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Patent # Description
US-1,027,2114 Peptides and scaffolds for use in immunotherapy against head and neck squamous cell carcinoma and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,027,2112 Microsphere-based delivery and ex vivo manipulation of dendritic cells for autoimmune therapies
The present invention relates to tolerogenic mammalian dendritic cells (iDCs) and methods for the production of tolerogenic DCs. In addition, the present...
US-1,027,2111 Induced dendritic cells and uses thereof
The present invention relates to cells engineered to express at least one cytokine and at least one antigen which induces the self differentiation of dendritic...
US-1,027,2110 Methods for promoting HSC engraftment
The present invention provides for compositions and methods for modulating hematopoetic stem cell populations by using HCS modulators, which are agents that...
US-1,027,2109 Organs for transplantation
The invention provides methods and compositions that improve the success of organ transplantation. The methods and compositions are directed to exposing a...
US-1,027,2108 Antimicrobial silver hydrogel composition for the treatment of burns and wounds
An antimicrobial therapeutic hydrogel composition comprises a pharmaceutical and/or medical grade silver salt, and an Aloe vera gel or extract. The composition...
US-1,027,2107 Method for treating inflammatory brain disorders and traumatic brain injury
The present invention provides methods for treating an inflammatory brain disease and for treating a traumatic brain injury in a human having an inflammatory...
US-1,027,2106 Compositions and methods of treating diabetic retinopathy
A method of treating diabetic retinopathy in a subject in need thereof includes administering to the subject a therapeutically effective amount of one or more...
US-1,027,2105 Plant medium including an oxygen-enabled composition
A composition including a plant medium and a poly-oxygenated metal hydroxide that comprises a clathrate containing oxygen gas molecules. The poly-oxygenated...
US-1,027,2104 Method for treating itch
The present invention is anti-itching powder that blocks transmission to stratum corneum and invasion up to epidermal cells by emulsion as a result of further...
US-1,027,2103 Crosslinked polyvinylamine, polyallylamine, and polyethyleneimine for use as bile acid sequestrants
The present invention provides a crosslinked amine and amide polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile...
US-1,027,2102 Hydroxyalkyl starch for the treatment of hematological neoplasms
The present invention relates to hydroxyalkyl starch or a pharmaceutical preparation thereof for the treatment of a hematological neoplasm, especially by...
US-1,027,2101 Glucan preparations
Particulate .beta.-glucan is solubilized at elevated pressure and temperature to form soluble .beta.-glucan. The method is safe and economical and produces a...
US-1,027,2100 Non-reducing end unsaturated mannuronic acid oligosaccharides and compositions containing same as active ingredient
Disclosed is a non-reducing end unsaturated mannuronic acid oligosaccharide having a molecular weight of 100-3000 Da, which is obtained by lysing...
US-1,027,2099 Tumor-selective combination therapy
The therapies described herein can be selectively lethal toward a variety of different cancer cell types and cancer conditions in a subject. The combination...
US-1,027,2098 Chelated drug delivery systems
The present invention provides drug delivery compositions that allow for immediate and/or sustained release of a therapeutic agent contained within the system....
US-1,027,2097 Uses of oxygenated cholesterol sulfates (OCS)
Methods of preventing and/or treating ischemia, organ dysfunction and/or organ failure, including multiple organ dysfunction syndrome (MODS), and necrosis and...
US-1,027,2096 Methods and systems of treating wounds
The invention generally relates to methods for treating and/or reducing the severity of a wound in a subject. Provided are wound therapies combining low level...
US-1,027,2095 NRF2 regulators
The present invention relates to aryl analogs, pharmaceutical compositions containing them and their use as NRF2 regulators.
US-1,027,2094 5-HT2C receptor agonists and compositions and methods of use
Provided in some embodiments are compounds of Formula A, as defined herein, that modulate the activity of 5-HT2C receptor. Also provided in some embodiments are...
US-1,027,2093 Use of H3K9me3 modulation for enhancing cognitive function
Use of H3K9me3 modulation for enhancing cognitive function and treating anxiety related disorders is presented. A composition is administered to the subject...
US-1,027,2092 Composition for preventing or treating mucositis comprising NecroX as effective ingredient
The present invention relates to a composition for preventing or treating mucositis comprising NecroX. It was found that NecroX has effects of reducing the...
US-1,027,2091 Theacrine-based supplement and method of use thereof
A human dietary supplement comprises theacrine and optionally other compounds that modulate the effects of theacrine. Uses for the theacrine-containing...
US-1,027,2090 Liquid pharmaceutical composition comprising pemetrexed
The present invention relates to a liquid pharmaceutical composition suitable for parenteral administration comprising: a) pemetrexed diacid; b) at least one...
