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Patent # Description
US-9,987,358 Nanostars and nanoconstructs for detection, imaging, and therapy
A polymer-free synthesis method is provided for preparation of monodisperse nanostars. The nanostars can be used for treating and imaging cells in in vivo or ex...
US-9,987,357 Methods and monitoring of treatment with a WNT pathway inhibitor
Methods for treating diseases such as cancer comprising administering a Wnt pathway inhibitor, either alone or in combination with other anti-cancer agents, and...
US-9,987,356 Anti-CD40 antibodies and methods of administering thereof
The present invention relates to antibodies specific for a particular epitope on CD40 and antibodies that bind CD40 and have particular functional...
US-9,987,355 Vaccine composition containing synthetic adjuvant
Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery...
US-9,987,354 Tolerogenic synthetic nanocarriers for antigen-specific deletion of T effector cells
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering immunosuppressants and MHC Class I-restricted and/or MHC Class...
US-9,987,353 Virus like vesicles (VLVS) based vaccines to prevent or treat chronic hepatitis B virus (HBV) infection
The present invention relates to the discovery of compositions and methods for therapeutic immunization for treatment of chronic hepatitis B. Methods of the...
US-9,987,352 Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection
Disclosed are immunotherapeutic compositions and methods for preventing and/or treating hepatitis delta virus (HDV) infection, including yeast-based HDV...
US-9,987,351 Lentiviral vectors for generating immune responses against human T Lymphotrophic Virus Type 1
The present invention relates to compositions, methods, and uses employing lentiviral vector particles for induction of an immune response by administration to...
US-9,987,350 Antigens and vaccines directed against human enteroviruses
The instant invention provides materials and methods for producing immunologically active antigens derived from members of the Picornaviridae virus family. The...
US-9,987,349 Use of a PCV2 immunogenic composition for lessening clinical symptoms in pigs
The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 2 (PCV2) antigen for treatment of several...
US-9,987,348 PCV2B divergent vaccine composition and methods of use
This invention provides a vaccine composition for protecting pigs against PCV2, including a highly virulent porcine circovirus type 2b (PCV2b) divergent strain,...
US-9,987,347 Vaccines against multiple subtypes of dengue virus
An aspect of the present invention is related to nucleic acid constructs capable of expressing a polypeptide, such as a consensus dengue prME that elicits an...
US-9,987,346 Methods and compositions for vaccinating a subject for a sexually transmitted pathogen
Purified Chlamydia major outer membrane protein (MOMP) has been observed to induce protection against genital and respiratory challenge in mice. MOMP contains...
US-9,987,345 OMV vaccines
The invention is in the field of outer membrane vesicles (OMV) and their uses. More particularly the present invention provides OMV obtained from a bacterium...
US-9,987,344 Pseudomonas antigens and antigen combinations
An effective Pseudomonas aeruginosa vaccine may require one or several antigenic components, and so various antigens of P. aeruginosa are identified for use in...
US-9,987,343 Haemophilus influenzae type IV pili
The invention described herein relates to a Haemophilus influenzae (H. influenzae) regulon encoding type IV pili. In particular, the invention relates to type...
US-9,987,342 Immunizing composition
The present invention is concerned with an antigenic composition comprising at least one antigen that comprises at least one antigenic epitope or antigenic...
US-9,987,341 PCSK9 vaccine
The present invention relates to the provision of novel immunogens comprising an antigenic PCSK9 peptide linked to an immunogenic carrier for the prevention,...
US-9,987,340 Compositions and methods of using chondroitinase ABCI mutants
The present disclosure relates to protein and nucleic acid mutants of chondroitinase ABCI. Such nucleic acid mutants encode for chondroitinase ABCI mutant...
US-9,987,339 Pharmaceutical composition with improved stability containing factor VII fusion protein
The present invention provides a pharmaceutical composition with improved stability, comprising a fusion protein comprising Factor VII (FVII) and transferrin,...
US-9,987,338 Mitrecin a polypeptide with antimicrobial activity
The present invention provides a Mitrecin A polypeptide useful in prevention and treatment of one or more bacteria. Also provided is a method to kill or prevent...
US-9,987,337 Compositions and methods comprising serratia peptidase for inhibition and treatment of biofilms related to...
Physiologically acceptable anti-biofilm compositions comprising Serratia peptidase and optionally one or more of bromelain, papain and a fibrinolytic enzyme....
US-9,987,336 Attenuating or treating sepsis or septic shock
Methods for attenuating or treating, or reducing the mortality of sepsis or septic shock using an ectonucleotidase such as CD39 or CD73 are provided.
US-9,987,335 Treatment of short bowel syndrome patients with colon-in-continuity
Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as...
US-9,987,334 Treatment of short bowel syndrome patients with colon-in-continuity
Intestinal absorption is enhanced in short bowel syndrome patients presenting with colon-in-continuity by treatment with a GLP-2 receptor agonist, such as...
