Easy To Use Patents Search & Patent Lawyer Directory

At Patents you can conduct a Patent Search, File a Patent Application, find a Patent Attorney, or search available technology through our Patent Exchange. Patents are available using simple keyword or date criteria. If you are looking to hire a patent attorney, you've come to the right place. Protect your idea and hire a patent lawyer.


Search All Patents:



  This Patent May Be For Sale or Lease. Contact Us

  Is This Your Patent? Claim This Patent Now.



Register or Login To Download This Patent As A PDF




United States Patent Application 20170158735
Kind Code A1
MYASOEDOV; Nikolay Fedorovich ;   et al. June 8, 2017

METHOD FOR PRODUCING A RECOMBINANT PEPTIDE AND RESULTANT PEPTIDE

Abstract

The invention relates to peptides with the following general formula: A-Thr-Lys-Pro-B-C-D-X, where: A--0, Met, Met (O), Thr, Ala, His, Phe, Lys, Gly B--0, Gly, Asp, Trp, Gln, Asn, Tyr, Pro, Arg C--0, Arg, Phe, Tyr, Gly, His, Pro, Lys D--0, Val, Gly, Tyr, Trp, Phe, His X--OH, OCH.sub.3, NH.sub.2, where 0 is no amino acid residue, provided that if A.noteq.0, then B and/or C and/or D.noteq.0, if B.noteq.0, then C and/or D.noteq.0, excluding the peptides Phe-Thr-Lys-Pro-Gly (SEQ ID NO: 1), Thr-Lys-Pro-Pro-Arg (SEQ ID NO: 2), Thr-Lys-Pro-Arg-Gly (SEQ ID NO: 3).


Inventors: MYASOEDOV; Nikolay Fedorovich; (Moscow, RU) ; Andreeva; Lyudmila Alexandrovna; (Moscow, RU) ; Golikov; Dmitriy Viktorovich; (Moscow, RU)
Applicant:
Name City State Country Type

"IVIX" Ltd.

Moscow

RU
Assignee: "IVIX" Ltd.
Moscow
RU

Family ID: 1000002456343
Appl. No.: 15/213039
Filed: July 18, 2016


Related U.S. Patent Documents

Application NumberFiling DatePatent Number
14388080Sep 25, 20149409947
PCT/RU2013/000433May 28, 2013
15213039

Current U.S. Class: 1/1
Current CPC Class: A61K 38/00 20130101; C07K 7/06 20130101
International Class: C07K 7/06 20060101 C07K007/06

Foreign Application Data

DateCodeApplication Number
Mar 28, 2012RU2012111965

Claims



1-2. (canceled)

3. A pharmaceutical composition comprising a peptide of formula: A-Thr-Lys-Pro-B-C-D-X, wherein: A is absent, Met, Met(O), Thr, Ala, His, Phe, Lys; B is absent, Gly, Asp, Trp, Gln, Asn, Tyr, Pro, Arg; C is absent, Arg, Phe, Tyr, Gly, His, Pro; D is absent, Val, Tyr, Trp, Phe, His; X is a carboxy terminal OH, OCH.sub.3, or NH.sub.2 group, provided that (i) when A is present, at least one of B, C, or D is also present, or when B is present, then C and/or D is also present and (ii) the peptide is not a tetrapeptide and is not Thr-Lys-Pro-X (SEQ ID NO: 5), Phe-Thr-Lys-Pro-Gly-X (SEQ ID NO: 1), Thr-Lys-Pro-Pro-Arg-X (SEQ ID NO: 2), Thr-Thr-Lys-Pro-Arg-X (SEQ ID NO: 607), Lys-Thr-Lys-Pro-Arg-X (SEQ ID NO: 772), Thr-Lys-Pro-Gly-Pro-X (SEQ ID NO: 460), Thr-Lys-Pro-Gly-Arg-X (SEQ ID NO: 456), Thr-Lys-Pro-Arg-Tyr (SEQ ID NO: 494), or Thr-Lys-Pro-Arg-Gly-X (SEQ ID NO: 3), wherein said peptide is present in the composition in an amount effective for stimulating sexual or reproductive function.

4. The pharmaceutical composition of claim 3, wherein said peptide is present in the composition in the form of a salt.

5. The pharmaceutical composition of claim 4, wherein said peptide salt is produced by chemical synthesis.

6. The pharmaceutical composition of claim 5, wherein said chemical synthesis includes a step of ion-exchange resin replacing a counter-ion.

7. A method for stimulating sexual or reproductive function in a mammal in need thereof comprising administering to said mammal the pharmaceutical composition of claim 3.

8. The method of claim 7, wherein the mammal has a reproductive or sexual dysfunction.

9. A method for treating a reproductive or sexual dysfunction in a mammal in need of such treatment comprising administering to said mammal the pharmaceutical composition of claim 3.

10. A method for stimulating sexual or reproductive function in a mammal in need thereof comprising administering to said mammal the pharmaceutical composition of claim 4.

11. The method of claim 10, wherein the mammal has a reproductive or sexual dysfunction.

12. A method for treating a reproductive or sexual dysfunction in a mammal in need of such treatment comprising administering to said mammal the pharmaceutical composition of claim 4.

13. A method for stimulating sexual or reproductive function in a mammal in need thereof comprising administering to said mammal a pharmaceutical composition comprising a peptide of formula A-Thr-Lys-Pro-B-C-D-X, wherein: A is absent, Met, Met(O), Thr, Ala, His, Phe, Lys, Gly; B is absent, Gly, Asp, Trp, Gln, Asn, Tyr, Pro, Arg; C is absent, Arg, Phe, Tyr, Gly, His, Pro, Lys; D is absent, Val, Gly, Tyr, Trp, Phe, His; X is a carboxy terminal OH, OCH.sub.3, or NH.sub.2 group, provided that (i) when A is present, at least one of B, C, or D is also present, or when B is present, then C and/or D is also present and (ii) the peptide is not a tetrapeptide.

14. The method of claim 13, wherein said peptide is present in the composition in the form of a salt.

15. The method of claim 13, wherein the mammal has a reproductive or sexual dysfunction.

16. A method for treating a reproductive or sexual dysfunction in a mammal in need of such treatment comprising administering to said mammal a pharmaceutical composition comprising a peptide of formula A-Thr-Lys-Pro-B-C-D-X, wherein: A is absent, Met, Met(O), Thr, Ala, His, Phe, Lys, Gly; B is absent, Gly, Asp, Trp, Gln, Asn, Tyr, Pro, Arg; C is absent, Arg, Phe, Tyr, Gly, His, Pro, Lys; D is absent, Val, Gly, Tyr, Trp, Phe, His; X is a carboxy terminal OH, OCH.sub.3, or NH.sub.2 group, provided that (i) when A is present, at least one of B, C, or D is also present, or when B is present, then C and/or D is also present and (ii) the peptide is not a tetrapeptide.

17. The method of claim 16, wherein said peptide is present in the composition in the form of a salt.
Description



CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application is a U.S. National Phase Application under 35 U.S.C. .sctn.371 of International Patent Application No. PCT/RU2013/000433 filed May 28, 2013, which claims priority to Russian Patent Application No. 2012111965 filed Mar. 28, 2012. The International Application was published on Oct. 10, 2013, as International Publication No. WO 2013/151467 under PCT Article 21(2). The entire contents of these applications are hereby incorporated by reference.

SEQUENCE LISTING

[0002] The instant application contains a Sequence Listing which has been submitted electronically in ASCII format and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Dec. 8, 2014, is named 246273.000002_SL.txt and is 559,963 bytes in size.

FIELD OF INVENTION

[0003] The invention relates to the field of biochemistry and concerns of recombinant method for production of peptides and the resulting peptides. In particular, the invention relates to peptides with the following general formula:

A-Thr-Lys-Pro-B-C-D-X, where:

A--0, Met, Met (O), Thr, Ala, His, Phe, Lys, Gly

B--0, Gly, Asp, Trp, Gln, Asn, Tyr, Pro, Arg

C--0, Arg, Phe, Tyr, Gly, His, Pro, Lys

D--0, Val, Gly, Tyr, Trp, Phe, His

[0004] X--OH, OCH.sub.3, NH.sub.2, where 0 is no amino acid residue, provided that if A.noteq.0, then B and/or C and/or D.noteq.0, if B.noteq.0, then C and/or D.noteq.0, excluding the peptides Phe-Thr-Lys-Pro-Gly (SEQ ID NO: 1), Thr-Lys-Pro-Pro-Arg (SEQ ID NO: 2), Thr-Lys-Pro-Arg-Gly (SEQ ID NO: 3).

BACKGROUND OF THE INVENTION

[0005] It is known that small peptides exhibit extremely high activity, stimulating self-healing in the organs where a disturbance occurred. As it is commonly known, smaller peptides were initially derived from animal tissues, and later they learned to produce them in laboratory conditions. Medicinal products containing peptides are capable of restoring damaged body cells, returning lost functions to the affected organ, and rejuvenating it. Medicinal products containing peptides were developed more than three decades ago; since that time, hundreds of experiments have been performed, which proved the efficacy of peptides in treatment and prevention of diseases of various body systems, as well as individual organ- and all-body rejuvenation.

[0006] In the body, peptides serve as information messengers: they transfer information from one cell to another, so that everything could be done well and on time. If one cell functions properly, then the corresponding organ operates well. If a malfunction occurs, it affects the whole organ, leading to a disease. Clearly, it is possible to treat the disease by introducing missing substances into the body, but this approach would completely `spoil` the cell, and it would stop functioning properly. Therefore, it is necessary to send peptide messengers to the cell, which will make it function, so that the body would heal itself. Each organ has a supply of reserve stem cells. If this supply is spent evenly, one lives to the age of 100-110. Peptides are the same for all mammals. Therefore, if a calf peptide is introduced to a human, their body will take it as native molecule. The main problem was to find how to isolate peptides from animal organs. This technology was invented by Prof. Vladimir Morozov and Prof. Vyacheslav Havinson in Military Medical Academy as early as in 1971. Medicinal products were developed, and then, based on them, dietary supplements were made, because dietary supplements are easy to use. In their studies of aging processes and methods to influence it, employees of St. Petersburg Institute of Gerontology concluded that introduction of peptides into the diet of experimental group of mice increased their life expectancy by 30-38%. Later, studies of peptides were performed on the elderly in Kiev Institute of Gerontology and in St. Petersburg. This showed almost 2-fold reduction of mortality rate, indicating high geroprotective activity of peptides. Long-term study and use of peptide medicinal products showed their high efficacy in patients of different age groups; however, particular efficacy was observed in elderly (over 50 years old). Absolute advantage of peptide bioregulators is absence of any adverse reactions. Within 26 years, more than 15 mln. people with various pathologies received such products. Their efficacy averaged to 75-95%. Peptide deficit, developing with age and pathologic changes, significantly accelerates tissue wear and body aging. The fact is that an adequate functioning of cells and tissues requires adequate amounts of peptides, which, in turn, support optimal gene operation. Peptides, functioning in cells specific for them, are synthesized there. Therefore, in pathological changes, as well as with age, cell functioning is disrupted; hence, peptide reproduction is affected as well. Consequently, cell function is affected secondarily. Thus, degeneration of tissues progresses, which eventually is manifested clinically. So, application of small peptides is one of the major innovations in medicine and can significantly slow down the rate of aging by stimulating cell proliferation and tissue regeneration, as well as enhancing cell life span. Another important advantage of peptides is their antitumor action. Currently, the use of peptides is the best and uncompromising solution in revitalization (body rejuvenation) and cancer prevention, because it allows to rejuvenate cells and tissues not only by regulation and synchronization of all cyclic processes, but also by increasing the capacity of cell division without atypia (atypia is an incorrect cell structure, or abnormality).

[0007] Of course, at the present stage of art, small peptide production from animal tissues is impractical, since this method is very expensive, not to mention the humanity of the production process.

[0008] A modern and advanced production method comprises using recombinant microorganisms. Most convenient microorganism is E. coli. Commercial strains of E. coli, suitable for use in laboratory conditions, such as E. coli K12, E. coli 0104, are known in the prior art. These and similar known E. coli strains can be used to obtain strains producing small peptides claimed. A nucleic acid, encoding the corresponding target small peptide, can be integrated in any known strain, suitable for use in the laboratory conditions. Vectors, such as bacterial plasmids, viruses, virions, hybrid vectors containing phage DNA, and plasmids, are used to insert DNA into a host cell. These vectors include, for example, cosmids and phasmids.

[0009] Furthermore, it is possible to produce peptides by conventional chemical synthesis.

[0010] Proposed peptides solve the problem of expanding the range of tools for stimulation of reproductive and sexual function and treatment of reproductive and sexual dysfunction, which remains relevant now. Currently, pathogenetic treatment of such pathologies is performed using psychotherapy, antidepressants, anxiolytics, adaptogens, as well as vitamins, common plant-based stimulants, and diet supplements. Such treatment is long, inefficient and accompanied by many side effects.

[0011] One of the most effective classes of physiologically active substances, suitable for production of stimulants of reproductive and sexual function, is peptides, which, as endogenous substances, have virtually no negative side effects.

[0012] Our own research showed that heptapeptide Selank with the general formula of Thr-Lys-Pro-Arg-Pro-Gly-Pro (SEQ ID NO: 2680), a synthetic analog of the endogenously produced peptide Tuftsin, can be used as a tool for prevention and treatment of reproductive and sexual dysfunction (Patent of Russian Federation No. 2404793). However, the synthesis of heptapeptide Selank is multistage, which greatly increases the cost of medicinal products based on it; moreover, it is exposed to intense proteolysis in the body, which reduces its stimulating effect on prevention and treatment of reproductive and sexual dysfunction.

DISCLOSURE OF INVENTION

[0013] The aim of the invention is to expand the range of tools with reproductive- and sexual-function stimulating activity.

[0014] Technical result, achieved when implementing the present invention, is an increase in efficacy of prevention and treatment of reproductive and sexual dysfunction, reduction in duration of course therapy, and cost reduction of medications, where peptides with the following general formula are proposed as a medicinal product:

A-Thr-Lys-Pro-B-C-D-X, where:

A--0, Met, Met (O), Thr, Ala, His, Phe, Lys, Gly

B--0, Gly, Asp, Trp, Gln, Asn, Tyr, Pro, Arg

C--0, Arg, Phe, Tyr, Gly, His, Pro, Lys

D--0, Val, Gly, Tyr, Trp, Phe, His

[0015] X--OH, OCH.sub.3, NH.sub.2, where 0 means no amino acid residue.

[0016] Provided that if A.noteq.0, then B and/or C and/or D.noteq.0; if B.noteq.0, then C and/or D.noteq.0, excluding peptides Phe-Thr-Lys-Pro-Gly (SEQ ID NO: 1), Thr-Lys-Pro-Pro-Arg (SEQ ID NO: 2), Thr-Lys-Pro-Arg-Gly (SEQ ID NO: 3).

[0017] Selection of amino acid residues at positions A, B, C, D, and X is based on a bioinformatic analysis of amino acid residue frequency at corresponding positions of N-terminal and C-terminal amino acid residues in the database [EROP-Moscow (erop.inbi.ras.ru/) Zamyatin A. A. EROP-Moscow: Specialized data bank for endogenous regulatory oligopeptides, Protein Sequence and Data Analysis, 4(1), 49-52, 1991; Zamyatnin A. A. et al., The EROP-Moscow oligopeptide database. Nucleic Asids Research, 34(Database issue), D261-D266, 2006]. Selection of these amino acid residues was performed based on the criterion of greater than 50% incidence of an amino acid residue at that position. This sample of amino acid residues was experimentally confirmed by synthesis of individual peptides and their test for stimulation of reproductive- and sexual-function activity in models in vivo. Pharmacophore position in a peptide is determined experimentally. It is known that any peptide is exposed to peptidases and breaks down into specific fragments. For this purpose, following Selank heptapeptide fragments were synthesized: Thr-Lys (SEQ ID NO: 2678), Thr-Lys-Pro (SEQ ID NO: 5), Pro-Gly-Pro (SEQ ID NO: 2677), Arg-Pro-Gly-Pro (SEQ ID NO: 2676), Pro-Arg-Pro-Gly-Pro (SEQ ID NO: 2675), and their activity was studied. Results are provided in Table 4. In this analysis, pharmacophore was determined: it is Thr-Lys-Pro (SEQ ID NO: 5). It was shown that attachment of individual experimentally identified amino acid residues to the C-terminus maintained the peptide's activity (stimulating reproductive and sexual function) provided that the number of amino acid residues in the peptide is 3 or more than 4, as shown by studies (Table 5, Example 10). Tetrapeptides do not have reproductive and sexual-function stimulating activity. Mentioned technical result is achieved by directed synthesis of various peptides with the general formula A-Thr-Lys-Pro-B-C-D-X (except tetrapeptides) and by using these peptides as a stimulant of reproductive and sexual function for prevention and treatment of reproductive and sexual dysfunction.

[0018] Our own research showed that synthesized peptides, i.e. Thr-Lys-Pro tripeptide (SEQ ID NO: 5), Thr-Lys-Pro-Arg-Pro pentapeptide (SEQ ID NO: 6), and Thr-Lys-Pro-Arg-Pro-Phe hexapeptide (SEQ ID NO: 7), corresponding to the general formula A-Thr-Lys-Pro-B-C-D-X, can be recommended as stimulants of reproductive and sexual function.

[0019] All peptides with the general formula A-Thr-Lys-Pro-B-C-D-X (except tetrapeptides), recommended as stimulants of reproductive and sexual function, have a common pattern, i.e. Thr-Lys-Pro tripeptide molecule is present in their molecular structure.

[0020] Thr-Lys-Pro-Arg-Pro-Gly-Pro (SEQ ID NO: 2680) heptapeptide (Selank) was used as a control. Results of conducted studies showed that peptides with the general formula A-Thr-Lys-Pro-B-C-D-X (except tetrapeptides) have reproductive- and sexual-function stimulating activity and can be used as medicinal products for prevention and treatment of reproductive and sexual dysfunction.

[0021] Some peptides of the general formula A-Thr-Lys-Pro-B-C-D-X are shown in Table 1.

TABLE-US-00001 TABLE 1 SEQ ID X-OH X-OCH.sub.3 X-NH.sub.2 NO Thr-Lys-Pro Thr-Lys-Pro Thr-Lys-Pro 5 Thr-Lys-Pro-Arg-His Thr-Lys-Pro-Arg-His Thr-Lys-Pro-Arg-His 8 Thr-Lys-Pro-Phe-His Thr-Lys-Pro-Phe-His Thr-Lys-Pro-Phe-His 9 Thr-Lys-Pro-Tyr-His Thr-Lys-Pro-Tyr-His Thr-Lys-Pro-Tyr-His 10 Thr-Lys-Pro-Gly-His Thr-Lys-Pro-Gly-His Thr-Lys-Pro-Gly-His 11 Thr-Lys-Pro-His-His Thr-Lys-Pro-His-His Thr-Lys-Pro-His-His 12 Thr-Lys-Pro-Lys-His Thr-Lys-Pro-Lys-His Thr-Lys-Pro-Lys-His 13 Thr-Lys-Pro-Gly-His Thr-Lys-Pro-Gly-His Thr-Lys-Pro-Gly-His 14 Thr-Lys-Pro-Gly-Arg-His Thr-Lys-Pro-Gly-Arg-His Thr-Lys-Pro-Gly-Arg-His 15 Thr-Lys-Pro-Gly-Phe-His Thr-Lys-Pro-Gly-Phe-His Thr-Lys-Pro-Gly-Phe-His 16 Thr-Lys-Pro-Gly-Tyr-His Thr-Lys-Pro-Gly-Tyr-His Thr-Lys-Pro-Gly-Tyr-His 17 Thr-Lys-Pro-Gly-His-His Thr-Lys-Pro-Gly-His-His Thr-Lys-Pro-Gly-His-His 18 Thr-Lys-Pro-Gly-Pro-His Thr-Lys-Pro-Gly-Pro-His Thr-Lys-Pro-Gly-Pro-His 19 Thr-Lys-Pro-Gly-Lys-His Thr-Lys-Pro-Gly-Lys-His Thr-Lys-Pro-Gly-Lys-His 20 Thr-Lys-Pro-Asp-His Thr-Lys-Pro-Asp-His Thr-Lys-Pro-Asp-His 21 Thr-Lys-Pro-Asp-Arg-His Thr-Lys-Pro-Asp-Arg-His Thr-Lys-Pro-Asp-Arg-His 22 Thr-Lys-Pro-Asp-Phe-His Thr-Lys-Pro-Asp-Phe-His Thr-Lys-Pro-Asp-Phe-His 23 Thr-Lys-Pro-Asp-Tyr-His Thr-Lys-Pro-Asp-Tyr-His Thr-Lys-Pro-Asp-Tyr-His 24 Thr-Lys-Pro-Asp-His-His Thr-Lys-Pro-Asp-His-His Thr-Lys-Pro-Asp-His-His 25 Thr-Lys-Pro-Asp-Pro-His Thr-Lys-Pro-Asp-Pro-His Thr-Lys-Pro-Asp-Pro-His 26 Thr-Lys-Pro-Asp-Lys-His Thr-Lys-Pro-Asp-Lys-His Thr-Lys-Pro-Asp-Lys-His 27 Thr-Lys-Pro-Trp-His Thr-Lys-Pro-Trp-His Thr-Lys-Pro-Trp-His 28 Thr-Lys-Pro-Trp-Arg-His Thr-Lys-Pro-Trp-Arg-His Thr-Lys-Pro-Trp-Arg-His 29 Thr-Lys-Pro-Trp-Phe-His Thr-Lys-Pro-Trp-Phe-His Thr-Lys-Pro-Trp-Phe-His 30 Thr-Lys-Pro-Trp-Tyr-His Thr-Lys-Pro-Trp-Tyr-His Thr-Lys-Pro-Trp-Tyr-His 31 Thr-Lys-Pro-Trp-His-His Thr-Lys-Pro-Trp-His-His Thr-Lys-Pro-Trp-His-His 32 Thr-Lys-Pro-Trp-Pro-His Thr-Lys-Pro-Trp-Pro-His Thr-Lys-Pro-Trp-Pro-His 33 Thr-Lys-Pro-Trp-Lys-His Thr-Lys-Pro-Trp-Lys-His Thr-Lys-Pro-Trp-Lys-His 34 Thr-Lys-Pro-Gln-His Thr-Lys-Pro-Gln-His Thr-Lys-Pro-Gln-His 35 Thr-Lys-Pro-Gln-Arg-His Thr-Lys-Pro-Gln-Arg-His Thr-Lys-Pro-Gln-Arg-His 36 Thr-Lys-Pro-Gln-Phe-His Thr-Lys-Pro-Gln-Phe-His Thr-Lys-Pro-Gln-Phe-His 37 Thr-Lys-Pro-Gln-Tyr-His Thr-Lys-Pro-Gln-Tyr-His Thr-Lys-Pro-Gln-Tyr-His 38 Thr-Lys-Pro-Gln-His-His Thr-Lys-Pro-Gln-His-His Thr-Lys-Pro-Gln-His-His 39 Thr-Lys-Pro-Gln-Pro-His Thr-Lys-Pro-Gln-Pro-His Thr-Lys-Pro-Gln-Pro-His 40 Thr-Lys-Pro-Gln-Lys-His Thr-Lys-Pro-Gln-Lys-His Thr-Lys-Pro-Gln-Lys-His 41 Thr-Lys-Pro-Asn-His Thr-Lys-Pro-Asn-His Thr-Lys-Pro-Asn-His 42 Thr-Lys-Pro-Asn-Arg-His Thr-Lys-Pro-Asn-Arg-His Thr-Lys-Pro-Asn-Arg-His 43 Thr-Lys-Pro-Asn-Phe-His Thr-Lys-Pro-Asn-Phe-His Thr-Lys-Pro-Asn-Phe-His 44 Thr-Lys-Pro-Asn-Tyr-His Thr-Lys-Pro-Asn-Tyr-His Thr-Lys-Pro-Asn-Tyr-His 45 Thr-Lys-Pro-Asn-His-His Thr-Lys-Pro-Asn-His-His Thr-Lys-Pro-Asn-His-His 46 Thr-Lys-Pro-Asn-Pro-His Thr-Lys-Pro-Asn-Pro-His Thr-Lys-Pro-Asn-Pro-His 47 Thr-Lys-Pro-Asn-Lys-His Thr-Lys-Pro-Asn-Lys-His Thr-Lys-Pro-Asn-Lys-His 48 Thr-Lys-Pro-Tyr-His Thr-Lys-Pro-Tyr-His Thr-Lys-Pro-Tyr-His 49 Thr-Lys-Pro-Tyr-Arg-His Thr-Lys-Pro-Tyr-Arg-His Thr-Lys-Pro-Tyr-Arg-His 50 Thr-Lys-Pro-Tyr-Phe-His Thr-Lys-Pro-Tyr-Phe-His Thr-Lys-Pro-Tyr-Phe-His 51 Thr-Lys-Pro-Tyr-Tyr-His Thr-Lys-Pro-Tyr-Tyr-His Thr-Lys-Pro-Tyr-Tyr-His 52 Thr-Lys-Pro-Tyr-His-His Thr-Lys-Pro-Tyr-His-His Thr-Lys-Pro-Tyr-His-His 53 Thr-Lys-Pro-Tyr-Pro-His Thr-Lys-Pro-Tyr-Pro-His Thr-Lys-Pro-Tyr-Pro-His 54 Thr-Lys-Pro-Tyr-Lys-His Thr-Lys-Pro-Tyr-Lys-His Thr-Lys-Pro-Tyr-Lys-His 55 Thr-Lys-Pro-Arg-His Thr-Lys-Pro-Arg-His Thr-Lys-Pro-Arg-His 56 Thr-Lys-Pro-Arg-Arg-His Thr-Lys-Pro-Arg-Arg-His Thr-Lys-Pro-Arg-Arg-His 57 Thr-Lys-Pro-Arg-Phe-His Thr-Lys-Pro-Arg-Phe-His Thr-Lys-Pro-Arg-Phe-His 58 Thr-Lys-Pro-Arg-Tyr-His Thr-Lys-Pro-Arg-Tyr-His Thr-Lys-Pro-Arg-Tyr-His 59 Thr-Lys-Pro-Arg-His-His Thr-Lys-Pro-Arg-His-His Thr-Lys-Pro-Arg-His-His 60 Thr-Lys-Pro-Arg-Pro-His Thr-Lys-Pro-Arg-Pro-His Thr-Lys-Pro-Arg-Pro-His 61 Thr-Lys-Pro-Arg-Lys-His Thr-Lys-Pro-Arg-Lys-His Thr-Lys-Pro-Arg-Lys-His 62 Met-Thr-Lys-Pro-His Met-Thr-Lys-Pro-His Met-Thr-Lys-Pro-His 63 Met-Thr-Lys-Pro-Arg-His Met-Thr-Lys-Pro-Arg-His Met-Thr-Lys-Pro-Arg-His 64 Met-Thr-Lys-Pro-Phe-His Met-Thr-Lys-Pro-Phe-His Met-Thr-Lys-Pro-Phe-His 65 Met-Thr-Lys-Pro-Tyr-His Met-Thr-Lys-Pro-Tyr-His Met-Thr-Lys-Pro-Tyr-His 66 Met-Thr-Lys-Pro-Gly-His Met-Thr-Lys-Pro-Gly-His Met-Thr-Lys-Pro-Gly-His 67 Met-Thr-Lys-Pro-His-His Met-Thr-Lys-Pro-His-His Met-Thr-Lys-Pro-His-His 68 Met-Thr-Lys-Pro-Lys-His Met-Thr-Lys-Pro-Lys-His Met-Thr-Lys-Pro-Lys-His 69 Met-Thr-Lys-Pro-Gly-His Met-Thr-Lys-Pro-Gly-His Met-Thr-Lys-Pro-Gly-His 70 Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Arg- Met-Thr-Lys-Pro-Gly- 71 Arg-His His Arg-His Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Phe- Met-Thr-Lys-Pro-Gly- 72 Phe-His His Phe-His Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Tyr- Met-Thr-Lys-Pro-Gly- 73 Tyr-His His Tyr-His Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-His- Met-Thr-Lys-Pro-Gly-His- 74 His-His His His Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Pro- Met-Thr-Lys-Pro-Gly-Pro- 75 Pro-His His His Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Lys- Met-Thr-Lys-Pro-Gly- 76 Lys-His His Lys-His Met-Thr-Lys-Pro-Asp-His Met-Thr-Lys-Pro-Asp-His Met-Thr-Lys-Pro-Asp-His 77 Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Arg- Met-Thr-Lys-Pro-Asp- 78 Arg-His His Arg-His Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Phe- Met-Thr-Lys-Pro-Asp- 79 Phe-His His Phe-His Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Tyr- Met-Thr-Lys-Pro-Asp- 80 Tyr-His His Tyr-His Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-His- Met-Thr-Lys-Pro-Asp- 81 His-His His His-His Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Pro- Met-Thr-Lys-Pro-Asp- 82 Pro-His His Pro-His Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Lys- Met-Thr-Lys-Pro-Asp- 83 Lys-His His Lys-His Met-Thr-Lys-Pro-Trp-His Met-Thr-Lys-Pro-Trp-His Met-Thr-Lys-Pro-Trp-His 84 Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Arg- Met-Thr-Lys-Pro-Trp- 85 Arg-His His Arg-His Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Phe- Met-Thr-Lys-Pro-Trp- 86 Phe-His His Phe-His Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Tyr- Met-Thr-Lys-Pro-Trp-Tyr- 87 Tyr-His His His Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-His- Met-Thr-Lys-Pro-Trp-His- 88 His-His His His Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Pro- Met-Thr-Lys-Pro-Trp-Pro- 89 Pro-His His His Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Lys- Met-Thr-Lys-Pro-Trp- 90 Lys-His His Lys-His Met-Thr-Lys-Pro-Gln-His Met-Thr-Lys-Pro-Gln-His Met-Thr-Lys-Pro-Gln-His 91 Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Arg- Met-Thr-Lys-Pro-Gln- 92 Arg-His His Arg-His Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Phe- Met-Thr-Lys-Pro-Gln- 93

