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Patent # Description
US-1,016,6262 Strain of bacteria and composition comprising the same
The invention is directed to a novel strain of Lactobacillus plantarum AMT14 and compositions comprising the same.
US-1,016,6261 Bacillus coagulans MTCC 5856 for the management of major depressive disorder
The present invention discloses the use of probiotics for therapeutic management of major depressive disorder (MDD). Specifically, the invention discloses the...
US-1,016,6260 Wound care product with egg shell membrane
A wound care product in the form of a gel is provided, and contains protein from egg shell membrane. The gel is made by first hydrating the egg shell membrane...
US-1,016,6259 Isolation of exosomes from colostrum powder and exosomal drug formulations using the same
A method for isolation of exosomes from bovine colostrum powder or goat colostrum powder, and the use of the isolated exosomes as nano carriers for small drug...
US-1,016,6258 Compositions containing platelet contents
This document provides methods and materials relating to platelet lysates. For example, methods and materials for using platelet lysate compositions to grow...
US-1,016,6257 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for...
US-1,016,6256 Anti-tumor T cell immunity induced by high dose radiation
Cancer treatment is provided, by irradiating an individual with a localized, high single dose or short course of doses at a primary tumor site; collecting T...
US-1,016,6255 Intracellular genomic transplant and methods of therapy
Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using...
US-1,016,6254 Use of mesenchymal stem cell-educated macrophages to treat and prevent graft versus host disease and...
The present invention relates to methods for treating and preventing graft-versus-host disease (GVHD) and radiation-induced tissue damage or organ failure. More...
US-1,016,6253 Positively charged co-polymers for use as antimicrobial agents
The present invention provides a positively charged co-polymer for use as an antimicrobial agent, wherein said positively charged co-polymer is composed of...
US-1,016,6252 Method for assessing and treating or preventing impaired plasma polar lipid levels
The invention pertains to the use of a preparation for the manufacture of a composition for preventing or treating impaired plasma levels of one or more polar...
US-1,016,6251 STAT5a and its functional tumor suppressor analogs for treatment of malignancies expressing NPM/ALK and other...
The invention provides methods of inhibiting epigenetic gene silencing in a cell expressing NPM/ALK or decreasing NPM/ALK content in a cell, by contacting a...
US-1,016,6250 Bicyclic aryl sphingosine 1-phosphate analogs
Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphin-gosine analogs that, after phosphorylation, can...
US-1,016,6249 Substituted bicyclic compounds
Disclosed are compounds of Formulas (I), (II), (III), (IV), and (V): ##STR00001## and/or a salt thereof, wherein R.sub.1 is --OH or --OP(O)(OH).sub.2, and...
US-1,016,6248 Methods of preventing platelet activation
A method of preventing or reducing the occurrence of malondiadehyde and/or levuglandin protein modification in a subject in need thereof, comprising...
US-1,016,6247 Composition for inhalation
The invention relates to a formulation comprising formoterol and budesonide for use in the treatment of respiratory diseases. The composition further contains...
US-1,016,6246 TGR5 agonist complexes for treating diabetes and cancer
Provided herein are complexes of metformin or metformin analogues and a TGR5 ligand that are useful in treating diseases including diabetes, cardiovascular...
US-1,016,6245 Enzymatic process for obtaining 17 alpha-monoesters of cortexolone and/or its 9,11-dehydroderivatives
The present invention refers to a new enzymatic process for obtaining 17.alpha.-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the...
US-1,016,6244 Targeting NC.sub.CA-ATP channel for organ protection following ischemic episode
The present invention concerns protection of an organ or tissue outside of the central nervous system following an ischemic episode. In particular aspects, the...
US-1,016,6243 Optimizing mifepristone levels for cushing'S patients
The present invention provides a method for optimizing levels of mifepristone in a patient suffering from Cushing's syndrome. The method comprises the steps of...
US-1,016,6242 Optimizing mifepristone levels for Cushing's patients
The present invention provides a method for optimizing levels of mifepristone in a patient suffering from Cushing's syndrome. The method comprises the steps of...
US-1,016,6241 Combination Therapy III
The invention is based on a finding that silencing HDAC4gene sensitizes cancer cells for apoptosis-inducing activity of certain small molecule chemotherapeutic...
US-1,016,6240 Pharmaceutical compositions and methods for anesthesiological applications
Pharmaceutical compositions and methods for inducing conscious sedation using such compositions are described, the compositions including a benzodiazepine-based...
US-1,016,6239 Tropomyosin-related kinase (Trk) inhibitors
Tropomyosin-related kinase inhibitors (Trk inhibitors) are small molecule compounds useful in the treatment of disease. Trk inhibitors can be used as...
US-1,016,6238 EZH2 inhibitors for treating lymphoma
The present invention relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and their use for the treatment of cancer.
