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Patent # Description
US-9,994,894 Method and components for detecting nucleic acid chains
The invention relates to a novel method for the enzymatic marking of nucleic acid chains (target sequences) by means of nucleotide conjugates. Said nucleotide...
US-9,994,893 Compositions and methods for functional quality control for human blood-based gene expression products
Methods for assessing the integrity of an RNA sample from a given tissue or blood type are disclosed.
US-9,994,892 Instantaneous detection of biomarks and uses thereof
The present invention relates to a novel method for detecting instantaneously a biomarker immobilized to a solid surface and related uses. The method comprises...
US-9,994,891 Sample processing method and sample processing cartridge
The present invention pertains inter alia to a method for analyzing a sample comprising biomolecules, which comprises the following steps: A a) lysing the...
US-9,994,890 Methods of natural product drug discovery
Disclosed are methods of identifying compounds that suppress the growth of target cells. In certain embodiments, the methods comprise providing a panel of...
US-9,994,889 Advanced microplate, microtiter, and microarray technologies with per-well fluidics, gas exchange, electronic...
Arrangements for per-well fluidics, gas exchange, and electronic sensors for microplate, microtiter, and microarray technologies are presented. In example...
US-9,994,888 Process for preparing genetically transformed yeasts capable of producing a molecule of interest at a high titre
The subject of the present invention is a process for preparing a genetically modified yeast by multicopy integration of at least four expression cassettes,...
US-9,994,887 Methods and compositions for improving efficiency of nucleic acids amplification reactions
The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid...
US-9,994,886 Modified Epstein-Barr virus DNA polymerase and methods for isothermal DNA amplification
Modified Epstein Barr Virus DNA polymerase for use in nucleic acid amplification, including isothermal nucleic acid amplification, in vitro are provided....
US-9,994,885 Nonribosomal peptide synthetases
The present disclosure is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention...
US-9,994,884 Processes and methods of manufacture of arecoline
Processes and methods of manufacturing an areca fruit product. One process may include the steps of providing a plurality of areca fruits, drying the plurality...
US-9,994,883 Triterpenoid sapogenin production in plant and microbial cultures
The disclosure relates to a method for enhancing the biosynthesis and/or secretion of sapogenins in the culture medium of plant and microbial cell cultures....
US-9,994,882 Microorganism for producing L-glutamine and method for producing L-glutamine using same
Provided are a Corynebacterium glutamicum mutant that is resistant to high concentrations of L-glutamine, and a method of producing L-glutamine by using the...
US-9,994,881 Functionalized carboxylic acids and alcohols by reverse fatty acid oxidation in engineered microbes
Bacteria that run the beta oxidation cycle in reverse anabolic direction are provided, along with many novel primers to start the reverse cycle, pathways to...
US-9,994,880 Synthesis of long-chain polyunsaturated fatty acids by recombinant cell
The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and...
US-9,994,879 Method of producing formic acid
The invention relates to a micro-organism comprising a hydrogenase enzyme system which is capable of converting carbon dioxide into formic acid and a second...
US-9,994,878 Recombinant microorganisms and uses therefor
Bacteria are genetically engineered to produce 3-hydroxypropionate (3-HP). The bacteria are carboxydotrophic acetogens. The bacteria produce acetyl-coA using...
US-9,994,877 Yeast cell having acid tolerance, method of preparing yeast cell and use thereof
Provided are a genetically engineered yeast cell having increased activity of SUL1, STR3, HXT7, ERR1, GRX8, MXR1, GRE1, MRK1, AAD10 or a combination thereof,...
US-9,994,876 Engineering microbes and metabolic pathways for the production of ethylene glycol
The invention relates to recombinant cells and their use in the production of ethylene glycol.
US-9,994,875 Recombinant strain for producing 2,3-butanediol, comprising (a) inactivated lactate dehydrogenase and (b)...
The present invention relates to a recombinant strain for producing 2,3-butanediol, comprising (a) an inactivated lactate dehydrogenase and (b) an inactivated...
US-9,994,874 Method for producing alcohols and/or solvents from a biomass, including recirculating an internal flow...
The invention relates to a process for the production of alcohols from biomass that comprises a stage in which at least one aqueous internal flow that comprises...
US-9,994,873 Process for the production of alcohols and/or solvents from lignocellulosic biomass with acid recycle of solid...
The present invention describes a process for the production of alcohols and/or solvents from a cellulosic or lignocellulosic substrate, comprising at least the...
US-9,994,872 Integration of first and second generation bioethanol processes
The present invention presents an alternative to the direct implementation of an industrial scale second generation bioethanol process with the integration of...
US-9,994,871 Method for producing myo-inositol and myo-inositol derivative
To impart significantly improved myo-inositol producing capability, suitable for use in recombinant DNA techniques and synthetic biology methods, to a host...
