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Patent # Description
US-9,976,151 Artificial DNA sequence with optimized leader function in 5'(5'-UTR) for the over-expression of recombinant...
Artificial DNA of a 5'-UTR leader region, which artificial DNA is effective in increasing the expression of recombinant proteins in plants, and comprises, along...
US-9,976,150 Vector replicable in E. coli and cell of genus Komagataeibacter, cell including the same, and method of using...
Provided are a vector replicable in E. coli and a cell of the genus Komagataeibacter, a cell including the same, a method of producing a target protein using...
US-9,976,149 Modified listeria bacteria and uses thereof
A Listeria bacterium is disclosed which comprises a first mutation in the multidrug resistance transporter M (MdrM) gene which causes a decrease in ...
US-9,976,148 Yeast terminator and use therefor
A yeast terminator derived from a yeast DIT1 terminator when aligned with the nucleotide sequence represented by SEQ ID NO:1, includes a partial nucleotide...
US-9,976,147 STAT3 inhibitors and uses thereof
Described herein, inter alia, are STAT-binding nucleic acids-including compositions and methods of using the same.
US-9,976,146 Aptamer targeting MAGE-A3 peptide and uses thereof
Disclosed herein is an aptamer targeting a MHC-presented peptide and its uses thereof. The MHC-presented peptide is expressed in various cancer cells; therefor,...
US-9,976,145 Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same
The present invention is related to a method for generating a nucleic acid molecule capable of binding to a target molecule comprising the following steps: a)...
US-9,976,144 Method for controlling obesity using minimally invasive means
Methods for controlling obesity using minimally-invasive procedures including introducing embolic crystal particles that are naturally occurring and mostly...
US-9,976,143 Targeted augmentation of nuclear gene output
Provided herein are methods and compositions for increasing production of a target protein or functional RNA by a cell.
US-9,976,142 Targeting molecule and a use thereof
Provided are: a targeting molecule targeting a target cell which is selected from the group consisting of a stellate cell, a myofibroblast, a cancer-associated...
US-9,976,141 Compositions and methods for inhibiting gene expression of Hif2alpha
RNA interference (RNAi) triggers and RNAi trigger conjugates for inhibiting the expression of Hif2.alpha. (EPAS1) gene are described. Pharmaceutical...
US-9,976,140 Microrna and uses in brown fat differentiation
This invention reveals a novel miRNA and a novel miRNA-regulated signaling network which controls brown adipogenesis and thermogenic programs, thereby providing...
US-9,976,139 Recombinant DNA for gene suppression
Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by...
US-9,976,138 Methods and compounds useful in conditions related to repeat expansion
Described are compounds and methods useful for the treatment and investigation of diseases and disorders associated with expanded repeat-containing RNA molecules.
US-9,976,137 Targeted self-assembly of functionalized carbon nanotubes on tumors
Provided herein are methods for delivering a molecule in situ to a cell and for treating a cancer via the in situ delivery. The methods comprise contacting or...
US-9,976,136 Rapid methods for the extraction of nucleic acids from biological samples
The invention is directed to compositions and methods for rapidly and efficiently extracting nucleic acids and/or targeted nucleic acids sequences from...
US-9,976,135 Human trypsinogen with reduced autoactivation and its use in an immunoassay
The present invention relates to a polypeptide consisting of or comprising a variant of human trypsinogen-1, comprising the substitutions: amino acid residue...
US-9,976,134 Thermolysin variants
The present invention provides methods and compositions comprising at least one thermolysin-like neutral protease enzyme with improved storage stability and/or...
US-9,976,133 Synzymes
Novel synthetic catalytic structures or "synzymes," e.g., synthetic polypeptides, with catalytic properties are provided. It is believed that these synthetic...
US-9,976,132 Thermostable cellobiohydrolase
A thermostable cellobiohydrolase, having a cellobiohydrolase catalytic domain including: (A) a polypeptide including the amino acid sequence represented by SEQ...
US-9,976,130 OPAA FL--a mutant enzyme with increased catalytic efficiency on organophosphorus compound GD
This invention is directed toward a non-wild-type organophosphorus acid anhydrolase enzyme having two site mutations, method of production, and method of use to...
US-9,976,129 Fusion protein for protein detection, and method for detecting protein
A fusion protein for protein detection in which are fused: a protein domain including at least one among a C1 domain of protein G, a C2 domain of protein G, and...
US-9,976,128 Polymerase compositions, methods of making and using same
The present disclosure provides compositions, methods, kits, systems and apparatus that are useful for nucleic acid polymerization. In particular, modified...
US-9,976,127 Manganese superoxide dismutase variants and uses thereof
The present invention concerns variant proteins of manganese superoxide dismutase (MnSOD) and uses thereof. In particular, the invention concerns a short...
