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Patent # Description
US-8,236,790 Benzothiadiazepine compounds, a process for their preparation and pharmaceutical compositions containing them
Compounds of formula (I): ##STR00001## wherein: R.sub.1 and R.sub.2, which may be the same or different, each represent a hydrogen or halogen atom or an...
US-8,236,488 Method of screening for therapeutic compounds for vascular disorders and hypertension based on URAT1 activity...
It is intended to clarify a transportation system participating in the uric acid uptake in vascular smooth muscle cells (VSMCs) and provide a novel remedy, a...
US-8,236,345 Composition and use
A pharmaceutical composition, comprising a thiazolidinedione, such as Compound (I), metformin hydrochloride and a pharmaceutically acceptable carrier, wherein...
US-8,234,838 Medicine dispensing system and medicine dispensing device
There is provided a medicine dispensing system configured such that a medicine dispensing device includes a sub unit having a function to dispense medicine that...
US-8,232,453 Promoter from sweet potato ran GTPase gene for the high level expression in plant-tissue culture and vector...
Disclosed herein are a promoter (SEQ ID NO.: 1) inducing high level expression of a target gene in plant tissue cultured cells, derived from the sweetpotato...
US-8,232,405 Benzylpiperizine compound
Disclosed is a benzylpiperizine compound represented by formula (1) or a pharmaceutically acceptable salt thereof, which is useful as a medicinal agent such as...
US-8,232,284 Heteroaryloxy quinazoline derivative
Disclosed are compounds of the following formula and their pharmaceutically-acceptable salts, which have an effect of glucokinase activation and are useful in...
US-8,232,279 Pyrazolopyrimidine derivatives having biological activity on serotonin receptor 5-HT2c
The present invention relates to a novel medicinal use of pyrazolopyrimidine compounds having superior effect as serotonin 5-HT.sub.2C receptor ligand thus...
US-8,231,903 Controlled release system
The invention relates to a system for controlled release of medicinally active substances, which comprises sucrose acetate isobutyrate (SAIB) and a further...
US-8,231,871 Perorally administrable antimicrobial composition
The invention relates to medicine and the chemical and pharmaceutical industry, in particular to antibiotic preparative forms. The inventive antimicrobial...
US-8,231,575 Fluid delivery device
A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, oncolytics, hormones, steroids, blood clotting agents,...
US-8,230,619 Footwear orthosis
The present invention is an apparatus and method of orthopedic footwear for post-surgical or diabetic patients or for sanitary use. The footwear has an...
US-8,227,512 Pharmaceutical composition containing daurinol for the prevention and treatment of cancers
The present invention relates to a pharmaceutical composition for the prevention and treatment of cancer comprising daurinol as an active ingredient, more...
US-8,227,507 Ligands that modulate RAR receptors
Novel ligand compounds having the general formula (I): ##STR00001## and pharmaceutical/cosmetic compositions comprised thereof are useful in human and...
US-8,227,492 Sulfoxamine derivatives as factor Xa inhibitors
The present invention relates to novel substituted sulfoximine derivatives of the general formula (I), their tautomeric forms, their stereoisomers, their...
US-8,227,482 Forms of rifaximin and uses thereof
Embodiments relate to Rifaximin polymorphic, salt, and hydrate forms, methods of producing polymorphic forms and to their use in medicinal preparations and to...
US-8,227,463 Amorphous body composed of heterocyclic compound, solid dispersion and pharmaceutical preparation each...
[Problems] The object is to improve the absorbability of a heterocyclic compound including s-triazine and a pyrimidine derivative in vitro. [Means for Solving...
US-8,226,970 Non-woven fiber fabric
In order to provide a non-woven fiber fabric, in particular, in the form of a flat material or as part of a flat material which can be used as a biodegradable...
US-8,226,930 Synthetic MeCP2 sequence for protein substitution therapy
The invention relates to the MeCP2 protein and its use in protein substitution therapy. More specifically, the invention relates to condon-optimized nucleic...
US-8,226,745 Miniature oxygen concentrators and methods
Provided herein are new compact and miniature oxygen concentrator apparatus, as well as methods incorporating use of the apparatus. The apparatus and methods...
US-8,226,631 Drive mechanisms suitable for use in drug delivery devices
The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses...
US-8,226,609 Fluid dispenser with additive sub-system
A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as, antibiotics, analgesics, and like medicinal agents from the device...
US-8,226,608 Medicine dispensing device
Some embodiments of a wearable, disposable medicine dispensing device may include a piston rod that is advanced to dispense medicine from the device. A...
US-8,225,616 Portable medicine cooler having an electronic cooling controller and medicine efficacy indication circuitry and...
A portable medicine cooler and a method of operating the same. In one embodiment, the portable medicine cooler includes: (1) a shell having a grille and further...
US-8,222,283 Method for treating a keratoconjunctival disorder
An object of the present invention is to provide a new medicinal use of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof. ...
US-8,222,220 Nanogenomics for medicine: siRNA engineering
Described herein are materials and methods for the delivery of siRNA and the production of nanoparticles useful for the delivery of siRNA. Methods of treating a...
