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Patent # Description
US-5,374,649 Indole derivatives and pharmaceutical use thereof
The invention relates to compounds of formula I. ##STR1## or a salt, or metabolically labile ester thereof wherein A represents an unsubstituted ethenyl,...
US-5,374,648 Indole derivatives and pharmaceutical use thereof
The invention relates to compounds of formula (I). ##STR1## or a salt, or metabolically labile ester thereof wherein R represents a group selected from...
US-5,374,416 Nitrogenous macrocyclic ligands, polymetallic complexes and diagnostic and therapeutic composition
The invention relates to ligands of formula ##STR1## in which B represents an ##STR2## W representing the ##STR3## group, in which groups X...
US-5,374,414 Self-supporting diamond filaments
Filamentous substrates are coated with diamond by a chemical vapor deposin process. The substrate may then be etched away to form a diamond filament. In a...
US-5,374,335 Sized paper, process for producing same and use thereof
The present invention relates to a sized paper containing a hydrophobic zeolite. Suitably, the sized paper is fine paper, kraft liner or paperboard. In...
US-5,374,255 Needle cover asssembly for syringes
The present invention is an improved needle cover assembly for a syringe. The needle cover assembly includes a first half and an opposite unequal second half...
US-5,373,018 Indole derivatives and pharmaceutical use thereof
The invention relates to the compound of formula (I) ##STR1## wherein A represents an unsubstituted ethenyl group in the trans (E) configuration or a...
US-5,372,863 Laminate-tube container improved in barrier property at shoulder thereof
A laminate-tube container having a shoulder with improved barrier properties is characterized in that the shoulder comprises a material composed of (A) 0 to 50%...
US-5,372,815 Medicinal compositions for use as a skin moisturizer and the treatment of exzema
A skin moisturizing medicinal preparation composition comprising Bismuth nitrate, salicylic acid, Catina oil and Rostopasca plant extracts. The composition...
US-5,372,814 Sterol derivative, process for producing the same and dermatologic external preparation
A sterol derivative represented by the general formulas (I) or (II) which is widely usable as the external base for the skin, emulsifier, etc., for cosmetics,...
US-5,372,276 Automatic pill dispenser
The progress of medicine has brought with it the presence of many potent pills that are to be taken with a great accuracy. If these medications are not taken as...
US-5,372,258 Pill sample illustrator, and weekly medicine box
A pill sample illustrator has a two rectangular, transparent plastic sheets that come together to enclose pill samples and a medical chart. These sheets provide...
US-5,371,204 Gene that encodes for polypeptides of IL-1.alpha.
An interleukin-1.alpha. (IL-1.alpha.) derivative having a modified amino acid sequence of IL-1.alpha., a gene coding for said derivative, medicinal composition...
US-5,371,107 Use of ascorbic acid in the genital area and corresponding medicinal preparations
A method of treating conditions of amine vaginitis, purulent vaginitis and dysplasia of the mouth of the uterus resulting from papilloma virus infection in the...
US-5,371,103 Thiochroman compounds
The invention relates to compounds of the formula I: ##STR1## in which R.sub.1 is as defined in the description, their optical isomers and their addition...
US-5,371,071 Peptide and pseudopeptide compounds which are therapeutically active in the blood coagulation cascade
The invention relates to the compounds of formula (I): in which X, A.sub.1, A.sub.2, A.sub.3, A.sub.4, A.sub.5, A.sub.6, A.sub.7, A.sub.8, A.sub.9, A.sub.10 and Y are...
US-5,370,629 Injection device
The invention concerns an injection device (1) receiving in exchangeable manner an ampoule (4) with a plunger (5) and an injection needle (6). It further...
US-5,369,943 Equipment for providing a medicine rod with a shell
The invention relates to providing a medicinal rod with a shell. The shell is formed from a hose, which is expanded by pressurizing its inner space. The...
US-5,369,004 Five highly informative microsatellite repeat polymorphic DNA markers
The invention relates to polymorphic markers (two tetranucleotide, one dinucleotide repeat polymorphisms, 27 markers characterized by primer pairs 1A-27A, and...
US-5,366,454 Implantable medication dispensing device
A medication dispensing device for implantation into an animal or human body, comprises a plurality of compartments each containing a dose of medicine to be...
US-5,365,930 Apparatus for measuring and evaluating blood circulation
An apparatus for observing and evaluating blood circulation utilizing pressure sensors disposed along an artery. Three pressure sensors may be used to detect...
US-5,364,775 Process for producing trans-L-hydroxyproline
The present invention provides a process for producing trans-L-hydroxyproline, which comprises culturing a microorganism which is capable of decomposing amino...
US-5,364,644 Formula and method for the prevention and treatment of hypercholesterolemia and cellular hyperproliferative...
The present invention provides a formula and method for the prevention and treatment of hypercholesterolemia and cellular hyperproliferation. More specifically,...
US-5,364,632 Medicinal emulsions
A pharmaceutical composition being an oil in water type emulsion which comprises an effective amount of a lypophilic drug is provided. The composition comprises...
US-5,364,362 Front syringe attachment for hypodermic syringes for subcutaneous injection in veterinary medicine
A front syringe attachment is provided for mounting on a syringe cylinder of hypodermic syringes for subcutaneous injection, particularly for use in veterinary...
