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Patent # Description
US-1,001,1886 Grain-oriented electrical steel sheet and manufacturing method thereof
A grain-oriented electrical steel sheet to which electron beam irradiation is applied, has a film and a thickness of t (mm), wherein no rust is produced on a...
US-1,001,1885 Methods for producing titanium and titanium alloy articles
A method of producing an article selected from a titanium article and a titanium alloy article comprises melting feed materials with a source of hydrogen to...
US-1,001,1884 Methods and systems for predicting whether a subject has a cervical intraepithelial neoplasia (CIN) lesion from...
Methods of predicting whether a subject has a cervical intraepithelial neoplasia (CIN) lesion are provided. Aspects of the methods include obtaining both...
US-1,001,1883 Causative agents and diagnostic methods relating to rheumatoid arthritis
Methods, reagents and compositions thereof for predicting RA onset in susceptible individuals, diagnosing RA onset, and/or evaluating efficacy of a therapeutic...
US-1,001,1882 Photo-responsive composite actuator
A photo-responsive composite actuator according to the present invention includes a polymeric scaffold film; an azobenzene liquid crystal polymer applied on a...
US-1,001,1881 Alternative splicing variant of OATP1B3 mRNA
[PROBLEM TO BE SOLVED] An object of the present invention is to provide a novel tumor marker and use thereof. In more detail, the present invention provides a...
US-1,001,1880 Serum/plasma MicroRNAs and uses thereof
MicroRNAs are provided for evaluating the physiological and/or pathological condition of a subject; and a kit thereof is provided for evaluating the...
US-1,001,1879 Method to predict or diagnose a gastointestinal disorder or disease
The disclosure provides methods and compositions useful for identifying a subject's predisposition to a gastrointestinal disease or disorder.
US-1,001,1878 Compositions and methods for performing methylation detection assays
Provided herein is technology relating to performing methylation assays. In particular, the technology relates to internal controls for methylation assays.
US-1,001,1877 Treatment of bladder cancer to overcome chemoresistance
The disclosure demonstrates the correlation of the methylation status of the miR-193a gene and the expression level of the miR-193a-3p transcript with the...
US-1,001,1876 Method and system for prognosis and treatment of diseases using portfolio of genes
This disclosure generally relates to a method, a system and a kit for diagnosing and treating various disease conditions using the gene expression value in a...
US-1,001,1875 Methods and assays relating to Huntingtons disease and Parkinson's disease
Described herein are methods for the diagnosis, prognosis, and treatment of neurological conditions, e.g. Huntington's Disease, relating to the misregulation of...
US-1,001,1874 Androgen receptor mutation
Compositions and methods are provided for diagnosis, prognosis and treatment of AR-related diseases, such as prostate diseases, such as prostate cancer, breast...
US-1,001,1873 Diagnostic miRNA markers for Parkinson disease
The invention relates to methods for diagnosing Parkinson's Disease PAD) with miRNA markers. Towards the identification of biomarkers for diagnosis of PD, a...
US-1,001,1872 Methods and systems for processing polynucleotides
The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a...
US-1,001,1871 Compositions and methods for accurately identifying mutations
The present disclosure provides compositions and methods for accurately detecting mutations by uniquely tagging double stranded nucleic acid molecules with dual...
US-1,001,1870 Compositions and methods for identifying nucleic acid molecules
The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using...
US-1,001,1869 Selective amplification of overlapping amplicons
The present invention relates to a scalable multiplex PCR method that can simultaneously amplify overlapping amplicons without the drawbacks of conventional...
US-1,001,1868 Reactivity-dependent and interaction-dependent PCR
Methods, reagents, compositions, and kits for reactivity-dependent polymerase chain reaction (RD-PCR) and interaction-dependent polymerase chain reaction...
US-1,001,1867 Targeted sequencing technique for whole genome DNA methylation
This invention is directed to a guide positioning sequencing technology of whole-genome DNA methylation. The invention provides a new detection method of...
US-1,001,1866 Nucleic acid ligation systems and methods
The present disclosure relates to systems and methods for nucleic acid ligation. In particular, the present disclosure provides oligonucleotide adaptors for use...
US-1,001,1865 Systems for handling microfluidic droplets
The invention generally relates to assemblies for displacing droplets from a vessel that facilitate the collection and transfer of the droplets while minimizing...
US-1,001,1864 Multidimensional microdissection and morphological reconstruction of genomic or proteomic expression activity
A method of morphological reconstruction of biological activity in a tissue sample maps biological data resulting from analysis of tissue samples onto a 3-D...
US-1,001,1863 Methods for detecting enhanced NMDA receptor function and uses thereof
A method of determining the risk of cognitive decline in an aging subject is provided. The method includes analyzing an MRNA transcript including a GRIN2B...
US-1,001,1862 Method for relative quantification of changes in DNA methylation, using combined nuclease, ligation, and...
