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Patent # Description
US-1,010,0027 Benzofuran analogue as NS4B inhibitor
Provided is a benzofuran analog having a structure represented by formula (I) and used as an NS4B inhibitor, or a pharmaceutically acceptable salt of the...
US-1,010,0026 Process for treating homoserine-based compound
The present disclosure relates to the preparation of a useful compound, which can be used as an intermediate for preparing an important compound in the...
US-1,010,0025 Production of furans
The invention relates to obtaining furans from biomass. In particular, the invention relates to obtaining furans from polyols, such as tetrahydroxybutane. In...
US-1,010,0024 Process for the epoxidation of an olefin
In a process for the epoxidation of an olefin, where a mixture comprising olefin, hydrogen peroxide, water and methanol with a weight ratio of water to methanol...
US-1,010,0023 Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
Prodrugs of tizoxanide, an analog or salt thereof are disclosed. The prodrugs have an ester moiety comprising an amino acid moiety, and increase the...
US-1,010,0022 Sphingosine kinase inhibitors
Sphingosine kinases are enzymes that catalyze the biosynthesis of sphingosine-1-phosphate. The invention provides compounds that are effective for inhibition of...
US-1,010,0021 Crystalline(2S,4R)-5-(5'-chloro-2'-fluoro-[1,1'-biphenyl]-4-yl)-2-(ethoxym- ...
In one aspect, the invention relates to a crystalline form of the structure: ##STR00001## or a pharmaceutically acceptable salt thereof, having neprilysin...
US-1,010,0020 Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases
The present invention relates to a compound of formula (I), or a tautomer and/or a pharmaceutically acceptable salt thereof, wherein: R.sub.1 is alkyl, Cl, F or...
US-1,010,0019 N2-(2-methoxyphenyl)pyrimidine derivative, method for preparing same, and pharmaceutical composition for cancer...
The present invention relates to a N2-(2-methoxyphenyl)pyrimidine derivative, a preparation method thereof, and a pharmaceutical composition for the prevention...
US-1,010,0018 Amide derivatives as lysophosphatidic acid receptor antagonists
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, ##STR00001## wherein R.sup.1, X, m, R.sup.2, Y,...
US-1,010,0017 Processes for preparing olaparib
Provided herein are novel processes and methods for making 4-[(3-[(4-cyclopropylcarbonyl)piperazin-1-yl]carbonyl)-4-fluorophenyl]met- hyl(2H)phthalazin-1-one...
US-1,010,0016 Condensed ring derivative, and preparation method, intermediate, pharmaceutical composition and use thereof
Disclosed are a condensed ring derivative, and a preparation method, an intermediate, a pharmaceutical composition and a use thereof. The condensed ring...
US-1,010,0015 Condensed ring derivative, and preparation method, intermediate, pharmaceutical composition and use thereof
Disclosed are a condensed ring derivative, and a preparation method, an intermediate, a pharmaceutical composition and a use thereof. The condensed ring...
US-1,010,0014 Metallotriangle-based nanomolecules and methods of making the same
Metallotriangle-based nanomolecules are formed by a one-step self-assembly of specifically chosen shaped poly-ligand monomers, the poly-ligand monomers...
US-1,010,0013 Crystalline freebase forms of a biphenyl compound
The invention provides two crystalline freebase forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piper- ...
US-1,010,0012 Compounds as anti-tubercular agents
The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical...
US-1,010,0011 Pentadienoyl piperidine derivative and use thereof
The present invention relates to a novel pentadienoyl piperidine derivative, a pharmaceutical composition containing the same for prevention or treatment of...
US-1,010,0010 4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same
The present invention provides a 4-methoxy pyrrole derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical...
US-1,010,0009 Production of tert-butyl hydroperoxide solution and process to form products therefrom
A process for forming a concentrated solution, including distilling in a distillation zone comprised of 10 or more theoretical distillation stages, at a...
US-1,010,0008 Immunostimulating agent
Compounds represented by formula (I): ##STR00001## wherein each symbol is as defined herein, have an immunostimulatory effect and are useful as ...
US-1,010,0007 Process for preparing esters of lactic acid, and 2-hydroxy-3-butenoic acid or .alpha.-hydroxy methionine...
A continuous flow process for the preparation of one or more esters of lactic acid and 2-hydroxy-3-butenoic acid or .alpha.-hydroxy methionine analogs from a...
US-1,010,0006 Compound having immune disease treatment effect and use thereof
Provided is a novel compound capable of effectively preventing and treating immune diseases and a use thereof. The novel compound of the present subject matter...
US-1,010,0005 Mesalazine derivatives
Provided herein are compounds that are prodrugs for mesalazine. Generally, the compounds described herein correspond to a mesalazine molecule wherein the amino...
US-1,010,0004 Compounds for targeting drug delivery and enhancing siRNA activity
Here described are compounds consisting of the structure (targeting molecule).sub.m-linker-(targeting molecule).sub.n, wherein the targeting molecule is a...
US-1,010,0003 Salts of carnitine derivatives and methods of production
Disclosed are salts, such as nitrates, of acetyl-L-carnitine and propionyl-L-carnitine and methods of making the compounds.
US-1,010,0002 Method for separating N,N,N'-trimethylbisaminoethylether and/or N,N-dimethylbisaminoethylether from a mixture
The present invention relates to a method for separating N,N,N'-trimethylbisaminoethylether and/or N,N-dimethylbisaminoethylether, from a mixture A comprising...