US-9,994,870 Method for generating methane from a carbonaceous feedstock
The present invention provides a method for generating methane from a carbonaceous feedstock with simultaneous in situ sequestration of carbon dioxide to afford...
US-9,994,869 Method for producing isoprene using recombinant halophilic methanotroph
The present invention relates to a recombinant methanotroph having an ability to produce isoprene and a method for producing isoprene using the same, and more...
US-9,994,868 Method and culture medium for preparing mammalian ovum or embryo in which zona pellucida has been thinned or...
Provided are a method for preparing a mammalian ovum or embryo in which zona pellucida has been thinned or eliminated, and a method for fertilization using the...
US-9,994,867 Method of targeting gene delivery using viral vectors
Methods and compositions are provided for delivering a polynucleotide encoding a gene of interest to a target cell using a virus. The virus envelope comprises a...
US-9,994,866 Expression vector system comprising two selection markers
The invention pertains to an expression vector or a combination of at least two expression vectors comprising at least (a) a polynucleotide encoding a product...
US-9,994,865 PEG-Prom mediated surface expression of avidin/streptavidin
The presently disclosed subject matter relates to compositions and methods directed to cancer theranostic nucleic acid constructs that permit simultaneous...
US-9,994,864 Rust resistance gene
The present invention relates to new transporter polypeptides, and genes encoding therefor, which can be used to confer upon a plant resistance to one or more...
US-9,994,863 Glyphosate tolerant corn event VCO-O1981-5 and kit and method for detecting the same
The present invention relates to the field of plant transformation with genes conferring tolerance to glyphosate. The invention particularly relates to a maize...
US-9,994,862 Rice resistant to HPPD and ACCase inhibiting herbicides
Rice is described that is tolerant/resistant to a plurality of herbicides, for example, ACCase and HPPD inhibitors. Use of the rice for weed control and methods...
US-9,994,861 Disease resistant grape plants
The present invention relates to a plant, which is resistant to a pathogen of viral, bacterial, fungal or oomycete origin, wherein the plant has a reduced...
US-9,994,860 Regulating alkaloids
MPO1 and MPO2 can be regulated for either decreasing or increasing alkaloid levels in plants, in particular in Nicotiana plants. In particular, suppressing or...
US-9,994,859 Plant produced human papillomavirus pseudovirion
The present invention relates to a method of producing HPV pseudovirions in plant cells, the plant produced pseudovirions per se, a neutralization assay using...
US-9,994,858 Constructs for gene expression analysis
The present invention relates generally to constructs and their use in gene expression or gene regulation assays. More particularly, the present invention...
US-9,994,857 PDGF and VEGF aptamers having improved stability and their use in treating PDGF and VEGF mediated diseases and...
Aptamers having improved stability against nucleases that bind PDGF and aptamers that bind VEGF are provided. In addition, aptamer constructs comprising a PDGF...
US-9,994,856 Method for increasing the activity of a cystic fibrosis transmembrane conductance regulator protein
The present invention relates to the field of gene therapy, more specifically to oligonucleotides for making a change in the sequence of a target RNA molecule...
US-9,994,855 Compositions and methods for modulating growth hormone receptor expression
The present embodiments provide methods, compounds, and compositions for treating, preventing, ameliorating a disease associated with excess growth hormone...
US-9,994,854 Cytotoxic T cell response modifiers
The present invention relates to a compound selectively binding to a sensory receptor or selectively altering the expression of a sensory receptor for use in a...
US-9,994,853 Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
The present invention relates to a multifunctional short interfering nucleic acid (siNA) having a structure of Formula MF-III: ##STR00001## wherein each X, X',...
US-9,994,852 Oligonucleotide compositions and uses thereof
The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof. The invention further provides methods for treating cancer such...
US-9,994,851 Antisense oligonucleotides for inducing exon skipping and methods of use thereof
An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 214.
US-9,994,850 Antisense design
A novel class of pharmaceuticals which comprises a Locked Nucleic Acid (LNA) which can be used in antisense therapy. These novel oligonucleotides have improved...
US-9,994,849 Method of separating senescent cells using overexpression of protocadherin
Provided is a method of separating senescent cells from a sample including the senescent cells, and a method of removing senescent cells from a sample or a...
US-9,994,848 Pharmaceutical composition for preventing and teating endocrine disrupting chemicals-induced diseases and...
A pharmaceutical composition for preventing and treating endocrine disrupting chemicals-induced diseases and a treating method using the same. Since the...
US-9,994,847 miR-29 mimics and uses thereof
The present invention relates to synthetic oligonucleotide mimetics of miRNAs. In particular, the present invention provides double-stranded, ...
US-9,994,846 MicroRNA compounds and methods for modulating miR-21 activity
Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modifications that yield potent...
US-9,994,845 Methods and compositions to inhibit metastasis and to treat fibrosis and to enhance wound healing
Methods and compositions are provided for inhibiting or treating metastasis based on discoveries regarding Kif19 and Cep192. Methods and compositions are...
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