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Patent # Description
US-5,177,084 Therapeutic use of substituted benzenes, formulations thereof and novel substituted benzenes
Benzenes, substituted by a non-aromatic, non-fused 1-azabicycle and a substituent of low lipophilicity or a hydrocarbon substituent, their salts and prodrugs are...
US-5,177,068 Pharmaceutical compositions
Iron complexes comprising a ferric cation in combination with at least two different ligands, at least one of which is provided by a compound being: (1)...
US-5,176,917 Transdermal system exhibiting graduated drug release and its use for the local or systemic administration of...
The present invention relates to a transdermal system with graduated drug release and to its use for the local or systemic dermal drug administration in human...
US-5,176,916 Medical adhesives
A medical adhesive comprising a plaster layer containing the following ingredients, characterized in that the ingredient 2 is incorporated in a larger amount...
US-5,176,915 Plaster used as therapeutic system for the administration of active substances to the skin which exhibits a...
The present invention relates to a plaster used as therapeutic system for the administration of active substances to the skin exhibiting an graduated active...
US-5,175,341 Mono ester of dicarboxylic acid and process thereof
Optically active mono-esters of dicarboxylic acid of the formula III: ##STR1## being useful as intermediates for preparing optically active natural products...
US-5,175,285 Polymers derived from polysuccinimide, used as surface coatings for medicinals and foods
A conversion product of polysuccinimide useful as coating material for medicinal preparations and foodstuffs having the structure: ##STR1## wherein A is...
US-5,175,275 Method for preparing powdery crystalline cellulose
The present invention relates to powdery crystalline cellulose having an average particle size ranging from 3 to 30 .mu.m and an average degree of polymerization...
US-5,175,158 Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds
New diazepinones of formula I ##STR1## wherein the substituents are defined herein, which compounds exhibit favorable effects on heart rate and in view of...
US-5,175,082 Method of characterizing genomic DNA
Test samples of genomic DNA may be characterized by the use of polynucleotide probes each of which is specific for an informative genetic locus. Such probes may...
US-5,174,451 Container for dispensing pills, tablets and capsules
A container for dispensing pills, tablets or capsules and comprising a box (10) having hinged lid (16). The box (10) contains a removable compartmented tray (21)...
US-5,173,502 Substituted trifluoropropan-1-yl-imidazole alpha 2-receptor anagonists
A compound selected from those of formula (I): ##STR1## in which R represents straight-chain or branched lower (C.sub.1 -C.sub.6) alkyl, (C.sub.3 -C.sub.8)...
US-5,173,289 Aromatic esters and thioesters, a process for their preparation and their use in human or veterinary medicine...
Aromatic esters and thioesters of the formula ##STR1## are useful in human and veterinary medicine and in cosmetic formulations. In the formula, X...
US-5,171,998 Gamma ray imaging detector
A gamma ray imaging detector is disclosed for use in nuclear medicine applications. The imaging detector includes a single scintillation detector crystal which...
US-5,171,132 Two-valve thin plate micropump
A micropump particularly suited for use in the fields of medicine and analysis includes a thin membrane plate sandwiched between a surface plate and a glass-made...
US-5,170,900 Child resistant closure
A child resistant closure for a medicine bottle wherein an outer cap is freely rotatable on an inner cap. A latch assembly including a slidable latch member and...
US-5,170,380 Medication container holding device indicating usage time
A holding device for medication containers of essentially any size or shape provides the patient with the last time the medicine was taken and includes a housing...
US-5,169,952 Stereoselective production of hydroxyamide compounds from chiral .alpha.-amino epoxides
An efficient process for stereoselective preparation of a medicinally significant hydroxyamide compound of structural formula: ##STR1## comprises the...
US-5,169,856 Piperidinoalkyl derivatives of carboxylic acid amides
The present invention relates to unsaturated carboxylic acid amide derivatives of the formula ##STR1## wherein ring A stands for an optionally substituted...
US-5,169,841 Renin inhibitors
The invention relates to compounds of the formula 1 ##STR1## in which A.sup.1 denotes a radical of the formulae ##STR2## A.sup.2 is absent or...
US-5,169,698 Composite material for use in medicine
A composite material for making supporting dressings or supporting structures for medical use consists of a porous flexible carrier which is impregnated with an...
US-5,169,389 Fluid delivery apparatus
An apparatus for accurately infusing medicinal agents into an ambulatory patient at specific rates over extended periods of time. The apparatus is of a compact,...
US-5,169,385 Safety I. V. drug introducer set
A safety I.V. drug introducer set for use with a I.V. administration set is described for facilitating the injection of drugs into a primary fluid line without...
US-5,168,113 Mercapto-substituted pyridine compounds
A mercapto-substituted pyridine compound having formula (I): ##STR1## where R.sub.1 and R.sub.2 are alkyl groups, and n is 0 or 1, and salts thereof and a...
US-5,166,348 Bornyl and isobornyl esters of carboxylic acids of condensed tetrahydroquinoxalines
Bornyl and isobornyl esters of carboxylic acids of condensed tetrahydroquinoxalines having the general formula ##STR1## where R.sup.1 is CH.sub.3 or C.sub.2...
US-5,166,187 Biomaterials with a base of mixtures of collagen, chitosan and glycosaminoglycans, process for preparing them...
This biomaterial comprises at least a compound consisting of an association of collagen, chitosan acetylated to a degree of acetylation between about 10 and...
