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Patent # Description
US-1,001,6491 Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
The invention relates to the discovery of novel soluble neutral active Hyaluronidase Glycoproteins (sHASEGPs), methods of manufacture, and their use to...
US-1,001,6490 Multiple-enzyme nanocomplexes
Provided are nanocomplexes having at least two different enzymes and a polymeric network anchored to at least one of the enzymes. In some embodiments, the...
US-1,001,6489 Methods and compositions for treating diseases
The present invention provides methods and compositions comprising ALDH2 in the treatment of a patient with toxicity resulting from ALDH2 deficiency. The...
US-1,001,6488 Nitric oxide synthase nanoparticles for treatment of vascular disease
A sustained-release composition for stimulating endothelial cell growth including a nitric oxide synthase within a nanoparticle comprising a biocompatible...
US-1,001,6487 Process for purifying lactoferrin from milk and products thereof
The invention provides a process for purifying lactoferrin from milk, the process comprising subjecting the milk to filtration to separate it into a retentate...
US-1,001,6486 Methods and compositions using AMPK activators for pharmacological prevention of chronic pain
Methods and compositions using a combination of adenosine monophosphate protein kinase (AMPK) activators for treating pain such as post-surgical pain or...
US-1,001,6485 Methods and use of growth hormone supergene family protein analogs for treatment of radiation exposure
Methods and compositions for the use of long-acting hematopoietic factor protein analogs for accelerating hematopoietic recovery in subjects who have been or...
US-1,001,6484 Methods of treating lung cancer
Methods of treating cancers comprising FGFR1 gene amplification are provided. In some embodiments, the methods comprise administering a fibroblast growth factor...
US-1,001,6483 Methods for preventing or treating certain disorders by inhibiting binding of IL-4 and/or IL-13 to their...
The present disclosure relates to methods of treating, ameliorating or preventing a disorder comprising administering a therapeutically effective amount of a...
US-1,001,6482 Insulin independence among patients with diabetes utilizing an optimized hamster REG3 gamma peptide
Embodiments of the present invention provide for novel therapies, pharmaceutical compositions and methods for insulin independence utilizing a new optimized...
US-1,001,6481 Sensation-improving agent
An object of the present invention is to provide a safety sensation-improving agent that can improve dulled peripheral sensations through daily ingestion or...
US-1,001,6480 Peptide-based methods for treating pancreatic cancer
Methods for treating a subject for pancreatic cancer via administration of small anti-inflammatory peptides are disclosed. The peptides may be administered in...
US-1,001,6479 Dosing regimens for echinocandin class compounds
The invention features pharmaceutical compositions, methods, and kits featuring dosing gimens and oral dosage formulations for administration of echinocandin...
US-1,001,6477 Natural composition
A medicinal compound includes ingredients combined in proportions substantially including: a portion of Turraea Heterophylla; a portion of Ginger; a portion of...
US-1,001,6476 Nutrient combinations for affecting an aging process
A composition comprising an effective amount of a combination of mitochondrial nutrients sufficient to affect mitochondrial function. A method of affecting an...
US-1,001,6475 Composition for preventing, improving, or treating immune diseases comprising natural extracts as active...
The present invention provides a composition for preventing, improving, or treating Th1-mediated immune diseases or Th2-mediated immune diseases, an...
US-1,001,6474 Plant extract, compositions containing same, method of extraction and uses thereof
An extract from leaves of mulberry is disclosed. The extract has an IC.sub.50 value sufficient to inhibit .alpha.-glucosidase I. The extract may comprise 5-40%...
US-1,001,6473 Method, apparatus, and kit for the pulsing treatment of neurodegenerative diseases and impairments
A method, apparatus and kit have been discovered which utilize pulsed odorants, drugs, medicaments, and combinations thereof to treat diseases, symptoms of...
US-1,001,6472 Methods of mitigating the negative effects of resistance exercise
Methods for inhibiting exercise-induced production of cortisol, exercise-induced production of myeloperoxidase, exercise-induced production of creatine kinase,...
US-1,001,6471 Solid pharmaceutical compositions of brown algae
Described herein are solid pharmaceutical compositions of brown algae extracts and methods for making solid pharmaceutical compositions of brown algae extracts....
US-1,001,6470 Oncolytic adenoviruses for cancer treatment
The invention relates to an oncolytic adenovirus for the treatment of cancer, containing a human DNA sequence isolating a promoter conferring selective...
US-1,001,6469 Composition comprising antifungal agents for treating vulvovaginitis and vaginosis
Disclosed is a method of treating vaginosis with a composition having Steroidobacter denitrificans YH1 (KCTC18345P) and Lactobacillus crispatus YH2 (KCTC18346P)...
US-1,001,6468 Method and compositions for treating cancer using probiotics
The subject invention pertains to probiotic compositions and methods of treating hepatocellular carcinoma (HCC) using the probiotic compositions. The probiotic...
US-1,001,6467 Formulations of viable cells for oral delivery
This invention relates to solid formulations for the oral delivery of live microbial cells which comprise dried viable cells and small amounts of a bile acid...
