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Patent # Description
US-9,993,519 Anticancer peptide for inhibiting proliferation of cancer stem cells and use thereof
The present invention relates to an anticancer composition comprising a peptide that inhibits the proliferation of cancer stem cells present in tumor tissue and...
US-9,993,518 Association of a tetrapeptide and a glyceryl ester for treating androgenic alopecia
An association comprising a peptide is described containing the sequence A-Lys-Gly-His-Lys-NH.sub.2 (SEQ ID NO: 1), wherein A is the radical corresponding to a...
US-9,993,517 Methods and compositions for preserving retinal ganglion cells
Provided are methods and compositions for maintaining the viability of retinal ganglion cells in a subject with an ocular disorder including, for example,...
US-9,993,516 Treatment of left ventricular non-compaction and dilated cardiomyopathy by inhibiting melanocortin receptor four
The present disclosure provides methods and compositions for treatment of left ventricular non-compaction and dilated cardiomyopathies.
US-9,993,515 Methods of treatment using water-soluble tryptophan-containing peptides obtained by the hydrolysis of hens eggs...
The present invention relates to a process to produce a composition comprising water-soluble peptides and having a Trp/LNAA ratio of more than 0.15, which...
US-9,993,514 Compounds
A compound of formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof, compositions, combinations and medicaments containing said compounds...
US-9,993,513 Preparation made from oatmeal and method for its use
A preparation is disclosed, made of, preferably colloidal, oat flour, along with the same for use in the treatment of diseases, further cosmetic methods,...
US-9,993,512 Use of escin
The present invention provides the use of escin for the manufacture of a pharmaceutical preparation for the treatment diseases mediated or caused by activated...
US-9,993,511 Pharmaceutical compositions for treating thermal injuries and wounds combined with bone injuries
The present invention relates to a pharmaceutical composition for treating thermal injuries and wounds combined with bone injuries. More specifically, the...
US-9,993,510 Acne-removing traditional chinese medicine composition and preparation method thereof
Disclosed are an acne-removing traditional Chinese medicine composition and a preparation method thereof, wherein the traditional Chinese medicine composition...
US-9,993,509 Method for regulating blood glucose level
A method for increasing the expression of SIRT1 mRNA and/or decreasing the expression of SOCS3 mRNA, and especially for regulating blood glucose levels in a...
US-9,993,508 Composition comprising banyan tree, lotus, and clover serum fractions (aging)
The present invention relates to compositions comprising banyan tree, lotus, and clover serum fractions. A method of improving the appearance of aging skin may...
US-9,993,507 Methods of improving milk production and compositional characteristics
The disclosure relates to isolated microorganisms--including novel strains of the microorganisms--microbial consortia, and compositions comprising the same....
US-9,993,506 Methods for the treatment of degenerative disc diseases by human birth tissue material composition
Methods for treating degenerative disc disease by administering a human birth tissue material composition are provided. The method includes the step of...
US-9,993,505 Innervation of engineered structures
Methods of generating an innervated muscle structures are disclosed as well as bioengineered structures for tissue repair or regeneration. The methods can...
US-9,993,504 Methods and compositions for generating chondrocyte lineage cells and/or cartilage like tissue
A method for generating chondrocytes and/or cartilage, optionally articular like non-hypertrophic chondrocyte cells and/or cartilage like tissue and/or...
US-9,993,503 Methods for production of platelets from pluripotent stem cells and compositions thereof
Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are...
US-9,993,502 Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene
Disclosed herein is a genetically-modified cell comprising in its genome a modified human T cell receptor alpha constant region gene, wherein the cell has...
US-9,993,500 Proton-binding polymers for oral administration
Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical...
US-9,993,499 Product for and method of protecting and increasing friction of animal paws
An adhesive and solid particulates adhered to the pads of an animal's paw, the adhesive being cured, thereby increasing the friction of the surface of the pads;...
US-9,993,498 Method for the prevention and treatment of gastrointestinal distress in horses and other species
Embodiments of a method and supplement for preventing and/or treating gastrointestinal distress, including ulcer conditions, in animals are disclosed. The...
US-9,993,497 Use of alginate compositions in preventing or reducing liver damage caused by a hepatotoxic agent
Disclosed herein are compositions, methods and uses utilizing alginate compositions, for treating, preventing and/or reducing liver damage induced by a...
US-9,993,496 Method of administering hyaluronan formulation for supporting joint health
Disclosed is a method for mitigating or ameliorating osteoarthritis in vertebrate subjects including administering to a subject a therapeutically effective...