US-1,016,6237 Compounds and methods for inducing chondrogenesis
The present invention provides compounds and compositions for the amelioration of arthritis and joint injuries by inducing mesenchymal stem cells into...
US-1,016,6236 Pharmaceutical formulations comprising substituted pyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazines for treating...
This disclosure provides compounds, such as compounds of Formula I: ##STR00001## pharmaceutical formulations thereof, and related methods of use for the...
US-1,016,6235 Kinetin/zeatin topical formulation
The solubility of kinetin and/or of zeatin is increased when either or both are combined in a formulation that includes a polyoxyalkylene-n-glycerol...
US-1,016,6234 Pharmaceutical preparation comprising phenylalanine derivative
The disclosed pharmaceutical preparation comprises a compound represented by the chemical formula (A) or a pharmaceutically acceptable salt thereof, which is...
US-1,016,6233 Outpatient modified rapid detoxification for addiction to alcohol and drugs
A program for outpatient modified rapid detoxification for addiction to alcohol and drugs is disclosed. Patients are seen by trained medical professionals who...
US-1,016,6232 Arylamide compounds and compositions and uses thereof
The present invention discloses ophthalmic and otic compositions of facially amphiphilic antimicrobial polymers and oligomers and their uses, including their...
US-1,016,6231 Freeze dried drug nanosuspensions
The present invention relates to a freeze-dried (also called lyophilized) drug nanosuspension. The present freeze-dried drug nanosuspension composition has an...
US-1,016,6230 Treatment of vasomotor symptoms
The invention relates to a method for the treatment of vasomotor symptoms comprising the administration of a therapeutically effective amount of flibanserin.
US-1,016,6229 Compounds and methods for the treatment of cancer
Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis...
US-1,016,6228 Polymorphic forms of naltrexone
This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and...
US-1,016,6227 Bromodomain and extra-terminal protein inhibitor combination therapy
The present disclosure relates generally to compositions and methods of treating neoplastic diseases or cancers, such as glioblastoma and non-Hodgkin's...
US-1,016,6226 CGRP receptor antagonists
The disclosures herein relate to novel compounds of formula ##STR00001## wherein Ar.sup.1 and R.sub.1 are as defined herein, and their use in treating,...
US-1,016,6225 Method for treating osteoporosis
This invention is directed to the treatment of osteoporosis using N-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyc- ...
US-1,016,6224 Nicotine salt with meta-salicylic acid and applications therein
The present disclosure relates generally to the field of nicotine delivery. The disclosure teaches a nicotine meta-salicylate. More specifically, the disclosure...
US-1,016,6223 Pharmaceutical composition for prevention or treatment of diabetes or fatty liver comprising CYP4A inhibitor
The present invention relates to a pharmaceutical composition for the prevention or treatment of diabetes or fatty liver comprising a CYP4A (cytochrome P450A)...
US-1,016,6222 Piperidine-2, 6-dione derivatives and their use as tumor necrosis factor inhibitors
This invention is directed to derivatives of piperidine-2,6-dione, or their organic or inorganic salts thereof, a methods of synthesis of these derivatives, and...
US-1,016,6221 Formulations of an LSD1 inhibitor
The present application relates to pharmaceutical formulations and dosage forms of a lysine specific demethylase-1 (LSD1) inhibitor, or a pharmaceutically...
US-1,016,6220 Fexofenadine microcapsules and compositions containing them
The present invention provides a pharmaceutical composition comprising taste-masked immediate release microcapsules which comprise fexofenadine and a...
US-1,016,6219 Formulations and methods of manufacturing formulations for use in colonic evacuation
Formulations and methods of manufacturing formulations for use in colonic evacuation are disclosed herein, in an embodiment, a solid dosage formulation includes...
US-1,016,6218 3-(1H-indol-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
6-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a...
US-1,016,6217 Fungal keratitis prophylactic or therapeutic agent
For preventing or treating keratomycosis, a medicament containing rapamycin or a salt thereof as an active ingredient is used.
US-1,016,6216 Substituted triazoles useful as Axl inhibitors
Substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein...
US-1,016,6215 Substituted bicyclic compounds as bromodomain inhibitors
The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical...
US-1,016,6214 Somatostatin receptor subtype 4 (SSTR4) agonists
3-aza-bicyclo[3.1.0]hexane-6-carboxylic acid amide derivatives which are agonists of somatostatin receptor subtype 4 (SSTR4), useful for preventing or treating...
US-1,016,6213 Derivatives of korormicin useful as antibiotics
An antibiotic compound is of formula (I): ##STR00001## R.sup.1-R.sup.3, R.sup.5 and R.sup.6 are independently selected from H, alkyl group, substituted alkyl...
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