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Patent # Description
US-1,001,0596 Bacterial live vector vaccines expressing chromosomally-integrated foreign antigens
Bacterial live vector vaccines represent a vaccine development strategy that offers exceptional flexibility. In the present invention, genes encoding protective...
US-1,001,0595 Live recombinant booster vaccine against tuberculosis
Embodiments of the invention comprise an improved vaccine for generating an immune response and preventing or treating mycobacterial diseases such as...
US-1,001,0594 Methods and compositions for transgene expression in a herpesvirus vector system
Compositions are provided comprising a replication-competent herpesvirus vector system and/or a herpesvirus vector particle comprising a heterologous...
US-1,001,0593 Recombinant Listeria vaccine strains and methods of using the same in cancer immunotherapy
The present invention provides methods of treating, protecting against, and inducing an immune response against a human papillomavirus-associated oropharyngeal...
US-1,001,0592 Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal...
The present invention relates to a nucleic acid sequence, comprising or coding for a coding region, encoding at least one peptide or protein comprising a tumor...
US-1,001,0591 Method of treating fibrosarcoma using a nucleic acid sequence encoding APOBEC3A
The present invention relates to the use of a nucleic acid that comprises a sequence encoding an APOBEC3A protein, in preventing or treating a tumor in a patient.
US-1,001,0590 Pharmaceutical compositions and methods
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter; and...
US-1,001,0589 Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof
Methods and compositions are provided for extending the half-life of a therapeutic agent. A modified therapeutic agent (mTA) comprises a therapeutic agent, a...
US-1,001,0588 Methods of using pegylated interleukin-10 for treating hyperlipidemia
Methods of treating subjects having diseases, disorders, or conditions, including disorders associated with cholesterol homeostasis, responsive to IL-10,...
US-1,001,0587 IL-2R.beta.-selective agonists in combination with an anti-CTLA-4 antibody or an anti-PD-1 antibody
The invention relates to (among other things) method of administering to a patient suffering from a cancer, the method comprising the steps of: (a) an...
US-1,001,0586 Method of treating intraocular tissue pathologies with nerve growth factor
Nerve Growth Factor (NGF), in the form of a preparation to be administered over ocular surface, is suggested as being suitable for therapy and/or prophylaxis of...
US-1,001,0585 Methods of treating vestibular schwannoma and reducing hearing or neurite loss caused by vestibular schwannoma
Methods to reduce the proliferation of vestibular schwannoma (VS) cells and/or provide neuroprotection to reduce the risk of sensorineural hearing loss (SNHL),...
US-1,001,0584 Treatment of depressive disorders
The invention provides for the use of carbonic anhydrase activators; protein kinase C activators and FGF-18 to treat depressive disorders. The invention also...
US-1,001,0583 Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO...
The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an...
US-1,001,0582 Soluble mediator
The present disclosure relates to a soluble CD52 glycoprotein and its use in treating diseases regulated by effector T-cells, for example autoimmune diseases...
US-1,001,0581 Syndecan peptides and polypeptides and uses thereof
The invention provides for peptides from syndecan 1 and methods of use therefor. These peptides can inhibit .alpha.4.beta.6 interaction with HER2, thereby...
US-1,001,0580 Insulin independence among patients with diabetes utilizing an optimized hamster Reg3 gamma peptide
Embodiments of the present invention provide for novel therapies, pharmaceutical compositions and methods for insulin independence utilizing a new optimized...
US-1,001,0579 Insulin independence among patients with diabetes utilizing an optimized hamster Reg3 gamma peptide
Embodiments of the present invention provide for novel therapies, pharmaceutical compositions and methods for insulin independence utilizing a new optimized...
US-1,001,0578 Insulin independence among patients with diabetes utilizing an optimized hamster Reg3 gamma peptide
Embodiments of the present invention provide for novel therapies, pharmaceutical compositions and methods for insulin independence utilizing a new optimized...
US-1,001,0577 Insulin independence among patients with diabetes utilizing an optimized hamster REG3 gamma peptide
Embodiments of the present invention provide for novel therapies, pharmaceutical compositions and methods for insulin independence utilizing a new optimized...
US-1,001,0576 Method of treatment
The present disclosure relates to the control of fungal infection of horn-like envelopes covering dorsal and terminal phalanges in humans and animals and...
US-1,001,0575 Vasopressin formulations for use in treatment of hypotension
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time at...
US-1,001,0574 Silk peptide for improving neuroprotective and neurofunctional effects and a method of its preparation
A silk peptide having neuroprotective and neurofunctional activities and its preparation method are discussed. One method relates to preparing silk protein...
US-1,001,0573 Engineered rice having alcoholism relief and liver protection function, and preparation method thereof
The present invention relates to a functional engineered rice having alcoholism relief and liver protection functions for those drinking alcohol over an...
