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Patent # Description
US-1,001,7480 Compounds having a selective PDE4D inhibiting activity
Compounds of formula (I), wherein Z=cyclopentyl. cyclopropylmethyl, --CH.sub.3; R'.dbd.--CH.sub.3, CHF.sub.2, X=formula (II) (III) (IV) (V) Y=--CO;...
US-1,001,7479 Process to make non nucleosidal reverse transcriptase inhibitors (NNRTI) for the treatment of HIV
A chemical process that can form pharmaceutically acceptable medicaments NNRTI's for the treatment of HIV starting from thiotriazole compounds. The chemical...
US-1,001,7478 Inhibitors of ACK1/TNK2 tyrosine kinase
Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of Ack1 tyrosine kinase and their use in the treatment of...
US-1,001,7477 Janus kinase inhibitors and uses thereof
The present invention provides kinase inhibitors, such as compounds of Formula (I) and Formula (II). The compounds may covalently or non-covalently bind a...
US-1,001,7476 1,4-bis(3-aminopropyl)piperazine derivative and its use
The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or...
US-1,001,7475 Anti-vasculature and anti-tubulin combretastatin analogs for treatment of cancer
Combretastatins analog compounds and their pharmaceutically acceptable salts are presented, as well as pharmaceutical compositions comprising the combretastatin...
US-1,001,7474 Method of synthesizing (E)-1,2-di(pyridin-2-yl) ethene-1,2-diol
The method of synthesizing (E)-1,2-di(pyridine-2-yl)ethene-1,2-diol involves dimerization of 2-pyridinecarboxaldehyde (also referred to herein as...
US-1,001,7473 Method for preparing pentachloropyridine by utilizing DCTF rectifying short steaming residues
A method for preparing pentachloropyridine by utilizing DCTF rectifying short steaming residues, comprising the following steps: converting polymers in the...
US-1,001,7472 Hydrate of 2-isopropoxy-5-methyl-4-(piperidin-4-yl) aniline dihydrochloride, preparation method and use of the same
The present invention relates to 2-isopropoxy-5-methyl-4-(piperidin-4-yl) aniline dihydrochloride monohydrate and a preparation method of the same. The...
US-1,001,7471 Selective androgen receptor degrader (SARD) ligands and methods of use thereof
This invention provides novel indole, indazole, benzimidazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD)...
US-1,001,7470 Treatment for lipodystrophy
The present invention provides a therapeutic compound of formula (I) and their pharmaceutically acceptable salts for the prevention and treatment of...
US-1,001,7469 Stabilized compositions and methods of manufacture
A method for stabilization of potent alkanone-heterocyclic flavorants in dry powder form is provided. Coordination of alkanone-heterocyclic flavorants to...
US-1,001,7468 Substituted pyrrolidines as G-protein coupled receptor 43 agonists
The present invention is directed to a process for the preparation of aryl-pyrrolidine carboxylic acid derivative compounds which are useful in treating...
US-1,001,7467 Alkylbenzene hydroperoxide production using dispersed bubbles of oxygen containing gas
An apparatus for oxidation of a C.sub.8-C.sub.12alkylbenzene reactant to a C.sub.8-C.sub.12 alkylbenzene hydroperoxide product, the re-actor can comprise: a...
US-1,001,7466 Process for purifying astaxanthin and canthaxanthin
The present invention relates to a process for purifying the xanthophylls astaxanthin and canthaxanthin. The process comprises suspending the xanthophyll in an...
US-1,001,7465 Method for producing astaxanthin from astacin
The invention relates to a method for the non-stereoselective and also for the stereoselective synthesis of astaxanthin from astacin. For this purpose, a...
US-1,001,7464 Process for preparing cyclic alpha-keto alcohols from cyclic alpha-keto enols
The invention relates to a method for preparing a cyclic .alpha.-ketoalcohol, particularly a 6-hydroxycyclohexenone from a cyclic .alpha.-ketoenol, particularly...
US-1,001,7463 Inhibitors of deubiquitinating proteases
Disclosed are small molecule inhibitors of deubiquitinating enzymes (DUBs), and methods of using them. Certain compounds are selective for particular...
US-1,001,7462 Antimicrobial poly(guanylurea)s
A poly(guanylurea) (PGU), comprising the structure where a multiplicity of repeating units are connected by guanylurea groups. The repeating units comprise:...
US-1,001,7461 Method of making ligand functionalized substrates
Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.
US-1,001,7460 Compounds for promoting liposomal and cellular adhesion and compositions and methods of use thereof
The present application describes amphiphatic compounds like compound IIa below, compositions and methods for incorporating chemoselective and bio-orthogonal...
US-1,001,7459 .beta.-substituted .beta.-amino acids and analogs as chemotherapeutic agents and uses thereof
.beta.-Substituted .beta.-amino acids, .beta.-substituted .beta.-amino acid derivatives, and .beta.-substituted .beta.-amino acid analogs and (bio)isosteres and...
US-1,001,7458 Therapeutic tetrahydronaphthalene compounds
The invention relates to protein binding interacting/binding compounds and methods of identifying and using them. The invention further relates to...
US-1,001,7457 Continuous synthesis of isooctyl nitrate in a flow reactor
A process for synthesizing isooctyl nitrate in a continuous flow reactor comprises flowing a H2SO4-HNO3 mixture within a flow reactor, flowing isooctyl alcohol...
US-1,001,7456 Monomer and polymer and compensation film and optical film and display device
A monomer is represented by Chemical Formula 1: ##STR00001## wherein in Chemical Formula 1, X.sup.1 and X.sup.2 are independently O, C(.dbd.O), or...