US-8,221,987 Methods of identifying modulators of bitter taste using hT2R50 receptors
The present invention relates to the discovery of a novel haplotype of the human taste receptor hT2R50 in the T2R taste receptor family that responds to...
US-8,221,770 Vaccine compositions comprising L2 and/or L3 immunotype lipooligosaccharides from LGTB-neisseria meningitidis
The present invention relates to the field of neisserial vaccine compositions, their manufacture, and the use of such compositions in medicine. More...
US-8,221,520 Production of thorium 228 starting from a natural thorium salt
The invention relates to a process for producing .sup.228Th from a natural thorium salt, which comprises in succession: a) the separation of the radium from the...
US-8,221,344 Apparatus for automatic insertion of a solid medicine
An apparatus for insertion of a medicine peg (3) into the skin (4) has a barrel (2) wherein the medicine peg (2) is stored and in which a plunger (8) behind...
US-8,220,224 Medicine supply apparatus
A medicine supply apparatus which comprises, in a case accommodating section 8, a plurality of tablet cases 3 for accommodating medicine and charges or supplies...
US-8,217,084 Medicinal products incorporating bound organosulfur groups
Nutraceutical and dietary supplement formulations for delivering bioavailable thiols to a host, comprising certain organosulfur radicals, such as the allyl...
US-8,217,069 Nitrogenated fused ring derivative, pharmaceutical composition comprising the same, and use of the same for...
[Purpose] The present invention provides compounds useful as agents for the prevention or treatment of a sex hormone-dependent disease or the like. [Solution]...
US-8,217,030 Association of a sinus node if current inhibitor and a beta blocker
Association of a sinus node If current inhibitor and a .beta.-blocker and also pharmaceutical compositions containing it. Medicinal products containing the same...
US-8,215,835 Temperature-stabilized medicinal storage systems
Systems include one or more medicinal storage containers. For example, an integrally thermally sealed medicinal storage container may include one or more...
US-8,215,650 Medical cart, medication module, height adjustment mechanism, and method of medication transport
A medical cart includes a work platform having a work surface and at least one compartment, a base, and a height adjustment mechanism for adjusting the height...
US-8,212,057 Pyrroles having hypolipidemic hypocholesteremic activities, process for their preparation and pharmaceutical...
The present invention relates to novel substituted pyrrole compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their...
US-8,212,037 Process for production of optically active quinuclidinols
A novel ruthenium complex which is a highly efficient catalyst useful for the production of optically active 3-quinuclidinols, and a process for production of...
US-8,211,470 Method for preparing nano-scale or amorphous particle using solid fat as a solvent
The present invention relates to a method for preparing nanoscale or amorphous particles using solid fat as a solvent. According to the present invention,...
US-8,211,085 Therapeutic device for the selective cytoreduction treatment of an obstruction in a natural lumen or passage of...
Therapeutic device intended for the selective cytoreductive treatment of an obstruction in a natural lumen or passage of the human or animal body, said lumen...
US-8,211,059 Fluid dispenser with additive sub-system
A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as, antibiotics, analgesics, and like medicinal agents from the device...
US-8,210,167 Manually operated monodose nasal sprayer
The sprayer device utilizes a friction held piston that fires automatically upon full depression of the firing cap. A user may procure a monodose of medicine by...
US-8,209,943 Distributed medicine supplying device and medicine packaging device
There is provided a distributed medicine supplying device, which allows medicines to be distributed at a time relative to a plurality of prescription data and...
US-8,209,942 Medicine packing device
There is provided a medicine packing device, which prevents a free end of a bottom plate of a tablet dispensing measure from tilting due to its own weight. A...
US-8,207,213 Benzoisoindole derivatives for the treatment of pain
A compound of formula (I) or a pharmaceutically acceptable derivative thereof, ##STR00001## wherein, R.sup.1, R.sup.2, R.sup.3, X and Y are as defined in the...
US-8,207,204 Triazole derivatives as SCD inhibitors
The present invention relates to substituted triazole compounds of the formula (I): ##STR00001## and salts thereof, to pharmaceutical compositions containing...
US-8,207,182 Substituted cyclic urea derivatives and the use thereof as vanilloid receptor 1 modulators
The present invention relates to substituted cyclic urea derivatives corresponding to formula I, to processes for the preparation thereof, to medicinal drugs...
US-8,207,161 Tetrahydro-imidazo[1,5-.alpha.]pyrazine derivatives, preparation process and medicinal use thereof
Tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I), their preparation methods, pharmaceutical compositions containing the derivatives and uses thereof...
US-8,207,159 Use of galanthamine for the treatment of pathological manifestations of the central nervous system based on...
The invention relates to the use of galanthamine, as free base or as acid addition salt, for the treatment of cerebral, central nervous or psychiatric symptoms,...
US-8,206,381 Electrosurgical methods and devices employing phase-controlled radiofrequency energy
This disclosure relates generally to electrosurgical methods and devices. In one embodiment, an electrosurgical device is provided suitable for applying phase...
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