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Patent # Description
US-1,010,0329 Plants having increased tolerance to herbicides
The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said...
US-1,010,0328 Corn plant event MON87460 and compositions and methods for detection thereof
The present invention provides a transgenic corn event MON87460, and cells, seeds, and plants comprising DNA diagnostic for the corn event. The invention also...
US-1,010,0327 Nucleic acid imparting high-yielding property to plant, method for producing transgenic plant with increased...
An object of the present invention is to provide nucleic acids capable of imparting high-yielding ability to plants. Another object of the present invention is...
US-1,010,0326 Isolated polynucleotides and polypeptides and methods of using same for increasing plant utility
Provided are isolated polypeptides comprising the amino acid sequence at least 80% homologous to SEQ ID NO:68, 51-66, 69-100, 379-656, 707-715, 720-723,...
US-1,010,0325 Method for the production of high saturated, low polyunsaturated soybean oil
Methods of genetically modifying soybean plants to alter the fatty acid properties of the oil are described.
US-1,010,0324 Plants with modified starch metabolism
The specification provides methods of obtaining a genetically modified plant which has increased production potential compared to a control plant, the method...
US-1,010,0323 Nucleic acid sequences encoding transcription factors regulating alkaloid biosynthesis and their use in...
Plant metabolism and alkaloid levels can be regulated by transcription factors that regulate the nicotinic alkaloid biosynthetic pathway. In one embodiment, the...
US-1,010,0322 Plant with altered content of steroidal glycoalkaloids
The present invention relates to genetically modified plants by key genes involved in the biosynthesis of steroidal alkaloids. These plants have altered content...
US-1,010,0321 Methods for increasing cotton fiber length
The present invention relates to the field of plant molecular biology, more particularly cotton WRINKLED 1-like (WREL) genes. More specifically, the present...
US-1,010,0320 Pentose sugar fermenting cell
The invention relates to a cell which comprises a nucleotide sequence encoding a xylose isomerase, wherein the amino acid sequence of the xylose isomerase has...
US-1,010,0319 Compositions and methods for regulating cell osmolarity
The invention provides compositions and methods for regulating intracellular osmolarity in cells, e.g., in cultured cells, including in cultured cells in...
US-1,010,0318 Bio-field programmable gate array and bio-programmable logic array: reconfigurable chassis construction
Aspects of the invention relate to reconfigurable chassis that allow for rapid construction and optimization of biocircuits.
US-1,010,0317 Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses...
A method for treating and/or diagnosing pain and the source or type of pain, shock, and/or inflammatory conditions in a subject. A method of using a...
US-1,010,0316 Aptamers comprising CPG motifs
Materials and methods are provided for producing and using aptamers useful as oncology therapeutics capable of binding to PDGF, PDGF isoforms, PDGF receptor,...
US-1,010,0315 Treatment of PAR4 related diseases by inhibition of natural antisense transcript to PAR4
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of PAR4, in particular, by targeting natural...
US-1,010,0314 Tumor associated vaccines and compositions for disrupting tumor-derived immunosuppression for use in...
In one embodiment, a single modality cancer immunotherapy regimen that includes a therapeutic composition is provided. Such a therapeutic composition may...
US-1,010,0313 Use of Mcoln-1 modulators to regulate cell migration
The present invention relates to the use of modulators of Mcoln-1 for modulating cell migration, in particular the migration of dendritic cells and tumor cells,...
US-1,010,0312 Compositions and methods for inhibiting expression of TMPRSS6 gene
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the TMPRSS6 gene, and methods of using such dsRNA compositions to...
US-1,010,0311 Fibrotic treatment
The present invention relates to a method for the treatment of fibrosis, in particular cardiac fibrosis, comprising the administration of an inhibitor of...
US-1,010,0310 Modulation of prekallikrein (PKK) expression
Disclosed herein are antisense compounds and methods for decreasing PKK mRNA and protein expression. Such methods, compounds, and compositions are useful to...
US-1,010,0309 Targeting the steroidogenic pathway for treating and/or preventing allergic diseases
The present invention relates to methods and compositions for treating and/or preventing allergic diseases or conditions by inhibiting one or more components of...
US-1,010,0308 Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases
The present invention features methods for stimulating clearance of misfolded or aggregated proteins or peptides in microglia or neurons, and treating...
US-1,010,0307 Use of a reverse-transcriptase inhibitor in the prevention and treatment of degenerative diseases
The invention relates to the use of a reverse-transcriptase inhibitor in the prevention or treatment of a degenerative disease.
US-1,010,0306 Compositions and methods for controlling arthropod parasite and pest infestations
This application provides and discloses anti-parasitic, anti-pest or insecticidal nucleic acid molecules and their calmodulin target genes for the control of...
US-1,010,0305 Methods and compositions for manipulating translation of protein isoforms from alternative initiation of start...
Provided herein are antisense oligonucleotides, compositions comprising antisense oligonucleotides, and methods for the use of antisense oligonucleotides in...