US-1,001,0572 Composition for musculoskeletal pain
Described herein are compositions and methods of treatment for musculoskeletal pain.
US-1,001,0571 Nutritional supplement for the enhancement of muscle irisin and enhancement of brown fat, metabolic rate, and...
The present invention includes a method of activating irisin by administering to an individual in need of such treatment a composition comprising...
US-1,001,0570 Galenical solid
Preparation process for dietary supplements, comprising at least two steps, the first step of which is to obtain a basic composition comprising liquid vegetable...
US-1,001,0569 Seaweed extracts, unsaturated fatty acids, and methods of treatment
The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and...
US-1,001,0568 Method and system for reducing the likelihood of a spirochetes infection in a human being
A method and system of reducing the likelihood of an inflammatory disease developing by providing a mucosal adhesive strip to a subject, with the strip provided...
US-1,001,0567 Bioeffective krill oil compositions
This disclosure discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The...
US-1,001,0566 Compositions and methods useful for ameliorating age related maladies
The invention provides methods and compositions useful for ameliorating age related maladies, enhancing and maintaining immune function, enhancing and...
US-1,001,0565 Stimulation of ovarian follicle development and oocyte maturation
Methods are provided for stimulating ovarian preantral and antral follicles in a mammal.
US-1,001,0564 Camel milk-based topical pharmaceutical composition
The present invention relates to a novel pharmaceutical composition with milk of immunized camelid, particularly Camelus dromedarius as the main component (i.e....
US-1,001,0563 Peritoneal dialysis fluid
The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/L of icodextrin and 0 to 2.34 g/L of...
US-1,001,0562 Dual molecular delivery of oligonucleotides and peptide containing conjugates
Disclosed herein is a method for inhibiting expression of a gene of a subject comprising administering (1) a composition comprising R-(L).sub.a-(G).sub.b;...
US-1,001,0561 Method of treating cancer using high efficiency self-illuminative nanocomplexes and method of manufacturing the...
The present disclosure relates to a method of treating cancer using a composition including a target-specific self-illuminative nanocomplex which includes a...
US-1,001,0560 Small molecule HSP70 inhibitors
In an effort to discover therapies for treating HSP70 related diseases, a previously unidentified hydrophobic pocket was found in the C-terminal domain of DnaK...
US-1,001,0559 Use of derivatives containing C-O-P bonds in patients with kidney failure
Use of a derivative containing C--O--P bonds in a controlled release form to treat patients with kidney failure. Moreover, it comprises the use of said...
US-1,001,0558 Frankiamicin A compositions and methods
In one aspect, this disclosure describes a pharmaceutical composition that generally includes frankiamicin A and a pharmaceutically acceptable carrier. In...
US-1,001,0557 Cobalt porphyrins for the treatment of blood-related disorders
The use of cobalt porphyrins for the manufacture of an agent for mobilizing bone marrow cells to peripheral blood, preferably used to treat congenital...
US-1,001,0556 Bicyclic bromodomain inhibitors
The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical...
US-1,001,0555 Animal and human anti-trypanosomonal and anti-leishmania agents
Provided herein are Aminopurine compounds of Formula I: ##STR00001## or pharmaceutically acceptable salts, tautomers, isotopologues, or stereoisomers thereof,...
US-1,001,0554 Fused pyrimidines as inhibitors of P97 complex
Fused pyrimidine compounds having a saturated, unsaturated or aromatic A ring fused to a pyrimidine ring and having a complex substituents at the 2 position and...
US-1,001,0553 Organic compounds
The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of psychosis, schizophrenia, schizoaffective disorder,...
US-1,001,0552 Combination therapy comprising a CDK4/6 inhibitor and a PI3K inhibitor for use in the treatment of cancer
A combination of a CDK4/6 inhibitor and a P3Kinase inhibitor for the treatment of cancer.
US-1,001,0551 Pyrimidinyl-diazospiro compounds
The invention relates to spiro deriviatives, to the use of said derivatives in treating diseases and conditions mediated by modulation of voltage-gated sodium...
US-1,001,0550 Inhibitors of human phosphatidylinositol 3-kinase delta
Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3K.delta.) activity, and methods of treating diseases, such as disorders of immunity and...
US-1,001,0549 Biheteroaryl compounds and uses thereof
The present invention provides for compounds of Formula I-I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases)....
US-1,001,0548 2,4-disubstituted pyrimidines useful as kinase inhibitors
The present invention provides 2,4-disubstituted pyrimidine compounds useful as kinase inhibitors, pharmaceutically acceptable compositions thereof, and methods...
US-1,001,0547 Pharmaceutical compounds
This invention relates to compounds that inhibit or modulate the activity of Chk-1 kinase. Also provided are pharmaceutical compositions containing the...
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