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Patent # Description
US-1,020,1618 Alkenyl substituted 2,5-piperazinediones, compositions, and uses thereof
Provided herein are compounds of Formula (I), and salts thereof, wherein each instance of R.sup.L is independently optionally substituted C.sub.6-C.sub.40...
US-1,020,1617 3-substituted piperidine-2, 6-diones and non-covalent complexes with albumin
The present disclosure provides derivatives of 3-substituted piperidine-2, 6-diones, non-covalently bound complexes with serum albumin, pharmaceutical...
US-1,020,1616 Non-cleavable polymer conjugated with .alpha.V.beta.3 integrin thyroid antagonists
Chemical compositions and methods of synthesis thereof. The compositions disclosed and described herein are directed toward and classified as anti-angiogenic...
US-1,020,1615 Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway
The present invention is directed to methods for treating cancer comprising administering to a subject in need thereof an auristatin-based antibody drug...
US-1,020,1614 Cytotoxic and anti-mitotic compounds, and methods of using the same
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical...
US-1,020,1613 Method of creating hydrogels through oxime bond formation
A method of creating a hydrogel, comprising the step of condensing first and second functional groups, wherein the first group comprises a molecule or...
US-1,020,1612 Devices and methods for controlling headspace humidity and oxygen levels
A humidity control device for use in maintaining the desired humidity of a closed environment, e.g., a container, while also decreasing headspace oxygen, the...
US-1,020,1611 Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy
The present invention relates to a method of treating or preventing estrogen-sensitive tumours in a mammal, said method comprising the administration of a...
US-1,020,1610 Interference peptides and use thereof
A purified and isolated peptide comprises an amino acid sequence of SEQ ID NOs: 1 to 8. A method is also provided for preventing interaction, e.g. binding, of...
US-1,020,1609 Method for the production of a formulation of a hypericin salt
Photodynamic therapy of tumors such as bladder tumors includes photosensitizing with a photosensitizer that is a complex or a compound of hypericin and a...
US-1,020,1608 Polynucleotides encoding humanized anti-CD40 antibodies
The present disclosure relates to anti-CD40 antibodies, such as humanized anti-CD40 antibodies, that may be used in various therapeutic, prophylactic and...
US-1,020,1606 Combination immunotherapy of antigen-recognizing receptors and hematopoietic cells for the treatment of diseases
The invention provides a system that comprises pharmaceutical agents for use in immunotherapy for reducing the side-effects of an antigen-recognizing receptor...
US-1,020,1605 Gene-deleted variant strain of porcine pseudorabies virus, vaccine composition, method of making the same and...
The present invention provides an attenuated strain of porcine pseudorabies virus (PRV), in which said attenuated strain of PRV is a variant strain of PRV with...
US-1,020,1604 Live attenuated infectious laryngotracheitis virus (ILTV) vaccines and preparation thereof
This disclosure describes a modified live infectious laryngotracheitis virus (ILTV) developed from a strain of ILTV grown at a reduced incubation temperature,...
US-1,020,1603 Therapeutic compositions and methods for treating HIV including identification and manipulation of particular...
Selection of HIV vaccine antigens by use of intrapatient sequence variation to identify mutations in the HIV envelope glycoprotein that affect the binding of...
US-1,020,1602 Recombinant vaccine against PRRS in a viral vector
A live or inactivated recombinant vaccine is described, comprising a viral vector and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, wherein...
US-1,020,1601 Compositions and methods for increasing immunogenicity of glycoprotein vaccines
The present invention relates to the microbial immunogens engineered to bear .alpha.-gal epitope(s) for induction of potent humoral and cellular immune...
US-1,020,1600 Process for preparing an attenuated tetravalent dengue vaccine
The present invention refers to a process for preparing an attenuated tetravalent dengue vaccine and its product. The present invention also refers to a process...
US-1,020,1599 Immunogenic compositions comprising Lawsonia intracellularis
The present invention provides combination vaccines that comprise an immunological agent effective for reducing the incidence of or lessening the severity of...
US-1,020,1598 Synthetic immunogens for prophylaxis or treatment of tuberculosis
Compositions comprising a nucleic acid molecule that encodes TB esat-6 proteins are disclosed. Methods of inducing an immune response against TB an individual...
US-1,020,1597 Codon-optimized lentiviral vector for stem cell reprogramming
The invention relates to methods and materials that can be used to product cytotoxic T cells that target cancer cells expressing the cancer-testis antigen NY...
US-1,020,1596 Peptide conjugated particles for the treatment of allergy
The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles In particular, PLG particles are...
US-1,020,1595 C1-INH compositions and methods for the prevention and treatment of disorders associated with C1 esterase...
Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency are disclosed.
US-1,020,1594 Compositions and methods for safe treatment of rhinitis
Methods for treating rhinitis in a subject are provided herein. The methods of the present invention comprise intranasal administration of a topical composition...
US-1,020,1593 Method of treating gluten intolerance by means of new S8/S53 endopetidases from the actinomycete Actinoallomurus
The invention relates to a new family of proteolytic enxymes having the ability to hydrolize at a pH between 3 and 8 gluten olygopeptides which are resistant to...