US-9,976,126 Modified glycine oxidase
The present invention provides a novel enzyme and methods of using the enzyme for measuring glycine concentration. Specifically, the present invention provides...
US-9,976,125 FAD-conjugated glucose dehydrogenase gene
An object of the present invention is to provide: a novel gene (polynucleotide) encoding an FAD-conjugated glucose dehydrogenase having excellent properties...
US-9,976,124 Hydrogenase isolated from Thermococcus spp
The present invention relates to novel hydrogenases isolated from novel hyperthermophilic strains belonging to Thermococcus spp., genes encoding the...
US-9,976,123 Cellular seeding and co-culture of a three dimensional fibroblast construct
The present invention provides methods for cellular seeding onto three-dimensional fibroblast constructs, three-dimensional fibroblast constructs seeded with...
US-9,976,122 Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptor...
Provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing an inducible pattern recognition receptor adapter,...
US-9,976,121 T cells with increased immunosuppression resistance
This invention relates to the treatment of cancer in an individual by administration of a population of modified T cells that express a recombinant cAMP...
US-9,976,120 Tubular scaffold for neural growth
A scaffold for neurons consists of tubes sized to promote neural growth through the tubes. The tubes may be fixed to a substrate providing electrical or optical...
US-9,976,119 Compositions and methods for improving the quality of processed sperm
The present invention relates to compositions and methods for the handling of processed sperm including samples that are freshly collected, those transported as...
US-9,976,118 Method for inducing tailored pluripotent stem cells using extract of plant stem cells or plant dedifferentiated...
A method for inducing tailored pluripotent stem cells by reprogramming differentiated cells of an adult by using an extract of plant stem cells and plant...
US-9,976,117 Method for cell culture
A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I.alpha.I (inter-alpha...
US-9,976,116 Programmable synthetic lysis system for controlled release of macromolecules
The present invention relates to an expression system or a recombinant cell comprising one or more nucleic acid constructs, wherein the one or more nucleic acid...
US-9,976,115 Bone marrow adipose portion isolation device and methods
The embodiments disclosed herein generally relate to systems, devices and methods for the fractionation, isolation, extraction and processing of the adipose...
US-9,976,114 Multilayer tissue cell culture vessel
The present invention discloses a vessel for culturing cells which includes: a bottom, a top, a tubular neck, and, one or more shelves. The first shelf adjoins...
US-9,976,113 Methods, apparatuses, and systems for cell and tissue culture
This invention provides an apparatus and method for culturing cells to probe the influence that the properties of a surface onto which the cells are bonded has...
US-9,976,112 Absorbent pads and methods of manufacturing
The embodiments disclosed herein relate to absorbent pads. The absorbent pads can be used as cleansing wipes, and can be used to clean various objects,...
US-9,976,111 TiN hard mask and etch residual removal
Composition, method and system for PVD TiN hard mask removal from 28/20 nm pattern wafers have been disclosed. The composition uses peroxide as oxidizing agent...
US-9,976,110 Cosmetic brush soap
A cosmetic brush cleanser having a solid goat's milk soap base and comprising almond oil, jasmine oil, coconut oil, and lavender oil.
US-9,976,109 Precursor polyelectrolyte complexes compositions
The invention relates to compositions and methods of treatment employing compositions comprising polyelectrolyte complexes. The compositions include a...
US-9,976,108 Ethanol-free microemulsion perfuming compositions
The present invention provides a perfuming composition that is free of ethanol and that is in the form of a transparent, clear microemulsion that contains a...
US-9,976,107 Enzymes and methods for producing .omega.-3 fatty acids
The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and...
US-9,976,106 Refrigerator oil composition and refrigerator system
Provided is a refrigerating machine oil composition, which is to be used for a refrigerant including a mixture of an unsaturated fluorinated hydrocarbon...
US-9,976,105 Silicone polymer emulsions
Silicone oil-in-water emulsions containing a polysiloxane containing polymer is prepared by first preparing a polysiloxane containing polymer by the...
US-9,976,104 Antiwear composition and method of lubricating driveline device
The present invention relates to an antiwear agent and lubricating compositions thereof. The invention further provides for a method of lubricating a driveline...
US-9,976,103 Lubricating composition containing an antiwear agent
The invention provides a lubricating composition containing an oil of lubricating viscosity and a nitrile compound. The invention further relates to a method of...
US-9,976,102 Composition and method of manufacturing calcium sulfonate greases using alkali metal hydroxide and delayed...
An overbased calcium sulfonate grease composition and method of manufacture comprising added alkali metal hydroxide alone or in combination with (a) calcium...
US-9,976,101 Method of manufacturing calcium sulfonate greases using delayed addition of non-aqueous converting agents
A method of manufacturing an overbased calcium sulfonate grease comprising a reduced amount of overbased calcium sulfonate, water and at least one non-aqueous...
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