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Patent # Description
US-1,007,7258 Substituted pyrimidine compounds as phosphatidylinositol 3-kinase delta inhibitor and use thereof
The present invention belongs to the field of medicinal chemistry, and relates to substituted pyrimidine compounds as phosphatidylinositol 3-kinase (PI3K)...
US-1,007,7257 Aziridinated triglycerides and polymers formed therefrom
Various embodiments disclosed relate to aziridinated triglycerides and polymers formed therefrom. In various embodiments, the present invention provides an...
US-1,007,7256 Synthetic route to anti-viral agents
The invention provides methods of synthesizing a viral protease inhibitor in high yield, without using expensive catalysts or challenging reaction conditions.
US-1,007,7255 Synthesis of chiral 2-(1H-indazol-6-yl)-spiro[cyclopropane-1,3'-indolin]-2'-ones
The present invention is directed to novel synthetic methods for preparing cyclopropyl indolinone compound represented by Structural Formula (A): (A) or its...
US-1,007,7254 Tetrazolinone compound and use thereof
A tetrazolinone compound represented by formula (1) ##STR00001## wherein E represents the following group E16; ##STR00002## Y represents --O--CH.sub.2--;...
US-1,007,7251 Process for the synthesis of Dabigatran Etexilate and its intermediates
The present invention describes an improved process for the preparation of Dabigatran Etexilate (Formula-VII) or it's pharmaceutically acceptable salt for the...
US-1,007,7250 Antifungal compound process
The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new...
US-1,007,7249 Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzal- dehyde
Disclosed herein are processes for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzal- dehyde (also referred to herein as...
US-1,007,7248 Form of imazapyr, a process for its preparation and use the same
The present invention describes the crystalline form of imazapyr of formula (I), the crystal preparation process, the analyses of the crystal through various...
US-1,007,7247 Tricyclic spiro compound
A medicinal agent for the prevention and/or treatment of diseases caused by EP.sub.4 receptor activation. A compound having antagonistic activity against the...
US-1,007,7246 Tricyclic prodrugs
Prodrugs (I) and (Ia) of galiellactone, and derivatives thereof, are provided by reacting the parent compound, e.g. galiellactone, with a thiol. Such drugs may...
US-1,007,7245 KCNQ potassium channel agonists, method of preparation and method of use thereof
The present invention provides a compound represented by general formula I or a pharmaceutical acceptable salt thereof, the preparation method therefor and the...
US-1,007,7244 Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
A method to detect the presence of amount of at least one molecule in a sample which employs a derivative of luciferin or a derivative of a fluorophore is...
US-1,007,7243 Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
Provided herein are compounds of formula (I): ##STR00001## and pharmaceutical compositions thereof, useful for the treatment of disorders mediated by...
US-1,007,7242 Convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction
Methods of synthesizing the angiotensin II receptor antagonist telmisartan in high yield and purity are provided. The methods involve the coupling of two...
US-1,007,7241 Tetrahydro-benzoimidazolyl modulators of TGR5
The present invention comprises compounds of Formula (I). ##STR00001## wherein: R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, X,...
US-1,007,7240 Compositions and methods for modulating farnesoid X receptors
The present invention relates to compounds of Formula I, ##STR00001## a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid...
US-1,007,7239 Crystalline forms of a hepatitis B antiviral agent
This disclosure provides crystalline forms of a hepatitis B antiviral agent, and methods of making and using these forms.
US-1,007,7238 Small molecule LFA-1 inhibitors
The present invention relates to novel compounds which are capable of inhibiting the interaction of LFA-1 with its counter ligands.
US-1,007,7237 Oxindole derivatives, preparation thereof and therapeutic use in the treatment of AMPK-related diseases
The present invention relates to compounds corresponding to formula (I). Process for the preparation thereof and therapeutic use thereof. The compounds are...
US-1,007,7236 Azacyclic constrained analogs of FTY720
Small molecules comprised of azacyclic constrained analogs of FTY720 are provided. Formulations and medicaments are also provided that are directed to the...
US-1,007,7235 Integrated process for the production of formaldehyde-stabilized urea
The present disclosure relates to an integrated process for the production of formaldehyde-stabilized urea, starting with producing synthesis gas and including...
US-1,007,7233 Poly-cyanostilbene macrocycles
The present disclosure concerns synthesis and anion binding features of poly-cyanostilbene macrocycles of Formula (I): ##STR00001##
US-1,007,7232 Cyclic cationic lipids and methods of use
The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel cationic lipids and...
US-1,007,7231 Functionalized fluoropolymers and electrolyte compositions
Provided herein are functionally substituted fluoropolymers suitable for use in liquid and solid non-flammable electrolyte compositions. The functionally...
US-1,007,7230 Ester-based compound, composition comprising the same, method for preparing the same and resin composition...
The present invention relates to an ester-based plasticizer composition, a method for preparing the same and a resin composition comprising the same. The...
