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Patent # Description
US-1,020,2489 Lactide copolymers and ring-opened lactide copolymers
A process of forming a lactide copolymer includes forming a dimethylidene lactide molecule from an L-lactide molecule. The process also includes forming a...
US-1,020,2488 Isocyanate-free synthesis of carbonate-modified polymers
The present invention relates to an isocyanate-free and preferably solvent-free process for preparing polymers containing five-membered cyclic carbonate groups....
US-1,020,2487 Polyarylate and molded article using same
The present invention can provide a polyarylate obtained from a dihydric phenol component and an aromatic dicarboxylic acid component. The polyarylate is...
US-1,020,2486 Poly(oxyalkylene)urethanes as a solubilizer and stabilizer in active ingredient formulations
Poly(oxyalkylene)urethane surfactants of the formula (I) R.sup.2--X--OCHN--[R.sup.1--NHCO--O--[(CH.sub.2).sub.q--O].sub.x--CONH--]- ...
US-1,020,2485 Polymerizable composition for optical material, optical material, and method of manufacturing optical material
The polymerizable composition for an optical material of the present invention includes: (A) a compound having a carbon-carbon triple bond and at least one...
US-1,020,2484 Shape-memory-self-healing polymers (SMSHPS)
A shape-memory self-healing polymeric network (SMSHP) is useful as a molded part, a coating, or as a matrix for a composite that can be repaired by heating to a...
US-1,020,2483 Polymerizable composition, molded product, and use thereof
The polymerizable composition of the present invention includes at least one isocyanate compound (A) having a cyclic structure, selected from compounds...
US-1,020,2482 Viscoelastic foams having high dissipation energy
A viscoelastic polyurethane foam formed from a polyisocyanate and a polyol composition comprising palm olein-based polyol in an amount of 10% to 35% by weight...
US-1,020,2481 Block copolymer
The present application provides the block copolymers and their application. The present application may provide the block copolymers that have excellent self...
US-1,020,2480 Block copolymer
The present application provides the block copolymers and their application. The block copolymer has an excellent self assembling property and phase separation...
US-1,020,2479 Poly(cyclohexylethylene)-polyacrylate block copolymers, methods of manufacture thereof and articles comprising...
Disclosed herein is a block copolymer comprising a first block derived from a cyclo-alkyl vinyl monomer, a hydrogenated vinyl aromatic polymer or a hydrogenated...
US-1,020,2478 Multigraft copolymer superelastomers by emulsion polymerization
Multigraft copolymers having various structures, e.g., comb and centipede structures, can be prepared from emulsion copolymerization of monomers and...
US-1,020,2477 Optically clear hot melt processable high refractive index adhesives
Adhesive compositions that are optically transparent include a (meth)acrylate-based copolymer having a refractive index of at least 1.48, and particles of a...
US-1,020,2476 Polybutene preparation method
A method for preparing polybutene includes the steps of: supplying a C4 mixture to an isomerization reactor in which (i) 1-butene is isomerized into 2-butene by...
US-1,020,2475 Propylene copolymer for extrusion blow molded bottles
Extrusion blow molded article comprising a propylene copolymer having a high bottle appearance factor and good impact properties.
US-1,020,2474 Process for producing polydienes
A method for producing a polydiene, the method comprising the steps of (i) forming an active catalyst by combining a lanthanide-containing compound, an...
US-1,020,2473 Hydrophilic polymeric particles and methods for making and using same
A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having...
US-1,020,2472 Olefin polymerization process
A process for the preparation of an ethylene polymer including the step of polymerizing ethylene or copolymerizing ethylene and one or more other olefins in the...
US-1,020,2470 Polymerizable composition and optically anisotropic body using same
The present invention provides a polymerizable composition containing a specific polymerizable compound and a fluorosurfactant having a specific polyoxyalkylene...
US-1,020,2469 Sugar chain-attached linker, compound containing sugar chain-attached linker and physiologically active...
To provide a carrier linker that is capable of improving the water solubility of a physiologically active substance and more quickly releasing the...
US-1,020,2468 Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
A particulate SAE-CD composition is provided. The SAE-CD composition has an advantageous combination of physical properties not found in known solid forms of...
US-1,020,2467 Methods and compositions for increasing .alpha.-L-iduronidase activity in the CNS
Provided herein are methods and compositions for treating a subject suffering from a deficiency in .alpha.-L-Iduronidase in the CNS. The methods include...
US-1,020,2466 Linked peptide fluorogenic biosensors
Biosensors, compositions comprising biosensors, methods of producing biosensors, and methods of using biosensors are disclosed. The biosensors comprise a...
US-1,020,2465 Methods for treating conditions associated with MASP-2 dependent complement activation
In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the...
US-1,020,2464 Immunoconjugates
The present invention generally relates to antigen-specific immunoconjugates for selectively delivering effector moieties that influence cellular activity. More...
