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Patent # Description
US-1,000,4823 Method and system to detect that a device has been cleaned
A room monitoring system includes a plurality of in-room units. The in-room units collect information relating to a clean or dirty status of a plurality of...
US-1,000,4822 Mobile ultraviolet lamp apparatuses having a reflector system that redirects light to a high touch area of a room
Apparatuses having an ultraviolet light lamp are disclosed, where ultraviolet light is projected exterior to the apparatus and, in some embodiments, to a region...
US-1,000,4821 Ultraviolet treatment of light absorbing liquids
A system for providing ultraviolet treatment to light absorbing liquids, such as biological liquids in a medical instrument, is disclosed. The system can...
US-1,000,4820 Container for washing sterilization, transportation and sterile storage of articles
A container for washing, sterilization, transportation and sterile storage of articles for sterilization is provided. The container includes a sleeve and a...
US-1,000,4819 Tissue allograft sterilization method
The invention is a novel method of sterilizing bone and soft tissues intended for human transplantation. In one embodiment the process includes steps of...
US-1,000,4818 Ether and alkyl phospholipid compounds for treating cancer and imaging and detection of cancer
Methods and compositions utilizing ether and alkyl phospholipid ether analog compounds for treating cancer and imaging, monitoring, and detecting cancer stem...
US-1,000,4817 Diazacarbazole derivatives as tau-PET-ligands
The present invention relates to compounds that may be used for binding and imaging tau aggregates and related beta-sheet aggregates including, besides others,...
US-1,000,4816 X-ray imaging contrast media with low iodine concentration and X-ray imaging process
The present invention relates to X-ray examinations and to the improvement of patient safety during such. More specifically the invention relates to X-ray...
US-1,000,4815 Near-infrared quenching group
[Problem] To provide a novel near-infrared quencher. [Solution] A compound represented by general formula (I) or a salt thereof. ##STR00001##
US-1,000,4814 Systemic delivery of myostatin short interfering nucleic acids (siNA) conjugated to a lipophilic moiety
The present invention provides methods comprising the in vivo delivery of small nucleic acid molecules capable of mediating RNA interference and reducing the...
US-1,000,4813 Constructs containing multiple expression cassettes for cancer therapy
The present invention relates to the field of cancer treatment, particularly to a novel constructs useful for treating tumors expressing H19 and/or IGF-II. More...
US-1,000,4812 Antibody-drug conjugates and immunotoxins
The present invention relates to conjugates, in particular antibody-drug conjugates and immunotoxins, having the formula I: A-(L-D)p (I) or a pharmaceutically...
US-1,000,4811 Development of a highly efficient second generation nicotine-conjugate vaccine to treat nicotine addiction
The invention is directed to a conjugate which comprises an isolated adenovirus hexon protein coupled to nicotine or a nicotine analog, as well as a method of...
US-1,000,4810 Bio-orthogonal drug activation
The invention relates to a Prodrug activation method, for therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal...
US-1,000,4809 Precise delivery of therapeutic agents to cell mitochondria for anti-cancer therapy
Described is a targeted molecular scaffold for construction of a metabolic inhibitor loaded with cancer-cell specific activity and anti-tumor immunity....
US-1,000,4808 Methods of treating ulcerative colitis
Methods for inducing clinical remission of ulcerative colitis in a human patient are described comprising administration of an antibody that has binding...
US-1,000,4807 Pharmaceutical compositions comprising fatty acid esters
The present invention relates to an injectable, pharmaceutical composition comprising a C.sub.1-6 alkyl ester of a C.sub.10-20 fatty acid. In an embodiment, the...
US-1,000,4806 Periodontal regeneration composition and method of using same
A periodontal structure regeneration composition for treatment of periodontal disease is a mixture of particles of a bone growth material and free collagen. All...
US-1,000,4805 Proton induced boron capture therapy
The present disclosure recites a method of treating biological tissues. The method includes using a proton beam includes irradiating a proton beam to a...
US-1,000,4804 Cell lines that secrete anti-angiogenic antibody-scaffolds and soluble receptors and uses thereof
The invention provides nucleic acid and polypeptide sequences encoding antibody based scaffolds such as full antibodies, antibody Fab fragments, single chain...
US-1,000,4803 Low, immune enhancing, dose mtor inhibitors and uses thereof
The present invention relates, in part, to compositions and methods for enhancement of an immune response by partial mTOR inhibition, for example, with low,...
US-1,000,4802 Tolerogenic synthetic nanocarriers for generating CD8+ regulatory T cells
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes...
US-1,000,4801 HBV epitope reactive exogenous T cell receptor (TCR) and uses thereof
There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for...
US-1,000,4800 Antibody evolution immunogens
The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of...
US-1,000,4799 Composite antigenic sequences and vaccines
The invention relates to composite antigens comprising a peptide with contiguous amino acid sequence derived from a plurality of antigenic epitopes of one or...