The present invention is directed to methods for identifying the presence of one or more methylated or unmethylated target nucleotide sequences in a sample that...
US-1,001,1861 Cleavable hairpin primers
Nucleic acid constructs and methods that provide superior prevention of primer-dimers and other artifacts of false priming events are disclosed. In particular,...
US-1,001,1860 Mass-spectrometric resistance determination by growth measurement
The invention relates to a mass-spectrometric method to determine microbial resistances to antibiotics, in which the microbes are cultured in a medium...
US-1,001,1859 Methods and materials for biosynthesis of mogroside compounds
The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for...
US-1,001,1858 Methods for producing polypeptides by regulating polypeptide association
In the course of the present invention, it was discovered that one could regulate association between polypeptides by modifying amino acid residues that form...
US-1,001,1857 Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated...
The invention provides mannosidases capable of uncapping mannose-1-phospho-6-mannose moieties and demannosylating phosphorylated N-glycans, methods of using...
US-1,001,1856 Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate...
The present invention provides methods and compositions for reducing lactate production and increasing polypeptide production in cultured cells. In one aspect,...
US-1,001,1855 Fractionated coupled apparatus for saccharifying biomass and method for saccharifying biomass using the same
The present invention relates to a fractionated coupled apparatus for saccharifying biomass and a method for saccharifying biomass using the apparatus, and more...
US-1,001,1854 Fatty acid productivity
The present disclosure relates to an engineered microbe capable of improved productivity of fatty acid or fatty acid derivative. An NAD.sup.+-dependent...
US-1,001,1853 Yeast having xylose assimilation ability and ethanol production ability
An object is to provide a thermotolerant yeast capable of assimilating xylose to produce ethanol or a mutant strain thereof and a method for producing ethanol...
US-1,001,1852 Method for producing methane by means of aerobic co-culture of anaerobic micro-organisms
The present invention relates to the biological production of methane (Biogas) by co-culture in an aerobic atmosphere of a methanogenic bacterium and of an...
US-1,001,1851 Method for digesting a biomass comprising lignin together with cellulose and/or hemicellulose
The invention relates to a method for digesting a biomass comprising, lignin, cellulose, and hemicellulose, comprising the steps of: (a) contacting the biomass...
US-1,001,1850 Using RNA-guided FokI Nucleases (RFNs) to increase specificity for RNA-Guided Genome Editing
Many studies have shown that CRISPR-Cas nucleases can tolerate up to five mismatches and still cleave; it is hard to predict the effects of any given single or...
US-1,001,1849 Nucleic acid-guided nucleases
Disclosed herein are nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Disclosed herein are engineered...
US-1,001,1848 System and method for delivery of substance into mammalian cells
The present invention is concerned with a system of delivering particles of nano-scale into mammalian cells with a diameter of 50 .mu.m or less. The system has...
US-1,001,1847 Alphaviral vectors and cell lines for producing recombinant proteins
The present invention relates to polynucleotides and alphaviral vectors for the expression of genes of interest in mammalian cells. Additionally, the invention...
US-1,001,1846 Transgenic plants containing soluble cell wall polysaccharides
The present invention provides a bio-fuel, wood or other product, such as a paper, textile or yarn product. The product can contain material from a transgenic...
US-1,001,1845 Soybean variety 01068893
The invention relates to the soybean variety designated 01068893. Provided by the invention are the seeds, plants and derivatives of the soybean variety...
US-1,001,1844 Biological indicator
This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for...
US-1,001,1843 Biological indicator
This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for...
US-1,001,1842 Escherichia coli cell line with thyA knockout, folA knockout, and one or both of folP knockout, and folK knockout
In this invention, cell lines are created for enzyme inhibitory testing of inhibitors against Plasmodium falciparum DHFR-TS and HPPK-DHPS. Provided the...
US-1,001,1841 Methods and devices for electromagnetic ligation of nucleic acids and electromagnetic transformation of cells
Described herein are methods and devices for ligating nucleic acids or nucleic acid fragments as well as methods for transforming or transfecting cells with...
US-1,001,1840 Engineering of multi-carbon substrate utilization pathways in methanotrophic bacteria
The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glycerol) as...
US-1,001,1839 Metabolic transistor in bacteria
The disclosure relates to a metabolic transistor in microbes such as bacteria and yeast where a competitive pathway is introduced to compete with a product...
US-1,001,1838 Yeast strain and microbial method for production of pentacyclic triterpenes and/or triterpenoids
The invention relates to a yeast strain and to a method for microbial production of pentacyclic triterpenes and/or triterpenoids in yeast. More particularly,...
US-1,001,1837 SiRNAs and their use in methods and compositions for the treatment and/or prevention of eye conditions
The present invention relates to methods, compositions and dosages that decrease IOP of the eye, comprising a 19 nucleotide double-stranded RNA molecule.
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