US-1,010,0304 Modulation of exon recognition in pre-mRNA by interfering with the secondary RNA structure
The invention provides a method for generating an oligonucleotide with which an exon may be skipped in a pre-mRNA and thus excluded from a produced mRNA...
US-1,010,0302 Polynucleotide capture materials, and methods of using same
Methods for processing polynucleotide-containing biological samples, and materials for capturing polynucleotide molecules such as RNA and/or DNA from such...
US-1,010,0301 Synthesis of magnetic nanoparticles for nucleic acid purification
The present invention relates to monodisperse silanized ferrimagnetic iron oxide particles, a method for producing the same and a method for independent generic...
US-1,010,0300 Dose and location controlled drug/gene/particle delivery to individual cells by nanoelectroporation
A simple and low cost method of producing sealed arrays of laterally ordered nanochannels interconnected to microchannels of tunable size, over large surface...
US-1,010,0299 Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them
In one aspect, the invention is directed to polypeptides having an amylase and/or glucoamylase activity, polynucleotides encoding the polypeptides, and methods...
US-1,010,0298 Maltooligosyl trehalose synthase mutant and its application
The present invention relates to the field of genetic engineering and enzyme engineering, and more particularly relates to a maltooligosyl trehalose synthase...
US-1,010,0297 Nitrilase from arabis alpina, its encoding gene, vector, recombinant bacterial strain and uses thereof
The disclosure provides a nitrilase from Arabis alpina, which belongs to genus Arabis, family brassicaceae. The disclosure further provides the encoding gene,...
US-1,010,0296 Compositions for the treatment of gluten intolerance and uses thereof
The present invention provides compositions for use in the prophylaxis or treatment of a condition arising from gluten intolerance, the compositions including...
US-1,010,0295 Modified xylanase
Provided is a modified xylanase. The polypeptide has xylanase activity and has an amino acid sequence with deletion of at least 12 consecutive amino acid...
US-1,010,0294 Process for the separation of a mixture of a protein and its reaction product with a polyalkylene glycol
The present invention relates to a process for the separation of a mixture of a protein and its reaction product with a polyalkylene glycol, comprising the...
US-1,010,0293 Amylases, nucleic acids encoding them and methods for making and using them
In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using...
US-1,010,0292 Mutant endonuclease V enzymes and applications thereof
Provided herein are mutant endonuclease V enzymes that are capable of nicking an inosine-containing DNA sequence. Nucleic acid assays and agents that employ...
US-1,010,0291 Mutant Cas9 proteins
Methods of making deletion mutants of Cas9 proteins and making chimeric Cas9 proteins are described. The Cas9 N- and C-terminal domains may play critical roles...
US-1,010,0290 Glycosyltransferase glycosylating flavokermesic acid and/or or kermesic acid
An isolated glycosyltransferase (GT) polypeptide capable of: (I): conjugating glucose to flavokermesic acid (FK); and/or (II): conjugating glucose to kermesic...
US-1,010,0289 P450-BM3 variants with improved activity
The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a...
US-1,010,0288 Ketoreductase polypeptides for the reduction of acetophenones
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme....
US-1,010,0287 Biocatalysts for the preparation of hydroxy substituted carbamates
The present disclosure relates to engineered ketoreductase polypeptides for the preparation of hydroxyl substituted carbamate compounds, and polynucleotides,...
US-1,010,0286 Systems and methods of dissociating aggregate spheres of cells
Various implementations include systems and methods for automatically and continuously dissociating spheres of cells. In particular, one such system includes a...
US-1,010,0285 Ex vivo proliferation of epithelial cells
The technology relates in part to methods and compositions for ex vivo proliferation and expansion of epithelial cells.
US-1,010,0284 Method for inducing differentiation of pluripotent stem cells into endodermal cells
A synthetic peptide having a stem cell differentiation-inducing activity to induce differentiation of pluripotent stem cells into endodermal cells, a stem cell...
US-1,010,0283 Efficient chondrocyte induction method
Provided is a method for producing chondrocytes from pluripotent stem cells, the method comprising the steps of: (i) inducing pluripotent stem cells to...
US-1,010,0282 Differentiation of pluripotent cells
Provided herein are methods for the in vitro maintenance, expansion, culture, and/or differentiation of pluripotent cells, such as human embryonic stem cells...
US-1,010,0281 Truncated epiderimal growth factor receptor (EGFRt) for transduced T cell selection
A non-immunogenic selection epitope may be generated by removing certain amino acid sequences of the protein. For example, a gene encoding a truncated human...
US-1,010,0280 Generation of patient-specific differentiated cell types by epigenetic induction
Disclosure of a mammalian cytoplasmic donor cell line. Disclosure of a patient specific cell line. Methods to obtain a mammalian cytoplasmic donor cell line by...
US-1,010,0279 In vitro production of medial ganglionic eminence precursor cells
Methods and systems for generating MGE precursor cells in vitro as well as compositions of enriched MGE precursor cells are provided. The methods and systems...
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