US-9,993,495 Intrapulmonary administration of polynucleotide toll-like receptor 9 agonists for treating cancer of the lung
The present disclosure relates to methods for treating cancer by intrapulmonary administration of a polynucleotide Toll-like receptor 9 agonist. The methods of...
US-9,993,494 Compositions and methods for treating fibrotic disease
The present disclosure relates to compositions and methods for treating or preventing a fibrotic disorder or disease.
US-9,993,493 Composition for prevention, amelioration or treatment of metabolic syndrome
A composition comprising (a) and (b), and a food or drink or a medicine comprising the composition, wherein (a) is at least a kind of polyphenols selected from...
US-9,993,492 Lysophospholipids and lysophospholipid analogues against honeybee brood diseases
The present invention refers to a compound selected from the group consisting of a lysophospholipid and a lysophospholipid analog for use in the treatment or...
US-9,993,491 Guanine riboswitch binding compounds and their use as antibiotics
The present invention includes novel compounds and pharmaceutically acceptable formulations of said compounds which exhibit antibiotic activity against...
US-9,993,490 Phosphonic acid compounds and screening method
The present invention relates to pharmaceutical compositions comprising a phosphonic acid compound, such as a natural product. Such compounds can include, such...
US-9,993,489 Methods for treating solid tumor cancers using a histone deacetylase inhibitor and an I.kappa.B kinase inhibitor
Methods for the treatment of solid tumor cancers, specifically ovarian cancer and drug-resistant solid tumors, are disclosed. A method comprises administering a...
US-9,993,488 Dry powder formulations for inhalation
A respirable dry powder including acetylsalicylic acid in particles having a mass median aerodynamic diameter (MMAD) within a range of about 0.5 .mu.m to about...
US-9,993,487 Cyclodextrin and budesonide derivative compositions and methods
The present invention relates to novel and useful pharmaceutical compositions formulated with a cyclodextrin compound and a budesonide derivative for the...
US-9,993,486 Oral quetiapine suspension formulations with extended shelf life and enhanced bioavailability
A quetiapine fumarate composition for oral administration is provided comprising a pharmaceutically acceptable salt or solvate of quetiapine existing as a...
US-9,993,485 Highly concentrated stable meloxicam solutions for needleless injection
An aqueous cyclodextrin-free solution of meloxicam suitable is provided for administration by needleless injection, containing a pharmacologically acceptable...
US-9,993,484 2-(morpholin-4-yl)-1,7-naphthyridines
The present invention relates to substituted 2-(morpholin-4-yl)-1,7-naphthyridine compounds of general formula (I) or (1b), to methods of preparing said...
US-9,993,483 Compositions and methods for treating ophthalmic, octic, or nasal infections
The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a composition...
US-9,993,482 Pharmaceutical combination comprising a class III receptor tyrosine kinase inhibitor and the alkylating...
The present invention is directed to a combination comprising a class III receptor tyrosine kinase inhibitor and a compound of formula I or a pharmaceutically...
US-9,993,481 Methods and compositions for the treatment of metabolic disorders
The present invention is directed to a novel methods and compositions for the therapeutic intervention in hyperphenylalaninemia. More specifically, the...
US-9,993,480 mTOR/JAK inhibitor combination therapy
Provided herein is a combination therapy comprising an mTOR inhibitor and a JAK inhibitor. The combination therapy is useful for the treatment of a variety of...
US-9,993,479 Trk-inhibiting compound
The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related...
US-9,993,478 1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas as P38 MAP knase inhibitors
There are provided compounds of formula (I) which are inhibitors of the family of p38 mitogen-activated protein kinase enzymes, and to their use in therapy,...
US-9,993,477 Substituted imidazo[1,5-a]pyrazines as PDE9 inhibitors
This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically...
US-9,993,476 Substituted 5-flouro-1H-pyrazolopyridines and their use
The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations...
US-9,993,475 Method for treating a pulmonary hypertension condition
A method for treating a pulmonary hypertension condition such as pulmonary arterial hypertension (PAH) in a subject comprises administering to the subject a...
US-9,993,474 Bromocriptine formulations
The present application describes pharmaceutical formulations of bromocriptine mesylate and methods of manufacturing and using such formulations. The...
US-9,993,473 Crystalline forms of tyrosine kinase inhibitors and their salts
The invention relates to various polymorphic forms and amorphous form of sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol- ...
US-9,993,472 Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2
Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic...
US-9,993,471 Ophthalmic formulations of cetirizine and methods of use
The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in...
US-9,993,470 Combination therapy
Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound...
US-9,993,469 Combination therapy comprising oxazolidinone-quinolones for use in treating bacterial infections
The present invention provides a combination of at least one oxazolidinone-quinolone hybrid with at least one further antibacterial compound and the use thereof...
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