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Patent # Description
US-1,013,7153 Methods for treating an infectious or neoplastic disease
A method is provided for treating a subject suffering from an infectious or neoplastic disease with immunotherapy. The method comprises determining the critical...
US-1,013,7152 Inoculation by applying nanosecond pulsed electric fields to a biopsy and reintroducing the treated biopsy to...
A subject is inoculated from a disease by exposing a biopsy of a tumor or other abnormal growth to a nanosecond pulsed electric field (nsPEF). A sufficient...
US-1,013,7151 Therapeutic detoxification compositions and methods of making and using same
A three component composition for use in the treatment of an autoimmune disease where the first component comprises a bimodal synthetic carbon particle mixture;...
US-1,013,7150 Graphene and graphene-related materials for manipulation of cell membrane potential
Structures based on graphene-related materials, methods for their preparation, and methods for their use are disclosed. These structures can be utilized for...
US-1,013,7149 Particles for the treatment of cancer in combination with radiotherapy
The invention provides a particle comprising a metal oxide which is doped with at least one rare earth element, wherein the metal oxide is selected from...
US-1,013,7148 Reducing the proliferation of adenocarcinoma cells (CaCo-2) by administration of a poly-oxygenated metal hydroxide
A method of treating a mammal, comprising administering a therapeutically effective amount of a poly-oxygenated metal hydroxide composition to a mammal to...
US-1,013,7147 Reducing the proliferation of lung carcinoma cells (A549) by administration of a poly-oxygenated metal hydroxide
A method of treating a mammal, comprising administering a therapeutically effective amount of a poly-oxygenated metal hydroxide composition to a mammal to...
US-1,013,7146 Oxygen-enabled composition
A composition of chlorine-free poly-oxygenated metal hydroxide that comprises a clathrate containing oxygen gas molecules, and which may comprise a...
US-1,013,7145 Meningococcal vaccine based on lipooligosaccharide (LOS) originating from modified Neisseria meningitidis...
The invention especially relates to multivalent vaccine compositions that can treat or prevent at least 60, preferably 75% of infections caused by Neisseria...
US-1,013,7144 Methods and compositions for the activation of gamma-delta T-cells
The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can...
US-1,013,7143 Preventing tumor development and metastasis
Treatment of tumors, especially breast cancer or glioblastoma tumors, by silencing RAB27A and/or TRAF3IP2, compositions and methods for same.
US-1,013,7142 Topical pharmaceutical formulations containing a low concentration of benzoyl peroxide in suspension in water...
An aqueous formulation for topical application to the skin comprising water, a water-miscible organic solvent, and benzoyl peroxide, wherein the concentration...
US-1,013,7141 Treatment regimen tiacumicin compound
A tiacumicin compound, a stereo-isomer thereof, a polymorph thereof or a pharmaceutically acceptable solvate thereof, and a pharmaceutical composition,...
US-1,013,7140 Therapeutic composition
This invention relates to a topical composition for prevention and treatment of viral infections.
US-1,013,7139 Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
Osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions.
US-1,013,7138 Sulfonylurea derivatives of oleanolic acid
The sulfonylurea derivatives of oleanolic acid include compounds replacing the 5-chloro-2-methoxybenzoic acid moiety found in glibenclamide with oleanolic acid....
US-1,013,7137 ATP synthase inhibitors and steroid alkaloids and uses thereof as antimicrobial agents and as potentiators for...
The present invention provides bacterial ATP synthase inhibitors such as a compound of formula (I): (Formula (I)) (A) in combination with an aminoglycoside...
US-1,013,7136 Methods for inhibiting muscle atrophy
In one aspect, the invention relates to methods for treating muscle atrophy by providing to an animal in need thereof an effective amount of a compound. The...
US-1,013,7135 Formulations and methods for providing progestin-only contraception while minimizing adverse side effects...
Formulations and methods for providing progestin-only contraception to a woman while minimizing various side effects, such as breakthrough bleeding, that are...
US-1,013,7134 Molybdenum compounds for use in the treatment of cyanide poisoning
The present invention relates to compositions comprising molybdenum compounds, novel molybdenum compounds, kits and methods for their preparation. In...
US-1,013,7133 Methods for treatment of diseases
The present disclosure relates to methods of treating a range of diseases or conditions. The methods involve administration of a superoxide dismutase mimetic.
US-1,013,7132 Parenteral formulations of dopamine agonists
This invention relates to stable pharmaceutical compositions for parenteral administration comprising dopamine agonists and peripheral acting agents useful for...
US-1,013,7131 Pharmaceutical compositions comprising meloxicam
Disclosed herein are compositions comprising a drug such as a triptan (e.g. rizatriptan) and/or an NSAID (e.g. meloxicam) in combination with a cyclodextrin...
US-1,013,7130 Methods of treatment of malignancies
Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
US-1,013,7129 Prophylactic agent and/or therapeutic agent for diffuse large B-cell lymphoma
To provide a medicament which shows more remarkable effect in treatment of activated B-cell like diffuse large B-cell lymphoma (ABC-CLBCL) than the existing Btk...