US-5,166,157 Naphthyl piperazines useful as 5-HT.sub.1A receptor ligands
Compounds of formula I: ##STR1## in which: N=1-4, R represents hydrogen, halogen, alkyl, hydroxyl or alkoxy, R.sub.1 represents a radical -NHCOR2 (A.sub.1);...
US-5,166,156 Naphthyl piperazines useful as 5-HT.sub.1A receptor ligands
Compounds of formula I: ##STR1## in which: n=1-4, R represents hydrogen, halogen, alkyl, hydroxyl or alkoxy, R.sub.1 represents a radical --NHCOR2...
US-5,166,061 Process for the production of 4-halo-3-hydroxybutyronitrile with Corynebacterium or Microbacterium
A process for the production of a 4-halo-3-hydroxybutyronitrile which comprises reacting a 1,3-dihalo-2-propanol with a dehalogenating enzyme originating from a...
US-5,164,414 Use of N-myristoyl-(S)-phenylalanine for the treatment of diseases involving myristoylation
The invention relates to the use of N-myristoyl-(S)-phenylalanine in the treatment of diseases involving myristoylation such as cancer or AIDS. Medicinal products...
US-5,164,391 Hydantoin derivatives for treating complications of diabetes and circulatory diseases
The invention relates to a hydantoin derivative, salt thereof, process for the preparation thereof, and medicine containing the derivative. The derivative is...
US-5,164,315 Basic protein phospholiphase A2
The present invention relates to a basic protein called phospholipase A2 (PLA2), isolated from the venom of a snake of the family Elapidae, especially of a Naja...
US-5,164,186 Drug-releaser
Disclosed is a drug-releaser comprising a porous body of biocompatibility filled with a medicine. Specifically, such porous body is made of baked calcium...
US-5,162,364 4-aminobutyric acid compounds, compositions, and method of use for treating disorders related to a dysfunction...
A compound of formula (I): ##STR1## in which R, R.sub.1 and R.sub.2 are as defined in the description. Medicinal product, which is useful in treating...
US-5,162,353 Carbacyclins, processes for their preparation, and their use as medicinal agents
The invention relates to carbacyclin derivatives with general formula I: ##STR1## in which Y.sub.1 stands for the radical --CH.sub.2 --X--(CH.sub.2).sub.n ...
US-5,162,324 Naphyl piperazines useful as 5-HT.sub.1A receptor ligands
Compounds of formula I: ##STR1## in which: n=1-4, R represents hydrogen, halogen, alkyl, hydroxyl or alkoxy, R.sub.1 represents a radical --NHCOR2...
US-5,162,323 Inhibition of the withdrawal syndrome
The present invention relates to the use of the derivatives of general formula I ##STR1## in which: n can have the values 1 to 6, and R represents a...
US-5,162,321 1-naphthyl piperazines useful as 5-HT.sub.1A receptor ligands
Compounds of formula I: ##STR1## in which: n=1-4; R represents hydrogen, halogen, alkyl, hydroxyl or alkoxy, R.sub.1 represents a radical --NHCOR2...
US-5,162,113 Oral composition for treating bone disorders
A method and composition for treating bone disease with an herbal medicine is disclosed. The patient is orally treated with a composition including powdered...
US-D330,855 Package for medicine
US-5,160,740 Macromolecular endoplasmic reticulum
The present invention relates to a micromolecular endoplasmic reticulum which comprises a polymer obtained by polymerization of a mixture containing one or more...
US-5,159,581 Medicine reminder and dispenser
A medicine reminder and dispensing apparatus having a plurality of containers arranged in rows and columns in a cabinet, each container including a slidable base...
US-5,159,091 Process for preparing 21-desoxyprednisolone 17-esters
A process for preparing 21-desoxyprednisolone 17-esters of formula (IV) is disclosed. ##STR1## The process comprises reacting a prednisolone...
US-5,158,728 Multi-layer medicinal tablet forming machine and method for using the same
An apparatus for forming a generally cylindrical two-layer, vertically-compressed tablet having a longitudinal axis longer than its diameter is provided in which...
US-5,158,092 Method and azimuthal probe for localizing the emergence point of ventricular tachycardias
Device permitting localization of the emergence point of ventricular tachycardias in cardiological medicine, characterized, in comparison with traditional...
US-5,157,075 Modified melanin
Melanin modified with a polyethylene glycol derivative becomes soluble in water and an organic solvent, and can be applied widely to cosmetics, medicines and dyes.
US-5,157,042 3-oxa-5-fluoro-carbacyclins, their preparation and use as medicinal agents
Carbacyclin derivatives of Formula I ##STR1## wherein R.sub.1 is OR.sub.2, wherein R.sub.2 is hydrogen, alkyl, cycloalkyl, aryl, ##STR2## or a...
US-5,155,116 Medicinal oxazolopyridine compounds
Compounds of general formula (I): ##STR1## in which: R.sub.1 and R.sub.2 each represent a hydrogen atom or, with the nitrogen and oxygen which bear them,...
US-5,154,913 Radioiodinated benzamines method of their use as radioimaging agents
Novel, substituted benzamides in radioiodinated form are useful in radiopharmaceutical compositions in nuclear medicine as imaging agents to detect, visualize,...
US-5,154,912 O.sup.17 isotopic peroxides
The peroxides which include the O.sup.17 isotope, especially the hydrogen peroxides and peroxides and hydroperoxides prepared therefrom, are well adapted as...
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