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Patent # Description
US-1,000,4806 Periodontal regeneration composition and method of using same
A periodontal structure regeneration composition for treatment of periodontal disease is a mixture of particles of a bone growth material and free collagen. All...
US-1,000,4805 Proton induced boron capture therapy
The present disclosure recites a method of treating biological tissues. The method includes using a proton beam includes irradiating a proton beam to a...
US-1,000,4804 Cell lines that secrete anti-angiogenic antibody-scaffolds and soluble receptors and uses thereof
The invention provides nucleic acid and polypeptide sequences encoding antibody based scaffolds such as full antibodies, antibody Fab fragments, single chain...
US-1,000,4803 Low, immune enhancing, dose mtor inhibitors and uses thereof
The present invention relates, in part, to compositions and methods for enhancement of an immune response by partial mTOR inhibition, for example, with low,...
US-1,000,4802 Tolerogenic synthetic nanocarriers for generating CD8+ regulatory T cells
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes...
US-1,000,4801 HBV epitope reactive exogenous T cell receptor (TCR) and uses thereof
There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for...
US-1,000,4800 Antibody evolution immunogens
The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of...
US-1,000,4799 Composite antigenic sequences and vaccines
The invention relates to composite antigens comprising a peptide with contiguous amino acid sequence derived from a plurality of antigenic epitopes of one or...
US-1,000,4798 Compositions and methods of enhancing immune responses
Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response...
US-1,000,4797 Method of rapidly producing improved vaccines for animals
A method of quickly producing a vaccine for a biotype of pathogenic microorganism is described, where a nucleic acid molecule or fragment thereof is obtained...
US-1,000,4796 Adenoviral vector-based vaccine against enterovirus infection
The present invention relates to a recombinant adenoviral vector for generating immunity against enterovirus infection. In one embodiment, the recombinant...
US-1,000,4795 Process for preparing an attenuated tetravalent dengue vaccine
The present invention refers to a process for preparing an attenuated tetravalent dengue vaccine and its product. The present invention also refers to a process...
US-1,000,4794 Vectors for molecule delivery to CD11b expressing cells
The invention relates to a novel use of a Bordetella adenylcyclase toxin in the manufacturing of vectors for targeting in vivo a molecule of interest,...
US-1,000,4793 M.tuberculosis vaccines
The present invention is directed to a fusion protein, antigen cocktails and immunological compositions such as vaccines against infections caused by virulent...
US-1,000,4792 Peptides and combination of peptides for use in immunotherapy against various cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,000,4791 Peptide vaccines against PCSK9
The present invention relates to a vaccine capable to induce production of antibodies directed to PCSK9 in vivo.
US-1,000,4790 Nanospheres encapsulating bioactive material and method for formulation of nanospheres
A method of transdermal delivery of a vaccine, comprising preparing microparticles of encapsulated vaccine by spray drying a mixture of the vaccine and at least...
US-1,000,4789 Methods and apparatus for delivering a therapeutic agent to naspharyngeal mucosa targets
A system for delivering a therapeutic agent to a nasopharyngeal mucosa target comprises a foam generating mechanism, a gas, a therapeutic agent in liquid form...
US-1,000,4788 Treatment of ocular neovascularization using anti-VEGF proteins
The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by...
US-1,000,4787 Fibrinogen preparations enriched in fibrinogen with an extended alpha chain
The present invention relates to fibrinogen preparations enriched in .alpha.-extended fibrinogen. Compositions comprising such preparations show improved...
US-1,000,4786 Acylated glucagon analogues
The invention provides materials and methods for promoting weight loss or preventing weight gain, and in the treatment of diabetes and associated metabolic...
US-1,000,4785 LKKTET and/or LKKTNT peptide compositions which are lyophilized or in a form capable of being lyophilized
A composition including a peptide agent including amino acid sequence LKKTET [SEQ ID NO: 1] or LKKTNT [SEQ ID NO: 2], a conservative variant thereof, or a...
US-1,000,4784 Use of hepcidin as a regulator of iron homeostasis
The invention concerns the use of hepcidin for the diagnosis and therapy of disorders of iron homeostasis. Hepcidin can be used in the treatment of disorders...
US-1,000,4783 Method for delivering pramlintide into a lumen of the intestinal tract using a swallowable drug delivery device
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many...
US-1,000,4782 Glucokinase activator compositions for the treatment of diabetes
The present invention relates to pharmaceutical compositions comprising {2-[3-cyclohexyl-3-(trans-4-propoxy-cyclohexyl)-ureido]-thiazol-5-ylsulfa- nyl}-acetic...
US-1,000,4781 Prescription of intravenous medication for blocking heroin or morphine intoxication path and using thereof
A prescription of intravenous medication and its treatment method block heroin or morphine intoxication. The prescription of intravenous infusion includes...
