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Patent # Description
US-1,009,8966 Complex particles for delivering nitric oxide, method of producing the same, and application of the same
The present invention relates to complex particles for delivering nitric oxide, method of producing the particles, and application of the particles, and more...
US-1,009,8965 Compounds and compositions for the treatment of ocular disorders
The disclosure describes prodrugs and derivatives of prostaglandins, carbonic anhydrase inhibitors, kinase inhibitors, beta-adrenergic receptor antagonists and...
US-1,009,8964 Inclusion complexes and methods for making the same
The invention provides novel formulations comprising a stable inclusion complex of tributyrin and a cyclodextrin. In one particular embodiment, the formulation...
US-1,009,8963 Weekly dosing regimens for anti-CD30 VC-PAB-MMAE antibody drug-conjugates
Methods for the treatment of CD30-expressing cancers are provided. The methods comprise administering to a subject in need thereof a weekly dose of from about...
US-1,009,8962 Glycosaminoglycan derivative and method for producing same
The present invention provides a glycosaminoglycan derivative in which a group derived from glycosaminoglycan and a group derived from a physiologically active...
US-1,009,8961 Hyaluronic acid composition
An injectable hyaluronic acid composition including a hyaluronic acid; a local anesthetic selected from the group of amide and ester type local anesthetics or a...
US-1,009,8960 Polymer conjugate
The present invention concerns a conjugate of a domain I .beta.2GP1 polypeptide with a water-soluble polymer, wherein the polymer is bound via two cysteine...
US-1,009,8959 Method for synthesis of reactive conjugate clusters
Provided herein are improved methods for the synthesis of reactive conjugate clusters and intermediates used in such methods. In particular, improvements are...
US-1,009,8958 Delivery of oligonucleotide functionalized nanoparticles
The present invention relates to compositions and methods for delivering an oligonucleotide-functionalized nanoparticle.
US-1,009,8957 Long-acting polymeric delivery systems
Compositions comprised of a delivery vehicle or delivery system and an active agent dispersed within the delivery vehicle or system, wherein the delivery...
US-1,009,8956 Stabilizing agent for pharmaceutical proteins
A method for stabilizing a human blood protein or human blood plasma protein with a molecular weight of >10 KDa by adding melezitose to a solution comprising...
US-1,009,8955 Pharmaceutical formulations containing lipoic acid derivatives
Pharmaceutical formulations containing lipoic acid derivatives and ion pairs thereof are described. The pharmaceutical formulations are useful in the treatment...
US-1,009,8954 Compositions useful in alleviating pulmonary congestion and uses thereof
The invention relates to a congestion alleviating composition. The composition contains chlorophyll, tincture of pau d'arco, an herbal oil with antiviral...
US-1,009,8953 Therapeutic agent for fibroid lung
Disclosed are: a substance transfer carrier to an extracellular matrix-producing cell in the lung, which comprises a retinoid; a therapeutic agent for fibroid...
US-1,009,8952 Inorganic nanoparticles compositions in combination with ionizing radiations for treating cancer
The present application relates to activable inorganic nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or...
US-1,009,8951 Antibody/T-cell receptor chimeric constructs and uses thereof
The present application provides antibody-TCR chimeric constructs comprising an antibody moiety that specifically binds to a target antigen fused to a TCRM...
US-1,009,8950 PD-1 Peptide Inhibitors
This disclosure provides peptides which have a strong affinity for the checkpoint receptor "programmed death 1" (PD-1). These peptides block the interaction of...
US-1,009,8949 Adsorption of immunopotentiators to insoluble metal salts
Immunopotentiators can be adsorbed to insoluble metal salts, such as aluminum salts, to modify their pharmacokinetics, pharmacodynamics, intramuscular retention...
US-1,009,8948 Polysaccharide suitable to modulate immune response
Objective of the present invention is to provide polysaccharides which modulate immune response, and which can be used as ingredients in edible products or...
US-1,009,8947 Salmonella conjugate vaccines
The invention relates to a conjugate based on Vi polysaccharide which is fragmented and a carrier protein, to compositions comprising said conjugate and to...
US-1,009,8946 Computationally optimized broadly reactive antigens for influenza
The development of a computationally optimized influenza HA protein that elicits broadly reactive immune response to all H5N1 influenza virus isolates is...
US-1,009,8945 Genetically engineered swine influenza virus and uses thereof
The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN)...
US-1,009,8944 Recombinant swine influenza virus and uses thereof
Recombinant, chimeric porcine influenza viruses are disclosed that include hemagglutinin segments from more than one influenza virus subtype. Also described are...
US-1,009,8943 Flavivirus virus like particle
Provided is a virus like particle comprising one or more flavivirus structural proteins, and a composition or vaccine comprising thereof, its use in the...
US-1,009,8942 Targets of Acinetobacter baumannii
The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising...
