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Patent # Description
US-9,974,780 Solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and a coformer, ...
Provided herein are solid forms comprising (a) 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and (b) a coformer. Pharmaceutical compositions...
US-9,974,779 Piperidine derivatives as human papilloma virus inhibitors
The present disclosure is directed to antiviral compounds directed against the papilloma virus, to pharmaceutical compositions containing them, to their...
US-9,974,778 Substituted pyridinones as MGAT2 inhibitors
The present invention provides compounds of Formula (I): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof,...
US-9,974,777 Tetrahydrocarboline derivative
An object of the present invention is to provide a drug having the inhibitory activity on ENPP2 which is a different target from that of the existing drug, as a...
US-9,974,776 Estrogen receptor beta agonists for use in treating mesothelioma
The invention provides a treatment of mesothelioma, especially malignant pleural mesothelioma, using an estrogen receptor .beta. subtype (ER.beta.) agonist,...
US-9,974,775 Substituted imidazoles as N-type calcium channel blockers
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are...
US-9,974,774 Combinatorial methods to improve the therapeutic benefit of bisantrene and analogs and derivatives thereof
The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal...
US-9,974,773 Stabilized oxymetazoline formulations and their uses
The present invention provides stabilized cream formulations of oxymetazoline and uses thereof. The present invention also provides a method of treating facial...
US-9,974,772 Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators
The present invention relates to novel amide derivatives of N-urea substituted amino acids, processes for preparing them, pharmaceutical compositions containing...
US-9,974,771 Compositions and methods for reducing prion levels
Compositions and methods for reducing the level of prions in a prion-infected cells or host by exposing prion infected cells, tissues and organs to AR-12 and...
US-9,974,770 Formulations comprising triptan compounds
The invention provides a pharmaceutical composition for intranasal administration comprising a salt of sumatriptan or a physiologically acceptable solvate...
US-9,974,769 Use of NK-1 receptor antagonist serlopitant in pruritus
The invention relates to methods for treating pruritus with NK-1 receptor antagonists such as serlopitant. The invention further relates to pharmaceutical...
US-9,974,768 Pharmaceutical for improving dysphagia
A dysphagia improving composition characterized in that a substance having an inhibitory action on an angiotensin converting enzyme, which is a degrading enzyme...
US-9,974,767 Statins in the treatment of muscular dystrophies and myopathies
The invention provides methods and compositions for treating neuromuscular diseases including, but not limited to muscular dystrophies. It is demonstrated...
US-9,974,766 Prenylated isoflavones for treatment of subjects with multidrug-resistant cancer
Prenylated isoflavones are suitable to specifically inhibit P-glycoprotein in multidrug-resistant cancer cells leading to an accumulation of cytotoxic compounds...
US-9,974,765 Transplatin derivatives as anticancer agents
The invention is directed to platinum(II) thione complexes of formula (I) and to methods of treating cancer using these complexes.
US-9,974,764 Compositions and methods of use of phorbol esters in the treatment of neoplasms
Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of chronic and acute conditions. Such...
US-9,974,763 Modulators of intracellular chloride concentration for treating neurodegenerative diseases with Parkinsonian...
A composition for treating Neurodegenerative Diseases with Parkinsonian Syndromes in a subject in need thereof, wherein the composition includes an effective...
US-9,974,762 Necrosis inhibitors
The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides,...
US-9,974,761 Medications for deposition on biological surfaces
Personal care compositions, such as oral medication compositions containing a flavor system comprising one or more coolants. The pleasant cool sensation...
US-9,974,760 Compositions and methods for treating cancer
The present invention provides, in part, compositions and methods for treating cancer using a combination of C6-ceramide and other anti-cancer agents.
US-9,974,759 Beta 2 adrenoceptor antagonists for treating orthostatic hypotension
Methods of treating orthostatic hypotension are disclosed. The methods include administering to a subject in need thereof an effective amount of a beta 2...
US-9,974,758 Sphingosine kinase type 1 inhibitors and uses thereof
Provided are inhibitors of sphingosine kinase Type I that are useful in a number of applications, indications and diseases, as well as for monitoring...
US-9,974,757 Methods for maintaining or improved health, well-being and/or a physiological function in a subject
The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition...
US-9,974,756 Composition and method to alleviate joint pain using phospholipids and astaxanthin
A dietary supplement composition and associated method of use has the composition formulated in a therapeutic amount to treat and alleviate symptoms of joint...
US-9,974,755 Induced expression of brain derived neurotrophic factor (BDNF) for treatment of neuromuscular,...
