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Patent # Description
US-1,028,6007 Use of pre T alpha or functional variant thereof for expanding TCR alpha deficient T cells
A method of expanding TCRalpha deficient T-cells by expressing pTalpha or functional variants thereof into said cells, thereby restoring a functional CD3...
US-1,028,6006 Trace elements
A trace element solution comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one...
US-1,028,6005 Antioxidant agent, and antioxidant cosmetic and UV care cosmetic
The present invention provides an antioxidant, an ROS inhibitor, an antioxidant enzyme production promoter, an antioxidant cosmetic, a UV care cosmetic, a...
US-1,028,6004 Targeting-enhanced anticancer nanoparticles and preparation methods of same
Targeting-enhanced anticancer nanoparticles and preparation methods for the nanoparticles are provided. In particular, this invention provides ...
US-1,028,6003 Injectable antibiotic formulations and use thereof
Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin. In particular, compositions...
US-1,028,6002 Application of a phillyrin/phillygeninin composition in preparing a medicine or health care product for...
The present invention discloses a new application of a composition of phillyrin and phillygeninin in the preparation of drugs for alleviating or/and treating...
US-1,028,6001 Use of purified 2'-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics
The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
US-1,028,6000 Retinoid X receptor-gamma agonists and retinoid X receptor-alpha antagonists for treatment of cancer
The invention is directed to the use of Retinoid X Receptor-gamma (RXR-gamma) agonists and Retinoid X Receptor-alpha (RXR-alpha) antagonists in treatment of...
US-1,028,5998 Composition and method to aid in hormone replacement therapy
A pharmaceutical two-phase admixture for topical application, transdermal or transmucosal, characterized by components in two phases, a liquid and a solid,...
US-1,028,5997 Treatment of skin atrophy with a combination of triiodothyroacetic acid (TRIAC) and dehydroepiandrosterone (DHEA)
The aim of the present study was to investigate the effect of a combination of triiodothyroacetic acid (TRIAC) and dehydroepiandrosterone (DHEA) compared with...
US-1,028,5996 Compositions comprising triterpenoids
The invention relates to compositions and formulations comprising at least one triterpenoic acid and at least one neutral triterpenoid and uses thereof for...
US-1,028,5995 Compositions and methods for reducing body fat
The present invention relates to compositions, such as bimatoprost, latanoprost and travoprost, and methods to reduce fat in the body of an individual, for...
US-1,028,5994 Method of preventing or treating osteoporosis by neddylation inhibitor
Disclosed herein is a method of preventing and/or treating abnormal bone resorption and/or osteoporosis in a subject in need thereof. The method comprises...
US-1,028,5993 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyri- ...
A novel crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrim- idin-3-yl)-3-hydroxypyrrolidine-1-carboxamide,...
US-1,028,5992 Combinations of PDE1 inhibitors and NEP inhibitors and associated methods
The invention relates to the combination of inhibitors of phosphodiesterase 1 (PDE1) and inhibitors of Neprilysin (NEP) useful for the treatment of certain...
US-1,028,5991 Therapeutic compounds and uses thereof
Described herein are compounds of Formula (I)-(III), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided are...
US-1,028,5990 Toll like receptor modulator compounds
The present disclosure relates generally to toll like receptor modulator compounds, such as diamino pyrido[3,2 D] pyrimidine compounds and pharmaceutical...
US-1,028,5989 Pyrimidinone amide compounds as PDE2 inhibitors
The present invention is directed to pyrimidinone amide compounds which may be useful as therapeutic agents for the treatment of central nervous system and/or...
US-1,028,5987 Device and kit for dosing and dispensing non-liquid medicine
A device for dosing and dispensing a dose of a non-liquid medicine that comprises a body connectable to a container containing an amount of a non-liquid...
US-1,028,5986 Compounds and anti-tumor NQO1 substrates
Compositions comprising Formula (I) can be selectively lethal toward a variety of different cancer cell types. The compositions are useful for the management,...
US-1,028,5985 Pharmaceutical composition for treatment or prevention of neurodegenerative diseases
There is provided a pharmaceutical composition for treatment or prevention of a neurodegenerative disease, comprising an RXR agonist as an active ingredient,...
US-1,028,5984 Methods and compositions for improving gut microbiota population
A method and a composition for improving gut micro biota structure, selectively increase a first gut microbiota population while simultaneously decrease a...
US-1,028,5983 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof
7-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a...
US-1,028,5982 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
6-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a...
US-1,028,5981 Compositions and methods for treating amyotrophic lateral sclerosis in responders
A method for treating amyotrophic lateral sclerosis (ALS) in a subject in need thereof comprising administering to said subject an effective amount of...
US-1,028,5980 Compositions for an orally active 1,2,4-oxadiazole for the treatment of disease
The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases...
US-1,028,5979 Breast cancer therapeutic agent containing 5'-hydroxy-5-nitro-indirubin-3'-oxime as active ingredient
A breast cancer therapeutic agent containing 5'-hydroxy-5-nitro-indirubin-3'-oxime as active ingredient has been disclosed. Further, a breast cancer therapeutic...