US-1,007,7229 Ether-containing monoester compound and use thereof
A compound of the present invention is represented by the general formula (1) and has a 40.degree. C. kinetic viscosity (v) that satisfies 4 ...
US-1,007,7228 Ferrocene-based compounds and palladium catalysts based thereon for the alkoxycarbonylation of ethylenically...
The invention relates to a compound of formula (I) ##STR00001## where R.sup.1, R.sup.2, R.sup.3, R.sup.4 are each independently selected from ...
US-1,007,7227 Method for synthesizing an alkenoic acid
There is provided a method for synthesizing an alkenoic acid, in particular acrylic acid comprising the step of oxidizing an alkenyl alcohol in the presence of...
US-1,007,7226 Process for production of adipic acid from 1,6-hexanediol
Processes are disclosed for the conversion of 1,6-hexanediol to adipic acid employing a chemocatalytic reaction in which 1,6-hexanediol is reacted with oxygen...
US-1,007,7225 Synthesis of intermediate for treprostinil production
The compound according to Formula I is an intermediate in the synthesis of prostacylin analogs. The present invention provides an efficient method for...
US-1,007,7224 Production of 1,5-pentanediol via upgrading of tetrahydrofurfuryl alcohol
A method of making 1,5-pentanediol from tetrahydrofurfural alcohol. The method includes the steps of dehydrating tetrahydrofurfural alcohol (THFA) to...
US-1,007,7223 Method for producing monoethylene glycol
Process for preparing monoethylene glycol (MEG) by metal-catalyzed reaction of a dialkyl oxalate of the formula I ##STR00001## where R.sup.1 and R.sup.2 are...
US-1,007,7222 Process for the preparation of ethylene glycol from sugars
A process for the preparation of ethylene glycol comprising the steps of pyrolyzing a monosaccharide and hydrogenating the product composition in the presence...
US-1,007,7221 Composition comprising HF and E-3,3,3-trifluoro-1-chloropropene
An azeotropic or quasi-azeotropic composition including hydrogen fluoride, E-3,3,3-trifluoro-1-chloropropene and optionally one or more (hydro)halogen-carbon...
US-1,007,7220 Aromatics production process
In a process for producing para-xylene, at least one feed comprising C.sub.6+ aromatic hydrocarbons is supplied to a dividing wall distillation column to...
US-1,007,7219 Continuous mixing reactor and method of use
A continuous mixing reactor has an outer shell having a cylindrical portion with a central section and two opposite conical end sections; a circulation tube...
US-1,007,7218 Process for converting a heavy feed into middle distillate
The present invention describes a process for the conversion of a heavy feed which can be used to improve the selectivity for middle distillate. The process...
US-1,007,7217 Strengthened composite products and methods for making and using same
The disclosure provides strengthened products, including strengthened fibrous composite products and methods for making and using same and strengthened...
US-1,007,7216 Soluble fertilizer formulation and method for use thereof
A fertilizer including a growth enhancing component, in at least one example a co-polymer of fulvic acid and poly-metallic humates is present in the amount of...
US-1,007,7215 Fertilizer having reduced biuret content
The present invention discloses the use of a lignin compound to prepare a urea fertiliser having reduced biuret content.
US-1,007,7214 Sintered porous material and filter element using same
A sintered porous material with stronger corrosion resistance comprising three elements Ti, Si and C which constitute at least 90% of the weight of the porous...
US-1,007,7213 Method for fabricating an alumina body having nano-sized open-cell pores that are stable at high temperatures
A method for fabricating an alumina body having nano-sized open-cell pores, the alumina body is formed from .alpha.-Al.sub.2O.sub.3 and Al(OH).sub.3. The...
US-1,007,7212 Cement compatible water-based drilling mud compositions
A water-based drilling mud for use in cementing operations includes water, LASSENITE.RTM. pozzolan-based additive, a heavy-weight additive, a viscosifier, a...
US-1,007,7211 Cement grinding aids prepared with waste antifreeze
It discloses cement grinding aids prepared with waste antifreeze which comprises the following components in parts by weight: 20-75 parts of pretreated waste...
US-1,007,7210 Encapsulated lightweight polymer aggregates
A lightweight aggregate for use in forming lightweight cementitious mixes and/or concrete is formed by encapsulating a plurality of hydrophobic polymer...
US-1,007,7209 Glazing unit comprising a hydrophilic layer having an improved scratch resistance
A glazing unit includes a hydrophilic layer including a polyurethane network incorporating bis-urea functions. Furthermore, a process for manufacturing this...
US-1,007,7208 Glass article and method for forming the same
A method includes forming a glass article. The glass article includes a core and a clad adjacent to the core. The core includes a first glass composition. The...
US-1,007,7207 Optical coating method, apparatus and product
This disclosure is directed to an improved process for making glass articles having optical coating and easy-to clean coating thereon, an apparatus for the...
US-1,007,7206 Methods of etching glass substrates and glass substrates
A method of forming a glass substrate includes providing a glass substrate having alumina, translating a pulsed laser beam on the glass substrate to form one or...
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