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Patent # Description
US-9,968,641 Method to suppress the systemic toxicity of chemotherapeutic drugs
This invention relates to use of manuka honey in the treatment of cancer. The invention is also directed to the combination of manuka honey with other...
US-9,968,640 Method for treating or preventing a pancreatic dysfunction
The present invention provides a method for improving pancreatic function in a subject in need thereof, the method comprising administering to the subject...
US-9,968,639 Stem cells and pancreatic cells useful for the treatment of insulin-dependent diabetes mellitus
Fresh human pancreas tissue can be used as a source of cells when to identify and select a non-stem cell population that is predisposed to be a source for...
US-9,968,638 Compositions and methods for transplantation of colon microbiota
The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or...
US-9,968,637 Dopaminergic neurons differentiated from pluripotent stem cells and uses thereof
The present invention provides populations of neural cells derived from pluripotent cells, and methods for making and using the same. Disclosed herein are...
US-9,968,636 Peritoneal dialysis fluid comprising a GSK-3 inhibitor
The present invention relates to a peritoneal dialysis fluid comprising a compound inhibiting glycogen synthase kinase (GSK)-3 activity, in particular...
US-9,968,635 Treatment of skin and soft tissue infection with nitric oxide
The present invention generally relates to compositions and methods for treatment of skin and/or other soft tissues that are infected with bacteria such as...
US-9,968,634 Techniques and systems for treatment of neuropathic pain and other indications
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of neuropathic pain or other conditions. In some...
US-9,968,633 Stimuli responsive compositions for iron chelation
The present technology provides new compositions comprising at least one cross-linked co-polymer. In some embodiments, the polyacrylamide co-polymer comprises...
US-9,968,632 Fast acting joint relief formulations
The instant invention provides a method and composition for treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis,...
US-9,968,631 Method for treatment of pulmonary fibrosis
Methods and compositions of the invention relate to the treatment of pulmonary fibrosis.
US-9,968,630 Pharmaceutical combination comprising a CIP2A silencing agent for use in the treatment of a hyperproliferative...
The invention is based on a finding that silencing CIP2A (KIAA1524) gene sensitizes cancer cells for apoptosis-inducing activity of certain small molecule...
US-9,968,629 Product and method for supporting uridine homeostasis
This invention pertains to the use of an uridine source, preferably uridine monophosphate, for increasing, controlling and/or maintaining fasting plasma uridine...
US-9,968,628 Methods and compositions for treating flaviviruses and pestiviruses
A method and composition for treating a host infected with flavivirus or pestivirus comprising administering an effective flavivirus or pestivirus treatment...
US-9,968,627 Solid forms comprising 4-amino-1-.beta.-D-ribofuranosyl-1,3,5-triazin-2(1H)-one and a coformer, ...
Provided herein are solid forms comprising (a) 4-amino-1-.beta.-D-ribofuranosyl-1,3,5-triazin-2(1H)-one and (b) a coformer. Pharmaceutical compositions...
US-9,968,626 Method for treating obesity
The present invention is directed to methods for treating obesity, reducing excessive body weight, treating an obesity-related condition, treating unwanted...
US-9,968,625 Synthetic or recombinant fucosylated oligosaccarides for use in the treatment of infections
The present invention relates to synthetic fucosylated oligosaccharide for use in the treatment or prophylaxis of an infection with a Norwalk-like Virus or...
US-9,968,624 Depression treatment agent
The invention provides an agent for treating depression, which contains N-acetyl-D-mannosamine, and a pharmaceutical composition for treating depression, which...
US-9,968,623 Prepackaged sterile syringe or containers with various substance concentrations with or without bioactive reagent
A prepackaged sterile syringe or bottle with various concentrations of tissue and organ biologically stimulating reagents i.e., dextrose, various anthocyanins,...
US-9,968,622 High-purity phospholipids
Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids, are disclosed....
US-9,968,621 Parenteral compositions of celecoxib
Parenteral (injectable) celecoxib emulsions and nanoemulsions are disclosed as are their use to treat pain in patients so afflicted. The emulsions are generally...
US-9,968,620 Methods of treating lymphoma using thienotriazolodiazepine compounds
A method of treating lymphoma in a mammal comprises the step of: administering to a patient a pharmaceutical acceptable amount of a compound being a...
US-9,968,619 Method of treating triple-negative breast cancer using thienotriazolodiazepine compounds
A method of treating triple-negative breast cancer in a mammal comprising the step of: administering to a patient a pharmaceutical acceptable amount of a...
US-9,968,618 Combination therapies for the treatment of Alzheimer's disease and related disorders
The present invention relates to combination therapies for treating Alzheimer's disease or an amyloidosis-associated pathological condition comprising...
US-9,968,617 Local topical administration formulations containing indoxacarb
The present invention provides formulations and methods useful in the control of ectoparasites on a domestic animal, using a formulation comprising Indoxacarb...