US-5,364,356 Sleeve catheter
In a sleeve catheter for supplying medicine to the walls of a vessel or tubular organ in which a number of outer lumina extend longitudinally around a central...
US-D352,397 Medicine applying pet brush
US-5,362,858 Polyethylene glycol-hirudin conjugates, process for preparing them and their use for the treatment of thromboses
The present invention relates to a process for preparing a polyethylene glycol (or derivatives)-hirudin conjugate. It also relates to the polyethylene glycol (or...
US-5,360,896 Glycosylated FGF
Disclosed are (1) a mutein of a fibroblast growth factor (FGF), the DNA having introduced therein at least one nucleotide sequence coding for a glycosylation...
US-5,360,822 Sulfonanilide derivatives and medicine
An object of the present invention is to offer an agent for curing urinary incontinence with high selectivity for the urethra. One of the compounds of the present...
US-5,360,799 Substituted thienyl- or pyrrolylcarboxyclic acid derivatives, their preparation and medicines containing them
Compounds of formula ##STR1## in which R.sub.1 represents OH, (C.sub.1 -C.sub.12)alkyl, (C.sub.1 -C.sub.12)alkoxy, benzyloxy, benzyl, phenyl, (C.sub.1 ...
US-5,360,616 Injectable pharmaceutical composition
Formulations of programmed-release medicinal products intended for parenteral administration by injection, comprising calibrated solid microspheres (1 to 300...
US-5,360,411 Liquid medicine injecting device
A liquid medicine injecting device for constantly feeding a liquid medicine into a human body at a certain degree. The liquid medicine stored in a liquid...
US-5,359,097 Process for preparation of glycidyl ether
A process is provided for preparation of a glycidyl ether represented by the general formula ##STR1## wherein A represents an aryl group optionally having a...
US-5,358,937 Glycosyl phospholipid derivatives of nucleosides and their use as medicines
The glycosylphospholipid nucleoside derivatives of the invention are based on the formula: ##STR1## wherein: R.sub.1 is a nucleoside derivative selected...
US-5,358,501 Storage bottle containing a constituent of a medicinal solution
The storage bottle (10) contains a component of a medicinal solution (13) and a transfer device (11) for transferring it, after mixture with a solvent, into a...
US-5,358,489 Reloadable automatic or manual emergency injection system
A reloadable medicine injection apparatus having a barrel which receives a replaceable, disposable syringe subassembly. The syringe subassembly includes a...
US-5,358,117 Medicine container cap with time indicator
A device suitable as a closure cap for a medicine container is provided. The device has indicia circumferentially marked on the upper surface of the device...
US-5,356,916 1,2,4-oxadiazole derivatives having monoamine oxidase B enzyme-inhibitory activity
A 1,2,4-oxadiazole derivative is represented by the following general formula (I): ##STR1## wherein R.sup.1 represents a lower alkyl or cycloalkyl group, a...
US-5,356,406 Adaptor to facilitate interconnection of medicine bottle and syringe
For interconnecting a syringe with a barrel and needle to a bottle of medicine wherein the bottle has a generally cylindrical cap with a central target zone of...
US-5,354,913 Optically active phenol derivatives and preparation thereof
An optically active tri-substituted methane compound having, as substituents, an aromatic ring group and a phenyl group having hydroxyl group at ortho or para...
US-5,354,753 Methotrexate derivative
Disclosed is a compound represented by the formula: ##STR1## wherein R.sup.1 : CH.sub.2, CH.sub.2 CH.sub.2, CH.sub.2 O, CH.sub.2 S, CH.sub.2 SO; R.sup.2 :...
US-5,354,563 Water dispersion containing ultrafine particles of organic compounds
A water-dispersible condensate of water-insoluble ultrafine particles of medicine or hormones having a particle size of at largest 4 .mu.m prepared by the steps...
US-5,354,279 Plural needle injection catheter
A catheter for the injection of a fluid, for example, medicine, into body cavities such as veins or other hollow organs is provided with a head which is...
US-5,351,819 Sleep therapy package
A package for dispensing items for use in sleep therapy comprising a box having two compartments and a lid, packs of doses of sleep inducing medicine in one...
US-5,351,818 Medicine box
The box is rectangular and has a hinged lid for opening and closing the top. The bottom of the box has storage space for pill bottles and above this storage...
US-5,351,683 Device for the administration of powdered medicinal substances
An inhaler for the local administration of powdered drugs to the respiratory tract. The inhaler includes a nozzle and a main body which itself defines a storage...
US-5,349,190 Adjustable triple-detector image data acquisition system
An image data acquisition system for performing SPECT imaging and other types of imaging used in nuclear medicine includes an assembly of three detectors and a...
US-5,349,107 Process for producing optically active .gamma.-hydroxyketones
Disclosed herein is a process for producing a .gamma.-hydroxyketone (2), which comprises asymmetrically hydrogenating a .gamma.-diketone (1) in the presence of a...
US-5,348,980 Enantiomers derived from (S)-2-amino-2-(3,4-dichlorobenzyl)-1-propanol, their use and method of preparation
Enantiomers of (S) configuration of formula (I) ##STR1## in which R is H or methyl, with antiallergic and in particular antihistaminic activity, useful as...
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