US-1,013,7128 Methods of improving myocardial performance in fontan patients using udenafil compositions
The present invention relates generally to the field of using udenafil or a pharmaceutically acceptable salt thereof in patients who have undergone the Fontan...
US-1,013,7127 Liquid formulations of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyri- ...
A liquid formulation of (S)--N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyri- midin-3-yl)-3-hydroxypyrrolidine-1-carboxamide,...
US-1,013,7126 Method of preparing very slightly soluble drug with solid dosage form
A method of preparing a very slightly soluble drug with solid composition includes the following steps: (a) adding a very slightly soluble drug into an organic...
US-1,013,7125 Benzenesulfonamide derivatives of quinoxaline, pharmaceutical compositions thereof, and their use in methods...
Benzenesulfonamide derivatives of quinoxaline that are kinase inhibitors, pharmaceutical compositions and methods of using these derivatives, e.g., for...
US-1,013,7124 Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors
Provided herein are compounds of the Formula I: ##STR00001## and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B,...
US-1,013,7123 Methods and compositions for prevention and treatment of cardiac hypertrophy
Methods are provided of treating cardiac hypertrophy in a mammalian subject comprising administering to the subject an anti-hypertrophic effective amount of an...
US-1,013,7122 Kinase inhibitors and methods of use thereof
The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the...
US-1,013,7121 Methods of treating cancer with farnesyltransferase inhibitors
The present invention relates to the field of cancer therapy. Specifically, provided are methods of treating cancer, for example, peripheral T-cell lymphoma...
US-1,013,7120 Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides
Compounds are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating...
US-1,013,7119 Anti-malarial agent
The invention aims to prevent and/or treat malaria using an antimalarial drug comprising, as an active ingredient, a metal chelator represented by the following...
US-1,013,7118 Crystalline polymorphs of the free base of ...
Disclosed are crystalline free base ansolvate forms of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzald- ehyde (or Compound 1), such as...
US-1,013,7117 Crystalline N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2[4-(2-pyridinyl- )phenyl]acetamide...
The present invention relates to the crystalline mono mesylate monohydrate salt of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridiny- ...
US-1,013,7116 Benzimidazole sulfide derivatives for the treatment or prevention of tuberculosis
The present invention relates to the use of benzimidazole sulfide derivatives and prodrugs thereof in the treatment and/or prevention of tuberculosis.
US-1,013,7115 Therapeutic inhibitor for EBV-associated tumor with tailor responsive optical imaging
This invention provides a nucleus-permeable small-molecule inhibitor, L.sub.2P.sub.4 (where L.sub.2 is 4-(4-(Diethylamino)styryl)-N-carboxymethylpyridinium...
US-1,013,7114 Rifaximin ready-to-use suspension
A stable, taste-masked, ready-to-use suspension comprising rifaximin dispersed in a suspension base and one or more pharmaceutically acceptable additive(s)....
US-1,013,7113 5-HT4 receptor agonist as a prokinetic agent
This invention relates to Compound A or a pharmaceutically acceptable salt thereof with 5-HT4 agonistic activities, which is useful in the treatment of...
US-1,013,7112 Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second...
Disclosed herein are pharmaceutical compositions, methods and kits for lowering the serum uric acid level of a subject and for the treatment of a condition...
US-1,013,7111 Drug compositions comprising an anti-parasitic and proton pump inhibitor
Described herein are pharmaceutical compositions including a proton pump inhibitor and an antiparasitic drug. In some embodiments, the compositions can be...
US-1,013,7110 1-cyclohexyl-2-phenylaminobenzimidazoles as mIDH1 inhibitors for the treatment of tumors
The present invention relates to benzimidazol-2-amines of general formula (I) in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8,...
US-1,013,7109 Carbazole compounds and therapeutic uses of the compounds
Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable...
US-1,013,7108 Nutritional composition useful in the treatment of IBD patients
Compositions and methods are provided that are useful in the treatment of inflammatory bowel disease (IBD) patients. The Compositions and methods are suitable...
US-1,013,7107 Substituted phenylpyrrolecarboxamides with therapeutic activity in HIV
Substituted phenylpyrrolecarboxamide compounds such as those represented by Formula A can be used in the treatment of HIV infection and related conditions.
US-1,013,7106 Compositions and methods to treat niemann-pick disease
The present disclosure is directed to compositions comprising bryostatin-1, and methods comprising administering a composition comprising bryostatin-1, to treat...
US-1,013,7105 Combination treatment protocol
The present disclosure provides a combination and a method for treating chronic lymphocytic leukemia (CLL).
US-1,013,7104 Combination therapy with an anti-hyaluronan agent and therapeutic agent
Provided herein is combination cancer therapy effected by administering a polymer-conjugated hyaluronidase, and a tumor-targeted taxane, and optionally a...
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