US-9,968,616 Discovery of FDA-approved drugs as inhibitors of fatty acid binding protein 4 using molecular docking screening
Using molecular docking screening, a few therapeutical compounds including trovafloxacin and levofloxacin have been first identified as potential inhibitors of...
US-9,968,615 Methods for controlled proliferation of stem cells / generating inner ear hair cells using...
The present invention relates to methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to...
US-9,968,614 Aprepitant injectable formulations
An aqueous stable and ready-to-use formulation of aprepitant is prepared. Especially preferred formulations comprise a synergistic combination of a co-solvent...
US-9,968,613 Use of a ppar-delta agonist for reducing loss of muscle strength, muscle mass, or type I muscle fibers in an...
The present invention provides methods for reducing loss of muscle strength, muscle mass, or Type I muscle fibers in an immobilized limb by administering ...
US-9,968,612 Method of synthesizing thyroid hormone analogs and polymorphs thereof
The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the...
US-9,968,611 Methods and devices for renal nerve blocking
Drug eluting implants for targeted delivery of a nerve blocking agent to inhibit neural traffic along renal nerves of a human patient.
US-9,968,610 Pyrrolopyrimidine derivatives as NR2B NMDA receptor antagonists
Disclosed are chemical entities of formula I: ##STR00001## wherein X, Y, Z, R.sup.1, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are defined herein, as NR2B subtype...
US-9,968,609 Sildenafil solutions and methods of making and using same
A pharmaceutical composition comprising: (a) a liquid carrier comprising water and at least 20% of at least one alcohol; and (b) sildenafil citrate dissolved in...
US-9,968,608 Pharmaceutical compositions comprising pemetrexed and tromethamine
A pharmaceutical composition of Pemetrexed represented by formula (I), which is a liquid ready to use solution formulation or a lyophilized pharmaceutical...
US-9,968,607 Pharmaceutical compositions of raltegravir, methods of preparation and methods of use therof
Disclosed are pharmaceutical compositions comprising HIV integrase strand transfer inhibitor. More particularly, oral pharmaceutical compositions of raltegravir...
US-9,968,606 Deuterated compounds for treating cancer and related diseases and conditions, and compositions and methods thereof
The invention provides novel chemical compounds useful for treating cancer or a related disease or disorder thereof, and pharmaceutical composition and methods...
US-9,968,605 2-(2-methylamino-pyrimidin-4-yl)-1h-indole-5-carboxylic acid ...
2-(2-methylamino-pyrimidin-4-yl)-1H-indole-5-carboxylic acid [(S)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide for use in the treatment of pain...
US-9,968,604 Chromene derivatives as phoshoinositide 3-kinases inhibitors
Chromene compounds of formula (I), defined herein, inhibit phosphoinositide 3-kinases (PI3K) and are useful for the treatment of disorders associated with a...
US-9,968,603 Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
Therapeutic agent delivery formulations for the sustained release of therapeutic agents from a Port Delivery System (PDS) implant is described in this application.
US-9,968,602 Modulation of cell fates and activities by phthalazinediones
Phthalazinediones that function as intracellular redox modulators are useful in treating cells in various disease states where intracellular redox status is...
US-9,968,601 Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and...
US-9,968,600 Treatment and prognostic monitoring of non-cancerous proliferation disorders using hedgehog pathway inhibitors
The present invention concerns methods for treating a proliferation disorder, such as prostate cancer, basal cell carcinoma, lung cancer, and other cancers,...
US-9,968,599 Platinum compounds that inhibit constitutive STAT3 signaling and induce cell cycle arrest and apoptosis of...
The subject invention concerns a compound and compositions having activity as an inhibitor of Stat3 protein and methods of using the compound and compositions....
US-9,968,598 Process of making stable abuse-deterrent oral formulations
The present disclosure relates to cured pharmaceutical compositions designed to reduce the potential for improper administration of drugs that are subject to...
US-9,968,597 Methods and uses of quinoline derivatives in the treatment of soft tissue sarcomas and pharmaceutical...
The present invention addresses methods and uses of quinoline derivatives in the treatment of tumors and pharmaceutical compositions for treatment of same....
US-9,968,596 Antiproliferative compounds and methods of use thereof
Compounds of formula I for treating, preventing or managing cancer are disclosed. Also disclosed are methods of treating, preventing or managing cancer, such as...
US-9,968,595 Pharmaceutical compositions of therapeutically active compounds
Provided are compounds and pharmaceutical compositions useful for treating cancer and methods of treating cancer comprising administering to a subject in need...
US-9,968,594 Compositions and methods for the treatment of presbyopia
The invention provides compositions and methods for the treatment of presbyopia. In a preferred embodiment correction of presbyopia occurs without reduction in...
US-9,968,593 Combination therapy for treatment of resistant bacterial infections
The present invention is directed to combinations of a .beta.-lactamase inhibitor with sulbactam and, optionally, imipenem/cilastatin. The combinations are...
US-9,968,592 Dyslipidemia therapeutic agent
This invention provides a combination-drug composition and a combination use of pharmaceuticals for preventing and/or treating dyslipidemic conditions such as...
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