US-1,027,2089 Methotrexate for proliferative vitreoretinopathy
The use of methotrexate, e.g., repeated dosing or sustained-release formulations of methotrexate, for treating or reducing risk of proliferative...
US-1,027,2088 FAS inhibitors and methods associated therewith
The present invention relates to compounds, compositions and methods comprising nanoparticles (NP) that are based on hyaluronic acid (HLA) that have been...
US-1,027,2087 Pteridines as FGFR inhibitors
The invention relates to new pteridine derivative compounds, of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the...
US-1,027,2086 Minoxidil for suppressing androgen receptor function
Methods for treating androgen receptor related diseases and suppressing androgen receptor related function by administering an effective amount of minoxidil are...
US-1,027,2085 Pyrimidine derivatives for the treatment of viral infections
This invention relates to pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections such...
US-1,027,2084 Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy
Disclosed are methods for treating cisplatin-induced peripheral neuropathy in a subject in need thereof comprising administering to the subject a...
US-1,027,2083 Methods of treating chronic lymphocytic leukemia and small lymphocytic leukemia using a BTK inhibitor
Therapeutic methods of treating chronic lymphocytic leukemia (CLL) and small lymphocytic leukemia (SLL) are described. In certain embodiments, the invention...
US-1,027,2082 Combination ALS therapy
Provided is a method for treating ALS in a subject, comprising administering to the subject a therapeutically effective amount of riluzole and a therapeutically...
US-1,027,2081 SHIP1 modulators and methods related thereto
Compounds of formula (I): ##STR00001## where ##STR00002## n, R.sup.1, R.sup.4a, R.sup.4b, R.sup.5, R.sup.7 and R.sup.8 are defined herein, or ...
US-1,027,2080 Selective dopamine D4 receptor agonists for treatment of working memory deficits
Working memory deficits are treated and working memory is improved with a composition that comprises a therapeutically effective amount of one or more...
US-1,027,2079 NHE3-binding compounds and methods for inhibiting phosphate transport
Provided are NHE3-binding and/or NHE3-modulating agents having activity as phosphate transport inhibitors, including inhibitors of phosphate transport in the...
US-1,027,2078 Crystalline forms of a prolyl hydroxylase inhibitor
The present disclosure relates to crystalline solid forms of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid, the process of...
US-1,027,2077 Piperidinone carboxamide azaindane CGRP receptor antagonists
The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or...
US-1,027,2076 Methods for the administration of iloperidone
The present invention relates to methods for the identification of genetic polymorphisms that may be associated with a risk for QT prolongation after treatment...
US-1,027,2075 Method and composition for treating an alpha adrenoceptor-mediated condition
Methods and compositions for the treatment of alpha-adrenoceptor mediated conditions.
US-1,027,2074 Inhibitors of glucocorticoid receptor translocation
Provided herein are compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of...
US-1,027,2073 Apparatus and methods for preventing or treating failure of hemodialysis vascular access and other vascular grafts
This invention is a prosthetic device generally placed on the outside surface of the vessel or graft which then elutes antiproliferative drugs or agents from a...
US-1,027,2072 Compounds and compositions for the inhibition of NAMPT
The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound...
US-1,027,2071 Use of isoxazoline derivatives for the treatment or prevention of arthropod infestations in poultry
The present invention relates to methods of treating or preventing arthropod infestations of poultry animals and methods of controlling arthropod infestations...
US-1,027,2070 Method for treating neurodegenerative diseases
The present invention is directed to a method for treating a neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer disease,...
US-1,027,2069 Methods of treating muscular dystrophy
Disclosed herein are .alpha.7.beta.1 integrin modulatory agents and methods of using such to treat conditions associated with decreased .alpha.7.beta.1 integrin...
US-1,027,2068 Pharmaceutical compositions and methods
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof a p450 3A4 promoter; and...
US-1,027,2067 Pyrrolidone carboxylic acid (PCA) for ophthalmic use
The present invention relates to pyrrolidone carboxylic acid (PCA) and/or pharmaceutically acceptable salts or derivatives thereof for use in the treatment of...
US-1,027,2066 Compounds for the treatment of diseases linked to mitochondrial reactive oxygen species (ROS) production
The present invention relates to the use of compounds for the prevention and treatment of diseases whose initiation and/or evolution relates to the production...
US-1,027,2065 Gem-difluorinated C-glycoside compounds as anti-cancer agents
The present document describes a synthesis of a class of gem-difluorinated C-glycoside compounds derived from podophyllotoxin, which may be used, but not...
US-1,027,2064 Pharmaceutical formulations for subcutaneous administration of furosemide
The present teachings relate to liquid pharmaceutical formulations of furosemide, where the pharmaceutical formulations include a molar excess of...
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