US-1,010,0001 Adenylyl cyclase inhibitors for neuropathic and inflammatory pain
The invention generally relates to adenylyl cyclase inhibitor compounds and methods for treating neuropathic or inflammatory pain by using those compounds.
US-1,010,0000 Method for synthesizing 1,1-diamino-2,2-dinitroethylene (FOX-7) or a salt thereof
In a method for synthesizing 1,1-diamino-2,2-dinitroethylene (FOX-7) or an N-substituted diamino derivative thereof or a salt of 1,1-diamino-2,2-dinitroethylene...
US-1,009,9999 Method for synthesizing 1,1-diamino-2,2-dinitroethylene (FOX-7) or a salt thereof
In a method for synthesizing 1,1-diamino-2,2-dinitroethylene (FOX-7) or a salt thereof, an isourea derivative cation, which consists of a ...
US-1,009,9998 Compound, and separation method, synthesis method and use thereof
The invention relates to new compounds as well as a separation method, a synthetic method and use thereof. It is demonstrated by an assay on activity that the...
US-1,009,9997 Acrylic acid derivative-containing composition, and method for stabilizing acrylic acid derivative
An object of the present invention is to provide a method for stabilizing an acrylic acid derivative, and a composition containing an acrylic acid derivative in...
US-1,009,9996 Compositions and methods of use of phorbol esters in the treatment of neoplasms
Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of chronic and acute conditions. Such...
US-1,009,9995 Resveratrol esters
A resveratrol ester has the following structure: ##STR00001## R.sup.1, R.sup.2 and R.sup.3 are H or ##STR00002## Each R.sup.4 is independently a carbon...
US-1,009,9994 Process for the production of high voltage electrolyte solvents for Li-ion batteries
A method for producing halogenated carbonates is provided, the method having the steps of reacting a halogenated hydroxyl moiety with an alkyl formate in the...
US-1,009,9993 Metabotropic glutamate receptor positive allosteric modulators (PAMS) and uses thereof
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor positive allosteric modulators (PAMS), compositions comprising the...
US-1,009,9992 Method for separating formic acid from a reaction mixture
The invention relates to a method for separating formic acid from a reaction mixture which comprises, in addition to formic acid, a polyoxometalate ion of...
US-1,009,9991 Process for the separation of dicarboxylic acids from aqueous mixtures
This invention relates to a process for the separation of dicarboxylic acids from aqueous mixtures of CV.sub.8C.sub.24 mono- and dicarboxylic acids. In...
US-1,009,9990 Process for flashing a reaction medium
A process for producing acetic acid is disclosed in which the methyl iodide concentration is maintained in the vapor product stream formed in a flashing step....
US-1,009,9989 Distillation process for production of acrylic acid
Provided are integrated processes for the conversion of beta propiolactone to acrylic acid. Systems for the production of acrylic acid are also provided.
US-1,009,9988 Process for production of acrylic acid
Provided are integrated processes for the conversion of beta propiolactone to acrylic acid. Systems for the production of acrylic acid are also provided.
US-1,009,9987 Process for preparing synthesis intermediates using products of natural origin and use of the intermediates...
Disclosed is a process for preparing a product of formula I: wherein the reaction is catalyzed both by thiamine or a thiamine salt and by ascorbic acid in a...
US-1,009,9986 Hydrosilane/Lewis acid adduct, particularly aluminum, iron, and zinc, method for preparing same, and use of...
Disclosed is an adduct between a Lewis acid, preferably aluminum trichloride, iron trichloride, or zinc dichloride, and a hydrosilane;--a method for preparing...
US-1,009,9985 Method for producing ketone and/or alcohol, and system thereof
This invention provides producing having an objective ketone and/or alcohol by decomposing of a hydrocarbon compound rapidly and selectively having a same...
US-1,009,9984 Narrow range alcohol alkoxylates and derivatives thereof
The present invention relates generally to narrow range alcohol alkoxylates and derivatives thereof, such as alkyl ether sulfates.
US-1,009,9983 Narrow range alcohol alkoxylates and derivatives thereof
The present invention relates generally to narrow range alcohol alkoxylates and derivatives thereof, such as alkyl ether sulfates.
US-1,009,9982 Methods of making halogenated partially fluorinated compounds
Described herein is method of making a halogenated partially fluorinated compound, comprising: (a) providing a compound having the following structure of...
US-1,009,9981 Methods for meta-arylation of aromatic alcohols
Provided are methods for the meta-selective C--H arylations of arene alcohol-based substrates. The methods combine the transient norbornene strategy with a...
US-1,009,9980 Glycol recovery with solvent extraction
A method of recovering an alcohol from an aqueous stream comprising: providing an aqueous stream comprising water and an alcohol; providing a solvent stream;...
US-1,009,9979 Catalytic methods for the production of an alcohol from an alkane
The present invention generally relates to apparatuses, systems, and methods for oxidation of an alkane (e.g., methane) into an alcohol (e.g., methanol) in the...
US-1,009,9978 Catalyst and method for hydrogenation of 1,3-cyclobutanediketone compound
Catalyst for hydrogenation of 1,3-cyclobutanediketone compound is provided, which includes a support and VIIIB group transition metal loaded thereon. The...
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