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Patent # Description
US-1,026,0073 Isolated polynucleotides and polypeptides, and methods of using same for increasing yield of plants
Provided are isolated polynucleotides and nucleic acid constructs which comprise a nucleic acid sequence at least 80% identical to a nucleic acid sequence...
US-1,026,0072 Compositions and methods for 3-hydroxypropionic acid production
The present application discloses genetically modified yeast cells comprising an active 3-HP fermentation pathway, and the use of these cells to produce 3-HP.
US-1,026,0071 CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity
The invention relates to oligonucleotides including at least one lipophilic substituted nucleotide analog and a pyrimidine-purine dinucleotide. The invention...
US-1,026,0070 Aptamer for NGF and use thereof
Provided are an aptamer having an inhibitory activity against NGF; a complex containing an aptamer having a binding activity or inhibitory activity against NGF...
US-1,026,0069 Selective antisense compounds and uses thereof
The present disclosure provides oligomeric compounds. Certain such oligomeric compounds are useful for hybridizing to a complementary nucleic acid, including...
US-1,026,0068 Prophylactic agent and therapeutic agent for fibrodysplasia ossificans progressiva
The invention provides a prophylactic agent or therapeutic agent for fibrodysplasia ossificans progressiva, containing as an active ingredient a binding...
US-1,026,0067 Enhancing dermal wound healing by downregulating microRNA-26a
Methods for enhancing wound healing, e.g., in diabetic subjects, by administering an antagonist of miR-26a, e.g., an inhibitory nucleic acid that targets miR-26a.
US-1,026,0066 Therapeutic alteration of transplantable tissues through in situ or ex vivo exposure to RNA interference molecules
The present invention, at least in part, relates to the discovery of efficacious delivery of an RNAi agent (in preferred aspects of the invention, an siRNA) to...
US-1,026,0065 Random RNA libraries, methods of generating same, and screening methods utilizing same
This invention provides sets and libraries of short hairpin ribonucleic acid (shRNA) molecules comprising a double-stranded region of random sequence containing...
US-1,026,0064 Programmed droplet rupture for directed evolution
A method of directed evolution screening includes selecting a protein expression platform for an evolution target, expressing a key rupture gene configured to...
US-1,026,0063 Enrichment of small nucleic acids
Provided herein is technology related to processing samples of nucleic acids and particularly, but not exclusively, to methods for enriching samples for small...
US-1,026,0062 Targeted genomic alteration
Disclosed herein are methods and compositions for targeted integration and/or targeted excision of one or more sequences into a cell, for example, for...
US-1,026,0061 Mesoporous catalysts of magnetic nanoparticles and free-radical-producing enzymes, and methods of use
A composition comprising mesoporous aggregates of magnetic nanoparticles and free-radical producing enzyme (i.e., enzyme-bound mesoporous aggregates), wherein...
US-1,026,0060 Genetically modified phenylpyruvate decarboxylase, processes to prepare, and uses thereof
Modification of the amino acid sequence of a phenylpyruvate decarboxylase from Azospirillum brasilense produces a novel group of phenylpyruvate decarboxylases...
US-1,026,0059 Nitrilase from arabis alpina, its encoding gene, vector, recombinant bacterial strain and uses thereof
The disclosure provides a nitrilase from Arabis alpina, which belongs to genus Arabis, family brassicaceae. The disclosure further provides the encoding gene,...
US-1,026,0058 Beta-glucosidase variants polynucleotides encoding same
The present invention relates to beta-glucosidase variants, e.g., beta-glucosidase variants of a parent Family GH3A beta-glucosidase from Aspergillus fumigatus....
US-1,026,0057 Thermostable cellobiohydrolase
A thermostable cellobiohydrolase, having a cellobiohydrolase catalytic domain including: (A) a polypeptide including the amino acid sequence represented by SEQ...
US-1,026,0056 Cleavage of fucose in N-glycans
Provided herein is an .alpha.-fucosidase that can cleave a conjugate comprising an N-glycan and a label where the label is added by amine reactive chemistry....
US-1,026,0055 Delivery of cargo proteins via ARRDC1-mediated microvesicles (ARMMs)
Methods, systems, compositions and strategies for the delivery of WW domain-containing fusion proteins into cells in vivo, ex vivo, or in vitro via ARMMs are...
US-1,026,0054 Engineered organophosphorus acid anhydrolases and methods of use thereof
Genetically engineered organophosphorus acid anhydrolases (OPAA) with improved catalytic efficiency and relaxed stereospecificity are provided. The variants...
US-1,026,0053 Glucosyltransferase enzymes for production of glucan polymers
Compositions are disclosed herein comprising poly alpha-1,3-1,6-glucan with a weight average degree of polymerization (DP.sub.w) of at least 1000. This glucan...
US-1,026,0052 Diacylgylcerol acyl transferase (DGA1) polynucleotides, and methods of increasing yeast cell lipid production...
DGA1 catalyzes the final enzymatic step for converting acyl-CoA and 1,2-diacylglycerol to triacylglycerols (TAG) and CoA in yeast. Disclosed are methods for...