US-1,000,4798 Compositions and methods of enhancing immune responses
Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response...
US-1,000,4797 Method of rapidly producing improved vaccines for animals
A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained...
US-1,000,4796 Adenoviral vector-based vaccine against enterovirus infection
The present invention relates to a recombinant adenoviral vector for generating immunity against enterovirus infection. In one embodiment, the recombinant...
US-1,000,4795 Process for preparing an attenuated tetravalent dengue vaccine
The present invention refers to a process for preparing an attenuated tetravalent dengue vaccine and its product. The present invention also refers to a process...
US-1,000,4794 Vectors for molecule delivery to CD11b expressing cells
The invention relates to a novel use of a Bordetella adenylcyclase toxin in the manufacturing of vectors for targeting in vivo a molecule of interest,...
US-1,000,4793 M.tuberculosis vaccines
The present invention is directed to a fusion protein, antigen cocktails and immunological compositions such as vaccines against infections caused by virulent...
US-1,000,4792 Peptides and combination of peptides for use in immunotherapy against various cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,000,4791 Peptide vaccines against PCSK9
The present invention relates to a vaccine capable to induce production of antibodies directed to PCSK9 in vivo.
US-1,000,4790 Nanospheres encapsulating bioactive material and method for formulation of nanospheres
A method of transdermal delivery of a vaccine, comprising preparing microparticles of encapsulated vaccine by spray drying a mixture of the vaccine and at least...
US-1,000,4789 Methods and apparatus for delivering a therapeutic agent to naspharyngeal mucosa targets
A system for delivering a therapeutic agent to a nasopharyngeal mucosa target comprises a foam generating mechanism, a gas, a therapeutic agent in liquid form...
US-1,000,4788 Treatment of ocular neovascularization using anti-VEGF proteins
The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by...
US-1,000,4787 Fibrinogen preparations enriched in fibrinogen with an extended alpha chain
The present invention relates to fibrinogen preparations enriched in .alpha.-extended fibrinogen. Compositions comprising such preparations show improved...
US-1,000,4786 Acylated glucagon analogues
The invention provides materials and methods for promoting weight loss or preventing weight gain, and in the treatment of diabetes and associated metabolic...
US-1,000,4785 LKKTET and/or LKKTNT peptide compositions which are lyophilized or in a form capable of being lyophilized
A composition including a peptide agent including amino acid sequence LKKTET [SEQ ID NO: 1] or LKKTNT [SEQ ID NO: 2], a conservative variant thereof, or a...
US-1,000,4784 Use of hepcidin as a regulator of iron homeostasis
The invention concerns the use of hepcidin for the diagnosis and therapy of disorders of iron homeostasis. Hepcidin can be used in the treatment of disorders...
US-1,000,4783 Method for delivering pramlintide into a lumen of the intestinal tract using a swallowable drug delivery device
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many...
US-1,000,4782 Glucokinase activator compositions for the treatment of diabetes
The present invention relates to pharmaceutical compositions comprising {2-[3-cyclohexyl-3-(trans-4-propoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfa- nyl}-acetic...
US-1,000,4781 Prescription of intravenous medication for blocking heroin or morphine intoxication path and using thereof
A prescription of intravenous medication and its treatment method block heroin or morphine intoxication. The prescription of intravenous infusion includes...
US-1,000,4780 Methods and pharmaceutical compositions for the treatment of age-related macular degeneration (AMD)
The present invention relates to methods and pharmaceutical compositions for the treatment of age-related macular degeneration (AMD). In particular the present...
US-1,000,4779 Elastin protective polyphenolics and methods of using the same
Dermal fibroblasts permanently loose their ability to synthesize elastin, the major component of elastic fibers, shortly after puberty. This progressive loss of...
US-1,000,4778 Method of making an Ajwa date-based treatment for snake envenomation
The method of making an Ajwa date-based treatment for snake envenomation is a method for preparing a composition for the treatment of local hemorrhage and edema...
US-1,000,4777 Bioactive compositions from Theacea plants and processes for their production and use
The present invention relates to isolated bioactive compositions containing bioactive fractions derived from Theacea plants. The present invention also relates...
US-1,000,4776 Pharmaceutical composition for preventing or treating skin cancer comprising Panax spp. plant extract and...
Provided are a pharmaceutical composition for preventing or treating skin cancer and a method of preventing or treating skin cancer in a subject by using the...
US-1,000,4775 Inhibition of hypoxia-inducible factor activity with carica papaya extracts
An extract of Carica papaya leaves obtained from a plant of age six months and younger from the date of germination of the seed is used as an inhibitor of HIF...
US-1,000,4774 Lozenge for treating sore throat, hoarseness and associated dry cough, and inflammatory diseases of the oral...
The present invention relates to a pharmaceutical formulation containing a combination of (a) at least one astringent active substance and (b) at least one...
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