A method of treating a host of neuromuscular, neurodegenerative, developmental, autoimmune and metabolic diseases/disorders related to aging, such as traumatic...
US-9,974,754 Hydrous adhesive patch
Provided is a patch providing sufficiently high absorbability of dexmedetomidine and less skin irritation. Hydrous adhesive patch comprising dexmedetomidine or...
US-9,974,753 Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and...
The present invention relates to nanoparticles for encapsulating compounds, the preparation and uses thereof, said nanoparticles being based on a vegetable...
US-9,974,752 Methods and compositions particularly for treatment of attention deficit disorder
There is described, inter alia, a coated bead comprising: (a) a granule; (b) a first layer coated over the granule, the first layer comprising a first amount of...
US-9,974,751 Abuse resistant drug formulation
A pharmaceutical composition may include a granulate which may include at least one active pharmaceutical ingredient susceptible to abuse by an individual mixed...
US-9,974,750 Synthesis of ifflaionic acid nanoparticles
Synthesis of ifflaionic acid nanoparticles includes dissolving a powder of ifflaionic acid in an alcohol solution to form a first solution, adding the first...
US-9,974,749 Method of treating diabetic wounds using biosynthesized nanoparticles
The method of treating diabetic wounds using biosynthesized nanoparticles includes administering an effective amount of silver and gold nanoparticles to a...
US-9,974,748 Reduction of flake-like aggregation in nanoparticulate active agent compositions
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising...
US-9,974,747 Reduction of flake-like aggregation in nanoparticulate active agent compositions
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising...
US-9,974,746 Reduction of flake-like aggregation in nanoparticulate active agent compositions
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising...
US-9,974,745 Encochleation methods, cochleates and methods of use
Disclosed are novel methods for making cochleates and cochleate compositions that include introducing a cargo moiety to a liposome in the presence of a solvent....
US-9,974,744 Sustained release formulation of a non-steroidal anti-inflammatory drug
Disclosed are formulations comprising multivesicular liposomes and one or more non-steroidal anti-inflammatory drugs which minimize the side effects of...
US-9,974,743 Device and method for delivery of a medicament
The disclosure relates to an improved method of enhancing nicotine concentrations in a gaseous carrier. The methods are adaptable to the delivery of nicotine...
US-9,974,742 Emulsion formulations of an NK-1 receptor antagonist and uses thereof
Disclosed herein are novel pharmaceutical formulations of a neurokinin-1 (NK-1) receptor antagonist suitable for parenteral administration including intravenous...
US-9,974,740 Sensation masking composition
The present invention provides masking compositions that include a lower alkyl carboxylic acid, e.g. acetic acid. Also provided is a masking composition that...
US-9,974,739 Food and beverage compositions infused with lipophilic active agents and methods of use thereof
Aspects described herein relate to food and beverage compositions infused with lipophilic active agents and methods of use for the treatment of a variety of...
US-9,974,738 Disintegrating particle composition produced by two-stage wet granulation process, and intraorally...
A method is used in the production of a disintegrative particulate composition including three components consisting of a first disintegrator component having...
US-9,974,737 Adenovirus formulations
This disclosure provides pharmaceutical adenovirus formulations, in particular, liquid pharmaceutical formulations comprising adenoviruses.
US-9,974,736 Veterinary pharmaceutical compositions and method for the production thereof
The invention relates to an oily composition of a non-steroidal anti-inflammatory agent (NSAIA) for parenteral administration with at least one micronized...
US-9,974,735 Depilatory compositions
The present invention is directed to a depilatory composition which comprises a depilatory active and at least one material which alters the thermal properties...
US-9,974,734 Cosmetic composition for moisturizing keratinic tissue
The present invention is directed to a cosmetic composition comprising (a) an emulsifier selected from: (i) glyceryloleate citrate combined with a native oil as...
US-9,974,733 Tanning massage creme, extender, buffer and method of application
The present invention is a massage tanning creme formula to color skin of a person to appear tanned. The application of the formula, first including performing...
US-9,974,732 Cleansing composition
Cleansing composition comprising the following components (A), (B), and (C): (A) 0.02% by mass or larger and 10% by mass or smaller of a polymer comprising 85...
US-9,974,731 Method for producing functional lubricant and particulate material set used in the method
A method for producing a functional lubricant includes mixing particulate sodium polyacrylate alone with water, adding a particulate carbonate which is any one...
US-9,974,730 Oral care compositions and methods
Provided is an oral care composition comprising a phosphate/acrylate co-polymer, a tartar control agent, and an orally acceptable carrier and methods of using...
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