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Patent # Description
US-1,001,1859 Methods and materials for biosynthesis of mogroside compounds
The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for...
US-1,001,1858 Methods for producing polypeptides by regulating polypeptide association
In the course of the present invention, it was discovered that one could regulate association between polypeptides by modifying amino acid residues that form...
US-1,001,1857 Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated...
The invention provides mannosidases capable of uncapping mannose-1-phospho-6-mannose moieties and demannosylating phosphorylated N-glycans, methods of using...
US-1,001,1856 Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate...
The present invention provides methods and compositions for reducing lactate production and increasing polypeptide production in cultured cells. In one aspect,...
US-1,001,1855 Fractionated coupled apparatus for saccharifying biomass and method for saccharifying biomass using the same
The present invention relates to a fractionated coupled apparatus for saccharifying biomass and a method for saccharifying biomass using the apparatus, and more...
US-1,001,1854 Fatty acid productivity
The present disclosure relates to an engineered microbe capable of improved productivity of fatty acid or fatty acid derivative. An NAD.sup.+-dependent...
US-1,001,1853 Yeast having xylose assimilation ability and ethanol production ability
An object is to provide a thermotolerant yeast capable of assimilating xylose to produce ethanol or a mutant strain thereof and a method for producing ethanol...
US-1,001,1852 Method for producing methane by means of aerobic co-culture of anaerobic micro-organisms
The present invention relates to the biological production of methane (Biogas) by co-culture in an aerobic atmosphere of a methanogenic bacterium and of an...
US-1,001,1851 Method for digesting a biomass comprising lignin together with cellulose and/or hemicellulose
The invention relates to a method for digesting a biomass comprising, lignin, cellulose, and hemicellulose, comprising the steps of: (a) contacting the biomass...
US-1,001,1850 Using RNA-guided FokI Nucleases (RFNs) to increase specificity for RNA-Guided Genome Editing
Many studies have shown that CRISPR-Cas nucleases can tolerate up to five mismatches and still cleave; it is hard to predict the effects of any given single or...
US-1,001,1849 Nucleic acid-guided nucleases
Disclosed herein are nucleic acid-guided nucleases, guide nucleic acids, and targetable nuclease systems, and methods of use. Disclosed herein are engineered...
US-1,001,1848 System and method for delivery of substance into mammalian cells
The present invention is concerned with a system of delivering particles of nano-scale into mammalian cells with a diameter of 50 .mu.m or less. The system has...
US-1,001,1847 Alphaviral vectors and cell lines for producing recombinant proteins
The present invention relates to polynucleotides and alphaviral vectors for the expression of genes of interest in mammalian cells. Additionally, the invention...
US-1,001,1846 Transgenic plants containing soluble cell wall polysaccharides
The present invention provides a bio-fuel, wood or other product, such as a paper, textile or yarn product. The product can contain material from a transgenic...
US-1,001,1845 Soybean variety 01068893
The invention relates to the soybean variety designated 01068893. Provided by the invention are the seeds, plants and derivatives of the soybean variety...
US-1,001,1844 Biological indicator
This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for...
US-1,001,1843 Biological indicator
This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for...
US-1,001,1842 Escherichia coli cell line with thyA knockout, folA knockout, and one or both of folP knockout, and folK knockout
In this invention, cell lines are created for enzyme inhibitory testing of inhibitors against Plasmodium falciparum DHFR-TS and HPPK-DHPS. Provided the...
US-1,001,1841 Methods and devices for electromagnetic ligation of nucleic acids and electromagnetic transformation of cells
Described herein are methods and devices for ligating nucleic acids or nucleic acid fragments as well as methods for transforming or transfecting cells with...
US-1,001,1840 Engineering of multi-carbon substrate utilization pathways in methanotrophic bacteria
The present disclosure relates to genetically engineered methanotrophic bacteria with the capability of growing on a multi-carbon substrate (e.g., glycerol) as...
US-1,001,1839 Metabolic transistor in bacteria
The disclosure relates to a metabolic transistor in microbes such as bacteria and yeast where a competitive pathway is introduced to compete with a product...
US-1,001,1838 Yeast strain and microbial method for production of pentacyclic triterpenes and/or triterpenoids
The invention relates to a yeast strain and to a method for microbial production of pentacyclic triterpenes and/or triterpenoids in yeast. More particularly,...
US-1,001,1837 SiRNAs and their use in methods and compositions for the treatment and/or prevention of eye conditions
The present invention relates to methods, compositions and dosages that decrease IOP of the eye, comprising a 19 nucleotide double-stranded RNA molecule.
US-1,001,1836 Methods and compositions for selecting siRNA of improved functionality
Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize...
US-1,001,1835 miRNAs as novel therapeutic targets and diagnostic biomarkers for parkinson's disease
The disclosure provides pharmaceutical compositions including an oligonucleotide that down-regulates the over-expression of at least one miRNA of SEQ ID NOs:...