Phe-His His Phe-His Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Tyr- Met-Thr-Lys-Pro-Gln- 94 Tyr-His His Tyr-His Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-His- Met-Thr-Lys-Pro-Gln-His- 95 His-His His His Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Pro- Met-Thr-Lys-Pro-Gln-Pro- 96 Pro-His His His Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Lys- Met-Thr-Lys-Pro-Gln- 97 Lys-His His Lys-His Met-Thr-Lys-Pro-Asn-His Met-Thr-Lys-Pro-Asn-His Met-Thr-Lys-Pro-Asn-His 98 Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Arg- Met-Thr-Lys-Pro-Asn- 99 Arg-His His Arg-His Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Phe- Met-Thr-Lys-Pro-Asn- 100 Phe-His His Phe-His Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Tyr- Met-Thr-Lys-Pro-Asn- 101 Tyr-His His Tyr-His Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-His- Met-Thr-Lys-Pro-Asn- 102 His-His His His-His Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Pro- Met-Thr-Lys-Pro-Asn- 103 Pro-His His Pro-His Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Lys- Met-Thr-Lys-Pro-Asn- 104 Lys-His His Lys-His Met-Thr-Lys-Pro-Tyr-His Met-Thr-Lys-Pro-Tyr-His Met-Thr-Lys-Pro-Tyr-His 105 Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Arg- Met-Thr-Lys-Pro-Tyr- 106 Arg-His His Arg-His Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Phe- Met-Thr-Lys-Pro-Tyr- 107 Phe-His His Phe-His Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- 108 Tyr-His His His Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-His- Met-Thr-Lys-Pro-Tyr-His- 109 His-His His His Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Pro- Met-Thr-Lys-Pro-Tyr-Pro- 110 Pro-His His His Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Lys- Met-Thr-Lys-Pro-Tyr- 111 Lys-His His Lys-His Met-Thr-Lys-Pro-Arg-His Met-Thr-Lys-Pro-Arg-His Met-Thr-Lys-Pro-Arg-His 112 Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Arg- Met-Thr-Lys-Pro-Arg- 113 Arg-His His Arg-His Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Phe- Met-Thr-Lys-Pro-Arg- 114 Phe-His His Phe-His Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Tyr- Met-Thr-Lys-Pro-Arg- 115 Tyr-His His Tyr-His Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-His- Met-Thr-Lys-Pro-Arg- 116 His-His His His-His Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Pro- Met-Thr-Lys-Pro-Arg- 117 Pro-His His Pro-His Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Lys- Met-Thr-Lys-Pro-Arg- 118 Lys-His His Lys-His Met(O)-Thr-Lys-Pro-His Met(O)-Thr-Lys-Pro-His Met(O)-Thr-Lys-Pro-His 119 Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 120 His His His Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- 121 His His His Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 122 His His His Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 123 His His His Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- 124 His His His Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- 125 His His His Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 126 His His His Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 127 Arg-His Arg-His Arg-His Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 128 Phe-His Phe-His Phe-His Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 129 Tyr-His Tyr-His Tyr-His Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 130 His-His His-His His-His Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 131 Pro-His Pro-His Pro-His Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 132 Lys-His Lys-His Lys-His Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 133 His His His Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 134 Arg-His Arg-His Arg-His Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 135 Phe-His Phe-His Phe-His Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 136 Tyr-His Tyr-His Tyr-His Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 137 His-His His-His His-His Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 138 Pro-His Pro-His Pro-His Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 139 Lys-His Lys-His Lys-His Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 140 His His His Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 141 Arg-His Arg-His Arg-His Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 142 Phe-His Phe-His Phe-His Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 143 Tyr-His Tyr-His Tyr-His Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 144 His-His His-His His-His Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 145 Pro-His Pro-His Pro-His Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 146 Lys-His Lys-His Lys-His Met(O)-Thr-Lys-Pro-G1n- Met(O)-Thr-Lys-Pro-G1n- Met(O)-Thr-Lys-Pro-G1n- 147 His His His Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 148 Arg-His Arg-His Arg-His Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 149 Phe-His Phe-His Phe-His Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 150 Tyr-His Tyr-His Tyr-His Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 151 His-His His-His His-His Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 152 Pro-His Pro-His Pro-His Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 153 Lys-His Lys-His Lys-His Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 154 His His His Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 155 Arg-His Arg-His Arg-His Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 156 Phe-His Phe-His Phe-His Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 157 Tyr-His Tyr-His Tyr-His Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 158 His-His His-His His-His Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 159 Pro-His Pro-His Pro-His Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 160 Lys-His Lys-His Lys-His Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 161 His His His Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr-

162 Arg-His Arg-His Arg-His Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 163 Phe-His Phe-His Phe-His Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 164 Tyr-His Tyr-His Tyr-His Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 165 His-His His-His His-His Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 166 Pro-His Pro-His Pro-His Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 167 Lys-His Lys-His Lys-His Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 168 His His His Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 169 Arg-His Arg-His Arg-His Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 170 Phe-His Phe-His Phe-His Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 171 Tyr-His Tyr-His Tyr-His Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 172 His-His His-His His-His Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 173 Pro-His Pro-His Pro-His Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 174 Lys-His Lys-His Lys-His Thr-Thr-Lys-Pro-His Thr-Thr-Lys-Pro-His Thr-Thr-Lys-Pro-His 175 Thr-Thr-Lys-Pro-Arg-His Thr-Thr-Lys-Pro-Arg-His Thr-Thr-Lys-Pro-Arg-His 176 Thr-Thr-Lys-Pro-Phe-His Thr-Thr-Lys-Pro-Phe-His Thr-Thr-Lys-Pro-Phe-His 177 Thr-Thr-Lys-Pro-Tyr-His Thr-Thr-Lys-Pro-Tyr-His Thr-Thr-Lys-Pro-Tyr-His 178 Thr-Thr-Lys-Pro-Gly-His Thr-Thr-Lys-Pro-Gly-His Thr-Thr-Lys-Pro-Gly-His 179 Thr-Thr-Lys-Pro-His-His Thr-Thr-Lys-Pro-His-His Thr-Thr-Lys-Pro-His-His 180 Thr-Thr-Lys-Pro-Lys-His Thr-Thr-Lys-Pro-Lys-His Thr-Thr-Lys-Pro-Lys-His 181 Thr-Thr-Lys-Pro-Gly-His Thr-Thr-Lys-Pro-Gly-His Thr-Thr-Lys-Pro-Gly-His 182 Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Arg- Thr-Thr-Lys-Pro-Gly-Arg- 183 Arg-His His His Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Phe- Thr-Thr-Lys-Pro-Gly-Phe- 184 Phe-His His His Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Tyr- Thr-Thr-Lys-Pro-Gly-Tyr- 185 Tyr-His His His Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- 186 His His His Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- 187 His His His Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Lys- Thr-Thr-Lys-Pro-Gly-Lys- 188 Lys-His His His Thr-Thr-Lys-Pro-Asp-His Thr-Thr-Lys-Pro-Asp-His Thr-Thr-Lys-Pro-Asp-His 189 Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Arg- Thr-Thr-Lys-Pro-Asp- 190 Arg-His His Arg-His Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Phe- Thr-Thr-Lys-Pro-Asp- 191 Phe-His His Phe-His Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Tyr- Thr-Thr-Lys-Pro-Asp-Tyr- 192 Tyr-His His His Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-His- Thr-Thr-Lys-Pro-Asp-His- 193 His-His His His Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Pro- Thr-Thr-Lys-Pro-Asp-Pro- 194 Pro-His His His Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Lys- Thr-Thr-Lys-Pro-Asp- 195 Lys-His His Lys-His Thr-Thr-Lys-Pro-Trp-His Thr-Thr-Lys-Pro-Trp-His Thr-Thr-Lys-Pro-Trp-His 196 Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Arg- Thr-Thr-Lys-Pro-Trp-Arg- 197 Arg-His His His Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Phe- Thr-Thr-Lys-Pro-Trp-Phe- 198 Phe-His His His Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- 199 His His His Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- 200 His His His Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- 201 His His His Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Lys- Thr-Thr-Lys-Pro-Trp-Lys- 202 Lys-His His His Thr-Thr-Lys-Pro-Gln-His Thr-Thr-Lys-Pro-Gln-His Thr-Thr-Lys-Pro-Gln-His 203 Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Arg- Thr-Thr-Lys-Pro-Gln-Arg- 204 Arg-His His His Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Phe- Thr-Thr-Lys-Pro-Gln-Phe- 205 Phe-His His His Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Tyr- Thr-Thr-Lys-Pro-Gln-Tyr- 206 Tyr-His His His Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- 207 His His His Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- 208 His His His Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Lys- Thr-Thr-Lys-Pro-Gln-Lys- 209 Lys-His His His Thr-Thr-Lys-Pro-Asn-His Thr-Thr-Lys-Pro-Asn-His Thr-Thr-Lys-Pro-Asn-His 210 Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Arg- Thr-Thr-Lys-Pro-Asn- 211 Arg-His His Arg-His Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Phe- Thr-Thr-Lys-Pro-Asn- 212 Phe-His His Phe-His Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Tyr- Thr-Thr-Lys-Pro-Asn-Tyr- 213 Tyr-His His His Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-His- Thr-Thr-Lys-Pro-Asn-His- 214 His-His His His Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Pro- Thr-Thr-Lys-Pro-Asn-Pro- 215 Pro-His His His Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Lys- Thr-Thr-Lys-Pro-Asn- 216 Lys-His His Lys-His Thr-Thr-Lys-Pro-Tyr-His Thr-Thr-Lys-Pro-Tyr-His Thr-Thr-Lys-Pro-Tyr-His 217 Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Arg- Thr-Thr-Lys-Pro-Tyr-Arg- 218 Arg-His His His Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Phe- Thr-Thr-Lys-Pro-Tyr-Phe- 219 Phe-His His His Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- 220 His His His Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- 221 His His His Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- 222 His His His Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Lys- Thr-Thr-Lys-Pro-Tyr-Lys- 223 Lys-His His His Thr-Thr-Lys-Pro-Arg-His Thr-Thr-Lys-Pro-Arg-His Thr-Thr-Lys-Pro-Arg-His 224 Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Arg- Thr-Thr-Lys-Pro-Arg- 225 Arg-His His Arg-His Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Phe- Thr-Thr-Lys-Pro-Arg-Phe- 226 Phe-His His His Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Tyr- Thr-Thr-Lys-Pro-Arg-Tyr- 227 Tyr-His His His Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-His- Thr-Thr-Lys-Pro-Arg-His- 228 His-His His His Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Pro- Thr-Thr-Lys-Pro-Arg-Pro- 229 Pro-His His His Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Lys- Thr-Thr-Lys-Pro-Arg-Lys- 230

Lys-His His His Ala-Thr-Lys-Pro-His Ala-Thr-Lys-Pro-His Ala-Thr-Lys-Pro-His 231 Ala-Thr-Lys-Pro-Arg-His Ala-Thr-Lys-Pro-Arg-His Ala-Thr-Lys-Pro-Arg-His 232 Ala-Thr-Lys-Pro-Phe-His Ala-Thr-Lys-Pro-Phe-His Ala-Thr-Lys-Pro-Phe-His 233 Ala-Thr-Lys-Pro-Tyr-His Ala-Thr-Lys-Pro-Tyr-His Ala-Thr-Lys-Pro-Tyr-His 234 Ala-Thr-Lys-Pro-Gly-His Ala-Thr-Lys-Pro-Gly-His Ala-Thr-Lys-Pro-Gly-His 235 Ala-Thr-Lys-Pro-His-His Ala-Thr-Lys-Pro-His-His Ala-Thr-Lys-Pro-His-His 236 Ala-Thr-Lys-Pro-Lys-His Ala-Thr-Lys-Pro-Lys-His Ala-Thr-Lys-Pro-Lys-His 237 Ala-Thr-Lys-Pro-Gly-His Ala-Thr-Lys-Pro-Gly-His Ala-Thr-Lys-Pro-Gly-His 238 Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Arg- Ala-Thr-Lys-Pro-Gly-Arg- 239 Arg-His His His Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Phe- Ala-Thr-Lys-Pro-Gly-Phe- 240 Phe-His His His Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Tyr- Ala-Thr-Lys-Pro-Gly-Tyr- 241 Tyr-His His His Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- 242 His His His Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- 243 His His His Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Lys- Ala-Thr-Lys-Pro-Gly-Lys- 244 Lys-His His His Ala-Thr-Lys-Pro-Asp-His Ala-Thr-Lys-Pro-Asp-His Ala-Thr-Lys-Pro-Asp-His 245 Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Arg- Ala-Thr-Lys-Pro-Asp- 246 Arg-His His Arg-His Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Phe- Ala-Thr-Lys-Pro-Asp- 247 Phe-His His Phe-His Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Tyr- Ala-Thr-Lys-Pro-Asp-Tyr- 248 Tyr-His His His Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-His- Ala-Thr-Lys-Pro-Asp-His- 249 His-His His His Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Pro- Ala-Thr-Lys-Pro-Asp-Pro- 250 Pro-His His His Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Lys- Ala-Thr-Lys-Pro-Asp- 251 Lys-His His Lys-His Ala-Thr-Lys-Pro-Trp-His Ala-Thr-Lys-Pro-Trp-His Ala-Thr-Lys-Pro-Trp-His 252 Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Arg- Ala-Thr-Lys-Pro-Trp-Arg- 253 Arg-His His His Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Phe- Ala-Thr-Lys-Pro-Trp-Phe- 254 Phe-His His His Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- 255 His His His Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- 256 His His His Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- 257 His His His Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Lys- Ala-Thr-Lys-Pro-Trp-Lys- 258 Lys-His His His Ala-Thr-Lys-Pro-Gln-His Ala-Thr-Lys-Pro-Gln-His Ala-Thr-Lys-Pro-Gln-His 259 Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Arg- Ala-Thr-Lys-Pro-Gln-Arg- 260 Arg-His His His Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Phe- Ala-Thr-Lys-Pro-Gln-Phe- 261 Phe-His His His Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Tyr- Ala-Thr-Lys-Pro-Gln-Tyr- 262 Tyr-His His His Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- 263 His His His Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- 264 His His His Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Lys- Ala-Thr-Lys-Pro-Gln-Lys- 265 Lys-His His His Ala-Thr-Lys-Pro-Asn-His Ala-Thr-Lys-Pro-Asn-His Ala-Thr-Lys-Pro-Asn-His 266 Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Arg- Ala-Thr-Lys-Pro-Asn- 267 Arg-His His Arg-His Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Phe- Ala-Thr-Lys-Pro-Asn- 268 Phe-His His Phe-His Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Tyr- Ala-Thr-Lys-Pro-Asn-Tyr- 269 Tyr-His His His Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-His- Ala-Thr-Lys-Pro-Asn-His- 270 His-His His His Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Pro- Ala-Thr-Lys-Pro-Asn-Pro- 271 Pro-His His His Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Lys- Ala-Thr-Lys-Pro-Asn- 272 Lys-His His Lys-His Ala-Thr-Lys-Pro-Tyr-His Ala-Thr-Lys-Pro-Tyr-His Ala-Thr-Lys-Pro-Tyr-His 273 Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Arg- Ala-Thr-Lys-Pro-Tyr-Arg- 274 Arg-His His His Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Phe- Ala-Thr-Lys-Pro-Tyr-Phe- 275 Phe-His His His Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- 276 His His His Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- 277 His His His Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- 278 His His His Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Lys- Ala-Thr-Lys-Pro-Tyr-Lys- 279 Lys-His His His Ala-Thr-Lys-Pro-Arg-His Ala-Thr-Lys-Pro-Arg-His Ala-Thr-Lys-Pro-Arg-His 280 Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Arg- Ala-Thr-Lys-Pro-Arg- 281 Arg-His His Arg-His Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Phe- Ala-Thr-Lys-Pro-Arg-Phe- 282 Phe-His His His Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Tyr- Ala-Thr-Lys-Pro-Arg-Tyr- 283 Tyr-His His His Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-His- Ala-Thr-Lys-Pro-Arg-His- 284 His-His His His Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Pro- Ala-Thr-Lys-Pro-Arg-Pro- 285 Pro-His His His Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Lys- Ala-Thr-Lys-Pro-Arg-Lys- 286 Lys-His His His His-Thr-Lys-Pro-His His-Thr-Lys-Pro-His His-Thr-Lys-Pro-His 287 His-Thr-Lys-Pro-Arg-His His-Thr-Lys-Pro-Arg-His His-Thr-Lys-Pro-Arg-His 288 His-Thr-Lys-Pro-Phe-His His-Thr-Lys-Pro-Phe-His His-Thr-Lys-Pro-Phe-His 289 His-Thr-Lys-Pro-Tyr-His His-Thr-Lys-Pro-Tyr-His His-Thr-Lys-Pro-Tyr-His 290 His-Thr-Lys-Pro-Gly-His His-Thr-Lys-Pro-Gly-His His-Thr-Lys-Pro-Gly-His 291 His-Thr-Lys-Pro-His-His His-Thr-Lys-Pro-His-His His-Thr-Lys-Pro-His-His 292 His-Thr-Lys-Pro-Lys-His His-Thr-Lys-Pro-Lys-His His-Thr-Lys-Pro-Lys-His 293 His-Thr-Lys-Pro-Gly-His His-Thr-Lys-Pro-Gly-His His-Thr-Lys-Pro-Gly-His 294 His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Arg- His-Thr-Lys-Pro-Gly-Arg- 295 Arg-His His His His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Phe- His-Thr-Lys-Pro-Gly-Phe- 296 Phe-His His His His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- 297 His His His His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- 298 His His His His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- 299 His His His His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Lys- His-Thr-Lys-Pro-Gly-Lys- 300 Lys-His His His

His-Thr-Lys-Pro-Asp-His His-Thr-Lys-Pro-Asp-His His-Thr-Lys-Pro-Asp-His 301 His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Arg- His-Thr-Lys-Pro-Asp- 302 Arg-His His Arg-His His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Phe- His-Thr-Lys-Pro-Asp-Phe- 303 Phe-His His His His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Tyr- His-Thr-Lys-Pro-Asp-Tyr- 304 Tyr-His His His His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-His- His-Thr-Lys-Pro-Asp-His- 305 His-His His His His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Pro- His-Thr-Lys-Pro-Asp-Pro- 306 Pro-His His His His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Lys- His-Thr-Lys-Pro-Asp-Lys- 307 Lys-His His His His-Thr-Lys-Pro-Trp-His His-Thr-Lys-Pro-Trp-His His-Thr-Lys-Pro-Trp-His 308 His-Thr-Lys-Pro-Trp- His-Thr-Lys-Pro-Trp-Arg- His-Thr-Lys-Pro-Trp-Arg- 309 Arg-His His His His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- 310 His His His His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- 311 His His His His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- 312 His His His His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- 313 His His His His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- 314 His His His His-Thr-Lys-Pro-Gln-His His-Thr-Lys-Pro-Gln-His His-Thr-Lys-Pro-Gln-His 315 His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Arg- His-Thr-Lys-Pro-Gln-Arg- 316 Arg-His His His His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Phe- His-Thr-Lys-Pro-Gln-Phe- 317 Phe-His His His His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- 318 His His His His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- 319 His His His His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- 320 His His His His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Lys- His-Thr-Lys-Pro-Gln-Lys- 321 Lys-His His His His-Thr-Lys-Pro-Asn-His His-Thr-Lys-Pro-Asn-His His-Thr-Lys-Pro-Asn-His 322 His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Arg- His-Thr-Lys-Pro-Asn- 323 Arg-His His Arg-His His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Phe- His-Thr-Lys-Pro-Asn-Phe- 324 Phe-His His His His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Tyr- His-Thr-Lys-Pro-Asn-Tyr- 325 Tyr-His His His His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-His- His-Thr-Lys-Pro-Asn-His- 326 His-His His His His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Pro- His-Thr-Lys-Pro-Asn-Pro- 327 Pro-His His His His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Lys- His-Thr-Lys-Pro-Asn-Lys- 328 Lys-His His His His-Thr-Lys-Pro-Tyr-His His-Thr-Lys-Pro-Tyr-His His-Thr-Lys-Pro-Tyr-His 329 His-Thr-Lys-Pro-Tyr- His-Thr-Lys-Pro-Tyr-Arg- His-Thr-Lys-Pro-Tyr-Arg- 330 Arg-His His His His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- 331 His His His His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- 332 His His His His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- 333 His His His His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- 334 His His His His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- 335 His His His His-Thr-Lys-Pro-Arg-His His-Thr-Lys-Pro-Arg-His His-Thr-Lys-Pro-Arg-His 336 His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Arg- His-Thr-Lys-Pro-Arg-Arg- 337 Arg-His His His His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Phe- His-Thr-Lys-Pro-Arg-Phe- 338 Phe-His His His His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Tyr- His-Thr-Lys-Pro-Arg-Tyr- 339 Tyr-His His His His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- 340 His His His His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- 341 His His His His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Lys- His-Thr-Lys-Pro-Arg-Lys- 342 Lys-His His His Lys-Thr-Lys-Pro-His Lys-Thr-Lys-Pro-His Lys-Thr-Lys-Pro-His 343 Lys-Thr-Lys-Pro-Arg-His Lys-Thr-Lys-Pro-Arg-His Lys-Thr-Lys-Pro-Arg-His 344 Lys-Thr-Lys-Pro-Phe-His Lys-Thr-Lys-Pro-Phe-His Lys-Thr-Lys-Pro-Phe-His 345 Lys-Thr-Lys-Pro-Tyr-His Lys-Thr-Lys-Pro-Tyr-His Lys-Thr-Lys-Pro-Tyr-His 346 Lys-Thr-Lys-Pro-Gly-His Lys-Thr-Lys-Pro-Gly-His Lys-Thr-Lys-Pro-Gly-His 347 Lys-Thr-Lys-Pro-His-His Lys-Thr-Lys-Pro-His-His Lys-Thr-Lys-Pro-His-His 348 Lys-Thr-Lys-Pro-Lys-His Lys-Thr-Lys-Pro-Lys-His Lys-Thr-Lys-Pro-Lys-His 349 Lys-Thr-Lys-Pro-Gly-His Lys-Thr-Lys-Pro-Gly-His Lys-Thr-Lys-Pro-Gly-His 350 Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Arg- Lys-Thr-Lys-Pro-Gly- 351 Arg-His His Arg-His Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Phe- Lys-Thr-Lys-Pro-Gly-Phe- 352 Phe-His His His Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Tyr- Lys-Thr-Lys-Pro-Gly-Tyr- 353 Tyr-His His His Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-His- Lys-Thr-Lys-Pro-Gly-His- 354 His-His His His Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Pro- Lys-Thr-Lys-Pro-Gly-Pro- 355 Pro-His His His Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Lys- Lys-Thr-Lys-Pro-Gly-Lys- 356 Lys-His His His Lys-Thr-Lys-Pro-Asp-His Lys-Thr-Lys-Pro-Asp-His Lys-Thr-Lys-Pro-Asp-His 357 Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Arg- Lys-Thr-Lys-Pro-Asp- 358 Arg-His His Arg-His Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Phe- Lys-Thr-Lys-Pro-Asp- 359 Phe-His His Phe-His Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Tyr- Lys-Thr-Lys-Pro-Asp- 360 Tyr-His His Tyr-His Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-His- Lys-Thr-Lys-Pro-Asp-His- 361 His-His His His Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Pro- Lys-Thr-Lys-Pro-Asp-Pro- 362 Pro-His His His Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Lys- Lys-Thr-Lys-Pro-Asp- 363 Lys-His His Lys-His Lys-Thr-Lys-Pro-Trp-His Lys-Thr-Lys-Pro-Trp-His Lys-Thr-Lys-Pro-Trp-His 364 Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Arg- Lys-Thr-Lys-Pro-Trp-Arg- 365 Arg-His His His Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Phe- Lys-Thr-Lys-Pro-Trp-Phe- 366 Phe-His His His Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Tyr- Lys-Thr-Lys-Pro-Trp-Tyr- 367 Tyr-His His His Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- 368 His His His Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- 369 His His His

Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Lys- Lys-Thr-Lys-Pro-Trp-Lys- 370 Lys-His His His Lys-Thr-Lys-Pro-Gln-His Lys-Thr-Lys-Pro-Gln-His Lys-Thr-Lys-Pro-Gln-His 371 Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Arg- Lys-Thr-Lys-Pro-Gln- 372 Arg-His His Arg-His Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Phe- Lys-Thr-Lys-Pro-Gln-Phe- 373 Phe-His His His Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Tyr- Lys-Thr-Lys-Pro-Gln-Tyr- 374 Tyr-His His His Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-His- Lys-Thr-Lys-Pro-Gln-His- 375 His-His His His Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Pro- Lys-Thr-Lys-Pro-Gln-Pro- 376 Pro-His His His Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Lys- Lys-Thr-Lys-Pro-Gln-Lys- 377 Lys-His His His Lys-Thr-Lys-Pro-Asn-His Lys-Thr-Lys-Pro-Asn-His Lys-Thr-Lys-Pro-Asn-His 378 Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Arg- Lys-Thr-Lys-Pro-Asn- 379 Arg-His His Arg-His Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Phe- Lys-Thr-Lys-Pro-Asn- 380 Phe-His His Phe-His Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Tyr- Lys-Thr-Lys-Pro-Asn- 381 Tyr-His His Tyr-His Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-His- Lys-Thr-Lys-Pro-Asn-His- 382 His-His His His Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Pro- Lys-Thr-Lys-Pro-Asn-Pro- 383 Pro-His His His Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Lys- Lys-Thr-Lys-Pro-Asn- 384 Lys-His His Lys-His Lys-Thr-Lys-Pro-Tyr-His Lys-Thr-Lys-Pro-Tyr-His Lys-Thr-Lys-Pro-Tyr-His 385 Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Arg- Lys-Thr-Lys-Pro-Tyr-Arg- 386 Arg-His His His Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Phe- Lys-Thr-Lys-Pro-Tyr-Phe- 387 Phe-His His His Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- 388 Tyr-His His His Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- 389 His His His Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- 390 His His His Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Lys- Lys-Thr-Lys-Pro-Tyr-Lys- 391 Lys-His His His Lys-Thr-Lys-Pro-Arg-His Lys-Thr-Lys-Pro-Arg-His Lys-Thr-Lys-Pro-Arg-His 392 Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Arg- Lys-Thr-Lys-Pro-Arg- 393 Arg-His His Arg-His Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Phe- Lys-Thr-Lys-Pro-Arg- 394 Phe-His His Phe-His Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Tyr- Lys-Thr-Lys-Pro-Arg-Tyr- 395 Tyr-His His His Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-His- Lys-Thr-Lys-Pro-Arg-His- 396 His-His His His Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Pro- Lys-Thr-Lys-Pro-Arg-Pro- 397 Pro-His His His Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Lys- Lys-Thr-Lys-Pro-Arg- 398 Lys-His His Lys-His Gly-Thr-Lys-Pro-His Gly-Thr-Lys-Pro-His Gly-Thr-Lys-Pro-His 399 Gly-Thr-Lys-Pro-Arg-His Gly-Thr-Lys-Pro-Arg-His Gly-Thr-Lys-Pro-Arg-His 400 Gly-Thr-Lys-Pro-Phe-His Gly-Thr-Lys-Pro-Phe-His Gly-Thr-Lys-Pro-Phe-His 401 Gly-Thr-Lys-Pro-Tyr-His Gly-Thr-Lys-Pro-Tyr-His Gly-Thr-Lys-Pro-Tyr-His 402 Gly-Thr-Lys-Pro-Gly-His Gly-Thr-Lys-Pro-Gly-His Gly-Thr-Lys-Pro-Gly-His 403 Gly-Thr-Lys-Pro-His-His Gly-Thr-Lys-Pro-His-His Gly-Thr-Lys-Pro-His-His 404 Gly-Thr-Lys-Pro-Lys-His Gly-Thr-Lys-Pro-Lys-His Gly-Thr-Lys-Pro-Lys-His 405 Gly-Thr-Lys-Pro-Gly-His Gly-Thr-Lys-Pro-Gly-His Gly-Thr-Lys-Pro-Gly-His 406 Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Arg- Gly-Thr-Lys-Pro-Gly- 407 Arg-His His Arg-His Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Phe- Gly-Thr-Lys-Pro-Gly-Phe- 408 Phe-His His His Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Tyr- Gly-Thr-Lys-Pro-Gly-Tyr- 409 Tyr-His His His Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-His- Gly-Thr-Lys-Pro-Gly-His- 410 His-His His His Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Pro- Gly-Thr-Lys-Pro-Gly-Pro- 411 Pro-His His His Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Lys- Gly-Thr-Lys-Pro-Gly-Lys- 412 Lys-His His His Gly-Thr-Lys-Pro-Asp-His Gly-Thr-Lys-Pro-Asp-His Gly-Thr-Lys-Pro-Asp-His 413 Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Arg- Gly-Thr-Lys-Pro-Asp- 414 Arg-His His Arg-His Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Phe- Gly-Thr-Lys-Pro-Asp- 415 Phe-His His Phe-His Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Tyr- Gly-Thr-Lys-Pro-Asp- 416 Tyr-His His Tyr-His Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-His- Gly-Thr-Lys-Pro-Asp-His- 417 His-His His His Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Pro- Gly-Thr-Lys-Pro-Asp-Pro- 418 Pro-His His His Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Lys- Gly-Thr-Lys-Pro-Asp- 419 Lys-His His Lys-His Gly-Thr-Lys-Pro-Trp-His Gly-Thr-Lys-Pro-Trp-His Gly-Thr-Lys-Pro-Trp-His 420 Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Arg- Gly-Thr-Lys-Pro-Trp-Arg- 421 Arg-His His His Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Phe- Gly-Thr-Lys-Pro-Trp-Phe- 422 Phe-His His His Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Tyr- Gly-Thr-Lys-Pro-Trp-Tyr- 423 Tyr-His His His Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- 424 His His His Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- 425 His His His Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Lys- Gly-Thr-Lys-Pro-Trp-Lys- 426 Lys-His His His Gly-Thr-Lys-Pro-Gln-His Gly-Thr-Lys-Pro-Gln-His Gly-Thr-Lys-Pro-Gln-His 427 Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Arg- Gly-Thr-Lys-Pro-Gln- 428 Arg-His His Arg-His Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Phe- Gly-Thr-Lys-Pro-Gln-Phe- 429 Phe-His His His Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Tyr- Gly-Thr-Lys-Pro-Gln-Tyr- 430 Tyr-His His His Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-His- Gly-Thr-Lys-Pro-Gln-His- 431 His-His His His Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Pro- Gly-Thr-Lys-Pro-Gln-Pro- 432 Pro-His His His Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Lys- Gly-Thr-Lys-Pro-Gln-Lys- 433 Lys-His His His Gly-Thr-Lys-Pro-Asn-His Gly-Thr-Lys-Pro-Asn-His Gly-Thr-Lys-Pro-Asn-His 434 Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Arg- Gly-Thr-Lys-Pro-Asn- 435 Arg-His His Arg-His Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Phe- Gly-Thr-Lys-Pro-Asn- 436 Phe-His His Phe-His Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Tyr- Gly-Thr-Lys-Pro-Asn- 437 Tyr-His His Tyr-His Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-His- Gly-Thr-Lys-Pro-Asn-His- 438 His-His His His Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Pro- Gly-Thr-Lys-Pro-Asn-Pro- 439 Pro-His His His Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Lys- Gly-Thr-Lys-Pro-Asn- 440 Lys-His His Lys-His Gly-Thr-Lys-Pro-Tyr-His Gly-Thr-Lys-Pro-Tyr-His Gly-Thr-Lys-Pro-Tyr-His

441 Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Arg- Gly-Thr-Lys-Pro-Tyr-Arg- 442 Arg-His His His Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Phe- Gly-Thr-Lys-Pro-Tyr-Phe- 443 Phe-His His His Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- 444 Tyr-His His His Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- 445 His His His Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- 446 His His His Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Lys- Gly-Thr-Lys-Pro-Tyr-Lys- 447 Lys-His His His Gly-Thr-Lys-Pro-Arg-His Gly-Thr-Lys-Pro-Arg-His Gly-Thr-Lys-Pro-Arg-His 448 Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Arg- Gly-Thr-Lys-Pro-Arg- 449 Arg-His His Arg-His Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Phe- Gly-Thr-Lys-Pro-Arg- 450 Phe-His His Phe-His Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Tyr- Gly-Thr-Lys-Pro-Arg-Tyr- 451 Tyr-His His His Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-His- Gly-Thr-Lys-Pro-Arg-His- 452 His-His His His Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Pro- Gly-Thr-Lys-Pro-Arg-Pro- 453 Pro-His His His Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Lys- Gly-Thr-Lys-Pro-Arg- 454 Lys-His His Lys-His Thr-Lys-Pro Thr-Lys-Pro Thr-Lys-Pro 455 Thr-Lys-Pro-Gly-Arg Thr-Lys-Pro-Gly-Arg Thr-Lys-Pro-Gly-Arg 456 Thr-Lys-Pro-Gly-Phe Thr-Lys-Pro-Gly-Phe Thr-Lys-Pro-Gly-Phe 457 Thr-Lys-Pro-Gly-Tyr Thr-Lys-Pro-Gly-Tyr Thr-Lys-Pro-Gly-Tyr 458 Thr-Lys-Pro-Gly-His Thr-Lys-Pro-Gly-His Thr-Lys-Pro-Gly-His 459 Thr-Lys-Pro-Gly-Pro Thr-Lys-Pro-Gly-Pro Thr-Lys-Pro-Gly-Pro 460 Thr-Lys-Pro-Gly-Lys Thr-Lys-Pro-Gly-Lys Thr-Lys-Pro-Gly-Lys 461 Thr-Lys-Pro-Asp-Arg Thr-Lys-Pro-Asp-Arg Thr-Lys-Pro-Asp-Arg 462 Thr-Lys-Pro-Asp-Phe Thr-Lys-Pro-Asp-Phe Thr-Lys-Pro-Asp-Phe 463 Thr-Lys-Pro-Asp-Tyr Thr-Lys-Pro-Asp-Tyr Thr-Lys-Pro-Asp-Tyr 464 Thr-Lys-Pro-Asp-His Thr-Lys-Pro-Asp-His Thr-Lys-Pro-Asp-His 465 Thr-Lys-Pro-Asp-Pro Thr-Lys-Pro-Asp-Pro Thr-Lys-Pro-Asp-Pro 466 Thr-Lys-Pro-Asp-Lys Thr-Lys-Pro-Asp-Lys Thr-Lys-Pro-Asp-Lys 467 Thr-Lys-Pro-Trp-Arg Thr-Lys-Pro-Trp-Arg Thr-Lys-Pro-Trp-Arg 468 Thr-Lys-Pro-Trp-Phe Thr-Lys-Pro-Trp-Phe Thr-Lys-Pro-Trp-Phe 469 Thr-Lys-Pro-Trp-Tyr Thr-Lys-Pro-Trp-Tyr Thr-Lys-Pro-Trp-Tyr 470 Thr-Lys-Pro-Trp-His Thr-Lys-Pro-Trp-His Thr-Lys-Pro-Trp-His 471 Thr-Lys-Pro-Trp-Pro Thr-Lys-Pro-Trp-Pro Thr-Lys-Pro-Trp-Pro 472 Thr-Lys-Pro-Trp-Lys Thr-Lys-Pro-Trp-Lys Thr-Lys-Pro-Trp-Lys 473 Thr-Lys-Pro-Gln-Arg Thr-Lys-Pro-Gln-Arg Thr-Lys-Pro-Gln-Arg 474 Thr-Lys-Pro-Gln-Phe Thr-Lys-Pro-Gln-Phe Thr-Lys-Pro-Gln-Phe 475 Thr-Lys-Pro-Gln-Tyr Thr-Lys-Pro-Gln-Tyr Thr-Lys-Pro-Gln-Tyr 476 Thr-Lys-Pro-Gln-His Thr-Lys-Pro-Gln-His Thr-Lys-Pro-Gln-His 477 Thr-Lys-Pro-Gln-Pro Thr-Lys-Pro-Gln-Pro Thr-Lys-Pro-Gln-Pro 478 Thr-Lys-Pro-Gln-Lys Thr-Lys-Pro-Gln-Lys Thr-Lys-Pro-Gln-Lys 479 Thr-Lys-Pro-Asn-Arg Thr-Lys-Pro-Asn-Arg Thr-Lys-Pro-Asn-Arg 480 Thr-Lys-Pro-Asn-Phe Thr-Lys-Pro-Asn-Phe Thr-Lys-Pro-Asn-Phe 481 Thr-Lys-Pro-Asn-Tyr Thr-Lys-Pro-Asn-Tyr Thr-Lys-Pro-Asn-Tyr 482 Thr-Lys-Pro-Asn-His Thr-Lys-Pro-Asn-His Thr-Lys-Pro-Asn-His 483 Thr-Lys-Pro-Asn-Pro Thr-Lys-Pro-Asn-Pro Thr-Lys-Pro-Asn-Pro 484 Thr-Lys-Pro-Asn-Lys Thr-Lys-Pro-Asn-Lys Thr-Lys-Pro-Asn-Lys 485 Thr-Lys-Pro-Tyr-Arg Thr-Lys-Pro-Tyr-Arg Thr-Lys-Pro-Tyr-Arg 486 Thr-Lys-Pro-Tyr-Phe Thr-Lys-Pro-Tyr-Phe Thr-Lys-Pro-Tyr-Phe 487 Thr-Lys-Pro-Tyr-Tyr Thr-Lys-Pro-Tyr-Tyr Thr-Lys-Pro-Tyr-Tyr 488 Thr-Lys-Pro-Tyr-His Thr-Lys-Pro-Tyr-His Thr-Lys-Pro-Tyr-His 489 Thr-Lys-Pro-Tyr-Pro Thr-Lys-Pro-Tyr-Pro Thr-Lys-Pro-Tyr-Pro 490 Thr-Lys-Pro-Tyr-Lys Thr-Lys-Pro-Tyr-Lys Thr-Lys-Pro-Tyr-Lys 491 Thr-Lys-Pro-Arg-Arg Thr-Lys-Pro-Arg-Arg Thr-Lys-Pro-Arg-Arg 492 Thr-Lys-Pro-Arg-Phe Thr-Lys-Pro-Arg-Phe Thr-Lys-Pro-Arg-Phe 493 Thr-Lys-Pro-Arg-Tyr Thr-Lys-Pro-Arg-Tyr Thr-Lys-Pro-Arg-Tyr 494 Thr-Lys-Pro-Arg-His Thr-Lys-Pro-Arg-His Thr-Lys-Pro-Arg-His 495 Thr-Lys-Pro-Arg-Pro Thr-Lys-Pro-Arg-Pro Thr-Lys-Pro-Arg-Pro 6 Thr-Lys-Pro-Arg-Lys Thr-Lys-Pro-Arg-Lys Thr-Lys-Pro-Arg-Lys 496 Met-Thr-Lys-Pro-Arg Met-Thr-Lys-Pro-Arg Met-Thr-Lys-Pro-Arg 497 Met-Thr-Lys-Pro-Phe Met-Thr-Lys-Pro-Phe Met-Thr-Lys-Pro-Phe 498 Met-Thr-Lys-Pro-Tyr Met-Thr-Lys-Pro-Tyr Met-Thr-Lys-Pro-Tyr 499 Met-Thr-Lys-Pro-Gly Met-Thr-Lys-Pro-Gly Met-Thr-Lys-Pro-Gly 500 Met-Thr-Lys-Pro-His Met-Thr-Lys-Pro-His Met-Thr-Lys-Pro-His 501 Met-Thr-Lys-Pro-Lys Met-Thr-Lys-Pro-Lys Met-Thr-Lys-Pro-Lys 502 Met-Thr-Lys-Pro-Gly Met-Thr-Lys-Pro-Gly Met-Thr-Lys-Pro-Gly 503 Met-Thr-Lys-Pro-Gly-Arg Met-Thr-Lys-Pro-Gly-Arg Met-Thr-Lys-Pro-Gly-Arg 504 Met-Thr-Lys-Pro-Gly-Phe Met-Thr-Lys-Pro-Gly-Phe Met-Thr-Lys-Pro-Gly-Phe 505 Met-Thr-Lys-Pro-Gly-Tyr Met-Thr-Lys-Pro-Gly-Tyr Met-Thr-Lys-Pro-Gly-Tyr 506 Met-Thr-Lys-Pro-Gly-His Met-Thr-Lys-Pro-Gly-His Met-Thr-Lys-Pro-Gly-His 507 Met-Thr-Lys-Pro-Gly-Pro Met-Thr-Lys-Pro-Gly-Pro Met-Thr-Lys-Pro-Gly-Pro 508 Met-Thr-Lys-Pro-Gly-Lys Met-Thr-Lys-Pro-Gly-Lys Met-Thr-Lys-Pro-Gly-Lys 509 Met-Thr-Lys-Pro-Asp Met-Thr-Lys-Pro-Asp Met-Thr-Lys-Pro-Asp 510 Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Arg Met-Thr-Lys-Pro-Asp-Arg 511 Arg Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Phe Met-Thr-Lys-Pro-Asp-Phe 512 Phe Met-Thr-Lys-Pro-Asp-Tyr Met-Thr-Lys-Pro-Asp-Tyr Met-Thr-Lys-Pro-Asp-Tyr 513 Met-Thr-Lys-Pro-Asp-His Met-Thr-Lys-Pro-Asp-His Met-Thr-Lys-Pro-Asp-His 514 Met-Thr-Lys-Pro-Asp-Pro Met-Thr-Lys-Pro-Asp-Pro Met-Thr-Lys-Pro-Asp-Pro 515 Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Lys Met-Thr-Lys-Pro-Asp-Lys 516 Lys Met-Thr-Lys-Pro-Trp Met-Thr-Lys-Pro-Trp Met-Thr-Lys-Pro-Trp 517 Met-Thr-Lys-Pro-Trp-Arg Met-Thr-Lys-Pro-Trp-Arg Met-Thr-Lys-Pro-Trp-Arg 518 Met-Thr-Lys-Pro-Trp-Phe Met-Thr-Lys-Pro-Trp-Phe Met-Thr-Lys-Pro-Trp-Phe 519 Met-Thr-Lys-Pro-Trp-Tyr Met-Thr-Lys-Pro-Trp-Tyr Met-Thr-Lys-Pro-Trp-Tyr 520 Met-Thr-Lys-Pro-Trp-His Met-Thr-Lys-Pro-Trp-His Met-Thr-Lys-Pro-Trp-His 521 Met-Thr-Lys-Pro-Trp-Pro Met-Thr-Lys-Pro-Trp-Pro Met-Thr-Lys-Pro-Trp-Pro 522 Met-Thr-Lys-Pro-Trp-Lys Met-Thr-Lys-Pro-Trp-Lys Met-Thr-Lys-Pro-Trp-Lys 523 Met-Thr-Lys-Pro-Gln Met-Thr-Lys-Pro-Gln Met-Thr-Lys-Pro-Gln 524 Met-Thr-Lys-Pro-Gln-Arg Met-Thr-Lys-Pro-Gln-Arg Met-Thr-Lys-Pro-Gln-Arg 525 Met-Thr-Lys-Pro-Gln-Phe Met-Thr-Lys-Pro-Gln-Phe Met-Thr-Lys-Pro-Gln-Phe 526 Met-Thr-Lys-Pro-Gln-Tyr Met-Thr-Lys-Pro-Gln-Tyr Met-Thr-Lys-Pro-Gln-Tyr 527 Met-Thr-Lys-Pro-Gln-His Met-Thr-Lys-Pro-Gln-His Met-Thr-Lys-Pro-Gln-His 528 Met-Thr-Lys-Pro-Gln-Pro Met-Thr-Lys-Pro-Gln-Pro Met-Thr-Lys-Pro-Gln-Pro 529 Met-Thr-Lys-Pro-Gln-Lys Met-Thr-Lys-Pro-Gln-Lys Met-Thr-Lys-Pro-Gln-Lys 530 Met-Thr-Lys-Pro-Asn Met-Thr-Lys-Pro-Asn Met-Thr-Lys-Pro-Asn 531 Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Arg Met-Thr-Lys-Pro-Asn-Arg 532 Arg Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Phe Met-Thr-Lys-Pro-Asn-Phe 533 Phe Met-Thr-Lys-Pro-Asn-Tyr Met-Thr-Lys-Pro-Asn-Tyr Met-Thr-Lys-Pro-Asn-Tyr 534 Met-Thr-Lys-Pro-Asn-His Met-Thr-Lys-Pro-Asn-His Met-Thr-Lys-Pro-Asn-His 535 Met-Thr-Lys-Pro-Asn-Pro Met-Thr-Lys-Pro-Asn-Pro Met-Thr-Lys-Pro-Asn-Pro 536 Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Lys Met-Thr-Lys-Pro-Asn-Lys 537 Lys Met-Thr-Lys-Pro-Tyr Met-Thr-Lys-Pro-Tyr Met-Thr-Lys-Pro-Tyr 538 Met-Thr-Lys-Pro-Tyr-Arg Met-Thr-Lys-Pro-Tyr-Arg Met-Thr-Lys-Pro-Tyr-Arg

539 Met-Thr-Lys-Pro-Tyr-Phe Met-Thr-Lys-Pro-Tyr-Phe Met-Thr-Lys-Pro-Tyr-Phe 540 Met-Thr-Lys-Pro-Tyr-Tyr Met-Thr-Lys-Pro-Tyr-Tyr Met-Thr-Lys-Pro-Tyr-Tyr 541 Met-Thr-Lys-Pro-Tyr-His Met-Thr-Lys-Pro-Tyr-His Met-Thr-Lys-Pro-Tyr-His 542 Met-Thr-Lys-Pro-Tyr-Pro Met-Thr-Lys-Pro-Tyr-Pro Met-Thr-Lys-Pro-Tyr-Pro 543 Met-Thr-Lys-Pro-Tyr-Lys Met-Thr-Lys-Pro-Tyr-Lys Met-Thr-Lys-Pro-Tyr-Lys 544 Met-Thr-Lys-Pro-Arg Met-Thr-Lys-Pro-Arg Met-Thr-Lys-Pro-Arg 545 Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Arg Met-Thr-Lys-Pro-Arg-Arg 546 Arg Met-Thr-Lys-Pro-Arg-Phe Met-Thr-Lys-Pro-Arg-Phe Met-Thr-Lys-Pro-Arg-Phe 547 Met-Thr-Lys-Pro-Arg-Tyr Met-Thr-Lys-Pro-Arg-Tyr Met-Thr-Lys-Pro-Arg-Tyr 548 Met-Thr-Lys-Pro-Arg-His Met-Thr-Lys-Pro-Arg-His Met-Thr-Lys-Pro-Arg-His 549 Met-Thr-Lys-Pro-Arg-Pro Met-Thr-Lys-Pro-Arg-Pro Met-Thr-Lys-Pro-Arg-Pro 550 Met-Thr-Lys-Pro-Arg-Lys Met-Thr-Lys-Pro-Arg-Lys Met-Thr-Lys-Pro-Arg-Lys 551 Met(O)-Thr-Lys-Pro-Arg Met(O)-Thr-Lys-Pro-Arg Met(O)-Thr-Lys-Pro-Arg 552 Met(O)-Thr-Lys-Pro-Phe Met(O)-Thr-Lys-Pro-Phe Met(O)-Thr-Lys-Pro-Phe 553 Met(O)-Thr-Lys-Pro-Tyr Met(O)-Thr-Lys-Pro-Tyr Met(O)-Thr-Lys-Pro-Tyr 554 Met(O)-Thr-Lys-Pro-Gly Met(O)-Thr-Lys-Pro-Gly Met(O)-Thr-Lys-Pro-Gly 555 Met(O)-Thr-Lys-Pro-His Met(O)-Thr-Lys-Pro-His Met(O)-Thr-Lys-Pro-His 556 Met(O)-Thr-Lys-Pro-Lys Met(O)-Thr-Lys-Pro-Lys Met(O)-Thr-Lys-Pro-Lys 557 Met(O)-Thr-Lys-Pro-Gly Met(O)-Thr-Lys-Pro-Gly Met(O)-Thr-Lys-Pro-Gly 558 Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 559 Arg Arg Arg Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 560 Phe Phe Phe Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 561 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 562 His His His Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 563 Pro Pro Pro Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 564 Lys Lys Lys Met(O)-Thr-Lys-Pro-Asp Met(O)-Thr-Lys-Pro-Asp Met(O)-Thr-Lys-Pro-Asp 565 Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 566 Arg Arg Arg Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 567 Phe Phe Phe Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 568 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 569 His His His Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 570 Pro Pro Pro Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 571 Lys Lys Lys Met(O)-Thr-Lys-Pro-Trp Met(O)-Thr-Lys-Pro-Trp Met(O)-Thr-Lys-Pro-Trp 572 Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 573 Arg Arg Arg Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 574 Phe Phe Phe Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 575 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 576 His His His Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 577 Pro Pro Pro Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 578 Lys Lys Lys Met(O)-Thr-Lys-Pro-Gln Met(O)-Thr-Lys-Pro-Gln Met(O)-Thr-Lys-Pro-Gln 579 Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 580 Arg Arg Arg Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 581 Phe Phe Phe Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 582 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 583 His His His Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 584 Pro Pro Pro Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 585 Lys Lys Lys Met(O)-Thr-Lys-Pro-Asn Met(O)-Thr-Lys-Pro-Asn Met(O)-Thr-Lys-Pro-Asn 586 Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 587 Arg Arg Arg Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 588 Phe Phe Phe Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 589 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 590 His His His Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 591 Pro Pro Pro Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 592 Lys Lys Lys Met(O)-Thr-Lys-Pro-Tyr Met(O)-Thr-Lys-Pro-Tyr Met(O)-Thr-Lys-Pro-Tyr 593 Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 594 Arg Arg Arg Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 595 Phe Phe Phe Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 596 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 597 His His His Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 598 Pro Pro Pro Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 599 Lys Lys Lys Met(O)-Thr-Lys-Pro-Arg Met(O)-Thr-Lys-Pro-Arg Met(O)-Thr-Lys-Pro-Arg 600 Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 601 Arg Arg Arg Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 602 Phe Phe Phe Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 603 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 604 His His His Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 605 Pro Pro Pro Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 606 Lys Lys Lys Thr-Thr-Lys-Pro-Arg Thr-Thr-Lys-Pro-Arg Thr-Thr-Lys-Pro-Arg 607 Thr-Thr-Lys-Pro-Phe Thr-Thr-Lys-Pro-Phe Thr-Thr-Lys-Pro-Phe 608 Thr-Thr-Lys-Pro-Tyr Thr-Thr-Lys-Pro-Tyr Thr-Thr-Lys-Pro-Tyr 609 Thr-Thr-Lys-Pro-Gly Thr-Thr-Lys-Pro-Gly Thr-Thr-Lys-Pro-Gly 610 Thr-Thr-Lys-Pro-His Thr-Thr-Lys-Pro-His Thr-Thr-Lys-Pro-His 611 Thr-Thr-Lys-Pro-Lys Thr-Thr-Lys-Pro-Lys Thr-Thr-Lys-Pro-Lys 612 Thr-Thr-Lys-Pro-Gly Thr-Thr-Lys-Pro-Gly Thr-Thr-Lys-Pro-Gly 613 Thr-Thr-Lys-Pro-Gly-Arg Thr-Thr-Lys-Pro-Gly-Arg Thr-Thr-Lys-Pro-Gly-Arg 614 Thr-Thr-Lys-Pro-Gly-Phe Thr-Thr-Lys-Pro-Gly-Phe Thr-Thr-Lys-Pro-Gly-Phe 615