US-1,020,2463 Cell-based anti-cancer compositions with reduced toxicity and methods of making and using the same
Isolated pluralities of T cells which recognize at least one epitope of an intestinal cancer antigen or CNS cancer antigen and pharmaceutical compositions...
US-1,020,2462 Bi-specific antigen-binding polypeptides
The present invention provides antigen-binding polypeptides (e.g., bi-specific antigen-binding polypeptides) that specifically bind to a first and a second...
US-1,020,2461 Anti-human TROP-2 antibody having an antitumor activity in vivo
The present invention provides: an antibody which specifically reacts with hTROP-2 and has anti-tumor activity in vivo (particularly, a humanized antibody); a...
US-1,020,2460 CD37-binding molecules and immunoconjugates thereof
Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to CD37 are provided. Methods of using the agents,...
US-1,020,2459 Methods of inhibiting pathological angiogenesis with doppel-targeting molecules
Described herein are doppel-targeting molecules useful for inhibiting pathological angiogenesis and treating diseases and conditions associated with...
US-1,020,2458 IGF-1R antibody and its use as addressing vehicle for the treatment of cancer
The present invention relates to an antibody, in particular a monoclonal antibody, capable of binding to IGF-1R, as well as the amino and nucleic acid sequences...
US-1,020,2457 Anti-DEspR monoclonal antibody targeted therapy and imaging for cancer and stroke
Provided herein are novel compositions comprising anti-DEspR antibodies and fragments thereof derived from 6G8G7 and 7C5B2 anti-DEspR variant antibodies,...
US-1,020,2456 Method for producing polypeptides using PDK-inactivated cells
Provided is a recombinant cell including inactivated pyruvate dehydrogenase kinase (PDK) gene, a composition for producing a polypeptide of interest including...
US-1,020,2455 Molecular constructs with targeting and effector moieties comprising an SCFV specific for ectodomain of...
The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using...
US-1,020,2454 Anti-PD-L1 monoclonal antibodies and fragments thereof
The present invention is based, in part, on the discovery of monoclonal antibodies that specifically bind to the cytoplasmic domain of PD-L1 antibodies useful...
US-1,020,2453 Antibody therapeutics that bind CTLA4
There is disclosed compositions and methods relating to or derived from anti-CTLA4 antibodies. More specifically, there is disclosed fully human antibodies that...
US-1,020,2452 CD3 binding polypeptides
The present invention relates to mono-specific and multi-specific polypeptides that specifically bind or interact with CD3. These polypeptides can be, but are...
US-1,020,2451 CD33 binding agents
The present invention relates to immunotherapies that are based on myeloid cell depletion. In particular, the present invention relates to CD33 binding agents...
US-1,020,2450 Na.sub.v 1.7 antibodies and methods of using the same
Disclosed herein is an antibody that binds to a voltage sensor paddle (VSP) of Nav1.7. Also disclosed herein are methods of treating pain, itch, neurogenic...
US-1,020,2449 Cachexia treatment
Administration of an antibody that specifically binds IL-1.alpha. is useful for treating cachexia and increasing the lifespan of a subject suffering from cachexia.
US-1,020,2448 Anti-IL-23 antibodies
The present invention relates to anti-IL-23p19 binding compounds, in particular new humanized anti-IL-23p19 antibodies and therapeutic and diagnostic methods...
US-1,020,2447 Antibody derivatives
The invention relates inter alia to a bivalent, bispecific construct comprising an anti-IL-6 antibody, or derivative thereof, and an anti-IL-23 antibody, or...
US-1,020,2446 Anti FGF23 antibody and a pharmaceutical composition comprising the same
To provide an antibody against FGF23 and a pharmaceutical composition such as a preventive or therapeutic agent which can prevent or treat by suppressing an...
US-1,020,2445 Method of providing disease-specific binding molecules and targets
Provided are novel specific binding molecules, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize neoepitopes...
US-1,020,2444 Anti-tau antibodies
The present invention relates, in part, to isolated antibodies that specifically interact with and show measurable binding affinity to an epitope of the tau...
US-1,020,2443 TDP-43-binding polypeptides useful for the treatment of neurodegenerative diseases
Provided herein are antigen-binding constructs such as antibodies that bind to the RRM-1 domain of TDP-43. The antigen-binding constructs are capable of...
US-1,020,2442 Antigen associated with lung cancers and lymphomas
The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of lung cancer and lymphoma.
US-1,020,2441 Methods, compositions and kits for treating a subject using a recombinant neutralizing binding protein
Methods, compositions and kits are provided for treating a subject exposed to or at risk for exposure to a disease agent using a pharmaceutical composition...
US-1,020,2440 Methods of treating and preventing Staphylococcus aureus infections and associated conditions
The present invention relates to methods and compositions for preventing and treating Staphylococcus aureus in a subject. Therapeutic compositions of the...
US-1,020,2439 Biological therapeutics for infection-relating disorders or conditions
The present invention discloses products and the methods of uses of the products for preventing and treating infectious diseases and the disorders or conditions...
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