US-1,001,1834 Methods and compositions for the specific inhibition of HIF-1.alpha. by double-stranded RNA
This invention relates to compounds, compositions, and methods useful for reducing HIF-1.alpha. target RNA and protein levels via use of dsRNAs, e.g., Dicer...
US-1,001,1833 Bridged bicyclic nucleosides
The present invention relates to 2'-C-Bridged Bicyclic Nucleosides and Nucleotides, and oligonucleotides comprising at least one 2'-C-Bridged Bicyclic...
US-1,001,1832 SiRNA and their use in methods and compositions for the treatment and/or prevention of eye conditions
The present invention relates to methods, compositions and dosages that decrease IOP of the eye, comprising a 19 nucleotide double-stranded RNA molecule.
US-1,001,1831 Crude biological derivatives competent for nucleic acid detection
The invention relates to methods for the detection of a specific sequence of RNA in a cell or tissue sample. The invention also relates to methods to...
US-1,001,1830 Devices and methods for display of encoded peptides, polypeptides, and proteins on DNA
A novel method for displaying proteins and peptides is disclosed in which individual proteins or peptides remain associated with the DNA encoding them. Proteins...
US-1,001,1829 Peptides and uses thereof
The present disclosure relates to novel peptides and their uses including, proline-rich peptides that are useful for displaying a protein of interest at the...
US-1,001,1828 Non-disruptive DNA isolation from corn seeds
This invention relates to systems and process for isolating DNA from biological materials such as seeds while retaining a viable seed for further use. The seed...
US-1,001,1827 Method for isolating nucleic acids from a food sample
The method for isolating nucleic acids from a food sample comprising the following steps: a) obtaining a food enrichment culture; b) transferring a portion of...
US-1,001,1826 Parallel extraction of different biomolecules from formalin-fixed tissue
The present invention relates to a method of isolating/extracting in parallel various biomolecules, in particular nucleic acids and proteins, from the same...
US-1,001,1825 Method for activating a surface by increasing the hydrophilicity and/or for binding target structures
The invention relates to a method for activating a surface by increasing the hydrophilicity and/or for binding target structures, particularly selected from the...
US-1,001,1824 Beta-lactamases with improved properties for therapy
This invention relates to, in part, compositions of beta-lactamases and methods of using these enzymes in, for example, gastrointestinal tract (GI tract)...
US-1,001,1823 Engineered botulinum neurotoxin
The present invention provides a novel modified BoNT/E catalytic domain and methods of use thereof. In one embodiment, the light chain residue 224, or a residue...
US-1,001,1822 Phytase having improved thermostability
A phytase having improved thermostability is disclosed. The phytase has a modified amino acid sequence of SEQ ID NO: 2, wherein the modification is one of...
US-1,001,1821 Melleolide-biosynthesis gene cluster and its applications
The present invention relates to the production of hydroxylated protoilludenes and/or sesquiterpenoid protoilludene-type aryl esters using newly identified...
US-1,001,1820 Adipose stromal vascular fraction cell constructs
Three-dimensional tissue constructs are described, which may be created by isolating adipose-derived stromal vascular fraction (SVF) cells, plating the cells...
US-1,001,1819 Culture medium for preparing neural stem cells and use thereof
Provided are a culture medium for preparing neural stem cell and use thereof, the culture medium for preparing neural stem cell comprising: a basic culture...
US-1,001,1818 Method for in vitro oocyte maturation
Methods are provided for in vitro maturation (IVM) of bovine oocytes that include steps of (a) pre-culturing bovine germinal vesicle (GV) oocytes in the...
US-1,001,1817 Cell rolling separation
The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A...
US-1,001,1816 Method for cell culture
A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I.alpha.I (inter-alpha...
US-1,001,1815 Method to sporulate coccidial oocysts purified from animal faeces, sporulated oocysts obtained with this method...
The invention pertains to a method to sporulate coccidial oocysts purified from animal faeces (5), the method comprising providing the purified oocysts as a...
US-1,001,1814 Salt formulations for the fermentation of marine microorganisms
Growth medium are disclosed for use in fermenting a marine microorganism. The medium comprise Potassium, Calcium, Strontium, Borate and Fluoride at specific...
US-1,001,1813 Methane oxidation methods and compositions
The disclosure provides devices and methods to produce electrical energy from microorganisms capable of metabolizing methane.
US-1,001,1812 Culture control method, cell culture apparatus, and apparatus for evaluation of cellular characteristics
This invention provides a culture control method and a cell culture apparatus that enable stable cell culture by regulating shear stress to be applied to cells...
US-1,001,1811 Cell seeding device and method
Described is a device comprising an anchor, a tray including a well adapted to receive the anchor, and a cover adapted to engage the tray and cover the well....
US-1,001,1810 Method for producing beer-taste beverage
A method for producing a beer-taste beverage characterized in that the method includes adding a hop selected based on hop plant age; and a method for adjusting...
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