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| Patent # | Description |
|---|---|
| US-1,015,0790 |
Depolymerisation of lignin in biomass A method of obtaining depolymerized lignin from biomass using a transition metal catalyst and a solvent mixture of organic solvent and water. The invention... |
| US-1,015,0789 |
Molybdenum imide compound In the method of the present invention for producing a thin film, including introducing, onto a substrate, a vapor that has been obtained by vaporizing a... |
| US-1,015,0788 |
Prodrug compounds and uses thereof Provided herein are cyclic phosphorus-containing prodrug compounds, their preparation and their uses, such as treating diseases via modulating molecular targets... |
| US-1,015,0786 |
Silicone surfactants for emulsion assays System, including methods and compositions, for making and using emulsions that include a silicone oil and a silicone surfactant. The emulsions may include... |
| US-1,015,0785 |
Method for producing dialkylaminosilane In a method for synthesizing dialkylaminosilane from a reaction of dialkylamine with chlorosilane as the method for producing dialkylaminosilane, a large amount... |
| US-1,015,0784 |
Crystal polymorph of magnesium glycinate dihydrate and process for its
preparation Embodiments of the invention provide solid forms of magnesium glycinate dihydrate and compositions thereof, which are useful for treating hyperphosphatemia and... |
| US-1,015,0783 |
Heterocyclic ITK inhibitors for treating inflammation and cancer Disclosed herein are heterocyclic compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structure of... |
| US-1,015,0782 |
Heterocycle-substituted bicyclic azole pesticides Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, ##STR00001## wherein Q is ##STR00002## and... |
| US-1,015,0781 |
2-oxothiatole compounds having activity as CPLA2 inhibitors for the
treatment of inflammatory disorders and... A compound of formula (I') ##STR00001## wherein R.sub.6 is H, C.sub.1-6alkyl, --(CH.sub.2).sub.pCOOH, --(CH.sub.2).sub.pCOOC.sub.1-6alkyl,... |
| US-1,015,0780 |
Spirocyclic heterocycle compounds useful as HIV integrase inhibitors The present invention relates to Spirocyclic Heterocycle Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, B, X, R.sup.1,... |
| US-1,015,0779 |
Aldose reductase inhibitors and methods of use thereof The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of... |
| US-1,015,0778 |
Production method of thienopyrimidine derivative The present invention provides a production method of a thienopyrimidine derivative or a salt thereof which has a gonadotropin releasing hormone (GnRH)... |
| US-1,015,0777 |
Production of pyripyropenes from dry biomass The invention pertains to processes to produce dry biomass of pyripyropene producer organisms, processes to obtain pyripyropenes from such dry biomass, as well... |
| US-1,015,0776 |
Harringtonines salts in the crystalline state and their use for the
purification of the corresponding drug... The present disclosure concerns harringtonines salts at the crystalline state exhibiting a protonated nitrogen seen in solid state analysis and having general... |
| US-1,015,0775 |
6-amido derivatives of 4,5A-epoxymorphinans for treatment of pain Compounds of formula: ##STR00001## in which R.sup.4 is chosen from substituted phenyl, optionally substituted naphthylene, optionally substituted anthracene... |
| US-1,015,0774 |
Compounds and methods The subject matter generally relates to compounds and methods of treatment and/or prophylaxis of CNS diseases, disorders, and/or injuries. In one aspect, the... |
| US-1,015,0773 |
N-substituted 8-[(2,6-difluorobenzyl)oxy]-2,6-
dimethylimidazo[1,2-a]pyrazin-3-carboxamide derivatives as... The present application relates to novel substituted imidazo[1,2-a]pyrazine carboxamides of general formula (I) ##STR00001## to processes for their... |
| US-1,015,0772 |
Crystalline forms of PARP inhibitors The present disclosure relates to crystalline forms of 4,5,6,7-tetrahydro-11-methoxy-2-[(4-methyl-1-piperazinyl)methyl]-1H-cyclo- ... |
| US-1,015,0771 |
Triazolopyrazinones as PDE1 inhibitors The present invention provides triazolopyrazinones as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative... |
| US-1,015,0770 |
Crystal form of bisulfate of JAK inhibitor and preparation method therefor A crystal form I of a Janus Kinase (JAK) inhibitor (3aR,5s,6aS)--N-(3-methoxyl-1,2,4-thiadiazole-5-yl)-5-(methyl(7H-pyrrolo[- ... |
| US-1,015,0769 |
Spiro-lactam NMDA modulators and methods of using same Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression... |
| US-1,015,0768 |
Guanidine substituted imidazo[4,5-c] ring compounds Imidazo[4,5-c] ring compounds, (particularly imidazo[4,5-c]quinolines, 6,7,8,9-tetrahydroimidazo[4,5-c]quinolines, imidazo[4,5-c]naphthyridines, and... |
| US-1,015,0767 |
Therapeutic compounds and uses thereof The present invention relates to compounds of formula (I): ##STR00001## and to salts thereof, wherein R.sup.1, R.sup.2, and Q have any of the values defined in... |
| US-1,015,0766 |
P2X7 modulators The present invention is directed to compounds of Formula (I), which includes enantiomer and diasteromers thereof: ##STR00001## The invention also relates to... |
| US-1,015,0765 |
P2X7 modulators The present invention is directed to compounds of Formulas (I, IIa and IIb): ##STR00001## The invention also relates to pharmaceutical compositions comprising... |
