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Patent # Description
US-1,008,7459 Modulation of seed vigor
The present invention provides a polynucleotide which enables the modulation of the seed vigor, and in particular enhances the seed vigor, and more particularly...
US-1,008,7458 Manipulating BS1 for plant seed yield
The present invention provides methods for increasing plant seed yield or seed size through reduced expression of a BS1 gene. Also provided are plants with...
US-1,008,7457 Plant with enhanced growth and method for producing the same
A method for producing a plant with enhanced growth is provided including a step of introducing a gene encoding a chimeric myosin XI protein into a host plant...
US-1,008,7456 DGAT genes for increased seed storage lipid production and altered fatty acid profiles in oilseed plants
Polynucleotide sequences encoding diacylglycerol acyltransferase genes and the use of these acyltransferases for increased seed storage lipid production and...
US-1,008,7455 Wheat with reduced lipoxygenase activity
A series of independent human-induced non-transgenic mutations found at one or more of the Lpx genes of wheat; wheat plants having these mutations in one or...
US-1,008,7454 Method to develop high oleic acid soybeans using conventional soybean breeding techniques
The present invention is directed to a soybean plant with mutations in FAD2-1A and FAD2-1B. Moreover, the present invention is directed to seeds from said...
US-1,008,7453 Modified diatoms for biofuel production
The invention provides engineered diatoms and methods of producing oil using diatoms. The invention also provides methods of modifying the lipids quantity...
US-1,008,7452 Method for agrobacterium mediated transformation of cambial meristematic plant cells to produce recombinant protein
Plant cells express a target protein, a production method thereof, and a method of producing a target protein using the same are disclosed. The plant cells have...
US-1,008,7451 Live bacterial vectors for prophylaxis or treatment
A live bacterium, having a DNA construct stabilized against transduction of other bacteria, having a promoter sequence and encoding a fusion peptide, comprising...
US-1,008,7450 Engineered yeast for production of enzymes
Described herein is an engineered Kluyveromyces marxianus cell, the cell comprising in its genome: (i) two different nucleic acid molecules that each contain a...
US-1,008,7449 Pharmaceutical composition for treating chronic kidney disease
This invention is related to a therapeutic agent for treating chronic kidney disease comprising a substance which inhibits the enzymatic activity of NNMT or...
US-1,008,7448 Synthetic lethality in cancer
There is described herein compounds, compositions and methods for inducing synthetic lethality in a cancer cell(s).
US-1,008,7447 Antiproliferative agent
The invention provides an antibody specific to the ANGPTL4 protein capable of neutralizing proliferation and methods of making and using the same. The antibody...
US-1,008,7446 Methods and compositions to inhibit metastasis and to treat fibrosis and to enhance wound healing
Methods and compositions are provided for inhibiting or treating metastasis based on discoveries regarding Kif19 and Cep192. Methods and compositions are...
US-1,008,7445 Modifications for antisense compounds
The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from...
US-1,008,7444 MicroRNA composition for the treatment of neuroblastoma
Certain embodiments are directed to methods of identifying neuroblastoma differentiation-inducing compounds or agent and their use in treating neuroblastoma.
US-1,008,7443 Compositions and methods for modulating neuronal excitability and motor behavior
The invention is directed to compositions and methods for treating or reducing the likelihood of the development of epilepsy in an individual. The method...
US-1,008,7442 Polycation-functionalized nanoporous silicon carrier for systemic delivery of gene silencing agents
Disclosed are methods and compositions containing functionalized nanoporous silicon particles, useful in a variety of diagnostic and/or therapeutic regimens for...
US-1,008,7441 In vivo gene silencing by chemically modified and stable siRNA
The present invention provides compositions for RNA interference and methods of use thereof. In particular, the invention provides small interfering RNAs...
US-1,008,7440 Device for preparation and analysis of nucleic acids
An integrated "lab-on-a-chip" microfluidic device performs nucleic acid sample preparation and diagnostic analysis from test samples containing cells and/or...
US-1,008,7439 Rapid methods for the extraction of nucleic acids from biological samples
The invention is directed to compositions and methods for rapidly and efficiently extracting nucleic acids and/or targeted nucleic acids sequences from...
US-1,008,7438 Solid-core ring-magnet
A solid-core ring-magnet having one or more cavities is provided. The magnet can have an overall cylindrical shape or a rectangular-prism shape. In either case,...
US-1,008,7437 Method for nuclei storage
A method of performing data management in a high-speed data environment. The method includes collecting time-series information including multiple data types...
US-1,008,7436 Electrophysiologically mature cardiomyocytes and methods for making same
Methods to prepare electrophysiology mature cells from immature cells are provided, without the need for genetic manipulation.
US-1,008,7435 Methods and compounds for reducing threonyl-tRNA synthetase activity
The invention includes, in part, methods and compounds for treating diseases and conditions characterized by elevated threonyl-tRNA synthetase (TARS) activity,...