US-9,987,333 Method for suppressing malignant tumor metastasis
A medicinal composition for suppressing or preventing the metastasis of a malignant tumor, the composition comprising, as an active ingredient, at least one...
US-9,987,332 Pharmaceutical composition for use in the treatment of a neurodegenerative disease
The present invention refers to a pharmaceutical composition for use in the treatment of a neurodegenerative disease.
US-9,987,331 Treating cardiovascular or renal diseases
This document provides methods and materials for treating cardiovascular and/or renal diseases. For example, AAV9 vectors designed to express natriuretic...
US-9,987,330 Methods of treating or preventing pruritis by blocking natriuretic polypeptide B
Disclosed is a method of treating, reducing, or preventing pruritis in a mammal, the method comprising administering at least one natriuretic polypeptide b...
US-9,987,329 Methods for treating peripheral nerve damage
VEGF-B, as well as a combination of VEGF-B and VEGF-A, mediates peripheral nerve repair. Methods to treat damage to the peripheral nervous system are described.
US-9,987,328 Factor XII inhibitors for the administration with medical procedures comprising contact with artificial surfaces
An inhibitor of FXII/FXIIa for the prevention of the formation and/or stabilization of thrombi during and/or after a medical procedure performed on a human or...
US-9,987,327 Methods for treating myocardial infarction comprising administering sonic hedgehog
The present invention relates to methods and pharmaceutical compositions for cardioprotection of subjects who experienced a myocardial infarction. In...
US-9,987,326 Klotho protein and related compounds for the treatment and diagnosis of cancer
Disclosed is the use of a klotho protein or related compounds for the diagnosis and treatment of cancer, alone or together with other active pharmaceutical...
US-9,987,325 Plant extract composition for reducing localized fat and promoting weight loss as well as application thereof
Provided is a composition and a pharmaceutical composition for reducing localized fat or promoting weight loss, wherein the composition comprises a plant...
US-9,987,324 Traditional chinese medicine composition and the use thereof
The present invention relates to the technical field of Chinese medicine, in particular to a traditional Chinese medicine composition and the use thereof. The...
US-9,987,323 Process to enhance the bioactivity of Ashwagandha extracts
The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and...
US-9,987,322 Treatment of pain in peripheral neuropathy using topical hamelia patens extract
Methods are provided for relieving pain associated with peripheral neuropathy, by topical application to human skin of a topical composition comprising Hamelia...
US-9,987,321 Use of flaxseed and flaxseed derivatives for treatment of neurological disorders and viral diseases
The invention provides compositions and methods for treating neurological disorders and viral infection using whole-grain flaxseed, flaxseed lignans such as...
US-9,987,320 Traditional chinese medicine composition, and preparation and application thereof
A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof,...
US-9,987,319 Essential element management
The invention extends the utility of apparatus used to extract medicinal cannabis compounds into an eluate by separating a portion of medicinal cannabis...
US-9,987,318 TNF-alpha inhibitor
An anti-inflammatory composition for inhibiting the secretion of cytokines, with the composition being based on a decoction of papaya leaves, a method of...
US-9,987,317 Cardio-protective agents from kiwifruits
The invention relates to cardio-protective agents. In particular, the present invention relates to cardio-protective extracts and fractions thereof prepared...
US-9,987,316 Probiotic controlling fungi and uses thereof
A method for controlling detrimental oral organisms in various individuals includes administering a priobiotic composition that includes one or more species or...
US-9,987,315 Use of a combination of Myxoma virus and rapamycin for therapeutic treatment
The present invention relates to therapeutic use of a combination of Myxoma virus, including in combination with rapamycin. Treatment with rapamycin enhances...
US-9,987,314 Oncolytic adenoviruses armed with heterologous genes
The present disclosure relates to a group B adenovirus comprising a sequence of formula (I): 5'ITR-B1-BAB2-BX-BB-BY-B3-3'ITR wherein: B1 is bond or comprises:...
US-9,987,313 Lactobacillus supplement for alleviating type 1 diabetes
Isolated Lactobacillus strains are useful in preventing or delaying the development of Type 1 Diabetes (T1D). A probiotic composition comprising the...
US-9,987,312 Mixture, dissolving solution and pharmaceutical agent each comprising thermophilic microorganism
To provide a mixture, a dissolving solution and a pharmaceutical agent, which contain a thermophilic microorganism to make it possible to regulate a mucous...
US-9,987,311 Compositions comprising bacterial strains
The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
US-9,987,310 Cardiac progenitor cells and methods of use therefor
Provided are pharmaceutical compositions that include a pharmaceutically acceptable carrier and isolated post-natal cardiac progenitor cells (CPCs) and/or...
US-9,987,309 Direct reprogramming of cells to cardiac myocyte fate
A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA...
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