US-1,001,7455 Enhanced production of fatty acid derivatives
Genetically engineered cells and microorganisms are provided that produce fatty alcohols from the fatty acid biosynthetic pathway, as well as methods of their use.
US-1,001,7454 Method of manufacturing BHCD and derivatives thereof
The present disclosure provides a method of manufacturing bis(2-hydroxyethyl) cyclohexane-1,4-dicarboxylate (BHCD) and derivatives thereof. The method includes...
US-1,001,7453 Pharmaceutically acceptable salts of fatty acids
The present disclosure provides pharmaceutically acceptable stable salt forms of 15-lipoxygenase products, such as 15-HETrE lysine salt, compositions comprising...
US-1,001,7452 Distillation process comprising at least two distillation steps to obtain purified halogenated carboxylic acid...
The present invention concerns a process for the obtention of a halogenated carboxylic halide having a reduced content of impurities, a fraction of the...
US-1,001,7451 Lactic acid extraction
A method for recovering lactic acid from an aqueous mixture including the steps of: providing an aqueous mixture including lactic acid and at least 5 wt. %...
US-1,001,7450 Method of operating a heavy ends column in an acetic acid production process
Method of operating a heavy ends column in an acetic acid production unit having a reaction section, a light ends recovery section including a light ends...
US-1,001,7449 Process for the recovery of carboxylic acid and wood treatment process
The present invention concerns a process for the recovery of carboxylic acid from a fraction comprising carboxylic acid and impurities, and a process for the...
US-1,001,7448 Process for hydrogenation of benzenepolycarboxylic acids and derivatives thereof
A process for ring hydrogenation of a benzenepolycarboxylic acid or derivative thereof, includes contacting a feed stream comprising the acid or derivative...
US-1,001,7447 Processes for making azelaic acid and derivatives thereof
Methods of making azelaic acid, or derivatives thereof, from unsaturated monobasic acids or esters are disclosed herein. In some embodiments, the unsaturated...
US-1,001,7446 Acid/salt separation
The invention provides a method for preparing a carboxylic acid, which method includes the steps of providing magnesium carboxylate, wherein the carboxylic acid...
US-1,001,7445 Deuterated idebenone
The present invention in one embodiment provides a compound of Formula I:(I), or a pharmaceutically acceptable salt thereof, wherein the variables shown in...
US-1,001,7444 Method for the purification of natural vanillin
The invention relates to a natural vanillin, which is in the form of an amorphous solid of which the color, in ethanolic solution at 10% by weight, is less than...
US-1,001,7443 Optimized separation technique for work-up of homogeneously catalysed hydroformylation mixtures
The invention relates to a method for producing alcohols by homogeneously catalyzed hydroformylation of olefins to aldehydes and subsequent hydration of the...
US-1,001,7442 Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of...
The present invention relates to a polyphenol derivative of the stilbenoid family, namely trans-3,5,4'-trihydroxybibenzyl, also known as dihydro-resveratrol, as...
US-1,001,7441 Direct anti-markovnikov addition of acids to alkenes
A method of making an anti-Markovnikov addition product, comprises reacting an acid with an alkene or alkyne in a dual catalyst reaction system to the exclusion...
US-1,001,7440 Method for controlling cleavage of hydroperoxides of alkylaromatic hydrocarbons
A method of producing phenol and acetone can include: alkylating benzene with a C.sub.2-6 alkyl source in the presence of a zeolite catalyst to produce a...
US-1,001,7439 Process for the isolation of reaction products from sugar alcohol or anhydrosugar alcohol hydrogenolysis...
A method of isolating and purifying a product of sugar alcohol or anhydrosugar alcohol hydrogenolysis from a reaction mixture containing sorbitans,...
US-1,001,7438 Method and device system for producing dimethyl oxalate through carbonylation of industrial synthesis gas and...
A method and a device system for producing dimethyl oxalate through high-pressure carbonylation of industrial synthesis gases and producing ethylene glycol...
US-1,001,7437 Method for purifying fluorinated hydrocarbon compound
The present invention is a method for purifying a fluorohydrocarbon compound comprising bringing a crude saturated fluorohydrocarbon compound having 4 or 5...
US-1,001,7436 Method of making 1,1,1,2,3-pentachloropropane
The present invention provides a method of making 1,1,1,2,3-pentachloropropane comprising: (1) utilizing 1,1,1,3-tetrachloropropane as a raw material and ...
US-1,001,7435 Process for the preparation of a phenylindan compound
The present invention refers to a process for producing 5-[4-(2-hydroxy-2-methyl)-1-oxo-prop-1-yl]-3-[4-(2-hydroxy-2-methyl)-1-ox- ...
US-1,001,7434 Membrane-based gas separation processes to separate dehydrogenation reaction products
Gas separation processes are provided for separating dehydrogenation reaction products from a raw gas stream to recover hydrocarbons, specifically olefins, such...
US-1,001,7433 Transalkylated cyclohexylbenzyl and biphenyl compounds
Processes for selectively alkylating and/or dealkylating one ring of cyclohexylbenzyl and/or biphenyl compounds are provided. Such selective alkylation and/or...
US-1,001,7432 Alkane oxidative dehydrogenation and/or alkene oxidation
The invention relates to a process of the oxidative dehydrogenation of an alkane containing 2 to 6 carbon atoms and/or the oxidation of an alkene containing 2...
US-1,001,7431 Process for co-producing C3 olefins, iC4 olefins, nC4 olefins and diolefins, and/or C5 olefins and diolefins
Processes and systems for producing olefins, including: dehydrogenating a first n-alkane to produce a first effluent; and dehydrogenating at least one of a...
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