Thr-Thr-Lys-Pro-Gly-Tyr Thr-Thr-Lys-Pro-Gly-Tyr Thr-Thr-Lys-Pro-Gly-Tyr 616 Thr-Thr-Lys-Pro-Gly-His Thr-Thr-Lys-Pro-Gly-His Thr-Thr-Lys-Pro-Gly-His 617 Thr-Thr-Lys-Pro-Gly-Pro Thr-Thr-Lys-Pro-Gly-Pro Thr-Thr-Lys-Pro-Gly-Pro 618 Thr-Thr-Lys-Pro-Gly-Lys Thr-Thr-Lys-Pro-Gly-Lys Thr-Thr-Lys-Pro-Gly-Lys 619 Thr-Thr-Lys-Pro-Asp Thr-Thr-Lys-Pro-Asp Thr-Thr-Lys-Pro-Asp 620 Thr-Thr-Lys-Pro-Asp-Arg Thr-Thr-Lys-Pro-Asp-Arg Thr-Thr-Lys-Pro-Asp-Arg 621 Thr-Thr-Lys-Pro-Asp-Phe Thr-Thr-Lys-Pro-Asp-Phe Thr-Thr-Lys-Pro-Asp-Phe 622 Thr-Thr-Lys-Pro-Asp-Tyr Thr-Thr-Lys-Pro-Asp-Tyr Thr-Thr-Lys-Pro-Asp-Tyr 623 Thr-Thr-Lys-Pro-Asp-His Thr-Thr-Lys-Pro-Asp-His Thr-Thr-Lys-Pro-Asp-His 624 Thr-Thr-Lys-Pro-Asp-Pro Thr-Thr-Lys-Pro-Asp-Pro Thr-Thr-Lys-Pro-Asp-Pro 625 Thr-Thr-Lys-Pro-Asp-Lys Thr-Thr-Lys-Pro-Asp-Lys Thr-Thr-Lys-Pro-Asp-Lys 626 Thr-Thr-Lys-Pro-Trp Thr-Thr-Lys-Pro-Trp Thr-Thr-Lys-Pro-Trp 627 Thr-Thr-Lys-Pro-Trp-Arg Thr-Thr-Lys-Pro-Trp-Arg Thr-Thr-Lys-Pro-Trp-Arg 628 Thr-Thr-Lys-Pro-Trp-Phe Thr-Thr-Lys-Pro-Trp-Phe Thr-Thr-Lys-Pro-Trp-Phe 629 Thr-Thr-Lys-Pro-Trp-Tyr Thr-Thr-Lys-Pro-Trp-Tyr Thr-Thr-Lys-Pro-Trp-Tyr 630 Thr-Thr-Lys-Pro-Trp-His Thr-Thr-Lys-Pro-Trp-His Thr-Thr-Lys-Pro-Trp-His 631 Thr-Thr-Lys-Pro-Trp-Pro Thr-Thr-Lys-Pro-Trp-Pro Thr-Thr-Lys-Pro-Trp-Pro 632 Thr-Thr-Lys-Pro-Trp-Lys Thr-Thr-Lys-Pro-Trp-Lys Thr-Thr-Lys-Pro-Trp-Lys 633 Thr-Thr-Lys-Pro-Gln Thr-Thr-Lys-Pro-Gln Thr-Thr-Lys-Pro-Gln 634 Thr-Thr-Lys-Pro-Gln-Arg Thr-Thr-Lys-Pro-Gln-Arg Thr-Thr-Lys-Pro-Gln-Arg 635 Thr-Thr-Lys-Pro-Gln-Phe Thr-Thr-Lys-Pro-Gln-Phe Thr-Thr-Lys-Pro-Gln-Phe 636 Thr-Thr-Lys-Pro-Gln-Tyr Thr-Thr-Lys-Pro-Gln-Tyr Thr-Thr-Lys-Pro-Gln-Tyr 637 Thr-Thr-Lys-Pro-Gln-His Thr-Thr-Lys-Pro-Gln-His Thr-Thr-Lys-Pro-Gln-His 638 Thr-Thr-Lys-Pro-Gln-Pro Thr-Thr-Lys-Pro-Gln-Pro Thr-Thr-Lys-Pro-Gln-Pro 639 Thr-Thr-Lys-Pro-Gln-Lys Thr-Thr-Lys-Pro-Gln-Lys Thr-Thr-Lys-Pro-Gln-Lys 640 Thr-Thr-Lys-Pro-Asn Thr-Thr-Lys-Pro-Asn Thr-Thr-Lys-Pro-Asn 641 Thr-Thr-Lys-Pro-Asn-Arg Thr-Thr-Lys-Pro-Asn-Arg Thr-Thr-Lys-Pro-Asn-Arg 642 Thr-Thr-Lys-Pro-Asn-Phe Thr-Thr-Lys-Pro-Asn-Phe Thr-Thr-Lys-Pro-Asn-Phe 643 Thr-Thr-Lys-Pro-Asn-Tyr Thr-Thr-Lys-Pro-Asn-Tyr Thr-Thr-Lys-Pro-Asn-Tyr 644 Thr-Thr-Lys-Pro-Asn-His Thr-Thr-Lys-Pro-Asn-His Thr-Thr-Lys-Pro-Asn-His 645 Thr-Thr-Lys-Pro-Asn-Pro Thr-Thr-Lys-Pro-Asn-Pro Thr-Thr-Lys-Pro-Asn-Pro 646 Thr-Thr-Lys-Pro-Asn-Lys Thr-Thr-Lys-Pro-Asn-Lys Thr-Thr-Lys-Pro-Asn-Lys 647 Thr-Thr-Lys-Pro-Tyr Thr-Thr-Lys-Pro-Tyr Thr-Thr-Lys-Pro-Tyr 648 Thr-Thr-Lys-Pro-Tyr-Arg Thr-Thr-Lys-Pro-Tyr-Arg Thr-Thr-Lys-Pro-Tyr-Arg 649 Thr-Thr-Lys-Pro-Tyr-Phe Thr-Thr-Lys-Pro-Tyr-Phe Thr-Thr-Lys-Pro-Tyr-Phe 650 Thr-Thr-Lys-Pro-Tyr-Tyr Thr-Thr-Lys-Pro-Tyr-Tyr Thr-Thr-Lys-Pro-Tyr-Tyr 651 Thr-Thr-Lys-Pro-Tyr-His Thr-Thr-Lys-Pro-Tyr-His Thr-Thr-Lys-Pro-Tyr-His 652 Thr-Thr-Lys-Pro-Tyr-Pro Thr-Thr-Lys-Pro-Tyr-Pro Thr-Thr-Lys-Pro-Tyr-Pro 653 Thr-Thr-Lys-Pro-Tyr-Lys Thr-Thr-Lys-Pro-Tyr-Lys Thr-Thr-Lys-Pro-Tyr-Lys 654 Thr-Thr-Lys-Pro-Arg Thr-Thr-Lys-Pro-Arg Thr-Thr-Lys-Pro-Arg 655 Thr-Thr-Lys-Pro-Arg-Arg Thr-Thr-Lys-Pro-Arg-Arg Thr-Thr-Lys-Pro-Arg-Arg 656 Thr-Thr-Lys-Pro-Arg-Phe Thr-Thr-Lys-Pro-Arg-Phe Thr-Thr-Lys-Pro-Arg-Phe 657 Thr-Thr-Lys-Pro-Arg-Tyr Thr-Thr-Lys-Pro-Arg-Tyr Thr-Thr-Lys-Pro-Arg-Tyr 658 Thr-Thr-Lys-Pro-Arg-His Thr-Thr-Lys-Pro-Arg-His Thr-Thr-Lys-Pro-Arg-His 659 Thr-Thr-Lys-Pro-Arg-Pro Thr-Thr-Lys-Pro-Arg-Pro Thr-Thr-Lys-Pro-Arg-Pro 660 Thr-Thr-Lys-Pro-Arg-Lys Thr-Thr-Lys-Pro-Arg-Lys Thr-Thr-Lys-Pro-Arg-Lys 661 Ala-Thr-Lys-Pro-Arg Ala-Thr-Lys-Pro-Arg Ala-Thr-Lys-Pro-Arg 662 Ala-Thr-Lys-Pro-Phe Ala-Thr-Lys-Pro-Phe Ala-Thr-Lys-Pro-Phe 663 Ala-Thr-Lys-Pro-Tyr Ala-Thr-Lys-Pro-Tyr Ala-Thr-Lys-Pro-Tyr 664 Ala-Thr-Lys-Pro-Gly Ala-Thr-Lys-Pro-Gly Ala-Thr-Lys-Pro-Gly 665 Ala-Thr-Lys-Pro-His Ala-Thr-Lys-Pro-His Ala-Thr-Lys-Pro-His 666 Ala-Thr-Lys-Pro-Lys Ala-Thr-Lys-Pro-Lys Ala-Thr-Lys-Pro-Lys 667 Ala-Thr-Lys-Pro-Gly Ala-Thr-Lys-Pro-Gly Ala-Thr-Lys-Pro-Gly 668 Ala-Thr-Lys-Pro-Gly-Arg Ala-Thr-Lys-Pro-Gly-Arg Ala-Thr-Lys-Pro-Gly-Arg 669 Ala-Thr-Lys-Pro-Gly-Phe Ala-Thr-Lys-Pro-Gly-Phe Ala-Thr-Lys-Pro-Gly-Phe 670 Ala-Thr-Lys-Pro-Gly-Tyr Ala-Thr-Lys-Pro-Gly-Tyr Ala-Thr-Lys-Pro-Gly-Tyr 671 Ala-Thr-Lys-Pro-Gly-His Ala-Thr-Lys-Pro-Gly-His Ala-Thr-Lys-Pro-Gly-His 672 Ala-Thr-Lys-Pro-Gly-Pro Ala-Thr-Lys-Pro-Gly-Pro Ala-Thr-Lys-Pro-Gly-Pro 673 Ala-Thr-Lys-Pro-Gly-Lys Ala-Thr-Lys-Pro-Gly-Lys Ala-Thr-Lys-Pro-Gly-Lys 674 Ala-Thr-Lys-Pro-Asp Ala-Thr-Lys-Pro-Asp Ala-Thr-Lys-Pro-Asp 675 Ala-Thr-Lys-Pro-Asp-Arg Ala-Thr-Lys-Pro-Asp-Arg Ala-Thr-Lys-Pro-Asp-Arg 676 Ala-Thr-Lys-Pro-Asp-Phe Ala-Thr-Lys-Pro-Asp-Phe Ala-Thr-Lys-Pro-Asp-Phe 677 Ala-Thr-Lys-Pro-Asp-Tyr Ala-Thr-Lys-Pro-Asp-Tyr Ala-Thr-Lys-Pro-Asp-Tyr 678 Ala-Thr-Lys-Pro-Asp-His Ala-Thr-Lys-Pro-Asp-His Ala-Thr-Lys-Pro-Asp-His 679 Ala-Thr-Lys-Pro-Asp-Pro Ala-Thr-Lys-Pro-Asp-Pro Ala-Thr-Lys-Pro-Asp-Pro 680 Ala-Thr-Lys-Pro-Asp-Lys Ala-Thr-Lys-Pro-Asp-Lys Ala-Thr-Lys-Pro-Asp-Lys 681 Ala-Thr-Lys-Pro-Trp Ala-Thr-Lys-Pro-Trp Ala-Thr-Lys-Pro-Trp 682 Ala-Thr-Lys-Pro-Trp-Arg Ala-Thr-Lys-Pro-Trp-Arg Ala-Thr-Lys-Pro-Trp-Arg 683 Ala-Thr-Lys-Pro-Trp-Phe Ala-Thr-Lys-Pro-Trp-Phe Ala-Thr-Lys-Pro-Trp-Phe 684 Ala-Thr-Lys-Pro-Trp-Tyr Ala-Thr-Lys-Pro-Trp-Tyr Ala-Thr-Lys-Pro-Trp-Tyr 685 Ala-Thr-Lys-Pro-Trp-His Ala-Thr-Lys-Pro-Trp-His Ala-Thr-Lys-Pro-Trp-His 686 Ala-Thr-Lys-Pro-Trp-Pro Ala-Thr-Lys-Pro-Trp-Pro Ala-Thr-Lys-Pro-Trp-Pro 687 Ala-Thr-Lys-Pro-Trp-Lys Ala-Thr-Lys-Pro-Trp-Lys Ala-Thr-Lys-Pro-Trp-Lys 688 Ala-Thr-Lys-Pro-Gln Ala-Thr-Lys-Pro-Gln Ala-Thr-Lys-Pro-Gln 689 Ala-Thr-Lys-Pro-Gln-Arg Ala-Thr-Lys-Pro-Gln-Arg Ala-Thr-Lys-Pro-Gln-Arg 690 Ala-Thr-Lys-Pro-Gln-Phe Ala-Thr-Lys-Pro-Gln-Phe Ala-Thr-Lys-Pro-Gln-Phe 691 Ala-Thr-Lys-Pro-Gln-Tyr Ala-Thr-Lys-Pro-Gln-Tyr Ala-Thr-Lys-Pro-Gln-Tyr 692 Ala-Thr-Lys-Pro-Gln-His Ala-Thr-Lys-Pro-Gln-His Ala-Thr-Lys-Pro-Gln-His 693 Ala-Thr-Lys-Pro-Gln-Pro Ala-Thr-Lys-Pro-Gln-Pro Ala-Thr-Lys-Pro-Gln-Pro 694 Ala-Thr-Lys-Pro-Gln-Lys Ala-Thr-Lys-Pro-Gln-Lys Ala-Thr-Lys-Pro-Gln-Lys 695 Ala-Thr-Lys-Pro-Asn Ala-Thr-Lys-Pro-Asn Ala-Thr-Lys-Pro-Asn 696 Ala-Thr-Lys-Pro-Asn-Arg Ala-Thr-Lys-Pro-Asn-Arg Ala-Thr-Lys-Pro-Asn-Arg 697 Ala-Thr-Lys-Pro-Asn-Phe Ala-Thr-Lys-Pro-Asn-Phe Ala-Thr-Lys-Pro-Asn-Phe 698 Ala-Thr-Lys-Pro-Asn-Tyr Ala-Thr-Lys-Pro-Asn-Tyr Ala-Thr-Lys-Pro-Asn-Tyr 699 Ala-Thr-Lys-Pro-Asn-His Ala-Thr-Lys-Pro-Asn-His Ala-Thr-Lys-Pro-Asn-His 700 Ala-Thr-Lys-Pro-Asn-Pro Ala-Thr-Lys-Pro-Asn-Pro Ala-Thr-Lys-Pro-Asn-Pro 701 Ala-Thr-Lys-Pro-Asn-Lys Ala-Thr-Lys-Pro-Asn-Lys Ala-Thr-Lys-Pro-Asn-Lys 702 Ala-Thr-Lys-Pro-Tyr Ala-Thr-Lys-Pro-Tyr Ala-Thr-Lys-Pro-Tyr 703 Ala-Thr-Lys-Pro-Tyr-Arg Ala-Thr-Lys-Pro-Tyr-Arg Ala-Thr-Lys-Pro-Tyr-Arg 704 Ala-Thr-Lys-Pro-Tyr-Phe Ala-Thr-Lys-Pro-Tyr-Phe Ala-Thr-Lys-Pro-Tyr-Phe 705

Ala-Thr-Lys-Pro-Tyr-Tyr Ala-Thr-Lys-Pro-Tyr-Tyr Ala-Thr-Lys-Pro-Tyr-Tyr 706 Ala-Thr-Lys-Pro-Tyr-His Ala-Thr-Lys-Pro-Tyr-His Ala-Thr-Lys-Pro-Tyr-His 707 Ala-Thr-Lys-Pro-Tyr-Pro Ala-Thr-Lys-Pro-Tyr-Pro Ala-Thr-Lys-Pro-Tyr-Pro 708 Ala-Thr-Lys-Pro-Tyr-Lys Ala-Thr-Lys-Pro-Tyr-Lys Ala-Thr-Lys-Pro-Tyr-Lys 709 Ala-Thr-Lys-Pro-Arg Ala-Thr-Lys-Pro-Arg Ala-Thr-Lys-Pro-Arg 710 Ala-Thr-Lys-Pro-Arg-Arg Ala-Thr-Lys-Pro-Arg-Arg Ala-Thr-Lys-Pro-Arg-Arg 711 Ala-Thr-Lys-Pro-Arg-Phe Ala-Thr-Lys-Pro-Arg-Phe Ala-Thr-Lys-Pro-Arg-Phe 712 Ala-Thr-Lys-Pro-Arg-Tyr Ala-Thr-Lys-Pro-Arg-Tyr Ala-Thr-Lys-Pro-Arg-Tyr 713 Ala-Thr-Lys-Pro-Arg-His Ala-Thr-Lys-Pro-Arg-His Ala-Thr-Lys-Pro-Arg-His 714 Ala-Thr-Lys-Pro-Arg-Pro Ala-Thr-Lys-Pro-Arg-Pro Ala-Thr-Lys-Pro-Arg-Pro 715 Ala-Thr-Lys-Pro-Arg-Lys Ala-Thr-Lys-Pro-Arg-Lys Ala-Thr-Lys-Pro-Arg-Lys 716 His-Thr-Lys-Pro-Arg His-Thr-Lys-Pro-Arg His-Thr-Lys-Pro-Arg 717 His-Thr-Lys-Pro-Phe His-Thr-Lys-Pro-Phe His-Thr-Lys-Pro-Phe 718 His-Thr-Lys-Pro-Tyr His-Thr-Lys-Pro-Tyr His-Thr-Lys-Pro-Tyr 719 His-Thr-Lys-Pro-Gly His-Thr-Lys-Pro-Gly His-Thr-Lys-Pro-Gly 720 His-Thr-Lys-Pro-His His-Thr-Lys-Pro-His His-Thr-Lys-Pro-His 721 His-Thr-Lys-Pro-Lys His-Thr-Lys-Pro-Lys His-Thr-Lys-Pro-Lys 722 His-Thr-Lys-Pro-Gly His-Thr-Lys-Pro-Gly His-Thr-Lys-Pro-Gly 723 His-Thr-Lys-Pro-Gly-Arg His-Thr-Lys-Pro-Gly-Arg His-Thr-Lys-Pro-Gly-Arg 724 His-Thr-Lys-Pro-Gly-Phe His-Thr-Lys-Pro-Gly-Phe His-Thr-Lys-Pro-Gly-Phe 725 His-Thr-Lys-Pro-Gly-Tyr His-Thr-Lys-Pro-Gly-Tyr His-Thr-Lys-Pro-Gly-Tyr 726 His-Thr-Lys-Pro-Gly-His His-Thr-Lys-Pro-Gly-His His-Thr-Lys-Pro-Gly-His 727 His-Thr-Lys-Pro-Gly-Pro His-Thr-Lys-Pro-Gly-Pro His-Thr-Lys-Pro-Gly-Pro 728 His-Thr-Lys-Pro-Gly-Lys His-Thr-Lys-Pro-Gly-Lys His-Thr-Lys-Pro-Gly-Lys 729 His-Thr-Lys-Pro-Asp His-Thr-Lys-Pro-Asp His-Thr-Lys-Pro-Asp 730 His-Thr-Lys-Pro-Asp-Arg His-Thr-Lys-Pro-Asp-Arg His-Thr-Lys-Pro-Asp-Arg 731 His-Thr-Lys-Pro-Asp-Phe His-Thr-Lys-Pro-Asp-Phe His-Thr-Lys-Pro-Asp-Phe 732 His-Thr-Lys-Pro-Asp-Tyr His-Thr-Lys-Pro-Asp-Tyr His-Thr-Lys-Pro-Asp-Tyr 733 His-Thr-Lys-Pro-Asp-His His-Thr-Lys-Pro-Asp-His His-Thr-Lys-Pro-Asp-His 734 His-Thr-Lys-Pro-Asp-Pro His-Thr-Lys-Pro-Asp-Pro His-Thr-Lys-Pro-Asp-Pro 735 His-Thr-Lys-Pro-Asp-Lys His-Thr-Lys-Pro-Asp-Lys His-Thr-Lys-Pro-Asp-Lys 736 His-Thr-Lys-Pro-Trp His-Thr-Lys-Pro-Trp His-Thr-Lys-Pro-Trp 737 His-Thr-Lys-Pro-Trp-Arg His-Thr-Lys-Pro-Trp-Arg His-Thr-Lys-Pro-Trp-Arg 738 His-Thr-Lys-Pro-Trp-Phe His-Thr-Lys-Pro-Trp-Phe His-Thr-Lys-Pro-Trp-Phe 739 His-Thr-Lys-Pro-Trp-Tyr His-Thr-Lys-Pro-Trp-Tyr His-Thr-Lys-Pro-Trp-Tyr 740 His-Thr-Lys-Pro-Trp-His His-Thr-Lys-Pro-Trp-His His-Thr-Lys-Pro-Trp-His 741 His-Thr-Lys-Pro-Trp-Pro His-Thr-Lys-Pro-Trp-Pro His-Thr-Lys-Pro-Trp-Pro 742 His-Thr-Lys-Pro-Trp-Lys His-Thr-Lys-Pro-Trp-Lys His-Thr-Lys-Pro-Trp-Lys 743 His-Thr-Lys-Pro-Gln His-Thr-Lys-Pro-Gln His-Thr-Lys-Pro-Gln 744 His-Thr-Lys-Pro-Gln-Arg His-Thr-Lys-Pro-Gln-Arg His-Thr-Lys-Pro-Gln-Arg 745 His-Thr-Lys-Pro-Gln-Phe His-Thr-Lys-Pro-Gln-Phe His-Thr-Lys-Pro-Gln-Phe 746 His-Thr-Lys-Pro-Gln-Tyr His-Thr-Lys-Pro-Gln-Tyr His-Thr-Lys-Pro-Gln-Tyr 747 His-Thr-Lys-Pro-Gln-His His-Thr-Lys-Pro-Gln-His His-Thr-Lys-Pro-Gln-His 748 His-Thr-Lys-Pro-Gln-Pro His-Thr-Lys-Pro-Gln-Pro His-Thr-Lys-Pro-Gln-Pro 749 His-Thr-Lys-Pro-Gln-Lys His-Thr-Lys-Pro-Gln-Lys His-Thr-Lys-Pro-Gln-Lys 750 His-Thr-Lys-Pro-Asn His-Thr-Lys-Pro-Asn His-Thr-Lys-Pro-Asn 751 His-Thr-Lys-Pro-Asn-Arg His-Thr-Lys-Pro-Asn-Arg His-Thr-Lys-Pro-Asn-Arg 752 His-Thr-Lys-Pro-Asn-Phe His-Thr-Lys-Pro-Asn-Phe His-Thr-Lys-Pro-Asn-Phe 753 His-Thr-Lys-Pro-Asn-Tyr His-Thr-Lys-Pro-Asn-Tyr His-Thr-Lys-Pro-Asn-Tyr 754 His-Thr-Lys-Pro-Asn-His His-Thr-Lys-Pro-Asn-His His-Thr-Lys-Pro-Asn-His 755 His-Thr-Lys-Pro-Asn-Pro His-Thr-Lys-Pro-Asn-Pro His-Thr-Lys-Pro-Asn-Pro 756 His-Thr-Lys-Pro-Asn-Lys His-Thr-Lys-Pro-Asn-Lys His-Thr-Lys-Pro-Asn-Lys 757 His-Thr-Lys-Pro-Tyr His-Thr-Lys-Pro-Tyr His-Thr-Lys-Pro-Tyr 758 His-Thr-Lys-Pro-Tyr-Arg His-Thr-Lys-Pro-Tyr-Arg His-Thr-Lys-Pro-Tyr-Arg 759 His-Thr-Lys-Pro-Tyr-Phe His-Thr-Lys-Pro-Tyr-Phe His-Thr-Lys-Pro-Tyr-Phe 760 His-Thr-Lys-Pro-Tyr-Tyr His-Thr-Lys-Pro-Tyr-Tyr His-Thr-Lys-Pro-Tyr-Tyr 761 His-Thr-Lys-Pro-Tyr-His His-Thr-Lys-Pro-Tyr-His His-Thr-Lys-Pro-Tyr-His 762 His-Thr-Lys-Pro-Tyr-Pro His-Thr-Lys-Pro-Tyr-Pro His-Thr-Lys-Pro-Tyr-Pro 763 His-Thr-Lys-Pro-Tyr-Lys His-Thr-Lys-Pro-Tyr-Lys His-Thr-Lys-Pro-Tyr-Lys 764 His-Thr-Lys-Pro-Arg His-Thr-Lys-Pro-Arg His-Thr-Lys-Pro-Arg 765 His-Thr-Lys-Pro-Arg-Arg His-Thr-Lys-Pro-Arg-Arg His-Thr-Lys-Pro-Arg-Arg 766 His-Thr-Lys-Pro-Arg-Phe His-Thr-Lys-Pro-Arg-Phe His-Thr-Lys-Pro-Arg-Phe 767 His-Thr-Lys-Pro-Arg-Tyr His-Thr-Lys-Pro-Arg-Tyr His-Thr-Lys-Pro-Arg-Tyr 768 His-Thr-Lys-Pro-Arg-His His-Thr-Lys-Pro-Arg-His His-Thr-Lys-Pro-Arg-His 769 His-Thr-Lys-Pro-Arg-Pro His-Thr-Lys-Pro-Arg-Pro His-Thr-Lys-Pro-Arg-Pro 770 His-Thr-Lys-Pro-Arg-Lys His-Thr-Lys-Pro-Arg-Lys His-Thr-Lys-Pro-Arg-Lys 771 Lys-Thr-Lys-Pro-Arg Lys-Thr-Lys-Pro-Arg Lys-Thr-Lys-Pro-Arg 772 Lys-Thr-Lys-Pro-Phe Lys-Thr-Lys-Pro-Phe Lys-Thr-Lys-Pro-Phe 773 Lys-Thr-Lys-Pro-Tyr Lys-Thr-Lys-Pro-Tyr Lys-Thr-Lys-Pro-Tyr 774 Lys-Thr-Lys-Pro-Gly Lys-Thr-Lys-Pro-Gly Lys-Thr-Lys-Pro-Gly 775 Lys-Thr-Lys-Pro-His Lys-Thr-Lys-Pro-His Lys-Thr-Lys-Pro-His 776 Lys-Thr-Lys-Pro-Lys Lys-Thr-Lys-Pro-Lys Lys-Thr-Lys-Pro-Lys 777 Lys-Thr-Lys-Pro-Gly Lys-Thr-Lys-Pro-Gly Lys-Thr-Lys-Pro-Gly 778 Lys-Thr-Lys-Pro-Gly-Arg Lys-Thr-Lys-Pro-Gly-Arg Lys-Thr-Lys-Pro-Gly-Arg 779 Lys-Thr-Lys-Pro-Gly-Phe Lys-Thr-Lys-Pro-Gly-Phe Lys-Thr-Lys-Pro-Gly-Phe 780 Lys-Thr-Lys-Pro-Gly-Tyr Lys-Thr-Lys-Pro-Gly-Tyr Lys-Thr-Lys-Pro-Gly-Tyr 781 Lys-Thr-Lys-Pro-Gly-His Lys-Thr-Lys-Pro-Gly-His Lys-Thr-Lys-Pro-Gly-His 782 Lys-Thr-Lys-Pro-Gly-Pro Lys-Thr-Lys-Pro-Gly-Pro Lys-Thr-Lys-Pro-Gly-Pro 783 Lys-Thr-Lys-Pro-Gly-Lys Lys-Thr-Lys-Pro-Gly-Lys Lys-Thr-Lys-Pro-Gly-Lys 784 Lys-Thr-Lys-Pro-Asp Lys-Thr-Lys-Pro-Asp Lys-Thr-Lys-Pro-Asp 785 Lys-Thr-Lys-Pro-Asp-Arg Lys-Thr-Lys-Pro-Asp-Arg Lys-Thr-Lys-Pro-Asp-Arg 786 Lys-Thr-Lys-Pro-Asp-Phe Lys-Thr-Lys-Pro-Asp-Phe Lys-Thr-Lys-Pro-Asp-Phe 787 Lys-Thr-Lys-Pro-Asp-Tyr Lys-Thr-Lys-Pro-Asp-Tyr Lys-Thr-Lys-Pro-Asp-Tyr 788 Lys-Thr-Lys-Pro-Asp-His Lys-Thr-Lys-Pro-Asp-His Lys-Thr-Lys-Pro-Asp-His 789 Lys-Thr-Lys-Pro-Asp-Pro Lys-Thr-Lys-Pro-Asp-Pro Lys-Thr-Lys-Pro-Asp-Pro 790 Lys-Thr-Lys-Pro-Asp-Lys Lys-Thr-Lys-Pro-Asp-Lys Lys-Thr-Lys-Pro-Asp-Lys 791 Lys-Thr-Lys-Pro-Trp Lys-Thr-Lys-Pro-Trp Lys-Thr-Lys-Pro-Trp 792 Lys-Thr-Lys-Pro-Trp-Arg Lys-Thr-Lys-Pro-Trp-Arg Lys-Thr-Lys-Pro-Trp-Arg 793 Lys-Thr-Lys-Pro-Trp-Phe Lys-Thr-Lys-Pro-Trp-Phe Lys-Thr-Lys-Pro-Trp-Phe 794 Lys-Thr-Lys-Pro-Trp-Tyr Lys-Thr-Lys-Pro-Trp-Tyr Lys-Thr-Lys-Pro-Trp-Tyr 795 Lys-Thr-Lys-Pro-Trp-His Lys-Thr-Lys-Pro-Trp-His Lys-Thr-Lys-Pro-Trp-His 796