| US-1,015,0764 |
Substituted benzene compounds The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and... |
| US-1,015,0763 |
Histone deacetylase inhibitors and their use in therapy A compound of the formula:(I) or a pharmaceutically acceptable salt thereof, wherein: L is a 5-membered nitrogen-containing heteroaryl which is optionally fused... |
| US-1,015,0762 |
Trifluoromethyl alcohols as modulators of ROR.gamma.t The present invention comprises methods of making 5-(2,3-dichloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-- ... |
| US-1,015,0761 |
Substituted pyridine-piperazinyl analogues as RSV antiviral compounds The invention concerns novel substituted pyridine-piperazinyl analogs of formula (I) having antiviral activity, in particular, having an inhibitory activity on... |
| US-1,015,0760 |
Compounds for use in preparing heterocyclic triazole agonists of the APJ
receptor Compounds of Formula V, salts thereof, tautomers thereof, and salts of the tautomers have the following structure and are useful compounds in preparing small... |
| US-1,015,0759 |
1,4-pyridone bicycic heteroaryl compounds The present invention relates to 1,4-pyridone bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these... |
| US-1,015,0758 |
PRMT5 inhibitors and uses thereof Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present... |
| US-1,015,0757 |
Quinazolinone derivatives as PARP inhibitors The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of... |
| US-1,015,0756 |
Diaminopyrimidine benzenesulfone derivatives and uses thereof The present invention provides compounds of Formula (II) (e.g., compounds of Formula (I)), and pharmaceutically compositions thereof. Compounds of Formula (II)... |
| US-1,015,0755 |
ASK1 inhibitor compounds and uses thereof Described herein are compounds, including pharmaceutically acceptable salts, solvates, metabolites, prodrugs thereof, methods of making such compounds,... |
| US-1,015,0754 |
Histone demethylase inhibitors The present embodiments provide for substituted triazolylpyridine derivative compounds, and pharmaceutical compositions comprising said compounds. The subject... |
| US-1,015,0753 |
Salt forms and polymorphs of
(R)-1-(4-(6-(2-(4-(3,3-difluorocyclobutoxy)-6-methylpyrdin-2-yl)acetamido-
)... Disclosed herein is the compound (R)-1-(4-(6-(2-(4-(3,3-difluorocyclobutoxy)-6-methylpyridin-2-yl)acetamid- ... |
| US-1,015,0752 |
Substituted triazole derivatives as oxytocin antagonists The present invention relates to substituted triazoles of formula (I), uses thereof, processes for the preparation thereof and compositions containing said... |
| US-1,015,0751 |
Pyrrolidine orexin receptor antagonists The present invention is directed to pyrrolidine compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the... |
| US-1,015,0750 |
Process for the oxidation of organic carbonyl compounds A process for the oxidation of an organic carbonyl compound comprising reacting the compound, optionally in the presence of a solvent, with hydrogen peroxide in... |
| US-1,015,0749 |
Method for obtaining vitamin E, sterols and/or terpenes from oily or fatty
mixtures of biological origin Disclosed is a continuous process for concentrating or separating of vitamin E, sterols and/or terpenes from oily or fatty mixtures of biological origin... |
| US-1,015,0748 |
Salt or abexinostat, associated crystalline form, a process for their
preparation and pharmaceutical... Abexinostat tosylate of formula (II): ##STR00001## and its crystalline form I characterized by its X-ray powder diffraction diagram, its Raman spectrum and... |
| US-1,015,0747 |
Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity... |
| US-1,015,0746 |
Preparation of pantolactone The present invention relates to a novel process for the preparation of pantolactone by reaction of hydroxypivalaldehyde cyanohydrin in a phase separation process. |
| US-1,015,0745 |
Process for the preparation of clobazam and its intermediate The present invention provides an improved process for the preparation of 8-chloro-1-phenyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dione (hereafter referred to as... |
| US-1,015,0744 |
P2X4 receptor antagonist The present invention relates to a compound represented by the following general formula (I), which has a P2X4 receptor antagonistic activity (in the formula,... |
| US-1,015,0743 |
Carboxylic acid compounds The present disclosure concerns at least one entity chosen from compounds of Formula (I) and pharmaceutically acceptable salts thereof: ##STR00001## wherein... |
| US-1,015,0742 |
Substituted heterocyclic compounds for treating or preventing viral
infections Disclosed herein are pyrimidine compounds of formula I and formula II and methods for treating or preventing a viral infection, such as infections caused by... |
| US-1,015,0741 |
Method for preparing azoxystrobin intermediates The present invention provides a method for preparing azoxystrobin intermediates, comprising reacting compound A and dichloropyrimidine in the presence of a... |
| US-1,015,0740 |
6,7-dihydropyrido[2,1-A]phthalazin-2-ones for the treatment and
prophylaxis of hepatitis B virus infection The invention provides novel compounds having the general formula: ##STR00001## wherein R.sup.1 to R.sup.6 are as described herein, compositions including the... |
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