system comprising an adhesive polymeric matrix with a salt of Diclofenac.
US-9,962,348 Treatment and diagnosis of melanoma
The present invention discloses novel agents and methods for diagnosis and treatment of melanoma. Also disclosed are related arrays, kits, and screening methods.
US-9,962,347 Broad spectrum pharmacological composition for treatment of various infections and diseases and methods of use
A pharmacological composition for the treatment of bacterial and protozoal infections in a patient. The preferred pharmacological composition comprises a...
US-9,962,346 Treatment of NAFLD and NASH
Treatment of NAFLD and NASH by therapy with MBX-8025 or an MBX-8025 salt.
US-9,962,345 Oral liquid compositions of guanfacine
The present invention relates to oral liquid compositions of guanfacine. The liquid compositions can be immediate release or extended release compositions. The...
US-9,962,344 Chemosensory receptor ligand-based therapies
Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases,...
US-9,962,343 Intravenous administration of tramadol
A method of treating pain, e.g., acute post-operative pain, by administering to a human patient(s) a therapeutically effective dose of tramadol intravenously...
US-9,962,342 Pharmaceutical composition containing guaifenesin and application thereof
The present invention provides a pharmaceutical composition containing Guaifenesin. The invention pharmaceutical composition comprises a core containing...
US-9,962,341 Active pharmaceutical ingredient (API) comprising cannabinoids for use in the treatment of cancer
The present invention relates to an active pharmaceutical ingredient (API) which comprises or consists essentially of cannabidiol (CBD) and one other...
US-9,962,340 Device and method for the transdermal delivery of cannabidiol
Transdermal delivery devices for the delivery of cannabidiol (CBD) are shown and described. In a reservoir-patch design, a microporous, hydrophilic membrane and...
US-9,962,339 Stabilized assembled nanostructures for delivery of encapsulated agents
A non-covalently assembled hydrogel or organo-gel composition with serum stability is described. Low molecular weight (<2,500 Da), generally regarded as safe...
US-9,962,338 Method of making particles for use in a pharmaceutical composition
The invention relates to a method for making composite active particles for use in a pharmaceutical composition for pulmonary administration, the method...
US-9,962,337 Process for forming a substance with a superstructure and application thereof
The present invention provides a process for forming a substance with a superstructure and a process for forming Janus particles. The novel application of the...
US-9,962,336 Extended release suspension compositions
The present invention relates to a method for preparing a stable extended release suspension composition comprising multiple coated cores of an active...
US-9,962,335 Method of manufacturing enteric soft capsule
An object is to provide a method of manufacturing a soft capsule that is enteric and excellent in formulation properties. An enteric soft capsule is...
US-9,962,334 Ophthalmic device having therapeutic agent delivery capability and method of forming same
The present invention is directed to ophthalmic devices that are loaded with therapeutic agent. The devices provide prolonged release of the therapeutic agent...
US-9,962,333 Timed release of substances to treat ocular disorders
A system is disclosed for simple, non-invasive, sustained delivery of ophthalmic substances to the interior of the eye, for the prevention and treatment of eye...
US-9,962,332 Method for preventing nasolacrimal duct obstruction
The invention is directed to a method for preventing nasolacrimal duct obstruction (NLDO) in a patient receiving high dose radioactive iodine for treatment of...
US-9,962,331 Composition containing horse chestnut extract
The present invention relates to a composition containing Horse chestnut extract that inhibits angiogenesis and matrix metalloproteinase activity. The Horse...
US-9,962,330 Compositions and methods for the maintenance of oral health
The disclosure provides compositions comprising one or more isolated LDH-deficient mutans streptococcus strains and one or more isolated S. oxalis strains...
US-9,962,328 Nail care system
The present invention relates to a nail care system containing (1) at least one composition containing at least one adhesive agent, at least one primary film...
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