US-1,028,5978 Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio
A structurally distinct and potent series of synthetic small molecule activators of Vibrio cholerae quorum sensing have been chemically synthesized. The small...
US-1,028,5977 Compositions and methods for treating alopecia
The present invention is directed to a composition for treating alopecia containing minoxidil, cyclosporine A and a compound that binds FK506 binding protein 4...
US-1,028,5976 4-methylumbelliferone treatment for immune modulation
Compositions for treating autoimmune, allergic, or atopic disease comprising a compound that inhibits hyaluronan synthesis and a pharmaceutically acceptable...
US-1,028,5973 SGLT-2 inhibitors for treating metabolic disorders in patients with renal impairment or chronic kidney disease
The present invention relates to certain SGLT-2 inhibitors, such as ertugliflozin or a co-crystal or a pharmaceutically acceptable salt thereof, for treating...
US-1,028,5972 Trans-2-nonadecyl-4-hydroxymethyl-1,3-dioxolane and producing methodthereof
The present invention discloses a method for producing trans-2-nonadecyl-4-hydroxymethyl-1,3-dioxolane comprising mixing alkanes and pyridinium chlorochromat...
US-1,028,5971 Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders...
Provided herein are compositions that contain water-soluble vitamin E derivative mixtures (compositions), such as tocopheryl polyethylene glycol succinate...
US-1,028,5970 Method of treating endothelial dysfunction with oenothein B and proanthocyanidins
The present application concerns compositions comprising ellagitannins and proanthocyanidins, and the use of such compositions for preventing or treating...
US-1,028,5969 Mangiferin-6-O-berberine salt and preparation method and use thereof
The present invention provides a mangiferin-6-O-berberine salt and a preparation method thereof, and further provides a use of the mangiferin-6-O-berberine salt...
US-1,028,5968 Drug eluting expandable devices
The present disclosure relates to drug eluting devices, and their uses. The drug eluting devices can allow for perfusion during deployment. The coatings the may...
US-1,028,5967 Monoacylglycerols for use in conjunction with a lipase inhibitor and/or diets low in fat and/or calories
In an embodiment, compositions comprising monoacylglycerols (MAG), such as sn-1 MAG, are administered with a lipase inhibitor, such as tetrahydrolipstatin,...
US-1,028,5966 10-hydroxy-cis-12-octadecenoic acid alkyl ester and use thereof
The invention provides a HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use...
US-1,028,5965 Method for supplementing and administering a concentrated liquid diet
The concentrated liquid diet disclosed is a concentrated liquid diet having a total amount of a medium-chain fatty acid having 8 carbon atoms and a medium-chain...
US-1,028,5964 Fatty-acid based particles
The present invention is directed toward fatty acid-based particles, and methods of making such particles. The particles can be associated with an additional,...
US-1,028,5963 Combination of metabolic bio-energetic and nutra-epigentic regulators, nutraceutical compounds in conventional...
The invention relates to compounds of natural origin and their pharmaceutically acceptable and active mixture to decrease glucose, cholesterol, uric acid, and...
US-1,028,5962 Glutarate compounds for treating ischemia-reperfusion injuries
Disclosed herein are methods of preventing, inhibiting, reducing, or treating ischemia and reperfusion injury to tissues with glutarate compounds such as...
US-1,028,5961 Organic acids as agents to dissolve calcium minerals in pathological calcification and uses thereof
In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth...
US-1,028,5960 Autoimmune disorder treatment using RXR agonists
The present specification provides RXR agonist compounds, compositions comprising such RXR agonists, and methods using such compounds and compositions to treat...
US-1,028,5959 Combination therapies using HDAC inhibitors
The present invention pertains to a method for treating cancer, such as lung cancer, multiple myeloma, lymphoma, and epithelial ovarian cancer, comprising the...
US-1,028,5958 Genotype- or phenotype-based drug formulation
The invention relates to a combination of two or more pharmaceutically active substances, of which at least one is a metabolic product ("metabolite") of the...
US-1,028,5957 Epinephrine-based ophthalmic compositions for intraocular administration and methods for fabricating thereof
Pharmaceutical compositions for intraocular injection are described, the compositions comprise therapeutically effective quantity of lyophilized ...
US-1,028,5956 N-(2-aminoethyl) ethanolamine (AEEA) and analogs to treat hypertrophic scarring and liposomal topical delivery
The present invention includes pharmaceutical liposome formulation thereof comprising a N-(2-aminoethyl) ethanolamine (AEEA) and/or active analogs thereof in a...
US-1,028,5955 Affinity medicant conjugate
In an embodiment of the invention, a composition for treating a cell population comprises an Affinity Medicant Conjugate (AMC). The medicant moiety can be a...
US-1,028,5954 Topical use of an antimicrobial formulation
The present document describes a method of preventing or treating a hoof bacterial infection on at least one hoof of a live hoofed animal having a bacterial...
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