US-1,001,6466 Topical medicament for skin and mucosal injuries associated with Epidermolisis bullosa
A composition and method for treating Epidermolisis bullosa (EB), comprising: applying to skin or mucosal surfaces of a patient in need of treatment for EB a...
US-1,001,6465 Cured gel and method of making
A cured non-polymeric gel including a plurality of non-polymeric cross-links. The non-polymeric cross-links result from curing an oil or oil composition at...
US-1,001,6464 Amniotic membrane hydrogel and methods of making
The present invention provides compositions and methods for wound healing and tissue regeneration. The compositions of the present invention comprise amniotic...
US-1,001,6463 Treatment of pulmonary arterial hypertension with prostacyclin-treated endothelial progenitor cells
The current application is directed to a method for treating pulmonary arterial hypertension (PAH), comprising: providing isolated endothelial progenitor cells...
US-1,001,6462 Adult cardiac stem cell population
The present invention relates to the identification, isolation, expansion and characterization of a specific type of multipotent adult cardiac stem cell. These...
US-1,001,6461 Apparatus and process for growing a heart valve in three-dimensions
The present invention relates to a heart valve and, more particularly, to a mold and process shaping and securing cells and tissue layers as they are grown in...
US-1,001,6460 Method of inducing cellular growth and materials for use therewith
The present invention relates generally to a method of producing a population of cells and materials for use therewith. More particularly, the present invention...
US-1,001,6459 Platelet-rich plasma derived from human umbilical cord blood
A platelet-rich plasma composed of aseptically recovered umbilical cord blood is provided, as well as uses thereof.
US-1,001,6458 p53 silenced endothelial progenitor cells for diabetes
The invention provides, inter alia, methods for treating vascular deficiencies, including those in diabetic subjects, by transplanting endothelial progenitor...
US-1,001,6457 Composites of hydroxyapatite and calcium carbonate and related methods of preparation and use
Carbonated calcium phosphate compositions and methods of preparation, affording enhanced biophysical properties.
US-1,001,6456 Methods for treating acne vulgaris
Methods for treating acne vulgaris include providing a solution having a peroxide compound, the solution having an antimicrobial effect for reducing bacteria...
US-1,001,6455 Method of preventing or treating influenza with oxidative reductive potential water solution
Provided is a method for preventing or treating influenza by administering a therapeutically effective amount of an oxidative reduction potential (ORP) water...
US-1,001,6454 Silane-containing moisture-curable tissue sealant
A tissue sealant that includes the reaction product of (a) a polyol; (b) a polyisocyanate; and (c) an alkoxy silane having the formula: ...
US-1,001,6453 In vitro bio-reactor circuit
Embodiments of the invention provide bio-reactor circuits for in vitro research applications. One embodiment provides a bio-reactor circuit comprising at least...
US-1,001,6452 Fibromodulin formulation for reducing corneal scarring
A formulation for reducing corneal scarring and related eye conditions, is disclosed. The formulation comprises an effective amount of fibromodulin and can be...
US-1,001,6451 Nucleic acid nanoparticles and uses therefor
The present invention provides nanoparticle compositions including one or more nucleic acids. The present invention achieves delivery (particularly transdermal...
US-1,001,6450 Anti-glycation methods and compositions
The present invention comprises compositions that provide anti-glycation activity comprising a mineral extract composition or a mogroside/mineral extract...
US-1,001,6449 Pharmaceutical compositions
Described herein are pharmaceutical compositions comprising a LMWH preparation having at least one chain having a glycol split uronic acid residue (UG) in the...
US-1,001,6448 Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity
The present invention provides novel pyrimidine and pyridine compounds according to Formula (I), Formula (II), Formula (III), Formula (IV) and Formula (V) their...
US-1,001,6447 Pharmaceutical composition having improved content uniformity
This present invention relates to pharmaceutical compositions comprising cyclophosphamide alone and/or in combination with one or more pharmaceutical active...
US-1,001,6446 Compositions for oral administration of zoledronic acid or related compounds for treating Paget's disease of bone
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, such as zoledronic acid in an acid or a salt form, or in a molecular...
US-1,001,6445 Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain...
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
US-1,001,6444 Molecules for bone tissue regeneration
The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts thereof: (I) wherein Ri is selected from an SCN-- group or is an...
US-1,001,6443 Treatment of allergic rhinitis using a combination of mometasone and olopatadine
The present invention relates to a method of treating allergic rhinitis in a subject (e.g., a human) in need thereof comprising nasally administering to the...
US-1,001,6442 Estrogen compositions for vaginal administration
Pharmaceutical gel compositions containing estrogen for vaginal administration, as well as a method of making the same, are disclosed.
US-1,001,6441 Prostaglandin conjugates and derivatives for treating glaucoma and ocular hypertension
Prostaglandin conjugates and derivatives and methods for their use to treat glaucoma and/or lower intraocular pressure are disclosed. Additionally, ophthalmic...
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