US-1,008,7434 Methods for extracting and purifying non-denatured proteins
Materials and methods for extracting and purifying proteins are provided. For example, the materials and methods provided herein can be used for extracting and...
US-1,008,7433 Beta-lactamases with improved properties for therapy
This invention relates to, in part, compositions of beta-lactamases and methods of using these enzymes in, for example, gastrointestinal tract (GI tract)...
US-1,008,7432 Methods for the manufacture of proteolytically processed polypeptides
The present invention relates to a novel proteolytically active polypeptide and various uses of the polypeptide (and others) in screening and manufacturing...
US-1,008,7431 Methods of generating nucleic acid fragments
Provided herein are methods of using a Cas1 polypeptide to generate nucleic fragments from a DNA substrate. These methods may be performed in vitro or in vivo....
US-1,008,7430 Factors for the production and accumulation of polyunsaturated fatty acids (PUFAS) derived from PUFA synthases
Disclosed are novel enhancing factor proteins of the PUFA synthase systems, nucleic acid molecules encoding the same, recombinant nucleic acid molecules and...
US-1,008,7429 STEP-derived peptide for brain injury treatment
A novel peptide sequence that is a modified derivative of a neuron-specific tyrosine phosphatase is shown and described. Specifically, the novel peptide...
US-1,008,7428 Acyl-ACP thioesterase
An acyl-ACP thioesterase consisting of an amino acid sequence of the 115.sup.th to 274.sup.th amino acids set forth in SEQ ID NO: 1; an acyl-ACP thioesterase...
US-1,008,7427 Glycosyltransferase gene and use thereof
Provided is a polynucleotide encoding a protein that exhibits activity for transferring a sugar to a hydroxyl group at position 7 of a flavone, particularly...
US-1,008,7426 Polynucleotides encoding cyclohexanone monooxygenases
The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods...
US-1,008,7425 Chimeric enzymes for conversion of lignin-derived chemicals
Disclosed herein are enzymes useful for the dealkylation of aromatic substrates, including the conversion of guaiacol or guaethol to catechol. Methods of...
US-1,008,7424 Method for adjusting expression of hydroxymethylglutaryl CoA reductase using bZIP-type transcription factor,...
The present invention provides a method enhancing the polyisoprenoid biosynthesis pathway. Also provided are an isoprenoid-producing plant having an overall...
US-1,008,7423 Method for harvesting expression products
The present invention provides methods and systems for recovering an essentially cell-associated expression product from a host cell comprising (a) culturing...
US-1,008,7422 Organ chips and uses thereof
Disclosed herein are organ chips that can be individually used or integrated together to form different microphysiological systems, e.g., for use in cell...
US-1,008,7421 Stem cell suspension
The present invention provides a mammalian stem cell suspension containing mammalian stem cells and at least one polysaccharide such as trehalose, and the like;...
US-1,008,7420 Expansion of adult stem cells in vitro
Disclosed are methods for manipulating and expanding stem cell populations, including adult stem cells, the cells produced by such methods, and various protein...
US-1,008,7419 Method for producing differentiated cells
The present invention has an object of providing a method for producing specific cells by amplifying cells in a desired differentiation stage. The present...
US-1,008,7418 Methods for inducing the differentiation of blood monocytes into functional dendritic cells
Methods are provided for treating blood monocytes to produce functional antigen presenting dendritic cells. An extracorporeal quantity of a subject's blood is...
US-1,008,7417 Three-dimensional model of human cortex
Disclosed herein are methods for differentiation of neuronal cells from stem cells, which produce a three-dimensional model of the neocortex structure. In some...
US-1,008,7416 Culturing pluripotent stem cells
A method for culturing and maintaining a pluripotent stem cell in an undifferentiated state is provided. The method comprises culturing the pluripotent stem...
US-1,008,7415 Cell tray and device, method and system for producing cell structure
Provided are: a cell tray provided with a concave part for supporting a cell aggregate and a hole formed on the bottom of the concave part; and a device for...
US-1,008,7414 Unitary 3D culture device
A continuous device for culturing mammalian cells in a three-dimensional structure for the transplantation or implantation in vivo is described. The culturing...
US-1,008,7413 Thin film cell encapsulation devices
Thin film devices, e.g., multilayer thin film devices, that encapsulate cells for transplantation into a subject are provided. Also provided are methods of...
US-1,008,7412 In vitro propagation of Babesia microti
A method for continuous in vitro propagation of Babesia microti and microti-like species is disclosed. The method comprises incubating B. microti in culture...
US-1,008,7411 Methods and apparatus for separating ethanol from fermented biomass
A method for separating ethanol from fermented biomass is provided. Fermented biomass that is rich in ethanol is used directly as packing material in a...
US-1,008,7410 Cell culturing device, culturing vessel, and holding vessel
In culture vessels for producing biological samples, it is possible to prevent decrease in a temperature at the time of taking out the culture vessels from an...
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