US-1,000,4780 Methods and pharmaceutical compositions for the treatment of age-related macular degeneration (AMD)
The present invention relates to methods and pharmaceutical compositions for the treatment of age-related macular degeneration (AMD). In particular the present...
US-1,000,4779 Elastin protective polyphenolics and methods of using the same
Dermal fibroblasts permanently loose their ability to synthesize elastin, the major component of elastic fibers, shortly after puberty. This progressive loss of...
US-1,000,4778 Method of making an Ajwa date-based treatment for snake envenomation
The method of making an Ajwa date-based treatment for snake envenomation is a method for preparing a composition for the treatment of local hemorrhage and edema...
US-1,000,4777 Bioactive compositions from Theacea plants and processes for their production and use
The present invention relates to isolated bioactive compositions containing bioactive fractions derived from Theacea plants. The present invention also relates...
US-1,000,4776 Pharmaceutical composition for preventing or treating skin cancer comprising Panax spp. plant extract and...
Provided are a pharmaceutical composition for preventing or treating skin cancer and a method of preventing or treating skin cancer in a subject by using the...
US-1,000,4775 Inhibition of hypoxia-inducible factor activity with carica papaya extracts
An extract of Carica papaya leaves obtained from a plant of age six months and younger from the date of germination of the seed is used as an inhibitor of HIF...
US-1,000,4774 Lozenge for treating sore throat, hoarseness and associated dry cough, and inflammatory diseases of the oral...
The present invention relates to a pharmaceutical formulation containing a combination of (a) at least one astringent active substance and (b) at least one...
US-1,000,4773 Plant compositions and methods and uses thereof for treating elevated glucocorticoid related disorders, and anxiety
The disclosure provides compositions containing preparations from plants of the family Marcgraviaceae and from plants of the family Platanaceae. The disclosure...
US-1,000,4772 Materials and methods for improving immune responses and skin and/or mucosal barrier functions
The subject invention provides compositions and methods for treating human dermatological conditions by employing a microbiome-centered treatment approach....
US-1,000,4771 Method of identifying a biologically-active composition from a biofilm
The subject invention provides materials and methods that effectively support innate immunity and/or disperse pathogenic biofilms using readily available,...
US-1,000,4770 Production and use of bacterial histamine
A method is provided of selecting specific probiotic lactic acid bacteria producing histamine and the use of such strains for beneficial effects for mammals....
US-1,000,4769 Lactobacillus brevis G-101 strain and use thereof
The present invention relates to a novel Lactobacillus brevis G-101 strain capable of decomposing monosodium L-glutamate (MSG), and a functional health food, a...
US-1,000,4768 Treatment of atopic dermatitis and infectious dermatitis with biological spa therapy
Provided is a method for treatment of atopic dermatitis and infectious dermatitis with biological spa therapy. The method seeks to cure or alleviate symptoms of...
US-1,000,4767 Methods and compositions for producing hepatocyte-like cells
Methods are provided for producing a population of hepatocyte-like cells (iHeps) from a population of adipocyte-derived stem cells (ASCs). Aspects of the...
US-1,000,4766 Trabecular meshwork stem cells
Provided herein are isolated populations of multipotent stem cells capable of differentiating into trabecular meshwork (TM) cells, methods of obtaining an...
US-1,000,4765 Dosage compensating transgenes and cells
Methods and compositions for reducing expression of genes on Chromosome 21 ("Chr 21") by targeting an XIST transgene to the Dual specificity ...
US-1,000,4764 Red blood cell membrane-derived microparticles and their use for the treatment of lung disease
Cell-based therapies show considerable potential as an immunomodulatory strategy for a variety of lung diseases, including chronic obstructive pulmonary disease...
US-1,000,4763 Magnesium oxide granules for pharmaceutical applications or for use as food additives
An object of the present invention is to provide magnesium oxide that can be preferably used for pharmaceutical applications or as a food additive. In...
US-1,000,4762 Dialysis formulation
The invention relates to a dialysis formulation, optionally a citrate containing dialysis formulation, comprising selenium (Se), optionally in combination with...
US-1,000,4761 Malodor neutralizing composition
A composition suitable for treating a variety of medical, aesthetic and cosmetic conditions in mucous membranes and occluded skin areas, comprising hyaluronic...
US-1,000,4760 Microbubble complexes and methods of use
The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin...
US-1,000,4759 Remote loading of sparingly water-soluble drugs into lipid vesicles
The present invention provides liposome compositions containing sparingly soluble drugs that are used to treat life-threatening diseases. A preferred method of...
US-1,000,4758 Cyclic boronic acid ester derivatives and methods of making the same
Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic...
US-1,000,4757 Oral supplement
An oral, nonprescription supplement is described which may contain coenzyme Q10, niacin, and lecithin. The supplement may be sold over-the-counter and is...
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