US-1,009,8941 Immunological compositions containing attenuated Histophilus somni
This disclosure provides attenuated Histophilus somni strains, compositions comprising same, and methods of production and use thereof. The attenuated strains...
US-1,009,8940 Exotoxin/thermolysin compositions and methods and uses for treating or preventing laminitis
The disclosure relates to immunogenic and vaccine compositions comprising Streptococcus exotoxins and/or bacterial thermolysins from M4 protease family. Also...
US-1,009,8939 Reagents and methods for identifying, enriching, and/or expanding antigen-specific T cells
Antigen-specific T cells, including nave T cells, and including rare precursor cells are enriched and expanded in culture. Enrichment and expansion provides a...
US-1,009,8938 Peptides and combination of peptides for use in immunotherapy against various cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,009,8937 Peptides and combination of peptides for use in immunotherapy against various cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,009,8936 Vaccination using plant virus particles linked to HER2 antigens
A vaccine composition including a plant virus particle linked to an HER2 antigen is described. The vaccine composition can be used for methods of treating or...
US-1,009,8935 Aquaporin tolerizing vaccines and methods of use thereof
The instant disclosure provides aquaporin DNA tolerizing vaccines and methods of using such vaccines for treating individuals having neuromyelitis optica (NMO)...
US-1,009,8934 Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention...
US-1,009,8933 Compositions of engineered human arginases and methods for treating cancer
Compositions and methods for the treatment of cancer are described, and, more preferably, to the treatment of cancers that do not express, or are otherwise...
US-1,009,8932 Botulinum toxin for use in the treatment of paratonia
The present invention relates to botulinum toxins for use in the treatment of paratonia. In particular, the present invention relates to the treatment of...
US-1,009,8931 Pharmaceutical compositions and methods for fabrication of solid masses comprising immunoglobulins
Embodiments of the invention provide shaped masses comprising one or more drugs such as proteins or polypeptides and methods for forming such shaped masses. One...
US-1,009,8930 PEGylated Recombinant Human Growth Hormone Compounds
A chemically modified human Growth Hormone (rhGH) prepared by attaching a transient linker which comprises a polyethylene glycol. The chemically modified...
US-1,009,8929 Method of reducing scar formation in healing of dermal wounds by administering interleukin-10 and hyaluronan
A sustained release formulation of interleukin-10 for wound treatment and related methods is provided.
US-1,009,8928 Pharmaceutical compositions and methods for enhancing targeting of therapeutic compounds to the central nervous...
Pharmaceutical compositions and methods for enhancing targeting of therapeutic compounds to, inter alia, the CNS applied via intranasal administration while...
US-1,009,8927 Combination of growth factors, cytokines, antibacterial/antiviral factors, stem cell stimulating factors,...
The present invention refers to a combination of growth factors, cytokines, antibacterial/antiviral factors, stem cell stimulating factors, complement proteins...
US-1,009,8926 Cell
The present invention provides a cell which co-expresses a first chimeric antigen receptor (CAR) and second CAR at the cell surface, each CAR comprising an...
US-1,009,8925 Protein SLURP-1 for use in the treatment of ocular diseases
The present invention relates to a protein comprising SEQ ID NO:1 (mature form of SLURP-1) and to a composition comprising the same for use in inducing or...
US-1,009,8924 Anticancer extracts of Alpinia officinarum hance
The anticancer extracts of Alpinia officinarum Hance are produced by percolation extraction of dried Alpinia officinarum Hance rhizomes in 95% ethanol. The...
US-1,009,8923 Daphne laureola extracts in the treatment of dermopathies
The invention relates to an extract obtained from Daphne laureola L to be used the pharmaceutical cosmetic and cosmeceutical field for the topical treatment of...
US-1,009,8922 Increasing telomere length in a cell
A method of increasing the lengths of telomeres in animal cells is practiced by administering an aqueous extract of an Uncaria species to an animal. The animal...
US-1,009,8921 Method for treating gout and gout-induced arthritis using composition containing mixed extract of Chrysanthemum...
An anti-gout composition including the mixed extract of Chrysanthemum indicum and Cinnamomum cassia as an active ingredient shows substantially greater...
US-1,009,8920 Method for producing a complex of biologically active substances exhibiting hypoglycemic activity
The invention relates to medicine and chemical and pharmaceutical industry, in particular, to methods for producing a complex of biologically active substances...
US-1,009,8918 Vaporized medicants and methods of use
A method and formulation for delivering a sexual aid, such as epimedium or yohimbe, in a vaporized state using low temperatures to vaporize the formulation. The...
US-1,009,8917 Parovirus having a CpG-enriched genome useful for cancer therapy
A parvovirus characterized by a CpG-enriched genome, wherein the genome contains at least 2 additional CpG inserts that are not present in the wild type genome...
US-1,009,8916 Strains of the genus Lactobacillus and use thereof
This invention provides novel strains of the genus Lactobacillus which can be used to produce pharmaceutical products with probiotic properties for human or...
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