US-1,026,0051 Phage therapy of Pseudomonas infections
The present invention relates to bacteriophage therapy. More particularly, the present invention relates to novel bacteriophages having a high specificity...
US-1,026,0050 Methods of producing and characterizing virus vaccine and virus vaccine composition
This application pertains to methods of isolating virus particles and producing virus vaccine composition comprising subject a biological sample to an anion...
US-1,026,0049 Attenuated reovirus
Compositions and methods are provided that relate to an attenuated reovirus exhibiting oncolytic activity toward cancer cells while displaying reduced lytic...
US-1,026,0048 Generation of induced pluripotent stem cells from small volumes of peripheral blood
Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may...
US-1,026,0047 Angiohematopoietic progenitor cells
A purified human cell population of subsets of angiohematopoietic progenitor cells, wherein the population is at least 94% pure and wherein the cells are...
US-1,026,0046 Methods for reprogramming cells and uses thereof
A method of obtaining a cardiac multipotent or unipotent cell, comprising: i) providing a cell of a first type which is not a cardiac multipotent or unipotent...
US-1,026,0045 Use of collagen type VII for maintaining and re-inducing osteogenic abilities of mesenchymal stem cells
This invention provides methods of inducing and maintaining osteogenic potential in mesenchymal stem cells and compositions for doing the same. The compositions...
US-1,026,0044 Methods of expanding myeloid cell populations and uses thereof
The present disclosure relates to a method of expanding myeloid progenitor cells by culturing an initial population of cells in a medium comprising a mixture of...
US-1,026,0043 Human extensively self-renewing erythroblasts (ESRE)
The present invention provides a human cell population that can self-renew extensively and yet retain the capacity to differentiate into red blood cells (RBCs)....
US-1,026,0042 Compositions and methods for diminishing an immune response
The invention is based upon the discovery that T regulatory type 1 (Tr1) cells express particular cell surface markers that allow for their selection,...
US-1,026,0041 Methods for neural conversion of human embryonic stem cells
The present invention relates generally to the field of cell biology of stem cells, more specifically the directed differentiation of pluripotent or multipotent...
US-1,026,0038 Protein modification of living cells using sortase
Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to...
US-1,026,0037 System and method to divide liposuction fat into aliquots
A system (1) to divide liposuction fat into aliquots, comprising taking means (2, 3) to take from a container a quantity of adipose material, made available by...
US-1,026,0036 Mixing and filtering system and method
An apparatus for growing and separating cells or micro carriers from fluid medium in an aseptic environment, has a sealed, air and liquid tight, container...
US-1,026,0035 Cell stimulating system
Provided is a cell stimulating system including an oscillator, in an ultrasound probe array type, including a plurality of ultrasound devices disposed in a...
US-1,026,0034 Culture flask
A culture flask comprising a culture chamber in a flask body comprising an even bottom wall with a growth surface on the top side, an even cover wall at a...
US-1,026,0033 Method and apparatus to mitigate evaporation in high throughput measurements
A method and apparatus are disclosed for the collection of light scattered from a liquid sample contained within a multiwell plate for which evaporation from...
US-1,026,0032 Apparatus and method for aging liquids
Arrays of closely-spaced holes or cross-grain grooves are formed on the inside surfaces of the staves of a barrel, and/or on an elongated wooden member to...
US-1,026,0031 Optimized dewatering process for an agricultural production facility
This disclosure describes techniques to optimize dewatering process in a production facility. A process separates components in a mixture by using a separation...
US-1,026,0030 Disposable wipes with peracetic acid treatment agent
A disposable, single-use wipe that can be used deodorize, disinfect, and/or sterilize an object. A holder may be used to create or energize one or more...
US-1,026,0029 Process for washing fabrics
The present invention comprises a process of washing fabrics using a water-soluble unit dose article.
US-1,026,0028 Process for making soap bar having separate regions of specifically selected components
The present invention relates to a process for making soap bar compositions comprising bar matrix comprising predominantly long chain length soap and...
US-1,026,0027 Substrate detergent composition
The invention provides a substrate detergent composition used for cleaning a surface of a substrate, comprising: (A) A quaternary ammonium salt: 0.1 to 2.0% by...
US-1,026,0026 Method for dissolution of polymerized soil
A method for removing polymerized soil by adding to the soil a composition which includes: (a) from 4 to 30 wt % of a hydroxide or alkoxide, (b) from 10 to 96...
US-1,026,0025 Use of activator complexes to enhance lower temperature cleaning in alkaline peroxide cleaning systems
The present invention provides for the use of activator complexes to enhance lower temperature cleaning in alkaline peroxide cleaning systems. Compositions...
US-1,026,0024 Liquid cleaning compositions comprising protease variants
The present invention relates to compositions comprising protease variants suitable for use in cleaning or detergent compositions, such as laundry detergent...
US-1,026,0023 Preparation of functionalized castor oil derivatives using solid acid and base catalysts
This invention relates to the development of processes for the preparation of functionalized castor oil derivatives namely ring-opened glyceryl ricinoleates,...
US-1,026,0022 Microcapsules imparting intense vanilla odor note
The present invention relates to microcapsules delivering long lasting and intense vanilla-based odor note. More particularly, the present invention concerns a...
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