US-1,020,1592 Compositions and methods for treating mesothelioma post-surgery
Cancer is a complex group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Described herein are...
US-1,020,1591 TSLP induces neutrophil mediated killing of methicillin-resistant staphylococcus aureus
The invention provides a method of promoting the host defense of a patient to a bacterial infection comprising administering to a patient suffering or at risk...
US-1,020,1590 Treatment of ocular disorders with anti-connexin proteins and mimetics
Methods and compositions for modulating the activities of connexins are provided, including, for example, for use for treatment of cardiovascular, vascular,...
US-1,020,1589 Compositions and methods for treating disease using Salmonella T3SS effector protein (SipA)
The invention provides compositions and methods for reducing one or more symptoms of disease by administering compositions comprising SipA. The invention's...
US-1,020,1588 Materials and methods of treating dyslipidemia
Described herein are materials and methods for treating dyslipidemia in a mammalian subject in need thereof comprising administering a growth hormone-releasing...
US-1,020,1587 Methods of inhibiting and treating biofilms using glycopeptide antibiotics
The present invention is directed to methods of inhibition, delay of formation, treatment, prophylaxis and/or prevention of infections caused by bacteria that...
US-1,020,1586 TFPI inhibitors and methods of use
The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may...
US-1,020,1585 Methods for treatment of atherosclerosis
Disclosed herein are methods and compositions for preventing or treating atherosclerosis in a mammalian subject. The methods comprise administering to the...
US-1,020,1584 Compositions and methods for treating HCV
This disclosure is directed to pharmaceutical compositions that comprise two or more therapeutic agents that, inter alia, are useful for inhibiting hepatitis C...
US-1,020,1583 Antioxidant dietary supplement and related method
A supplement including a blend of turmeric, quercetin and rosemary, or holy basil, wasabi, and broccoli seed extract which are present in a balanced and...
US-1,020,1582 Compositions and methods for alleviating hyposalivation and for providing oral comfort
Various compositions and methods are provided to alleviate one or more symptoms associated with hyposalivation and/or xerostomia. Preferred compositions and...
US-1,020,1581 Composition for cooling skin comprising phellodendron bark extract, method of preparing the same, topical...
Provided are a composition for cooling skin comprising a Phellodendron bark extract, a method of preparing the composition, a skin-improving product comprising...
US-1,020,1580 Methods of feeding animals liquid feed with soluble fiber and sugar alcohol
An animal feed such as a milk replacer includes a soluble fiber and a sugar alcohol. The milk replacer enhances weight gain, starter intake and reduces weaning...
US-1,020,1579 Compositions for reducing environmental sensitivity and regulating immune function
The present invention is directed to compositions for improving immune function and sensitivities to the natural and manmade environment that include...
US-1,020,1578 Pharmaceutical composition or health food comprising Lonicera caerulea var. edulis fruit extracts as active...
The present invention relates to a composition containing a fruit extract of Lonicera caerulea L. var. edulis as an active ingredient for the prevention and...
US-1,020,1577 Compositions and methods for enhancing working and long-term memory support using new combination of ginkgo...
A nutritional supplement composition and associated method enhances working and long term memory support in a healthy adult person, and includes a Panax Ginseng...
US-1,020,1576 Herbal composition for vaginal treatment
The present invention discloses a herbal formulation comprising therapeutic effective amount of plant extract of Woodfordia Floribunda; therapeutic effective...
US-1,020,1575 Oncolytic HSV vector
The present invention provides a recombinant oncolytic Herpes Simplex Virus (oHSV) comprising a non-HSV ligand specific for a molecule (protein, lipid, or...
US-1,020,1574 Methods of microbial treatment of poultry
Disclosed are methods of administering one or more Bacillus strains to poultry. The Bacillus strains improve bacterial homeostasis in the gastrointestinal tract...
US-1,020,1573 Human birth tissue material composition and methods for the treatment of damage associated with a cerebral...
Methods of treating vascular damage caused by a cerebral vascular accident in a subject are provided. The method includes the step of administering an effective...
US-1,020,1572 Combination therapy with double negative T-cells
There is provided herein methods of treating leukemia or lymphoma in a subject in need thereof, with double negative T cells (DNTs) in combination with...
US-1,020,1571 Nanoparticle compositions and methods for treating onychomychosis
A nanoparticle composition for treating onychomycosis includes spherical-shaped nanoparticles having a particle size and a particle size distribution and...
US-1,020,1570 Halogen treatment of heart attack and ischemic injury
The present invention relates to the use of halogen compounds, including iodide, and chalcogenide compounds, including iodide, sulfide and selenide, to treat...
US-1,020,1569 Pharmaceutical formulations for the treatment and prevention of trauma-induced neuropathology and neurodegeneration
Novel multi-component formulations, procedures and methods for use in treating neuropathology and neurodegeneration incident to trauma are provided....
US-1,020,1568 Brain, spinal, and nerve injury treatment
A treatment for brain, spinal and nerve injury comprising use of a substance P receptor antagonist optionally in combination with a magnesium compound. There is...
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