Lys-Thr-Lys-Pro-Trp-Pro Lys-Thr-Lys-Pro-Trp-Pro Lys-Thr-Lys-Pro-Trp-Pro 797 Lys-Thr-Lys-Pro-Trp-Lys Lys-Thr-Lys-Pro-Trp-Lys Lys-Thr-Lys-Pro-Trp-Lys 798 Lys-Thr-Lys-Pro-Gln Lys-Thr-Lys-Pro-Gln Lys-Thr-Lys-Pro-Gln 799 Lys-Thr-Lys-Pro-Gln-Arg Lys-Thr-Lys-Pro-Gln-Arg Lys-Thr-Lys-Pro-Gln-Arg 800 Lys-Thr-Lys-Pro-Gln-Phe Lys-Thr-Lys-Pro-Gln-Phe Lys-Thr-Lys-Pro-Gln-Phe 801 Lys-Thr-Lys-Pro-Gln-Tyr Lys-Thr-Lys-Pro-Gln-Tyr Lys-Thr-Lys-Pro-Gln-Tyr 802 Lys-Thr-Lys-Pro-Gln-His Lys-Thr-Lys-Pro-Gln-His Lys-Thr-Lys-Pro-Gln-His 803 Lys-Thr-Lys-Pro-Gln-Pro Lys-Thr-Lys-Pro-Gln-Pro Lys-Thr-Lys-Pro-Gln-Pro 804 Lys-Thr-Lys-Pro-Gln-Lys Lys-Thr-Lys-Pro-Gln-Lys Lys-Thr-Lys-Pro-Gln-Lys 805 Lys-Thr-Lys-Pro-Asn Lys-Thr-Lys-Pro-Asn Lys-Thr-Lys-Pro-Asn 806 Lys-Thr-Lys-Pro-Asn-Arg Lys-Thr-Lys-Pro-Asn-Arg Lys-Thr-Lys-Pro-Asn-Arg 807 Lys-Thr-Lys-Pro-Asn-Phe Lys-Thr-Lys-Pro-Asn-Phe Lys-Thr-Lys-Pro-Asn-Phe 808 Lys-Thr-Lys-Pro-Asn-Tyr Lys-Thr-Lys-Pro-Asn-Tyr Lys-Thr-Lys-Pro-Asn-Tyr 809 Lys-Thr-Lys-Pro-Asn-His Lys-Thr-Lys-Pro-Asn-His Lys-Thr-Lys-Pro-Asn-His 810 Lys-Thr-Lys-Pro-Asn-Pro Lys-Thr-Lys-Pro-Asn-Pro Lys-Thr-Lys-Pro-Asn-Pro 811 Lys-Thr-Lys-Pro-Asn-Lys Lys-Thr-Lys-Pro-Asn-Lys Lys-Thr-Lys-Pro-Asn-Lys 812 Lys-Thr-Lys-Pro-Tyr Lys-Thr-Lys-Pro-Tyr Lys-Thr-Lys-Pro-Tyr 813 Lys-Thr-Lys-Pro-Tyr-Arg Lys-Thr-Lys-Pro-Tyr-Arg Lys-Thr-Lys-Pro-Tyr-Arg 814 Lys-Thr-Lys-Pro-Tyr-Phe Lys-Thr-Lys-Pro-Tyr-Phe Lys-Thr-Lys-Pro-Tyr-Phe 815 Lys-Thr-Lys-Pro-Tyr-Tyr Lys-Thr-Lys-Pro-Tyr-Tyr Lys-Thr-Lys-Pro-Tyr-Tyr 816 Lys-Thr-Lys-Pro-Tyr-His Lys-Thr-Lys-Pro-Tyr-His Lys-Thr-Lys-Pro-Tyr-His 817 Lys-Thr-Lys-Pro-Tyr-Pro Lys-Thr-Lys-Pro-Tyr-Pro Lys-Thr-Lys-Pro-Tyr-Pro 818 Lys-Thr-Lys-Pro-Tyr-Lys Lys-Thr-Lys-Pro-Tyr-Lys Lys-Thr-Lys-Pro-Tyr-Lys 819 Lys-Thr-Lys-Pro-Arg Lys-Thr-Lys-Pro-Arg Lys-Thr-Lys-Pro-Arg 820 Lys-Thr-Lys-Pro-Arg-Arg Lys-Thr-Lys-Pro-Arg-Arg Lys-Thr-Lys-Pro-Arg-Arg 821 Lys-Thr-Lys-Pro-Arg-Phe Lys-Thr-Lys-Pro-Arg-Phe Lys-Thr-Lys-Pro-Arg-Phe 822 Lys-Thr-Lys-Pro-Arg-Tyr Lys-Thr-Lys-Pro-Arg-Tyr Lys-Thr-Lys-Pro-Arg-Tyr 823 Lys-Thr-Lys-Pro-Arg-His Lys-Thr-Lys-Pro-Arg-His Lys-Thr-Lys-Pro-Arg-His 824 Lys-Thr-Lys-Pro-Arg-Pro Lys-Thr-Lys-Pro-Arg-Pro Lys-Thr-Lys-Pro-Arg-Pro 825 Lys-Thr-Lys-Pro-Arg-Lys Lys-Thr-Lys-Pro-Arg-Lys Lys-Thr-Lys-Pro-Arg-Lys 826 Gly-Thr-Lys-Pro-Arg Gly-Thr-Lys-Pro-Arg Gly-Thr-Lys-Pro-Arg 827 Gly-Thr-Lys-Pro-Phe Gly-Thr-Lys-Pro-Phe Gly-Thr-Lys-Pro-Phe 828 Gly-Thr-Lys-Pro-Tyr Gly-Thr-Lys-Pro-Tyr Gly-Thr-Lys-Pro-Tyr 829 Gly-Thr-Lys-Pro-Gly Gly-Thr-Lys-Pro-Gly Gly-Thr-Lys-Pro-Gly 830 Gly-Thr-Lys-Pro-His Gly-Thr-Lys-Pro-His Gly-Thr-Lys-Pro-His 831 Gly-Thr-Lys-Pro-Lys Gly-Thr-Lys-Pro-Lys Gly-Thr-Lys-Pro-Lys 832 Gly-Thr-Lys-Pro-Gly Gly-Thr-Lys-Pro-Gly Gly-Thr-Lys-Pro-Gly 833 Gly-Thr-Lys-Pro-Gly-Arg Gly-Thr-Lys-Pro-Gly-Arg Gly-Thr-Lys-Pro-Gly-Arg 834 Gly-Thr-Lys-Pro-Gly-Phe Gly-Thr-Lys-Pro-Gly-Phe Gly-Thr-Lys-Pro-Gly-Phe 835 Gly-Thr-Lys-Pro-Gly-Tyr Gly-Thr-Lys-Pro-Gly-Tyr Gly-Thr-Lys-Pro-Gly-Tyr 836 Gly-Thr-Lys-Pro-Gly-His Gly-Thr-Lys-Pro-Gly-His Gly-Thr-Lys-Pro-Gly-His 837 Gly-Thr-Lys-Pro-Gly-Pro Gly-Thr-Lys-Pro-Gly-Pro Gly-Thr-Lys-Pro-Gly-Pro 838 Gly-Thr-Lys-Pro-Gly-Lys Gly-Thr-Lys-Pro-Gly-Lys Gly-Thr-Lys-Pro-Gly-Lys 839 Gly-Thr-Lys-Pro-Asp Gly-Thr-Lys-Pro-Asp Gly-Thr-Lys-Pro-Asp 840 Gly-Thr-Lys-Pro-Asp-Arg Gly-Thr-Lys-Pro-Asp-Arg Gly-Thr-Lys-Pro-Asp-Arg 841 Gly-Thr-Lys-Pro-Asp-Phe Gly-Thr-Lys-Pro-Asp-Phe Gly-Thr-Lys-Pro-Asp-Phe 842 Gly-Thr-Lys-Pro-Asp-Tyr Gly-Thr-Lys-Pro-Asp-Tyr Gly-Thr-Lys-Pro-Asp-Tyr 843 Gly-Thr-Lys-Pro-Asp-His Gly-Thr-Lys-Pro-Asp-His Gly-Thr-Lys-Pro-Asp-His 844 Gly-Thr-Lys-Pro-Asp-Pro Gly-Thr-Lys-Pro-Asp-Pro Gly-Thr-Lys-Pro-Asp-Pro 845 Gly-Thr-Lys-Pro-Asp-Lys Gly-Thr-Lys-Pro-Asp-Lys Gly-Thr-Lys-Pro-Asp-Lys 846 Gly-Thr-Lys-Pro-Trp Gly-Thr-Lys-Pro-Trp Gly-Thr-Lys-Pro-Trp 847 Gly-Thr-Lys-Pro-Trp-Arg Gly-Thr-Lys-Pro-Trp-Arg Gly-Thr-Lys-Pro-Trp-Arg 848 Gly-Thr-Lys-Pro-Trp-Phe Gly-Thr-Lys-Pro-Trp-Phe Gly-Thr-Lys-Pro-Trp-Phe 849 Gly-Thr-Lys-Pro-Trp-Tyr Gly-Thr-Lys-Pro-Trp-Tyr Gly-Thr-Lys-Pro-Trp-Tyr 850 Gly-Thr-Lys-Pro-Trp-His Gly-Thr-Lys-Pro-Trp-His Gly-Thr-Lys-Pro-Trp-His 851 Gly-Thr-Lys-Pro-Trp-Pro Gly-Thr-Lys-Pro-Trp-Pro Gly-Thr-Lys-Pro-Trp-Pro 852 Gly-Thr-Lys-Pro-Trp-Lys Gly-Thr-Lys-Pro-Trp-Lys Gly-Thr-Lys-Pro-Trp-Lys 853 Gly-Thr-Lys-Pro-Gln Gly-Thr-Lys-Pro-Gln Gly-Thr-Lys-Pro-Gln 854 Gly-Thr-Lys-Pro-Gln-Arg Gly-Thr-Lys-Pro-Gln-Arg Gly-Thr-Lys-Pro-Gln-Arg 855 Gly-Thr-Lys-Pro-Gln-Phe Gly-Thr-Lys-Pro-Gln-Phe Gly-Thr-Lys-Pro-Gln-Phe 856 Gly-Thr-Lys-Pro-Gln-Tyr Gly-Thr-Lys-Pro-Gln-Tyr Gly-Thr-Lys-Pro-Gln-Tyr 857 Gly-Thr-Lys-Pro-Gln-His Gly-Thr-Lys-Pro-Gln-His Gly-Thr-Lys-Pro-Gln-His 858 Gly-Thr-Lys-Pro-Gln-Pro Gly-Thr-Lys-Pro-Gln-Pro Gly-Thr-Lys-Pro-Gln-Pro 859 Gly-Thr-Lys-Pro-Gln-Lys Gly-Thr-Lys-Pro-Gln-Lys Gly-Thr-Lys-Pro-Gln-Lys 860 Gly-Thr-Lys-Pro-Asn Gly-Thr-Lys-Pro-Asn Gly-Thr-Lys-Pro-Asn 861 Gly-Thr-Lys-Pro-Asn-Arg Gly-Thr-Lys-Pro-Asn-Arg Gly-Thr-Lys-Pro-Asn-Arg 862 Gly-Thr-Lys-Pro-Asn-Phe Gly-Thr-Lys-Pro-Asn-Phe Gly-Thr-Lys-Pro-Asn-Phe 863 Gly-Thr-Lys-Pro-Asn-Tyr Gly-Thr-Lys-Pro-Asn-Tyr Gly-Thr-Lys-Pro-Asn-Tyr 864 Gly-Thr-Lys-Pro-Asn-His Gly-Thr-Lys-Pro-Asn-His Gly-Thr-Lys-Pro-Asn-His 865 Gly-Thr-Lys-Pro-Asn-Pro Gly-Thr-Lys-Pro-Asn-Pro Gly-Thr-Lys-Pro-Asn-Pro 866 Gly-Thr-Lys-Pro-Asn-Lys Gly-Thr-Lys-Pro-Asn-Lys Gly-Thr-Lys-Pro-Asn-Lys 867 Gly-Thr-Lys-Pro-Tyr Gly-Thr-Lys-Pro-Tyr Gly-Thr-Lys-Pro-Tyr 868 Gly-Thr-Lys-Pro-Tyr-Arg Gly-Thr-Lys-Pro-Tyr-Arg Gly-Thr-Lys-Pro-Tyr-Arg 869 Gly-Thr-Lys-Pro-Tyr-Phe Gly-Thr-Lys-Pro-Tyr-Phe Gly-Thr-Lys-Pro-Tyr-Phe 870 Gly-Thr-Lys-Pro-Tyr-Tyr Gly-Thr-Lys-Pro-Tyr-Tyr Gly-Thr-Lys-Pro-Tyr-Tyr 871 Gly-Thr-Lys-Pro-Tyr-His Gly-Thr-Lys-Pro-Tyr-His Gly-Thr-Lys-Pro-Tyr-His 872 Gly-Thr-Lys-Pro-Tyr-Pro Gly-Thr-Lys-Pro-Tyr-Pro Gly-Thr-Lys-Pro-Tyr-Pro 873 Gly-Thr-Lys-Pro-Tyr-Lys Gly-Thr-Lys-Pro-Tyr-Lys Gly-Thr-Lys-Pro-Tyr-Lys 874 Gly-Thr-Lys-Pro-Arg Gly-Thr-Lys-Pro-Arg Gly-Thr-Lys-Pro-Arg 875 Gly-Thr-Lys-Pro-Arg-Arg Gly-Thr-Lys-Pro-Arg-Arg Gly-Thr-Lys-Pro-Arg-Arg 876 Gly-Thr-Lys-Pro-Arg-Phe Gly-Thr-Lys-Pro-Arg-Phe Gly-Thr-Lys-Pro-Arg-Phe 877 Gly-Thr-Lys-Pro-Arg-Tyr Gly-Thr-Lys-Pro-Arg-Tyr Gly-Thr-Lys-Pro-Arg-Tyr 878 Gly-Thr-Lys-Pro-Arg-His Gly-Thr-Lys-Pro-Arg-His Gly-Thr-Lys-Pro-Arg-His 879 Gly-Thr-Lys-Pro-Arg-Pro Gly-Thr-Lys-Pro-Arg-Pro Gly-Thr-Lys-Pro-Arg-Pro 880 Gly-Thr-Lys-Pro-Arg-Lys Gly-Thr-Lys-Pro-Arg-Lys Gly-Thr-Lys-Pro-Arg-Lys 881 Thr-Lys-Pro-Arg-Val Thr-Lys-Pro-Arg-Val Thr-Lys-Pro-Arg-Val 882 Thr-Lys-Pro-Phe-Val Thr-Lys-Pro-Phe-Val Thr-Lys-Pro-Phe-Val 883 Thr-Lys-Pro-Tyr-Val Thr-Lys-Pro-Tyr-Val Thr-Lys-Pro-Tyr-Val 884 Thr-Lys-Pro-Gly-Val Thr-Lys-Pro-Gly-Val Thr-Lys-Pro-Gly-Val 885 Thr-Lys-Pro-His-Val Thr-Lys-Pro-His-Val Thr-Lys-Pro-His-Val 886 Thr-Lys-Pro-Lys-Val Thr-Lys-Pro-Lys-Val Thr-Lys-Pro-Lys-Val 887 Thr-Lys-Pro-Gly-Val Thr-Lys-Pro-Gly-Val Thr-Lys-Pro-Gly-Val 888

Thr-Lys-Pro-Gly-Arg-Val Thr-Lys-Pro-Gly-Arg-Val Thr-Lys-Pro-Gly-Arg-Val 889 Thr-Lys-Pro-Gly-Phe-Val Thr-Lys-Pro-Gly-Phe-Val Thr-Lys-Pro-Gly-Phe-Val 890 Thr-Lys-Pro-Gly-Tyr-Val Thr-Lys-Pro-Gly-Tyr-Val Thr-Lys-Pro-Gly-Tyr-Val 891 Thr-Lys-Pro-Gly-His-Val Thr-Lys-Pro-Gly-His-Val Thr-Lys-Pro-Gly-His-Val 892 Thr-Lys-Pro-Gly-Pro-Val Thr-Lys-Pro-Gly-Pro-Val Thr-Lys-Pro-Gly-Pro-Val 893 Thr-Lys-Pro-Gly-Lys-Val Thr-Lys-Pro-Gly-Lys-Val Thr-Lys-Pro-Gly-Lys-Val 894 Thr-Lys-Pro-Asp-Val Thr-Lys-Pro-Asp-Val Thr-Lys-Pro-Asp-Val 895 Thr-Lys-Pro-Asp-Arg-Val Thr-Lys-Pro-Asp-Arg-Val Thr-Lys-Pro-Asp-Arg-Val 896 Thr-Lys-Pro-Asp-Phe-Val Thr-Lys-Pro-Asp-Phe-Val Thr-Lys-Pro-Asp-Phe-Val 897 Thr-Lys-Pro-Asp-Tyr-Val Thr-Lys-Pro-Asp-Tyr-Val Thr-Lys-Pro-Asp-Tyr-Val 898 Thr-Lys-Pro-Asp-His-Val Thr-Lys-Pro-Asp-His-Val Thr-Lys-Pro-Asp-His-Val 899 Thr-Lys-Pro-Asp-Pro-Val Thr-Lys-Pro-Asp-Pro-Val Thr-Lys-Pro-Asp-Pro-Val 900 Thr-Lys-Pro-Asp-Lys-Val Thr-Lys-Pro-Asp-Lys-Val Thr-Lys-Pro-Asp-Lys-Val 901 Thr-Lys-Pro-Trp-Val Thr-Lys-Pro-Trp-Val Thr-Lys-Pro-Trp-Val 902 Thr-Lys-Pro-Trp-Arg-Val Thr-Lys-Pro-Trp-Arg-Val Thr-Lys-Pro-Trp-Arg-Val 903 Thr-Lys-Pro-Trp-Phe-Val Thr-Lys-Pro-Trp-Phe-Val Thr-Lys-Pro-Trp-Phe-Val 904 Thr-Lys-Pro-Trp-Tyr-Val Thr-Lys-Pro-Trp-Tyr-Val Thr-Lys-Pro-Trp-Tyr-Val 905 Thr-Lys-Pro-Trp-His-Val Thr-Lys-Pro-Trp-His-Val Thr-Lys-Pro-Trp-His-Val 906 Thr-Lys-Pro-Trp-Pro-Val Thr-Lys-Pro-Trp-Pro-Val Thr-Lys-Pro-Trp-Pro-Val 907 Thr-Lys-Pro-Trp-Lys-Val Thr-Lys-Pro-Trp-Lys-Val Thr-Lys-Pro-Trp-Lys-Val 908 Thr-Lys-Pro-Gln-Val Thr-Lys-Pro-Gln-Val Thr-Lys-Pro-Gln-Val 909 Thr-Lys-Pro-Gln-Arg-Val Thr-Lys-Pro-Gln-Arg-Val Thr-Lys-Pro-Gln-Arg-Val 910 Thr-Lys-Pro-Gln-Phe-Val Thr-Lys-Pro-Gln-Phe-Val Thr-Lys-Pro-Gln-Phe-Val 911 Thr-Lys-Pro-Gln-Tyr-Val Thr-Lys-Pro-Gln-Tyr-Val Thr-Lys-Pro-Gln-Tyr-Val 912 Thr-Lys-Pro-Gln-His-Val Thr-Lys-Pro-Gln-His-Val Thr-Lys-Pro-Gln-His-Val 913 Thr-Lys-Pro-Gln-Pro-Val Thr-Lys-Pro-Gln-Pro-Val Thr-Lys-Pro-Gln-Pro-Val 914 Thr-Lys-Pro-Gln-Lys-Val Thr-Lys-Pro-Gln-Lys-Val Thr-Lys-Pro-Gln-Lys-Val 915 Thr-Lys-Pro-Asn-Val Thr-Lys-Pro-Asn-Val Thr-Lys-Pro-Asn-Val 916 Thr-Lys-Pro-Asn-Arg-Val Thr-Lys-Pro-Asn-Arg-Val Thr-Lys-Pro-Asn-Arg-Val 917 Thr-Lys-Pro-Asn-Phe-Val Thr-Lys-Pro-Asn-Phe-Val Thr-Lys-Pro-Asn-Phe-Val 918 Thr-Lys-Pro-Asn-Tyr-Val Thr-Lys-Pro-Asn-Tyr-Val Thr-Lys-Pro-Asn-Tyr-Val 919 Thr-Lys-Pro-Asn-His-Val Thr-Lys-Pro-Asn-His-Val Thr-Lys-Pro-Asn-His-Val 920 Thr-Lys-Pro-Asn-Pro-Val Thr-Lys-Pro-Asn-Pro-Val Thr-Lys-Pro-Asn-Pro-Val 921 Thr-Lys-Pro-Asn-Lys-Val Thr-Lys-Pro-Asn-Lys-Val Thr-Lys-Pro-Asn-Lys-Val 922 Thr-Lys-Pro-Tyr-Val Thr-Lys-Pro-Tyr-Val Thr-Lys-Pro-Tyr-Val 923 Thr-Lys-Pro-Tyr-Arg-Val Thr-Lys-Pro-Tyr-Arg-Val Thr-Lys-Pro-Tyr-Arg-Val 924 Thr-Lys-Pro-Tyr-Phe-Val Thr-Lys-Pro-Tyr-Phe-Val Thr-Lys-Pro-Tyr-Phe-Val 925 Thr-Lys-Pro-Tyr-Tyr-Val Thr-Lys-Pro-Tyr-Tyr-Val Thr-Lys-Pro-Tyr-Tyr-Val 926 Thr-Lys-Pro-Tyr-His-Val Thr-Lys-Pro-Tyr-His-Val Thr-Lys-Pro-Tyr-His-Val 927 Thr-Lys-Pro-Tyr-Pro-Val Thr-Lys-Pro-Tyr-Pro-Val Thr-Lys-Pro-Tyr-Pro-Val 928 Thr-Lys-Pro-Tyr-Lys-Val Thr-Lys-Pro-Tyr-Lys-Val Thr-Lys-Pro-Tyr-Lys-Val 929 Thr-Lys-Pro-Arg-Val Thr-Lys-Pro-Arg-Val Thr-Lys-Pro-Arg-Val 930 Thr-Lys-Pro-Arg-Arg-Val Thr-Lys-Pro-Arg-Arg-Val Thr-Lys-Pro-Arg-Arg-Val 931 Thr-Lys-Pro-Arg-Phe-Val Thr-Lys-Pro-Arg-Phe-Val Thr-Lys-Pro-Arg-Phe-Val 932 Thr-Lys-Pro-Arg-Tyr-Val Thr-Lys-Pro-Arg-Tyr-Val Thr-Lys-Pro-Arg-Tyr-Val 933 Thr-Lys-Pro-Arg-His-Val Thr-Lys-Pro-Arg-His-Val Thr-Lys-Pro-Arg-His-Val 934 Thr-Lys-Pro-Arg-Pro-Val Thr-Lys-Pro-Arg-Pro-Val Thr-Lys-Pro-Arg-Pro-Val 935 Thr-Lys-Pro-Arg-Lys-Val Thr-Lys-Pro-Arg-Lys-Val Thr-Lys-Pro-Arg-Lys-Val 936 Met-Thr-Lys-Pro-Val Met-Thr-Lys-Pro-Val Met-Thr-Lys-Pro-Val 937 Met-Thr-Lys-Pro-Arg-Val Met-Thr-Lys-Pro-Arg-Val Met-Thr-Lys-Pro-Arg-Val 938 Met-Thr-Lys-Pro-Phe-Val Met-Thr-Lys-Pro-Phe-Val Met-Thr-Lys-Pro-Phe-Val 939 Met-Thr-Lys-Pro-Tyr-Val Met-Thr-Lys-Pro-Tyr-Val Met-Thr-Lys-Pro-Tyr-Val 940 Met-Thr-Lys-Pro-His-Val Met-Thr-Lys-Pro-His-Val Met-Thr-Lys-Pro-His-Val 941 Met-Thr-Lys-Pro-Lys-Val Met-Thr-Lys-Pro-Lys-Val Met-Thr-Lys-Pro-Lys-Val 942 Met-Thr-Lys-Pro-Gly-Val Met-Thr-Lys-Pro-Gly-Val Met-Thr-Lys-Pro-Gly-Val 943 Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Arg- Met-Thr-Lys-Pro-Gly- 944 Arg-Val Val Arg-Val Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Phe- Met-Thr-Lys-Pro-Gly- 945 Phe-Val Val Phe-Val Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Tyr- Met-Thr-Lys-Pro-Gly- 946 Tyr-Val Val Tyr-Val Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-His- Met-Thr-Lys-Pro-Gly-His- 947 His-Val Val Val Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Pro- Met-Thr-Lys-Pro-Gly-Pro- 948 Pro-Val Val Val Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Lys- Met-Thr-Lys-Pro-Gly- 949 Lys-Val Val Lys-Val Met-Thr-Lys-Pro-Asp-Val Met-Thr-Lys-Pro-Asp-Val Met-Thr-Lys-Pro-Asp-Val 950 Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Arg- Met-Thr-Lys-Pro-Asp- 951 Arg-Val Val Arg-Val Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Phe- Met-Thr-Lys-Pro-Asp- 952 Phe-Val Val Phe-Val Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Tyr- Met-Thr-Lys-Pro-Asp- 953 Tyr-Val Val Tyr-Val Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-His- Met-Thr-Lys-Pro-Asp- 954 His-Val Val His-Val Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Pro- Met-Thr-Lys-Pro-Asp- 955 Pro-Val Val Pro-Val Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Lys- Met-Thr-Lys-Pro-Asp- 956 Lys-Val Val Lys-Val Met-Thr-Lys-Pro-Trp-Val Met-Thr-Lys-Pro-Trp-Val Met-Thr-Lys-Pro-Trp-Val 957 Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Arg- Met-Thr-Lys-Pro-Trp- 958 Arg-Val Val Arg-Val Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Phe- Met-Thr-Lys-Pro-Trp- 959 Phe-Val Val Phe-Val Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Tyr- Met-Thr-Lys-Pro-Trp-Tyr- 960 Tyr-Val Val Val Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-His- Met-Thr-Lys-Pro-Trp-His- 961 His-Val Val Val Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Pro- Met-Thr-Lys-Pro-Trp-Pro- 962 Pro-Val Val Val Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Lys- Met-Thr-Lys-Pro-Trp- 963 Lys-Val Val Lys-Val Met-Thr-Lys-Pro-Gln-Val Met-Thr-Lys-Pro-Gln-Val Met-Thr-Lys-Pro-Gln-Val 964 Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Arg- Met-Thr-Lys-Pro-Gln- 965 Arg-Val Val Arg-Val Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Phe- Met-Thr-Lys-Pro-Gln- 966 Phe-Val Val Phe-Val Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Tyr- Met-Thr-Lys-Pro-Gln- 967 Tyr-Val Val Tyr-Val Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-His- Met-Thr-Lys-Pro-Gln-His- 968 His-Val Val Val Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Pro- Met-Thr-Lys-Pro-Gln-Pro- 969 Pro-Val Val Val Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Lys- Met-Thr-Lys-Pro-Gln- 970 Lys-Val Val Lys-Val Met-Thr-Lys-Pro-Asn-Val Met-Thr-Lys-Pro-Asn-Val Met-Thr-Lys-Pro-Asn-Val 971 Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Arg- Met-Thr-Lys-Pro-Asn- 972

Arg-Val Val Arg-Val Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Phe- Met-Thr-Lys-Pro-Asn- 973 Phe-Val Val Phe-Val Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Tyr- Met-Thr-Lys-Pro-Asn- 974 Tyr-Val Val Tyr-Val Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-His- Met-Thr-Lys-Pro-Asn- 975 His-Val Val His-Val Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Pro- Met-Thr-Lys-Pro-Asn- 976 Pro-Val Val Pro-Val Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Lys- Met-Thr-Lys-Pro-Asn- 977 Lys-Val Val Lys-Val Met-Thr-Lys-Pro-Tyr-Val Met-Thr-Lys-Pro-Tyr-Val Met-Thr-Lys-Pro-Tyr-Val 978 Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Arg- Met-Thr-Lys-Pro-Tyr- 979 Arg-Val Val Arg-Val Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Phe- Met-Thr-Lys-Pro-Tyr- 980 Phe-Val Val Phe-Val Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- 981 Tyr-Val Val Val Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-His- Met-Thr-Lys-Pro-Tyr-His- 982 His-Val Val Val Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Pro- Met-Thr-Lys-Pro-Tyr-Pro- 983 Pro-Val Val Val Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Lys- Met-Thr-Lys-Pro-Tyr- 984 Lys-Val Val Lys-Val Met-Thr-Lys-Pro-Arg-Val Met-Thr-Lys-Pro-Arg-Val Met-Thr-Lys-Pro-Arg-Val 985 Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Arg- Met-Thr-Lys-Pro-Arg- 986 Arg-Val Val Arg-Val Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Phe- Met-Thr-Lys-Pro-Arg- 987 Phe-Val Val Phe-Val Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Tyr- Met-Thr-Lys-Pro-Arg- 988 Tyr-Val Val Tyr-Val Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-His- Met-Thr-Lys-Pro-Arg- 989 His-Val Val His-Val Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Pro- Met-Thr-Lys-Pro-Arg- 990 Pro-Val Val Pro-Val Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Lys- Met-Thr-Lys-Pro-Arg- 991 Lys-Val Val Lys-Val Met(O)-Thr-Lys-Pro-Val Met(O)-Thr-Lys-Pro-Val Met(O)-Thr-Lys-Pro-Val 992 Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 993 Val Val Val Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- 994 Val Val Val Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 995 Val Val Val Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 996 Val Val Val Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- 997 Val Val Val Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- 998 Val Val Val Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 999 Val Val Val Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1000 Arg-Val Arg-Val Arg-Val Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1001 Phe-Val Phe-Val Phe-Val Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1002 Tyr-Val Tyr-Val Tyr-Val Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1003 His-Val His-Val His-Val Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1004 Pro-Val Pro-Val Pro-Val Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1005 Lys-Val Lys-Val Lys-Val Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1006 Val Val Val Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1007 Arg-Val Arg-Val Arg-Val Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1008 Phe-Val Phe-Val Phe-Val Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1009 Tyr-Val Tyr-Val Tyr-Val Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1010 His-Val His-Val His-Val Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1011 Pro-Val Pro-Val Pro-Val Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1012 Lys-Val Lys-Val Lys-Val Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1013 Val Val Val Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1014 Arg-Val Arg-Val Arg-Val Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1015 Phe-Val Phe-Val Phe-Val Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1016 Tyr-Val Tyr-Val Tyr-Val Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1017 His-Val His-Val His-Val Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1018 Pro-Val Pro-Val Pro-Val Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1019 Lys-Val Lys-Val Lys-Val Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1020 Val Val Val Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1021 Arg-Val Arg-Val Arg-Val Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1022 Phe-Val Phe-Val Phe-Val Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1023 Tyr-Val Tyr-Val Tyr-Val Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1024 His-Val His-Val His-Val Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1025 Pro-Val Pro-Val Pro-Val Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1026 Lys-Val Lys-Val Lys-Val Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1027 Val Val Val Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1028 Arg-Val Arg-Val Arg-Val Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1029 Phe-Val Phe-Val Phe-Val Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1030 Tyr-Val Tyr-Val Tyr-Val Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1031 His-Val His-Val His-Val Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1032 Pro-Val Pro-Val Pro-Val Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1033 Lys-Val Lys-Val Lys-Val Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1034 Val Val Val Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1035 Arg-Val Arg-Val Arg-Val Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1036 Phe-Val Phe-Val Phe-Val Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1037 Tyr-Val Tyr-Val Tyr-Val Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1038 His-Val His-Val His-Val Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1039 Pro-Val Pro-Val Pro-Val

Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1040 Lys-Val Lys-Val Lys-Val Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1041 Val Val Val Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1042 Arg-Val Arg-Val Arg-Val Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1043 Phe-Val Phe-Val Phe-Val Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1044 Tyr-Val Tyr-Val Tyr-Val Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1045 His-Val His-Val His-Val Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1046 Pro-Val Pro-Val Pro-Val Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1047 Lys-Val Lys-Val Lys-Val Thr-Thr-Lys-Pro-Val Thr-Thr-Lys-Pro-Val Thr-Thr-Lys-Pro-Val 1048 Thr-Thr-Lys-Pro-Arg-Val Thr-Thr-Lys-Pro-Arg-Val Thr-Thr-Lys-Pro-Arg-Val 1049 Thr-Thr-Lys-Pro-Phe-Val Thr-Thr-Lys-Pro-Phe-Val Thr-Thr-Lys-Pro-Phe-Val 1050 Thr-Thr-Lys-Pro-Tyr-Val Thr-Thr-Lys-Pro-Tyr-Val Thr-Thr-Lys-Pro-Tyr-Val 1051 Thr-Thr-Lys-Pro-Gly-Val Thr-Thr-Lys-Pro-Gly-Val Thr-Thr-Lys-Pro-Gly-Val 1052 Thr-Thr-Lys-Pro-His-Val Thr-Thr-Lys-Pro-His-Val Thr-Thr-Lys-Pro-His-Val 1053 Thr-Thr-Lys-Pro-Lys-Val Thr-Thr-Lys-Pro-Lys-Val Thr-Thr-Lys-Pro-Lys-Val 1054 Thr-Thr-Lys-Pro-Gly-Val Thr-Thr-Lys-Pro-Gly-Val Thr-Thr-Lys-Pro-Gly-Val 1055 Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Arg- Thr-Thr-Lys-Pro-Gly-Arg- 1056 Arg-Val Val Val Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Phe- Thr-Thr-Lys-Pro-Gly-Phe- 1057 Phe-Val Val Val Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Tyr- Thr-Thr-Lys-Pro-Gly-Tyr- 1058 Tyr-Val Val Val Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- 1059 Val Val Val Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- 1060 Val Val Val Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Lys- Thr-Thr-Lys-Pro-Gly-Lys- 1061 Lys-Val Val Val Thr-Thr-Lys-Pro-Asp-Val Thr-Thr-Lys-Pro-Asp-Val Thr-Thr-Lys-Pro-Asp-Val 1062 Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Arg- Thr-Thr-Lys-Pro-Asp- 1063 Arg-Val Val Arg-Val Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Phe- Thr-Thr-Lys-Pro-Asp- 1064 Phe-Val Val Phe-Val Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Tyr- Thr-Thr-Lys-Pro-Asp-Tyr- 1065 Tyr-Val Val Val Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-His- Thr-Thr-Lys-Pro-Asp-His- 1066 His-Val Val Val Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Pro- Thr-Thr-Lys-Pro-Asp-Pro- 1067 Pro-Val Val Val Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Lys- Thr-Thr-Lys-Pro-Asp- 1068 Lys-Val Val Lys-Val Thr-Thr-Lys-Pro-Trp-Val Thr-Thr-Lys-Pro-Trp-Val Thr-Thr-Lys-Pro-Trp-Val 1069 Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Arg- Thr-Thr-Lys-Pro-Trp-Arg- 1070 Arg-Val Val Val Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Phe- Thr-Thr-Lys-Pro-Trp-Phe- 1071 Phe-Val Val Val Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- 1072 Val Val Val Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- 1073 Val Val Val Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- 1074 Val Val Val Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Lys- Thr-Thr-Lys-Pro-Trp-Lys- 1075 Lys-Val Val Val Thr-Thr-Lys-Pro-Gln-Val Thr-Thr-Lys-Pro-Gln-Val Thr-Thr-Lys-Pro-Gln-Val 1076 Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Arg- Thr-Thr-Lys-Pro-Gln-Arg- 1077 Arg-Val Val Val Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Phe- Thr-Thr-Lys-Pro-Gln-Phe- 1078 Phe-Val Val Val Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Tyr- Thr-Thr-Lys-Pro-Gln-Tyr- 1079 Tyr-Val Val Val Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- 1080 Val Val Val Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- 1081 Val Val Val Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Lys- Thr-Thr-Lys-Pro-Gln-Lys- 1082 Lys-Val Val Val Thr-Thr-Lys-Pro-Asn-Val Thr-Thr-Lys-Pro-Asn-Val Thr-Thr-Lys-Pro-Asn-Val 1083 Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Arg- Thr-Thr-Lys-Pro-Asn- 1084 Arg-Val Val Arg-Val Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Phe- Thr-Thr-Lys-Pro-Asn- 1085 Phe-Val Val Phe-Val Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Tyr- Thr-Thr-Lys-Pro-Asn-Tyr- 1086 Tyr-Val Val Val Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-His- Thr-Thr-Lys-Pro-Asn-His- 1087 His-Val Val Val Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Pro- Thr-Thr-Lys-Pro-Asn-Pro- 1088 Pro-Val Val Val Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Lys- Thr-Thr-Lys-Pro-Asn- 1089 Lys-Val Val Lys-Val Thr-Thr-Lys-Pro-Tyr-Val Thr-Thr-Lys-Pro-Tyr-Val Thr-Thr-Lys-Pro-Tyr-Val 1090 Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Arg- Thr-Thr-Lys-Pro-Tyr-Arg- 1091 Arg-Val Val Val Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Phe- Thr-Thr-Lys-Pro-Tyr-Phe- 1092 Phe-Val Val Val Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- 1093 Val Val Val Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- 1094 Val Val Val Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- 1095 Val Val Val Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Lys- Thr-Thr-Lys-Pro-Tyr-Lys- 1096 Lys-Val Val Val Thr-Thr-Lys-Pro-Arg-Val Thr-Thr-Lys-Pro-Arg-Val Thr-Thr-Lys-Pro-Arg-Val 1097 Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Arg- Thr-Thr-Lys-Pro-Arg- 1098 Arg-Val Val Arg-Val Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Phe- Thr-Thr-Lys-Pro-Arg-Phe- 1099 Phe-Val Val Val Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Tyr- Thr-Thr-Lys-Pro-Arg-Tyr- 1100 Tyr-Val Val Val Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-His- Thr-Thr-Lys-Pro-Arg-His- 1101 His-Val Val Val Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Pro- Thr-Thr-Lys-Pro-Arg-Pro- 1102 Pro-Val Val Val Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Lys- Thr-Thr-Lys-Pro-Arg-Lys- 1103 Lys-Val Val Val Ala-Thr-Lys-Pro-Val Ala-Thr-Lys-Pro-Val Ala-Thr-Lys-Pro-Val 1104 Ala-Thr-Lys-Pro-Arg-Val Ala-Thr-Lys-Pro-Arg-Val Ala-Thr-Lys-Pro-Arg-Val 1105 Ala-Thr-Lys-Pro-Phe-Val Ala-Thr-Lys-Pro-Phe-Val Ala-Thr-Lys-Pro-Phe-Val 1106 Ala-Thr-Lys-Pro-Tyr-Val Ala-Thr-Lys-Pro-Tyr-Val Ala-Thr-Lys-Pro-Tyr-Val 1107 Ala-Thr-Lys-Pro-Gly-Val Ala-Thr-Lys-Pro-Gly-Val Ala-Thr-Lys-Pro-Gly-Val 1108 Ala-Thr-Lys-Pro-His-Val Ala-Thr-Lys-Pro-His-Val Ala-Thr-Lys-Pro-His-Val 1109

Ala-Thr-Lys-Pro-Lys-Val Ala-Thr-Lys-Pro-Lys-Val Ala-Thr-Lys-Pro-Lys-Val 1110 Ala-Thr-Lys-Pro-Gly-Val Ala-Thr-Lys-Pro-Gly-Val Ala-Thr-Lys-Pro-Gly-Val 1111 Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Arg- Ala-Thr-Lys-Pro-Gly-Arg- 1112 Arg-Val Val Val Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Phe- Ala-Thr-Lys-Pro-Gly-Phe- 1113 Phe-Val Val Val Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Tyr- Ala-Thr-Lys-Pro-Gly-Tyr- 1114 Tyr-Val Val Val Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- 1115 Val Val Val Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- 1116 Val Val Val Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Lys- Ala-Thr-Lys-Pro-Gly-Lys- 1117 Lys-Val Val Val Ala-Thr-Lys-Pro-Asp-Val Ala-Thr-Lys-Pro-Asp-Val Ala-Thr-Lys-Pro-Asp-Val 1118 Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Arg- Ala-Thr-Lys-Pro-Asp- 1119 Arg-Val Val Arg-Val Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Phe- Ala-Thr-Lys-Pro-Asp- 1120 Phe-Val Val Phe-Val Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Tyr- Ala-Thr-Lys-Pro-Asp-Tyr- 1121 Tyr-Val Val Val Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-His- Ala-Thr-Lys-Pro-Asp-His- 1122 His-Val Val Val Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Pro- Ala-Thr-Lys-Pro-Asp-Pro- 1123 Pro-Val Val Val Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Lys- Ala-Thr-Lys-Pro-Asp- 1124 Lys-Val Val Lys-Val Ala-Thr-Lys-Pro-Trp-Val Ala-Thr-Lys-Pro-Trp-Val Ala-Thr-Lys-Pro-Trp-Val 1125 Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Arg- Ala-Thr-Lys-Pro-Trp-Arg- 1126 Arg-Val Val Val Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Phe- Ala-Thr-Lys-Pro-Trp-Phe- 1127 Phe-Val Val Val Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- 1128 Val Val Val Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- 1129 Val Val Val Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- 1130 Val Val Val Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Lys- Ala-Thr-Lys-Pro-Trp-Lys- 1131 Lys-Val Val Val Ala-Thr-Lys-Pro-Gln-Val Ala-Thr-Lys-Pro-Gln-Val Ala-Thr-Lys-Pro-Gln-Val 1132 Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Arg- Ala-Thr-Lys-Pro-Gln-Arg- 1133 Arg-Val Val Val Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Phe- Ala-Thr-Lys-Pro-Gln-Phe- 1134 Phe-Val Val Val Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Tyr- Ala-Thr-Lys-Pro-Gln-Tyr- 1135 Tyr-Val Val Val Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- 1136 Val Val Val Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- 1137 Val Val Val Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Lys- Ala-Thr-Lys-Pro-Gln-Lys- 1138 Lys-Val Val Val Ala-Thr-Lys-Pro-Asn-Val Ala-Thr-Lys-Pro-Asn-Val Ala-Thr-Lys-Pro-Asn-Val 1139 Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Arg- Ala-Thr-Lys-Pro-Asn- 1140 Arg-Val Val Arg-Val Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Phe- Ala-Thr-Lys-Pro-Asn- 1141 Phe-Val Val Phe-Val Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Tyr- Ala-Thr-Lys-Pro-Asn-Tyr- 1142 Tyr-Val Val Val Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-His- Ala-Thr-Lys-Pro-Asn-His- 1143 His-Val Val Val Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Pro- Ala-Thr-Lys-Pro-Asn-Pro- 1144 Pro-Val Val Val Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Lys- Ala-Thr-Lys-Pro-Asn- 1145 Lys-Val Val Lys-Val Ala-Thr-Lys-Pro-Tyr-Val Ala-Thr-Lys-Pro-Tyr-Val Ala-Thr-Lys-Pro-Tyr-Val 1146 Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Arg- Ala-Thr-Lys-Pro-Tyr-Arg- 1147 Arg-Val Val Val Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Phe- Ala-Thr-Lys-Pro-Tyr-Phe- 1148 Phe-Val Val Val Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- 1149 Val Val Val Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- 1150 Val Val Val Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- 1151 Val Val Val Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Lys- Ala-Thr-Lys-Pro-Tyr-Lys- 1152 Lys-Val Val Val Ala-Thr-Lys-Pro-Arg-Val Ala-Thr-Lys-Pro-Arg-Val Ala-Thr-Lys-Pro-Arg-Val 1153 Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Arg- Ala-Thr-Lys-Pro-Arg- 1154 Arg-Val Val Arg-Val Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Phe- Ala-Thr-Lys-Pro-Arg-Phe- 1155 Phe-Val Val Val Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Tyr- Ala-Thr-Lys-Pro-Arg-Tyr- 1156 Tyr-Val Val Val Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-His- Ala-Thr-Lys-Pro-Arg-His- 1157 His-Val Val Val Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Pro- Ala-Thr-Lys-Pro-Arg-Pro- 1158 Pro-Val Val Val Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Lys- Ala-Thr-Lys-Pro-Arg-Lys- 1159 Lys-Val Val Val His-Thr-Lys-Pro-Val His-Thr-Lys-Pro-Val His-Thr-Lys-Pro-Val 1160 His-Thr-Lys-Pro-Arg-Val His-Thr-Lys-Pro-Arg-Val His-Thr-Lys-Pro-Arg-Val 1161 His-Thr-Lys-Pro-Phe-Val His-Thr-Lys-Pro-Phe-Val His-Thr-Lys-Pro-Phe-Val 1162 His-Thr-Lys-Pro-Tyr-Val His-Thr-Lys-Pro-Tyr-Val His-Thr-Lys-Pro-Tyr-Val 1163 His-Thr-Lys-Pro-Gly-Val His-Thr-Lys-Pro-Gly-Val His-Thr-Lys-Pro-Gly-Val 1164 His-Thr-Lys-Pro-His-Val His-Thr-Lys-Pro-His-Val His-Thr-Lys-Pro-His-Val 1165 His-Thr-Lys-Pro-Lys-Val His-Thr-Lys-Pro-Lys-Val His-Thr-Lys-Pro-Lys-Val 1166 His-Thr-Lys-Pro-Gly-Val His-Thr-Lys-Pro-Gly-Val His-Thr-Lys-Pro-Gly-Val 1167 His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Arg- His-Thr-Lys-Pro-Gly-Arg- 1168 Arg-Val Val Val His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Phe- His-Thr-Lys-Pro-Gly-Phe- 1169 Phe-Val Val Val His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- 1170 Val Val Val His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- 1171 Val Val Val His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- 1172 Val Val Val His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Lys- His-Thr-Lys-Pro-Gly-Lys- 1173 Lys-Val Val Val His-Thr-Lys-Pro-Asp-Val His-Thr-Lys-Pro-Asp-Val His-Thr-Lys-Pro-Asp-Val 1174 His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Arg- His-Thr-Lys-Pro-Asp- 1175 Arg-Val Val Arg-Val His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Phe- His-Thr-Lys-Pro-Asp-Phe- 1176 Phe-Val Val Val His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Tyr- His-Thr-Lys-Pro-Asp-Tyr- 1177 Tyr-Val Val Val His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-His- His-Thr-Lys-Pro-Asp-His- 1178 His-Val Val Val

His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Pro- His-Thr-Lys-Pro-Asp-Pro- 1179 Pro-Val Val Val His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Lys- His-Thr-Lys-Pro-Asp-Lys- 1180 Lys-Val Val Val His-Thr-Lys-Pro-Trp-Val His-Thr-Lys-Pro-Trp-Val His-Thr-Lys-Pro-Trp-Val 1181 His-Thr-Lys-Pro-Trp- His-Thr-Lys-Pro-Trp-Arg- His-Thr-Lys-Pro-Trp-Arg- 1182 Arg-Val Val Val His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- 1183 Val Val Val His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- 1184 Val Val Val His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- 1185 Val Val Val His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- 1186 Val Val Val His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- 1187 Val Val Val His-Thr-Lys-Pro-Gln-Val His-Thr-Lys-Pro-Gln-Val His-Thr-Lys-Pro-Gln-Val 1188 His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Arg- His-Thr-Lys-Pro-Gln-Arg- 1189 Arg-Val Val Val His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Phe- His-Thr-Lys-Pro-Gln-Phe- 1190 Phe-Val Val Val His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- 1191 Val Val Val His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- 1192 Val Val Val His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- 1193 Val Val Val His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Lys- His-Thr-Lys-Pro-Gln-Lys- 1194 Lys-Val Val Val His-Thr-Lys-Pro-Asn-Val His-Thr-Lys-Pro-Asn-Val His-Thr-Lys-Pro-Asn-Val 1195 His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Arg- His-Thr-Lys-Pro-Asn- 1196 Arg-Val Val Arg-Val His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Phe- His-Thr-Lys-Pro-Asn-Phe- 1197 Phe-Val Val Val His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Tyr- His-Thr-Lys-Pro-Asn-Tyr- 1198 Tyr-Val Val Val His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-His- His-Thr-Lys-Pro-Asn-His- 1199 His-Val Val Val His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Pro- His-Thr-Lys-Pro-Asn-Pro- 1200 Pro-Val Val Val His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Lys- His-Thr-Lys-Pro-Asn-Lys- 1201 Lys-Val Val Val His-Thr-Lys-Pro-Tyr-Val His-Thr-Lys-Pro-Tyr-Val His-Thr-Lys-Pro-Tyr-Val 1202 His-Thr-Lys-Pro-Tyr- His-Thr-Lys-Pro-Tyr-Arg- His-Thr-Lys-Pro-Tyr-Arg- 1203 Arg-Val Val Val His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- 1204 Val Val Val His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- 1205 Val Val Val His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- 1206 Val Val Val His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- 1207 Val Val Val His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- 1208 Val Val Val His-Thr-Lys-Pro-Arg-Val His-Thr-Lys-Pro-Arg-Val His-Thr-Lys-Pro-Arg-Val 1209 His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Arg- His-Thr-Lys-Pro-Arg-Arg- 1210 Arg-Val Val Val His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Phe- His-Thr-Lys-Pro-Arg-Phe- 1211 Phe-Val Val Val His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Tyr- His-Thr-Lys-Pro-Arg-Tyr- 1212 Tyr-Val Val Val His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- 1213 Val Val Val His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- 1214 Val Val Val His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Lys- His-Thr-Lys-Pro-Arg-Lys- 1215 Lys-Val Val Val Lys-Thr-Lys-Pro-Val Lys-Thr-Lys-Pro-Val Lys-Thr-Lys-Pro-Val 1216 Lys-Thr-Lys-Pro-Arg-Val Lys-Thr-Lys-Pro-Arg-Val Lys-Thr-Lys-Pro-Arg-Val 1217 Lys-Thr-Lys-Pro-Phe-Val Lys-Thr-Lys-Pro-Phe-Val Lys-Thr-Lys-Pro-Phe-Val 1218 Lys-Thr-Lys-Pro-Tyr-Val Lys-Thr-Lys-Pro-Tyr-Val Lys-Thr-Lys-Pro-Tyr-Val 1219 Lys-Thr-Lys-Pro-Gly-Val Lys-Thr-Lys-Pro-Gly-Val Lys-Thr-Lys-Pro-Gly-Val 1220 Lys-Thr-Lys-Pro-His-Val Lys-Thr-Lys-Pro-His-Val Lys-Thr-Lys-Pro-His-Val 1221 Lys-Thr-Lys-Pro-Lys-Val Lys-Thr-Lys-Pro-Lys-Val Lys-Thr-Lys-Pro-Lys-Val 1222 Lys-Thr-Lys-Pro-Gly-Val Lys-Thr-Lys-Pro-Gly-Val Lys-Thr-Lys-Pro-Gly-Val 1223 Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Arg- Lys-Thr-Lys-Pro-Gly- 1224 Arg-Val Val Arg-Val Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Phe- Lys-Thr-Lys-Pro-Gly-Phe- 1225 Phe-Val Val Val Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Tyr- Lys-Thr-Lys-Pro-Gly-Tyr- 1226 Tyr-Val Val Val Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-His- Lys-Thr-Lys-Pro-Gly-His- 1227 His-Val Val Val Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Pro- Lys-Thr-Lys-Pro-Gly-Pro- 1228 Pro-Val Val Val Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Lys- Lys-Thr-Lys-Pro-Gly-Lys- 1229 Lys-Val Val Val Lys-Thr-Lys-Pro-Asp-Val Lys-Thr-Lys-Pro-Asp-Val Lys-Thr-Lys-Pro-Asp-Val 1230 Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Arg- Lys-Thr-Lys-Pro-Asp- 1231 Arg-Val Val Arg-Val Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Phe- Lys-Thr-Lys-Pro-Asp- 1232 Phe-Val Val Phe-Val Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Tyr- Lys-Thr-Lys-Pro-Asp- 1233 Tyr-Val Val Tyr-Val Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-His- Lys-Thr-Lys-Pro-Asp-His- 1234 His-Val Val Val Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Pro- Lys-Thr-Lys-Pro-Asp-Pro- 1235 Pro-Val Val Val Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Lys- Lys-Thr-Lys-Pro-Asp- 1236 Lys-Val Val Lys-Val Lys-Thr-Lys-Pro-Trp-Val Lys-Thr-Lys-Pro-Trp-Val Lys-Thr-Lys-Pro-Trp-Val 1237 Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Arg- Lys-Thr-Lys-Pro-Trp-Arg- 1238 Arg-Val Val Val Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Phe- Lys-Thr-Lys-Pro-Trp-Phe- 1239 Phe-Val Val Val Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Tyr- Lys-Thr-Lys-Pro-Trp-Tyr- 1240 Tyr-Val Val Val Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- 1241 Val Val Val Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- 1242 Val Val Val Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Lys- Lys-Thr-Lys-Pro-Trp-Lys- 1243 Lys-Val Val Val Lys-Thr-Lys-Pro-Gln-Val Lys-Thr-Lys-Pro-Gln-Val Lys-Thr-Lys-Pro-Gln-Val 1244 Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Arg- Lys-Thr-Lys-Pro-Gln- 1245 Arg-Val Val Arg-Val Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Phe- Lys-Thr-Lys-Pro-Gln-Phe- 1246 Phe-Val Val Val Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Tyr- Lys-Thr-Lys-Pro-Gln-Tyr- 1247 Tyr-Val Val Val

Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-His- Lys-Thr-Lys-Pro-Gln-His- 1248 His-Val Val Val Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Pro- Lys-Thr-Lys-Pro-Gln-Pro- 1249 Pro-Val Val Val Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Lys- Lys-Thr-Lys-Pro-Gln-Lys- 1250 Lys-Val Val Val Lys-Thr-Lys-Pro-Asn-Val Lys-Thr-Lys-Pro-Asn-Val Lys-Thr-Lys-Pro-Asn-Val 1251 Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Arg- Lys-Thr-Lys-Pro-Asn- 1252 Arg-Val Val Arg-Val Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Phe- Lys-Thr-Lys-Pro-Asn- 1253 Phe-Val Val Phe-Val Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Tyr- Lys-Thr-Lys-Pro-Asn- 1254 Tyr-Val Val Tyr-Val Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-His- Lys-Thr-Lys-Pro-Asn-His- 1255 His-Val Val Val Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Pro- Lys-Thr-Lys-Pro-Asn-Pro- 1256 Pro-Val Val Val Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Lys- Lys-Thr-Lys-Pro-Asn- 1257 Lys-Val Val Lys-Val Lys-Thr-Lys-Pro-Tyr-Val Lys-Thr-Lys-Pro-Tyr-Val Lys-Thr-Lys-Pro-Tyr-Val 1258 Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Arg- Lys-Thr-Lys-Pro-Tyr-Arg- 1259 Arg-Val Val Val Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Phe- Lys-Thr-Lys-Pro-Tyr-Phe- 1260 Phe-Val Val Val Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- 1261 Tyr-Val Val Val Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- 1262 Val Val Val Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- 1263 Val Val Val Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Lys- Lys-Thr-Lys-Pro-Tyr-Lys- 1264 Lys-Val Val Val Lys-Thr-Lys-Pro-Arg-Val Lys-Thr-Lys-Pro-Arg-Val Lys-Thr-Lys-Pro-Arg-Val 1265 Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Arg- Lys-Thr-Lys-Pro-Arg- 1266 Arg-Val Val Arg-Val Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Phe- Lys-Thr-Lys-Pro-Arg- 1267 Phe-Val Val Phe-Val Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Tyr- Lys-Thr-Lys-Pro-Arg-Tyr- 1268 Tyr-Val Val Val Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-His- Lys-Thr-Lys-Pro-Arg-His- 1269 His-Val Val Val Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Pro- Lys-Thr-Lys-Pro-Arg-Pro- 1270 Pro-Val Val Val Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Lys- Lys-Thr-Lys-Pro-Arg- 1271 Lys-Val Val Lys-Val Gly-Thr-Lys-Pro-Val Gly-Thr-Lys-Pro-Val Gly-Thr-Lys-Pro-Val 1272 Gly-Thr-Lys-Pro-Arg-Val Gly-Thr-Lys-Pro-Arg-Val Gly-Thr-Lys-Pro-Arg-Val 1273 Gly-Thr-Lys-Pro-Phe-Val Gly-Thr-Lys-Pro-Phe-Val Gly-Thr-Lys-Pro-Phe-Val 1274 Gly-Thr-Lys-Pro-Tyr-Val Gly-Thr-Lys-Pro-Tyr-Val Gly-Thr-Lys-Pro-Tyr-Val 1275 Gly-Thr-Lys-Pro-Gly-Val Gly-Thr-Lys-Pro-Gly-Val Gly-Thr-Lys-Pro-Gly-Val 1276 Gly-Thr-Lys-Pro-His-Val Gly-Thr-Lys-Pro-His-Val Gly-Thr-Lys-Pro-His-Val 1277 Gly-Thr-Lys-Pro-Lys-Val Gly-Thr-Lys-Pro-Lys-Val Gly-Thr-Lys-Pro-Lys-Val 1278 Gly-Thr-Lys-Pro-Gly-Val Gly-Thr-Lys-Pro-Gly-Val Gly-Thr-Lys-Pro-Gly-Val 1279 Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Arg- Gly-Thr-Lys-Pro-Gly- 1280 Arg-Val Val Arg-Val Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Phe- Gly-Thr-Lys-Pro-Gly-Phe- 1281 Phe-Val Val Val Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Tyr- Gly-Thr-Lys-Pro-Gly-Tyr- 1282 Tyr-Val Val Val Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-His- Gly-Thr-Lys-Pro-Gly-His- 1283 His-Val Val Val Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Pro- Gly-Thr-Lys-Pro-Gly-Pro- 1284 Pro-Val Val Val Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Lys- Gly-Thr-Lys-Pro-Gly-Lys- 1285 Lys-Val Val Val Gly-Thr-Lys-Pro-Asp-Val Gly-Thr-Lys-Pro-Asp-Val Gly-Thr-Lys-Pro-Asp-Val 1286 Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Arg- Gly-Thr-Lys-Pro-Asp- 1287 Arg-Val Val Arg-Val Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Phe- Gly-Thr-Lys-Pro-Asp- 1288 Phe-Val Val Phe-Val Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Tyr- Gly-Thr-Lys-Pro-Asp- 1289 Tyr-Val Val Tyr-Val Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-His- Gly-Thr-Lys-Pro-Asp-His- 1290 His-Val Val Val Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Pro- Gly-Thr-Lys-Pro-Asp-Pro- 1291 Pro-Val Val Val Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Lys- Gly-Thr-Lys-Pro-Asp- 1292 Lys-Val Val Lys-Val Gly-Thr-Lys-Pro-Trp-Val Gly-Thr-Lys-Pro-Trp-Val Gly-Thr-Lys-Pro-Trp-Val 1293 Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Arg- Gly-Thr-Lys-Pro-Trp-Arg- 1294 Arg-Val Val Val Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Phe- Gly-Thr-Lys-Pro-Trp-Phe- 1295 Phe-Val Val Val Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Tyr- Gly-Thr-Lys-Pro-Trp-Tyr- 1296 Tyr-Val Val Val Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- 1297 Val Val Val Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- 1298 Val Val Val Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Lys- Gly-Thr-Lys-Pro-Trp-Lys- 1299 Lys-Val Val Val Gly-Thr-Lys-Pro-Gln-Val Gly-Thr-Lys-Pro-Gln-Val Gly-Thr-Lys-Pro-Gln-Val 1300 Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Arg- Gly-Thr-Lys-Pro-Gln- 1301 Arg-Val Val Arg-Val Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Phe- Gly-Thr-Lys-Pro-Gln-Phe- 1302 Phe-Val Val Val Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Tyr- Gly-Thr-Lys-Pro-Gln-Tyr- 1303 Tyr-Val Val Val Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-His- Gly-Thr-Lys-Pro-Gln-His- 1304 His-Val Val Val Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Pro- Gly-Thr-Lys-Pro-Gln-Pro- 1305 Pro-Val Val Val Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Lys- Gly-Thr-Lys-Pro-Gln-Lys- 1306 Lys-Val Val Val Gly-Thr-Lys-Pro-Asn-Val Gly-Thr-Lys-Pro-Asn-Val Gly-Thr-Lys-Pro-Asn-Val 1307 Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Arg- Gly-Thr-Lys-Pro-Asn- 1308 Arg-Val Val Arg-Val Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Phe- Gly-Thr-Lys-Pro-Asn- 1309 Phe-Val Val Phe-Val Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Tyr- Gly-Thr-Lys-Pro-Asn- 1310 Tyr-Val Val Tyr-Val Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-His- Gly-Thr-Lys-Pro-Asn-His- 1311 His-Val Val Val Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Pro- Gly-Thr-Lys-Pro-Asn-Pro- 1312 Pro-Val Val Val Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Lys- Gly-Thr-Lys-Pro-Asn- 1313 Lys-Val Val Lys-Val Gly-Thr-Lys-Pro-Tyr-Val Gly-Thr-Lys-Pro-Tyr-Val Gly-Thr-Lys-Pro-Tyr-Val 1314 Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Arg- Gly-Thr-Lys-Pro-Tyr-Arg- 1315 Arg-Val Val Val Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Phe- Gly-Thr-Lys-Pro-Tyr-Phe- 1316 Phe-Val Val Val Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- 1317 Tyr-Val Val Val Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- 1318 Val Val Val

Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- 1319 Val Val Val Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Lys- Gly-Thr-Lys-Pro-Tyr-Lys- 1320 Lys-Val Val Val Gly-Thr-Lys-Pro-Arg-Val Gly-Thr-Lys-Pro-Arg-Val Gly-Thr-Lys-Pro-Arg-Val 1321 Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Arg- Gly-Thr-Lys-Pro-Arg- 1322 Arg-Val Val Arg-Val Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Phe- Gly-Thr-Lys-Pro-Arg- 1323 Phe-Val Val Phe-Val Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Tyr- Gly-Thr-Lys-Pro-Arg-Tyr- 1324 Tyr-Val Val Val Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-His- Gly-Thr-Lys-Pro-Arg-His- 1325 His-Val Val Val Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Pro- Gly-Thr-Lys-Pro-Arg-Pro- 1326 Pro-Val Val Val Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Lys- Gly-Thr-Lys-Pro-Arg- Lys-Val Val Lys-Val 1327 Met-Thr-Lys-Pro-Gly Met-Thr-Lys-Pro-Gly Met-Thr-Lys-Pro-Gly 1328 Met(O)-Thr-Lys-Pro-Gly Met(O)-Thr-Lys-Pro-Gly Met(O)-Thr-Lys-Pro-Gly 1329 Thr-Thr-Lys-Pro-Gly Thr-Thr-Lys-Pro-Gly Thr-Thr-Lys-Pro-Gly 1330 Ala-Thr-Lys-Pro-Gly Ala-Thr-Lys-Pro-Gly Ala-Thr-Lys-Pro-Gly 1331 His-Thr-Lys-Pro-Gly His-Thr-Lys-Pro-Gly His-Thr-Lys-Pro-Gly 1332 Lys-Thr-Lys-Pro-Gly Lys-Thr-Lys-Pro-Gly Lys-Thr-Lys-Pro-Gly 1333 Gly-Thr-Lys-Pro-Gly Gly-Thr-Lys-Pro-Gly Gly-Thr-Lys-Pro-Gly 1334 Thr-Lys-Pro-Arg-Tyr Thr-Lys-Pro-Arg-Tyr Thr-Lys-Pro-Arg-Tyr 1335 Thr-Lys-Pro-Phe-Tyr Thr-Lys-Pro-Phe-Tyr Thr-Lys-Pro-Phe-Tyr 1336 Thr-Lys-Pro-Tyr-Tyr Thr-Lys-Pro-Tyr-Tyr Thr-Lys-Pro-Tyr-Tyr 1337 Thr-Lys-Pro-Gly-Tyr Thr-Lys-Pro-Gly-Tyr Thr-Lys-Pro-Gly-Tyr 1338 Thr-Lys-Pro-His-Tyr Thr-Lys-Pro-His-Tyr Thr-Lys-Pro-His-Tyr 1339 Thr-Lys-Pro-Lys-Tyr Thr-Lys-Pro-Lys-Tyr Thr-Lys-Pro-Lys-Tyr 1340 Thr-Lys-Pro-Gly-Tyr Thr-Lys-Pro-Gly-Tyr Thr-Lys-Pro-Gly-Tyr 1341 Thr-Lys-Pro-Gly-Arg-Tyr Thr-Lys-Pro-Gly-Arg-Tyr Thr-Lys-Pro-Gly-Arg-Tyr 1342 Thr-Lys-Pro-Gly-Phe-Tyr Thr-Lys-Pro-Gly-Phe-Tyr Thr-Lys-Pro-Gly-Phe-Tyr 1343 Thr-Lys-Pro-Gly-Tyr-Tyr Thr-Lys-Pro-Gly-Tyr-Tyr Thr-Lys-Pro-Gly-Tyr-Tyr 1344 Thr-Lys-Pro-Gly-His-Tyr Thr-Lys-Pro-Gly-His-Tyr Thr-Lys-Pro-Gly-His-Tyr 1345 Thr-Lys-Pro-Gly-Pro-Tyr Thr-Lys-Pro-Gly-Pro-Tyr Thr-Lys-Pro-Gly-Pro-Tyr 1346 Thr-Lys-Pro-Gly-Lys-Tyr Thr-Lys-Pro-Gly-Lys-Tyr Thr-Lys-Pro-Gly-Lys-Tyr 1347 Thr-Lys-Pro-Asp-Tyr Thr-Lys-Pro-Asp-Tyr Thr-Lys-Pro-Asp-Tyr 1348 Thr-Lys-Pro-Asp-Arg-Tyr Thr-Lys-Pro-Asp-Arg-Tyr Thr-Lys-Pro-Asp-Arg-Tyr 1349 Thr-Lys-Pro-Asp-Phe-Tyr Thr-Lys-Pro-Asp-Phe-Tyr Thr-Lys-Pro-Asp-Phe-Tyr 1350 Thr-Lys-Pro-Asp-Tyr-Tyr Thr-Lys-Pro-Asp-Tyr-Tyr Thr-Lys-Pro-Asp-Tyr-Tyr 1351 Thr-Lys-Pro-Asp-His-Tyr Thr-Lys-Pro-Asp-His-Tyr Thr-Lys-Pro-Asp-His-Tyr 1352 Thr-Lys-Pro-Asp-Pro-Tyr Thr-Lys-Pro-Asp-Pro-Tyr Thr-Lys-Pro-Asp-Pro-Tyr 1353 Thr-Lys-Pro-Asp-Lys-Tyr Thr-Lys-Pro-Asp-Lys-Tyr Thr-Lys-Pro-Asp-Lys-Tyr 1354 Thr-Lys-Pro-Trp-Tyr Thr-Lys-Pro-Trp-Tyr Thr-Lys-Pro-Trp-Tyr 1355 Thr-Lys-Pro-Trp-Arg-Tyr Thr-Lys-Pro-Trp-Arg-Tyr Thr-Lys-Pro-Trp-Arg-Tyr 1356 Thr-Lys-Pro-Trp-Phe-Tyr Thr-Lys-Pro-Trp-Phe-Tyr Thr-Lys-Pro-Trp-Phe-Tyr 1357 Thr-Lys-Pro-Trp-Tyr-Tyr Thr-Lys-Pro-Trp-Tyr-Tyr Thr-Lys-Pro-Trp-Tyr-Tyr 1358 Thr-Lys-Pro-Trp-His-Tyr Thr-Lys-Pro-Trp-His-Tyr Thr-Lys-Pro-Trp-His-Tyr 1359 Thr-Lys-Pro-Trp-Pro-Tyr Thr-Lys-Pro-Trp-Pro-Tyr Thr-Lys-Pro-Trp-Pro-Tyr 1360 Thr-Lys-Pro-Trp-Lys-Tyr Thr-Lys-Pro-Trp-Lys-Tyr Thr-Lys-Pro-Trp-Lys-Tyr 1361 Thr-Lys-Pro-Gln-Tyr Thr-Lys-Pro-Gln-Tyr Thr-Lys-Pro-Gln-Tyr 1362 Thr-Lys-Pro-Gln-Arg-Tyr Thr-Lys-Pro-Gln-Arg-Tyr Thr-Lys-Pro-Gln-Arg-Tyr 1363 Thr-Lys-Pro-Gln-Phe-Tyr Thr-Lys-Pro-Gln-Phe-Tyr Thr-Lys-Pro-Gln-Phe-Tyr 1364 Thr-Lys-Pro-Gln-Tyr-Tyr Thr-Lys-Pro-Gln-Tyr-Tyr Thr-Lys-Pro-Gln-Tyr-Tyr 1365 Thr-Lys-Pro-Gln-His-Tyr Thr-Lys-Pro-Gln-His-Tyr Thr-Lys-Pro-Gln-His-Tyr 1366 Thr-Lys-Pro-Gln-Pro-Tyr Thr-Lys-Pro-Gln-Pro-Tyr Thr-Lys-Pro-Gln-Pro-Tyr 1367 Thr-Lys-Pro-Gln-Lys-Tyr Thr-Lys-Pro-Gln-Lys-Tyr Thr-Lys-Pro-Gln-Lys-Tyr 1368 Thr-Lys-Pro-Asn-Tyr Thr-Lys-Pro-Asn-Tyr Thr-Lys-Pro-Asn-Tyr 1369 Thr-Lys-Pro-Asn-Arg-Tyr Thr-Lys-Pro-Asn-Arg-Tyr Thr-Lys-Pro-Asn-Arg-Tyr 1370 Thr-Lys-Pro-Asn-Phe-Tyr Thr-Lys-Pro-Asn-Phe-Tyr Thr-Lys-Pro-Asn-Phe-Tyr 1371 Thr-Lys-Pro-Asn-Tyr-Tyr Thr-Lys-Pro-Asn-Tyr-Tyr Thr-Lys-Pro-Asn-Tyr-Tyr 1372 Thr-Lys-Pro-Asn-His-Tyr Thr-Lys-Pro-Asn-His-Tyr Thr-Lys-Pro-Asn-His-Tyr 1373 Thr-Lys-Pro-Asn-Pro-Tyr Thr-Lys-Pro-Asn-Pro-Tyr Thr-Lys-Pro-Asn-Pro-Tyr 1374 Thr-Lys-Pro-Asn-Lys-Tyr Thr-Lys-Pro-Asn-Lys-Tyr Thr-Lys-Pro-Asn-Lys-Tyr 1375 Thr-Lys-Pro-Tyr-Tyr Thr-Lys-Pro-Tyr-Tyr Thr-Lys-Pro-Tyr-Tyr 1376 Thr-Lys-Pro-Tyr-Arg-Tyr Thr-Lys-Pro-Tyr-Arg-Tyr Thr-Lys-Pro-Tyr-Arg-Tyr 1377 Thr-Lys-Pro-Tyr-Phe-Tyr Thr-Lys-Pro-Tyr-Phe-Tyr Thr-Lys-Pro-Tyr-Phe-Tyr 1378 Thr-Lys-Pro-Tyr-Tyr-Tyr Thr-Lys-Pro-Tyr-Tyr-Tyr Thr-Lys-Pro-Tyr-Tyr-Tyr 1379 Thr-Lys-Pro-Tyr-His-Tyr Thr-Lys-Pro-Tyr-His-Tyr Thr-Lys-Pro-Tyr-His-Tyr 1380 Thr-Lys-Pro-Tyr-Pro-Tyr Thr-Lys-Pro-Tyr-Pro-Tyr Thr-Lys-Pro-Tyr-Pro-Tyr 1381 Thr-Lys-Pro-Tyr-Lys-Tyr Thr-Lys-Pro-Tyr-Lys-Tyr Thr-Lys-Pro-Tyr-Lys-Tyr 1382 Thr-Lys-Pro-Arg-Tyr Thr-Lys-Pro-Arg-Tyr Thr-Lys-Pro-Arg-Tyr 1383 Thr-Lys-Pro-Arg-Arg-Tyr Thr-Lys-Pro-Arg-Arg-Tyr Thr-Lys-Pro-Arg-Arg-Tyr 1384 Thr-Lys-Pro-Arg-Phe-Tyr Thr-Lys-Pro-Arg-Phe-Tyr Thr-Lys-Pro-Arg-Phe-Tyr 1385 Thr-Lys-Pro-Arg-Tyr-Tyr Thr-Lys-Pro-Arg-Tyr-Tyr Thr-Lys-Pro-Arg-Tyr-Tyr 1386 Thr-Lys-Pro-Arg-His-Tyr Thr-Lys-Pro-Arg-His-Tyr Thr-Lys-Pro-Arg-His-Tyr 1387 Thr-Lys-Pro-Arg-Pro-Tyr Thr-Lys-Pro-Arg-Pro-Tyr Thr-Lys-Pro-Arg-Pro-Tyr 1388 Thr-Lys-Pro-Arg-Lys-Tyr Thr-Lys-Pro-Arg-Lys-Tyr Thr-Lys-Pro-Arg-Lys-Tyr 1389 Met-Thr-Lys-Pro-Tyr Met-Thr-Lys-Pro-Tyr Met-Thr-Lys-Pro-Tyr 1390 Met-Thr-Lys-Pro-Arg-Tyr Met-Thr-Lys-Pro-Arg-Tyr Met-Thr-Lys-Pro-Arg-Tyr 1391 Met-Thr-Lys-Pro-Phe-Tyr Met-Thr-Lys-Pro-Phe-Tyr Met-Thr-Lys-Pro-Phe-Tyr 1392 Met-Thr-Lys-Pro-Tyr-Tyr Met-Thr-Lys-Pro-Tyr-Tyr Met-Thr-Lys-Pro-Tyr-Tyr 1393 Met-Thr-Lys-Pro-Gly-Tyr Met-Thr-Lys-Pro-Gly-Tyr Met-Thr-Lys-Pro-Gly-Tyr 1394 Met-Thr-Lys-Pro-His-Tyr Met-Thr-Lys-Pro-His-Tyr Met-Thr-Lys-Pro-His-Tyr 1395 Met-Thr-Lys-Pro-Lys-Tyr Met-Thr-Lys-Pro-Lys-Tyr Met-Thr-Lys-Pro-Lys-Tyr 1396 Met-Thr-Lys-Pro-Gly-Tyr Met-Thr-Lys-Pro-Gly-Tyr Met-Thr-Lys-Pro-Gly-Tyr 1397 Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Arg- Met-Thr-Lys-Pro-Gly- 1398 Arg-Tyr Tyr Arg-Tyr Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Phe- Met-Thr-Lys-Pro-Gly- 1399 Phe-Tyr Tyr Phe-Tyr Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Tyr- Met-Thr-Lys-Pro-Gly- 1400 Tyr-Tyr Tyr Tyr-Tyr Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-His- Met-Thr-Lys-Pro-Gly-His- 1401 His-Tyr Tyr Tyr Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Pro- Met-Thr-Lys-Pro-Gly-Pro- 1402 Pro-Tyr Tyr Tyr Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Lys- Met-Thr-Lys-Pro-Gly- 1403 Lys-Tyr Tyr Lys-Tyr Met-Thr-Lys-Pro-Asp-Tyr Met-Thr-Lys-Pro-Asp-Tyr Met-Thr-Lys-Pro-Asp-Tyr 1404 Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Arg- Met-Thr-Lys-Pro-Asp- 1405 Arg-Tyr Tyr Arg-Tyr Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Phe- Met-Thr-Lys-Pro-Asp- 1406 Phe-Tyr Tyr Phe-Tyr Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Tyr- Met-Thr-Lys-Pro-Asp- 1407

Tyr-Tyr Tyr Tyr-Tyr Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-His- Met-Thr-Lys-Pro-Asp- 1408 His-Tyr Tyr His-Tyr Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Pro- Met-Thr-Lys-Pro-Asp- 1409 Pro-Tyr Tyr Pro-Tyr Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Lys- Met-Thr-Lys-Pro-Asp- 1410 Lys-Tyr Tyr Lys-Tyr Met-Thr-Lys-Pro-Trp-Tyr Met-Thr-Lys-Pro-Trp-Tyr Met-Thr-Lys-Pro-Trp-Tyr 1411 Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Arg- Met-Thr-Lys-Pro-Trp- 1412 Arg-Tyr Tyr Arg-Tyr Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Phe- Met-Thr-Lys-Pro-Trp- 1413 Phe-Tyr Tyr Phe-Tyr Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Tyr- Met-Thr-Lys-Pro-Trp-Tyr- 1414 Tyr-Tyr Tyr Tyr Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-His- Met-Thr-Lys-Pro-Trp-His- 1415 His-Tyr Tyr Tyr Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Pro- Met-Thr-Lys-Pro-Trp-Pro- 1416 Pro-Tyr Tyr Tyr Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Lys- Met-Thr-Lys-Pro-Trp- 1417 Lys-Tyr Tyr Lys-Tyr Met-Thr-Lys-Pro-Gln-Tyr Met-Thr-Lys-Pro-Gln-Tyr Met-Thr-Lys-Pro-Gln-Tyr 1418 Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Arg- Met-Thr-Lys-Pro-Gln- 1419 Arg-Tyr Tyr Arg-Tyr Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Phe- Met-Thr-Lys-Pro-Gln- 1420 Phe-Tyr Tyr Phe-Tyr Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Tyr- Met-Thr-Lys-Pro-Gln- 1421 Tyr-Tyr Tyr Tyr-Tyr Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-His- Met-Thr-Lys-Pro-Gln-His- 1422 His-Tyr Tyr Tyr Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Pro- Met-Thr-Lys-Pro-Gln-Pro- 1423 Pro-Tyr Tyr Tyr Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Lys- Met-Thr-Lys-Pro-Gln- 1424 Lys-Tyr Tyr Lys-Tyr Met-Thr-Lys-Pro-Asn-Tyr Met-Thr-Lys-Pro-Asn-Tyr Met-Thr-Lys-Pro-Asn-Tyr 1425 Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Arg- Met-Thr-Lys-Pro-Asn- 1426 Arg-Tyr Tyr Arg-Tyr Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Phe- Met-Thr-Lys-Pro-Asn- 1427 Phe-Tyr Tyr Phe-Tyr Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Tyr- Met-Thr-Lys-Pro-Asn- 1428 Tyr-Tyr Tyr Tyr-Tyr Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-His- Met-Thr-Lys-Pro-Asn- 1429 His-Tyr Tyr His-Tyr Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Pro- Met-Thr-Lys-Pro-Asn- 1430 Pro-Tyr Tyr Pro-Tyr Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Lys- Met-Thr-Lys-Pro-Asn- 1431 Lys-Tyr Tyr Lys-Tyr Met-Thr-Lys-Pro-Tyr-Tyr Met-Thr-Lys-Pro-Tyr-Tyr Met-Thr-Lys-Pro-Tyr-Tyr 1432 Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Arg- Met-Thr-Lys-Pro-Tyr- 1433 Arg-Tyr Tyr Arg-Tyr Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Phe- Met-Thr-Lys-Pro-Tyr- 1434 Phe-Tyr Tyr Phe-Tyr Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- 1435 Tyr-Tyr Tyr Tyr Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-His- Met-Thr-Lys-Pro-Tyr-His- 1436 His-Tyr Tyr Tyr Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Pro- Met-Thr-Lys-Pro-Tyr-Pro- 1437 Pro-Tyr Tyr Tyr Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Lys- Met-Thr-Lys-Pro-Tyr- 1438 Lys-Tyr Tyr Lys-Tyr Met-Thr-Lys-Pro-Arg-Tyr Met-Thr-Lys-Pro-Arg-Tyr Met-Thr-Lys-Pro-Arg-Tyr 1439 Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Arg- Met-Thr-Lys-Pro-Arg- 1440 Arg-Tyr Tyr Arg-Tyr Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Phe- Met-Thr-Lys-Pro-Arg- 1441 Phe-Tyr Tyr Phe-Tyr Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Tyr- Met-Thr-Lys-Pro-Arg- 1442 Tyr-Tyr Tyr Tyr-Tyr Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-His- Met-Thr-Lys-Pro-Arg- 1443 His-Tyr Tyr His-Tyr Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Pro- Met-Thr-Lys-Pro-Arg- 1444 Pro-Tyr Tyr Pro-Tyr Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Lys- Met-Thr-Lys-Pro-Arg- Lys-Tyr Tyr Lys-Tyr 1445 Met(O)-Thr-Lys-Pro-Tyr Met(O)-Thr-Lys-Pro-Tyr Met(O)-Thr-Lys-Pro-Tyr 1446 Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1447 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- 1448 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1449 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1450 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- 1451 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- 1452 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1453 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1454 Arg-Tyr Arg-Tyr Arg-Tyr Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1455 Phe-Tyr Phe-Tyr Phe-Tyr Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1456 Tyr-Tyr Tyr-Tyr Tyr-Tyr Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1457 His-Tyr His-Tyr His-Tyr Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1458 Pro-Tyr Pro-Tyr Pro-Tyr Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1459 Lys-Tyr Lys-Tyr Lys-Tyr Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1460 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1461 Arg-Tyr Arg-Tyr Arg-Tyr Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1462 Phe-Tyr Phe-Tyr Phe-Tyr Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1463 Tyr-Tyr Tyr-Tyr Tyr-Tyr Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1464 His-Tyr His-Tyr His-Tyr Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1465 Pro-Tyr Pro-Tyr Pro-Tyr Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1466 Lys-Tyr Lys-Tyr Lys-Tyr Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1467 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1468 Arg-Tyr Arg-Tyr Arg-Tyr Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1469 Phe-Tyr Phe-Tyr Phe-Tyr Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1470 Tyr-Tyr Tyr-Tyr Tyr-Tyr Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1471 His-Tyr His-Tyr His-Tyr Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1472 Pro-Tyr Pro-Tyr Pro-Tyr Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1473 Lys-Tyr Lys-Tyr Lys-Tyr Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1474 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1475 Arg-Tyr Arg-Tyr Arg-Tyr Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1476 Phe-Tyr Phe-Tyr Phe-Tyr Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1477 Tyr-Tyr Tyr-Tyr Tyr-Tyr Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln-

1478 His-Tyr His-Tyr His-Tyr Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1479 Pro-Tyr Pro-Tyr Pro-Tyr Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1480 Lys-Tyr Lys-Tyr Lys-Tyr Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1481 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1482 Arg-Tyr Arg-Tyr Arg-Tyr Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1483 Phe-Tyr Phe-Tyr Phe-Tyr Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1484 Tyr-Tyr Tyr-Tyr Tyr-Tyr Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1485 His-Tyr His-Tyr His-Tyr Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1486 Pro-Tyr Pro-Tyr Pro-Tyr Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1487 Lys-Tyr Lys-Tyr Lys-Tyr Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1488 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1489 Arg-Tyr Arg-Tyr Arg-Tyr Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1490 Phe-Tyr Phe-Tyr Phe-Tyr Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1491 Tyr-Tyr Tyr-Tyr Tyr-Tyr Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1492 His-Tyr His-Tyr His-Tyr Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1493 Pro-Tyr Pro-Tyr Pro-Tyr Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1494 Lys-Tyr Lys-Tyr Lys-Tyr Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1495 Tyr Tyr Tyr Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1496 Arg-Tyr Arg-Tyr Arg-Tyr Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1497 Phe-Tyr Phe-Tyr Phe-Tyr Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1498 Tyr-Tyr Tyr-Tyr Tyr-Tyr Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1499 His-Tyr His-Tyr His-Tyr Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1500 Pro-Tyr Pro-Tyr Pro-Tyr Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1501 Lys-Tyr Lys-Tyr Lys-Tyr Thr-Thr-Lys-Pro-Tyr Thr-Thr-Lys-Pro-Tyr Thr-Thr-Lys-Pro-Tyr 1502 Thr-Thr-Lys-Pro-Arg-Tyr Thr-Thr-Lys-Pro-Arg-Tyr Thr-Thr-Lys-Pro-Arg-Tyr 1503 Thr-Thr-Lys-Pro-Phe-Tyr Thr-Thr-Lys-Pro-Phe-Tyr Thr-Thr-Lys-Pro-Phe-Tyr 1504 Thr-Thr-Lys-Pro-Tyr-Tyr Thr-Thr-Lys-Pro-Tyr-Tyr Thr-Thr-Lys-Pro-Tyr-Tyr 1505 Thr-Thr-Lys-Pro-Gly-Tyr Thr-Thr-Lys-Pro-Gly-Tyr Thr-Thr-Lys-Pro-Gly-Tyr 1506 Thr-Thr-Lys-Pro-His-Tyr Thr-Thr-Lys-Pro-His-Tyr Thr-Thr-Lys-Pro-His-Tyr 1507 Thr-Thr-Lys-Pro-Lys-Tyr Thr-Thr-Lys-Pro-Lys-Tyr Thr-Thr-Lys-Pro-Lys-Tyr 1508 Thr-Thr-Lys-Pro-Gly-Tyr Thr-Thr-Lys-Pro-Gly-Tyr Thr-Thr-Lys-Pro-Gly-Tyr 1509 Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Arg- Thr-Thr-Lys-Pro-Gly-Arg- 1510 Arg-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Phe- Thr-Thr-Lys-Pro-Gly-Phe- 1511 Phe-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Tyr- Thr-Thr-Lys-Pro-Gly-Tyr- 1512 Tyr-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- 1513 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- 1514 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Lys- Thr-Thr-Lys-Pro-Gly-Lys- 1515 Lys-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Asp-Tyr Thr-Thr-Lys-Pro-Asp-Tyr Thr-Thr-Lys-Pro-Asp-Tyr 1516 Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Arg- Thr-Thr-Lys-Pro-Asp- 1517 Arg-Tyr Tyr Arg-Tyr Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Phe- Thr-Thr-Lys-Pro-Asp- 1518 Phe-Tyr Tyr Phe-Tyr Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Tyr- Thr-Thr-Lys-Pro-Asp-Tyr- 1519 Tyr-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-His- Thr-Thr-Lys-Pro-Asp-His- 1520 His-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Pro- Thr-Thr-Lys-Pro-Asp-Pro- 1521 Pro-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Lys- Thr-Thr-Lys-Pro-Asp- 1522 Lys-Tyr Tyr Lys-Tyr Thr-Thr-Lys-Pro-Trp-Tyr Thr-Thr-Lys-Pro-Trp-Tyr Thr-Thr-Lys-Pro-Trp-Tyr 1523 Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Arg- Thr-Thr-Lys-Pro-Trp-Arg- 1524 Arg-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Phe- Thr-Thr-Lys-Pro-Trp-Phe- 1525 Phe-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- 1526 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- 1527 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- 1528 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Lys- Thr-Thr-Lys-Pro-Trp-Lys- 1529 Lys-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gln-Tyr Thr-Thr-Lys-Pro-Gln-Tyr Thr-Thr-Lys-Pro-Gln-Tyr 1530 Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Arg- Thr-Thr-Lys-Pro-Gln-Arg- 1531 Arg-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Phe- Thr-Thr-Lys-Pro-Gln-Phe- 1532 Phe-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Tyr- Thr-Thr-Lys-Pro-Gln-Tyr- 1533 Tyr-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- 1534 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- 1535 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Lys- Thr-Thr-Lys-Pro-Gin-Lys- 1536 Lys-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Asn-Tyr Thr-Thr-Lys-Pro-Asn-Tyr Thr-Thr-Lys-Pro-Asn-Tyr 1537 Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Arg- Thr-Thr-Lys-Pro-Asn- 1538 Arg-Tyr Tyr Arg-Tyr Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Phe- Thr-Thr-Lys-Pro-Asn- 1539 Phe-Tyr Tyr Phe-Tyr Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Tyr- Thr-Thr-Lys-Pro-Asn-Tyr- 1540 Tyr-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-His- Thr-Thr-Lys-Pro-Asn-His- 1541 His-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Pro- Thr-Thr-Lys-Pro-Asn-Pro- 1542 Pro-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Lys- Thr-Thr-Lys-Pro-Asn- 1543 Lys-Tyr Tyr Lys-Tyr Thr-Thr-Lys-Pro-Tyr-Tyr Thr-Thr-Lys-Pro-Tyr-Tyr Thr-Thr-Lys-Pro-Tyr-Tyr 1544 Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Arg- Thr-Thr-Lys-Pro-Tyr-Arg- 1545 Arg-Tyr Tyr Tyr

Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Phe- Thr-Thr-Lys-Pro-Tyr-Phe- 1546 Phe-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- 1547 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- 1548 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- 1549 Tyr Tyr Tyr Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Lys- Thr-Thr-Lys-Pro-Tyr-Lys- 1550 Lys-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Arg-Tyr Thr-Thr-Lys-Pro-Arg-Tyr Thr-Thr-Lys-Pro-Arg-Tyr 1551 Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Arg- Thr-Thr-Lys-Pro-Arg- 1552 Arg-Tyr Tyr Arg-Tyr Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Phe- Thr-Thr-Lys-Pro-Arg-Phe- 1553 Phe-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Tyr- Thr-Thr-Lys-Pro-Arg-Tyr- 1554 Tyr-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-His- Thr-Thr-Lys-Pro-Arg-His- 1555 His-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Pro- Thr-Thr-Lys-Pro-Arg-Pro- 1556 Pro-Tyr Tyr Tyr Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Lys- Thr-Thr-Lys-Pro-Arg-Lys- 1557 Lys-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Tyr Ala-Thr-Lys-Pro-Tyr Ala-Thr-Lys-Pro-Tyr 1558 Ala-Thr-Lys-Pro-Arg-Tyr Ala-Thr-Lys-Pro-Arg-Tyr Ala-Thr-Lys-Pro-Arg-Tyr 1559 Ala-Thr-Lys-Pro-Phe-Tyr Ala-Thr-Lys-Pro-Phe-Tyr Ala-Thr-Lys-Pro-Phe-Tyr 1560 Ala-Thr-Lys-Pro-Tyr-Tyr Ala-Thr-Lys-Pro-Tyr-Tyr Ala-Thr-Lys-Pro-Tyr-Tyr 1561 Ala-Thr-Lys-Pro-Gly-Tyr Ala-Thr-Lys-Pro-Gly-Tyr Ala-Thr-Lys-Pro-Gly-Tyr 1562 Ala-Thr-Lys-Pro-His-Tyr Ala-Thr-Lys-Pro-His-Tyr Ala-Thr-Lys-Pro-His-Tyr 1563 Ala-Thr-Lys-Pro-Lys-Tyr Ala-Thr-Lys-Pro-Lys-Tyr Ala-Thr-Lys-Pro-Lys-Tyr 1564 Ala-Thr-Lys-Pro-Gly-Tyr Ala-Thr-Lys-Pro-Gly-Tyr Ala-Thr-Lys-Pro-Gly-Tyr 1565 Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Arg- Ala-Thr-Lys-Pro-Gly-Arg- 1566 Arg-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Phe- Ala-Thr-Lys-Pro-Gly-Phe- 1567 Phe-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Tyr- Ala-Thr-Lys-Pro-Gly-Tyr- 1568 Tyr-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- 1569 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- 1570 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Lys- Ala-Thr-Lys-Pro-Gly-Lys- 1571 Lys-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Asp-Tyr Ala-Thr-Lys-Pro-Asp-Tyr Ala-Thr-Lys-Pro-Asp-Tyr 1572 Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Arg- Ala-Thr-Lys-Pro-Asp- 1573 Arg-Tyr Tyr Arg-Tyr Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Phe- Ala-Thr-Lys-Pro-Asp- 1574 Phe-Tyr Tyr Phe-Tyr Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Tyr- Ala-Thr-Lys-Pro-Asp-Tyr- 1575 Tyr-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-His- Ala-Thr-Lys-Pro-Asp-His- 1576 His-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Pro- Ala-Thr-Lys-Pro-Asp-Pro- 1577 Pro-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Lys- Ala-Thr-Lys-Pro-Asp- 1578 Lys-Tyr Tyr Lys-Tyr Ala-Thr-Lys-Pro-Trp-Tyr Ala-Thr-Lys-Pro-Trp-Tyr Ala-Thr-Lys-Pro-Trp-Tyr 1579 Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Arg- Ala-Thr-Lys-Pro-Trp-Arg- 1580 Arg-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Phe- Ala-Thr-Lys-Pro-Trp-Phe- 1581 Phe-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- 1582 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- 1583 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- 1584 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Lys- Ala-Thr-Lys-Pro-Trp-Lys- 1585 Lys-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gln-Tyr Ala-Thr-Lys-Pro-Gln-Tyr Ala-Thr-Lys-Pro-Gln-Tyr 1586 Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Arg- Ala-Thr-Lys-Pro-Gln-Arg- 1587 Arg-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Phe- Ala-Thr-Lys-Pro-Gln-Phe- 1588 Phe-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Tyr- Ala-Thr-Lys-Pro-Gln-Tyr- 1589 Tyr-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- 1590 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- 1591 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Lys- Ala-Thr-Lys-Pro-Gln-Lys- 1592 Lys-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Asn-Tyr Ala-Thr-Lys-Pro-Asn-Tyr Ala-Thr-Lys-Pro-Asn-Tyr 1593 Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Arg- Ala-Thr-Lys-Pro-Asn- 1594 Arg-Tyr Tyr Arg-Tyr Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Phe- Ala-Thr-Lys-Pro-Asn- 1595 Phe-Tyr Tyr Phe-Tyr Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Tyr- Ala-Thr-Lys-Pro-Asn-Tyr- 1596 Tyr-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-His- Ala-Thr-Lys-Pro-Asn-His- 1597 His-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Pro- Ala-Thr-Lys-Pro-Asn-Pro- 1598 Pro-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Lys- Ala-Thr-Lys-Pro-Asn- 1599 Lys-Tyr Tyr Lys-Tyr Ala-Thr-Lys-Pro-Tyr-Tyr Ala-Thr-Lys-Pro-Tyr-Tyr Ala-Thr-Lys-Pro-Tyr-Tyr 1600 Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Arg- Ala-Thr-Lys-Pro-Tyr-Arg- 1601 Arg-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Phe- Ala-Thr-Lys-Pro-Tyr-Phe- 1602 Phe-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- 1603 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- 1604 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- 1605 Tyr Tyr Tyr Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Lys- Ala-Thr-Lys-Pro-Tyr-Lys- 1606 Lys-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Arg-Tyr Ala-Thr-Lys-Pro-Arg-Tyr Ala-Thr-Lys-Pro-Arg-Tyr 1607 Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Arg- Ala-Thr-Lys-Pro-Arg- 1608 Arg-Tyr Tyr Arg-Tyr Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Phe- Ala-Thr-Lys-Pro-Arg-Phe- 1609 Phe-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Tyr- Ala-Thr-Lys-Pro-Arg-Tyr- 1610 Tyr-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-His- Ala-Thr-Lys-Pro-Arg-His- 1611 His-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Pro- Ala-Thr-Lys-Pro-Arg-Pro- 1612 Pro-Tyr Tyr Tyr Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Lys- Ala-Thr-Lys-Pro-Arg-Lys- 1613 Lys-Tyr Tyr Tyr His-Thr-Lys-Pro-Tyr His-Thr-Lys-Pro-Tyr His-Thr-Lys-Pro-Tyr 1614 His-Thr-Lys-Pro-Arg-Tyr His-Thr-Lys-Pro-Arg-Tyr His-Thr-Lys-Pro-Arg-Tyr

1615 His-Thr-Lys-Pro-Phe-Tyr His-Thr-Lys-Pro-Phe-Tyr His-Thr-Lys-Pro-Phe-Tyr 1616 His-Thr-Lys-Pro-Tyr-Tyr His-Thr-Lys-Pro-Tyr-Tyr His-Thr-Lys-Pro-Tyr-Tyr 1617 His-Thr-Lys-Pro-Gly-Tyr His-Thr-Lys-Pro-Gly-Tyr His-Thr-Lys-Pro-Gly-Tyr 1618 His-Thr-Lys-Pro-His-Tyr His-Thr-Lys-Pro-His-Tyr His-Thr-Lys-Pro-His-Tyr 1619 His-Thr-Lys-Pro-Lys-Tyr His-Thr-Lys-Pro-Lys-Tyr His-Thr-Lys-Pro-Lys-Tyr 1620 His-Thr-Lys-Pro-Gly-Tyr His-Thr-Lys-Pro-Gly-Tyr His-Thr-Lys-Pro-Gly-Tyr 1621 His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Arg- His-Thr-Lys-Pro-Gly-Arg- 1622 Arg-Tyr Tyr Tyr His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Phe- His-Thr-Lys-Pro-Gly-Phe- 1623 Phe-Tyr Tyr Tyr His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- 1624 Tyr Tyr Tyr His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- 1625 Tyr Tyr Tyr His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- 1626 Tyr Tyr Tyr His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Lys- His-Thr-Lys-Pro-Gly-Lys- 1627 Lys-Tyr Tyr Tyr His-Thr-Lys-Pro-Asp-Tyr His-Thr-Lys-Pro-Asp-Tyr His-Thr-Lys-Pro-Asp-Tyr 1628 His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Arg- His-Thr-Lys-Pro-Asp- 1629 Arg-Tyr Tyr Arg-Tyr His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Phe- His-Thr-Lys-Pro-Asp-Phe- 1630 Phe-Tyr Tyr Tyr His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Tyr- His-Thr-Lys-Pro-Asp-Tyr- 1631 Tyr-Tyr Tyr Tyr His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-His- His-Thr-Lys-Pro-Asp-His- 1632 His-Tyr Tyr Tyr His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Pro- His-Thr-Lys-Pro-Asp-Pro- 1633 Pro-Tyr Tyr Tyr His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Lys- His-Thr-Lys-Pro-Asp-Lys- 1634 Lys-Tyr Tyr Tyr His-Thr-Lys-Pro-Trp-Tyr His-Thr-Lys-Pro-Trp-Tyr His-Thr-Lys-Pro-Trp-Tyr 1635 His-Thr-Lys-Pro-Trp- His-Thr-Lys-Pro-Trp-Arg- His-Thr-Lys-Pro-Trp-Arg- 1636 Arg-Tyr Tyr Tyr His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- 1637 Tyr Tyr Tyr His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- 1638 Tyr Tyr Tyr His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- 1639 Tyr Tyr Tyr His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- 1640 Tyr Tyr Tyr His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- 1641 Tyr Tyr Tyr His-Thr-Lys-Pro-Gln-Tyr His-Thr-Lys-Pro-Gln-Tyr His-Thr-Lys-Pro-Gln-Tyr 1642 His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Arg- His-Thr-Lys-Pro-Gln-Arg- 1643 Arg-Tyr Tyr Tyr His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Phe- His-Thr-Lys-Pro-Gln-Phe- 1644 Phe-Tyr Tyr Tyr His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- 1645 Tyr Tyr Tyr His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- 1646 Tyr Tyr Tyr His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- 1647 Tyr Tyr Tyr His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Lys- His-Thr-Lys-Pro-Gln-Lys- 1648 Lys-Tyr Tyr Tyr His-Thr-Lys-Pro-Asn-Tyr His-Thr-Lys-Pro-Asn-Tyr His-Thr-Lys-Pro-Asn-Tyr 1649 His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Arg- His-Thr-Lys-Pro-Asn- 1650 Arg-Tyr Tyr Arg-Tyr His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Phe- His-Thr-Lys-Pro-Asn-Phe- 1651 Phe-Tyr Tyr Tyr His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Tyr- His-Thr-Lys-Pro-Asn-Tyr- 1652 Tyr-Tyr Tyr Tyr His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-His- His-Thr-Lys-Pro-Asn-His- 1653 His-Tyr Tyr Tyr His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Pro- His-Thr-Lys-Pro-Asn-Pro- 1654 Pro-Tyr Tyr Tyr His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Lys- His-Thr-Lys-Pro-Asn-Lys- 1655 Lys-Tyr Tyr Tyr His-Thr-Lys-Pro-Tyr-Tyr His-Thr-Lys-Pro-Tyr-Tyr His-Thr-Lys-Pro-Tyr-Tyr 1656 His-Thr-Lys-Pro-Tyr- His-Thr-Lys-Pro-Tyr-Arg- His-Thr-Lys-Pro-Tyr-Arg- 1657 Arg-Tyr Tyr Tyr His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- 1658 Tyr Tyr Tyr His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- 1659 Tyr Tyr Tyr His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- 1660 Tyr Tyr Tyr His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- 1661 Tyr Tyr Tyr His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- Tyr Tyr Tyr 1662 His-Thr-Lys-Pro-Arg-Tyr His-Thr-Lys-Pro-Arg-Tyr His-Thr-Lys-Pro-Arg-Tyr 1663 His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Arg- His-Thr-Lys-Pro-Arg-Arg- 1664 Arg-Tyr Tyr Tyr His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Phe- His-Thr-Lys-Pro-Arg-Phe- 1665 Phe-Tyr Tyr Tyr His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Tyr- His-Thr-Lys-Pro-Arg-Tyr- 1666 Tyr-Tyr Tyr Tyr His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- 1667 Tyr Tyr Tyr His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- 1668 Tyr Tyr Tyr His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Lys- His-Thr-Lys-Pro-Arg-Lys- 1669 Lys-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Tyr Lys-Thr-Lys-Pro-Tyr Lys-Thr-Lys-Pro-Tyr 1670 Lys-Thr-Lys-Pro-Arg-Tyr Lys-Thr-Lys-Pro-Arg-Tyr Lys-Thr-Lys-Pro-Arg-Tyr 1671 Lys-Thr-Lys-Pro-Phe-Tyr Lys-Thr-Lys-Pro-Phe-Tyr Lys-Thr-Lys-Pro-Phe-Tyr 1672 Lys-Thr-Lys-Pro-Tyr-Tyr Lys-Thr-Lys-Pro-Tyr-Tyr Lys-Thr-Lys-Pro-Tyr-Tyr 1673 Lys-Thr-Lys-Pro-Gly-Tyr Lys-Thr-Lys-Pro-Gly-Tyr Lys-Thr-Lys-Pro-Gly-Tyr 1674 Lys-Thr-Lys-Pro-His-Tyr Lys-Thr-Lys-Pro-His-Tyr Lys-Thr-Lys-Pro-His-Tyr 1675 Lys-Thr-Lys-Pro-Lys-Tyr Lys-Thr-Lys-Pro-Lys-Tyr Lys-Thr-Lys-Pro-Lys-Tyr 1676 Lys-Thr-Lys-Pro-Gly-Tyr Lys-Thr-Lys-Pro-Gly-Tyr Lys-Thr-Lys-Pro-Gly-Tyr 1677 Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Arg- Lys-Thr-Lys-Pro-Gly- 1678 Arg-Tyr Tyr Arg-Tyr Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Phe- Lys-Thr-Lys-Pro-Gly-Phe- 1679 Phe-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Tyr- Lys-Thr-Lys-Pro-Gly-Tyr- 1680 Tyr-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-His- Lys-Thr-Lys-Pro-Gly-His- 1681 His-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Pro- Lys-Thr-Lys-Pro-Gly-Pro- 1682 Pro-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Lys- Lys-Thr-Lys-Pro-Gly-Lys- 1683 Lys-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Asp-Tyr Lys-Thr-Lys-Pro-Asp-Tyr Lys-Thr-Lys-Pro-Asp-Tyr

1684 Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Arg- Lys-Thr-Lys-Pro-Asp- 1685 Arg-Tyr Tyr Arg-Tyr Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Phe- Lys-Thr-Lys-Pro-Asp- 1686 Phe-Tyr Tyr Phe-Tyr Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Tyr- Lys-Thr-Lys-Pro-Asp- 1687 Tyr-Tyr Tyr Tyr-Tyr Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-His- Lys-Thr-Lys-Pro-Asp-His- 1688 His-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Pro- Lys-Thr-Lys-Pro-Asp-Pro- 1689 Pro-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Lys- Lys-Thr-Lys-Pro-Asp- 1690 Lys-Tyr Tyr Lys-Tyr Lys-Thr-Lys-Pro-Trp-Tyr Lys-Thr-Lys-Pro-Trp-Tyr Lys-Thr-Lys-Pro-Trp-Tyr 1691 Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Arg- Lys-Thr-Lys-Pro-Trp-Arg- 1692 Arg-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Phe- Lys-Thr-Lys-Pro-Trp-Phe- 1693 Phe-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Tyr- Lys-Thr-Lys-Pro-Trp-Tyr- 1694 Tyr-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- 1695 Tyr Tyr Tyr Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- 1696 Tyr Tyr Tyr Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Lys- Lys-Thr-Lys-Pro-Trp-Lys- 1697 Lys-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Gln-Tyr Lys-Thr-Lys-Pro-Gln-Tyr Lys-Thr-Lys-Pro-Gln-Tyr 1698 Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Arg- Lys-Thr-Lys-Pro-Gln- 1699 Arg-Tyr Tyr Arg-Tyr Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Phe- Lys-Thr-Lys-Pro-Gln-Phe- 1700 Phe-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Tyr- Lys-Thr-Lys-Pro-Gln-Tyr- 1701 Tyr-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-His- Lys-Thr-Lys-Pro-Gln-His- 1702 His-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Pro- Lys-Thr-Lys-Pro-Gln-Pro- 1703 Pro-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Lys- Lys-Thr-Lys-Pro-Gln-Lys- 1704 Lys-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Asn-Tyr Lys-Thr-Lys-Pro-Asn-Tyr Lys-Thr-Lys-Pro-Asn-Tyr 1705 Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Arg- Lys-Thr-Lys-Pro-Asn- 1706 Arg-Tyr Tyr Arg-Tyr Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Phe- Lys-Thr-Lys-Pro-Asn- 1707 Phe-Tyr Tyr Phe-Tyr Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Tyr- Lys-Thr-Lys-Pro-Asn- 1708 Tyr-Tyr Tyr Tyr-Tyr Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-His- Lys-Thr-Lys-Pro-Asn-His- 1709 His-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Pro- Lys-Thr-Lys-Pro-Asn-Pro- 1710 Pro-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Lys- Lys-Thr-Lys-Pro-Asn- 1711 Lys-Tyr Tyr Lys-Tyr Lys-Thr-Lys-Pro-Tyr-Tyr Lys-Thr-Lys-Pro-Tyr-Tyr Lys-Thr-Lys-Pro-Tyr-Tyr 1712 Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Arg- Lys-Thr-Lys-Pro-Tyr-Arg- 1713 Arg-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Phe- Lys-Thr-Lys-Pro-Tyr-Phe- 1714 Phe-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- 1715 Tyr-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- 1716 Tyr Tyr Tyr Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- 1717 Tyr Tyr Tyr Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Lys- Lys-Thr-Lys-Pro-Tyr-Lys- 1718 Lys-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Arg-Tyr Lys-Thr-Lys-Pro-Arg-Tyr Lys-Thr-Lys-Pro-Arg-Tyr 1719 Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Arg- Lys-Thr-Lys-Pro-Arg- 1720 Arg-Tyr Tyr Arg-Tyr Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Phe- Lys-Thr-Lys-Pro-Arg- 1721 Phe-Tyr Tyr Phe-Tyr Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Tyr- Lys-Thr-Lys-Pro-Arg-Tyr- 1722 Tyr-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-His- Lys-Thr-Lys-Pro-Arg-His- 1723 His-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Pro- Lys-Thr-Lys-Pro-Arg-Pro- 1724 Pro-Tyr Tyr Tyr Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Lys- Lys-Thr-Lys-Pro-Arg- 1725 Lys-Tyr Tyr Lys-Tyr Gly-Thr-Lys-Pro-Tyr Gly-Thr-Lys-Pro-Tyr Gly-Thr-Lys-Pro-Tyr 1726 Gly-Thr-Lys-Pro-Arg-Tyr Gly-Thr-Lys-Pro-Arg-Tyr Gly-Thr-Lys-Pro-Arg-Tyr 1727 Gly-Thr-Lys-Pro-Phe-Tyr Gly-Thr-Lys-Pro-Phe-Tyr Gly-Thr-Lys-Pro-Phe-Tyr 1728 Gly-Thr-Lys-Pro-Tyr-Tyr Gly-Thr-Lys-Pro-Tyr-Tyr Gly-Thr-Lys-Pro-Tyr-Tyr 1729 Gly-Thr-Lys-Pro-Gly-Tyr Gly-Thr-Lys-Pro-Gly-Tyr Gly-Thr-Lys-Pro-Gly-Tyr 1730 Gly-Thr-Lys-Pro-His-Tyr Gly-Thr-Lys-Pro-His-Tyr Gly-Thr-Lys-Pro-His-Tyr 1731 Gly-Thr-Lys-Pro-Lys-Tyr Gly-Thr-Lys-Pro-Lys-Tyr Gly-Thr-Lys-Pro-Lys-Tyr 1732 Gly-Thr-Lys-Pro-Gly-Tyr Gly-Thr-Lys-Pro-Gly-Tyr Gly-Thr-Lys-Pro-Gly-Tyr 1733 Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Arg- Gly-Thr-Lys-Pro-Gly- 1734 Arg-Tyr Tyr Arg-Tyr Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Phe- Gly-Thr-Lys-Pro-Gly-Phe- 1735 Phe-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Tyr- Gly-Thr-Lys-Pro-Gly-Tyr- 1736 Tyr-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-His- Gly-Thr-Lys-Pro-Gly-His- 1737 His-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Pro- Gly-Thr-Lys-Pro-Gly-Pro- 1738 Pro-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Lys- Gly-Thr-Lys-Pro-Gly-Lys- 1739 Lys-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Asp-Tyr Gly-Thr-Lys-Pro-Asp-Tyr Gly-Thr-Lys-Pro-Asp-Tyr 1740 Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Arg- Gly-Thr-Lys-Pro-Asp- 1741 Arg-Tyr Tyr Arg-Tyr Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Phe- Gly-Thr-Lys-Pro-Asp- 1742 Phe-Tyr Tyr Phe-Tyr Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Tyr- Gly-Thr-Lys-Pro-Asp- 1743 Tyr-Tyr Tyr Tyr-Tyr Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-His- Gly-Thr-Lys-Pro-Asp-His- 1744 His-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Pro- Gly-Thr-Lys-Pro-Asp-Pro- 1745 Pro-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Lys- Gly-Thr-Lys-Pro-Asp- 1746 Lys-Tyr Tyr Lys-Tyr Gly-Thr-Lys-Pro-Trp-Tyr Gly-Thr-Lys-Pro-Trp-Tyr Gly-Thr-Lys-Pro-Trp-Tyr 1747 Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Arg- Gly-Thr-Lys-Pro-Trp-Arg- 1748 Arg-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Phe- Gly-Thr-Lys-Pro-Trp-Phe- 1749 Phe-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Tyr- Gly-Thr-Lys-Pro-Trp-Tyr- 1750 Tyr-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- 1751 Tyr Tyr Tyr Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- 1752 Tyr Tyr Tyr Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Lys- Gly-Thr-Lys-Pro-Trp-Lys- 1753 Lys-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Gln-Tyr Gly-Thr-Lys-Pro-Gln-Tyr Gly-Thr-Lys-Pro-Gln-Tyr 1754 Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Arg- Gly-Thr-Lys-Pro-Gln- 1755 Arg-Tyr Tyr Arg-Tyr

Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Phe- Gly-Thr-Lys-Pro-Gln-Phe- 1756 Phe-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Tyr- Gly-Thr-Lys-Pro-Gln-Tyr- 1757 Tyr-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-His- Gly-Thr-Lys-Pro-Gln-His- 1758 His-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Pro- Gly-Thr-Lys-Pro-Gln-Pro- 1759 Pro-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Lys- Gly-Thr-Lys-Pro-Gln-Lys- 1760 Lys-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Asn-Tyr Gly-Thr-Lys-Pro-Asn-Tyr Gly-Thr-Lys-Pro-Asn-Tyr 1761 Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Arg- Gly-Thr-Lys-Pro-Asn- 1762 Arg-Tyr Tyr Arg-Tyr Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Phe- Gly-Thr-Lys-Pro-Asn- 1763 Phe-Tyr Tyr Phe-Tyr Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Tyr- Gly-Thr-Lys-Pro-Asn- 1764 Tyr-Tyr Tyr Tyr-Tyr Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-His- Gly-Thr-Lys-Pro-Asn-His- 1765 His-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Pro- Gly-Thr-Lys-Pro-Asn-Pro- 1766 Pro-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Lys- Gly-Thr-Lys-Pro-Asn- 1767 Lys-Tyr Tyr Lys-Tyr Gly-Thr-Lys-Pro-Tyr-Tyr Gly-Thr-Lys-Pro-Tyr-Tyr Gly-Thr-Lys-Pro-Tyr-Tyr 1768 Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Arg- Gly-Thr-Lys-Pro-Tyr-Arg- 1769 Arg-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Phe- Gly-Thr-Lys-Pro-Tyr-Phe- 1770 Phe-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- 1771 Tyr-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- 1772 Tyr Tyr Tyr Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- 1773 Tyr Tyr Tyr Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Lys- Gly-Thr-Lys-Pro-Tyr-Lys- 1774 Lys-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Arg-Tyr Gly-Thr-Lys-Pro-Arg-Tyr Gly-Thr-Lys-Pro-Arg-Tyr 1775 Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Arg- Gly-Thr-Lys-Pro-Arg- 1776 Arg-Tyr Tyr Arg-Tyr Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Phe- Gly-Thr-Lys-Pro-Arg- 1777 Phe-Tyr Tyr Phe-Tyr Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Tyr- Gly-Thr-Lys-Pro-Arg-Tyr- 1778 Tyr-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-His- Gly-Thr-Lys-Pro-Arg-His- 1779 His-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Pro- Gly-Thr-Lys-Pro-Arg-Pro- 1780 Pro-Tyr Tyr Tyr Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Lys- Gly-Thr-Lys-Pro-Arg- 1781 Lys-Tyr Tyr Lys-Tyr Thr-Lys-Pro-Arg-Trp Thr-Lys-Pro-Arg-Trp Thr-Lys-Pro-Arg-Trp 1782 Thr-Lys-Pro-Phe-Trp Thr-Lys-Pro-Phe-Trp Thr-Lys-Pro-Phe-Trp 1783 Thr-Lys-Pro-Tyr-Trp Thr-Lys-Pro-Tyr-Trp Thr-Lys-Pro-Tyr-Trp 1784 Thr-Lys-Pro-Gly-Trp Thr-Lys-Pro-Gly-Trp Thr-Lys-Pro-Gly-Trp 1785 Thr-Lys-Pro-His-Trp Thr-Lys-Pro-His-Trp Thr-Lys-Pro-His-Trp 1786 Thr-Lys-Pro-Lys-Trp Thr-Lys-Pro-Lys-Trp Thr-Lys-Pro-Lys-Trp 1787 Thr-Lys-Pro-Gly-Trp Thr-Lys-Pro-Gly-Trp Thr-Lys-Pro-Gly-Trp 1788 Thr-Lys-Pro-Gly-Arg-Trp Thr-Lys-Pro-Gly-Arg-Trp Thr-Lys-Pro-Gly-Arg-Trp 1789 Thr-Lys-Pro-Gly-Phe-Trp Thr-Lys-Pro-Gly-Phe-Trp Thr-Lys-Pro-Gly-Phe-Trp 1790 Thr-Lys-Pro-Gly-Tyr-Trp Thr-Lys-Pro-Gly-Tyr-Trp Thr-Lys-Pro-Gly-Tyr-Trp 1791 Thr-Lys-Pro-Gly-His-Trp Thr-Lys-Pro-Gly-His-Trp Thr-Lys-Pro-Gly-His-Trp 1792 Thr-Lys-Pro-Gly-Pro-Trp Thr-Lys-Pro-Gly-Pro-Trp Thr-Lys-Pro-Gly-Pro-Trp 1793 Thr-Lys-Pro-Gly-Lys-Trp Thr-Lys-Pro-Gly-Lys-Trp Thr-Lys-Pro-Gly-Lys-Trp 1794 Thr-Lys-Pro-Asp-Trp Thr-Lys-Pro-Asp-Trp Thr-Lys-Pro-Asp-Trp 1795 Thr-Lys-Pro-Asp-Arg-Trp Thr-Lys-Pro-Asp-Arg-Trp Thr-Lys-Pro-Asp-Arg-Trp 1796 Thr-Lys-Pro-Asp-Phe-Trp Thr-Lys-Pro-Asp-Phe-Trp Thr-Lys-Pro-Asp-Phe-Trp 1797 Thr-Lys-Pro-Asp-Tyr-Trp Thr-Lys-Pro-Asp-Tyr-Trp Thr-Lys-Pro-Asp-Tyr-Trp 1798 Thr-Lys-Pro-Asp-His-Trp Thr-Lys-Pro-Asp-His-Trp Thr-Lys-Pro-Asp-His-Trp 1799 Thr-Lys-Pro-Asp-Pro-Trp Thr-Lys-Pro-Asp-Pro-Trp Thr-Lys-Pro-Asp-Pro-Trp 1800 Thr-Lys-Pro-Asp-Lys-Trp Thr-Lys-Pro-Asp-Lys-Trp Thr-Lys-Pro-Asp-Lys-Trp 1801 Thr-Lys-Pro-Trp-Trp Thr-Lys-Pro-Trp-Trp Thr-Lys-Pro-Trp-Trp 1802 Thr-Lys-Pro-Trp-Arg-Trp Thr-Lys-Pro-Trp-Arg-Trp Thr-Lys-Pro-Trp-Arg-Trp 1803 Thr-Lys-Pro-Trp-Phe-Trp Thr-Lys-Pro-Trp-Phe-Trp Thr-Lys-Pro-Trp-Phe-Trp 1804 Thr-Lys-Pro-Trp-Tyr-Trp Thr-Lys-Pro-Trp-Tyr-Trp Thr-Lys-Pro-Trp-Tyr-Trp 1805 Thr-Lys-Pro-Trp-His-Trp Thr-Lys-Pro-Trp-His-Trp Thr-Lys-Pro-Trp-His-Trp 1806 Thr-Lys-Pro-Trp-Pro-Trp Thr-Lys-Pro-Trp-Pro-Trp Thr-Lys-Pro-Trp-Pro-Trp 1807 Thr-Lys-Pro-Trp-Lys-Trp Thr-Lys-Pro-Trp-Lys-Trp Thr-Lys-Pro-Trp-Lys-Trp 1808 Thr-Lys-Pro-Gln-Trp Thr-Lys-Pro-Gln-Trp Thr-Lys-Pro-Gln-Trp 1809 Thr-Lys-Pro-Gln-Arg-Trp Thr-Lys-Pro-Gln-Arg-Trp Thr-Lys-Pro-Gln-Arg-Trp 1810 Thr-Lys-Pro-Gln-Phe-Trp Thr-Lys-Pro-Gln-Phe-Trp Thr-Lys-Pro-Gln-Phe-Trp 1811 Thr-Lys-Pro-Gln-Tyr-Trp Thr-Lys-Pro-Gln-Tyr-Trp Thr-Lys-Pro-Gln-Tyr-Trp 1812 Thr-Lys-Pro-Gln-His-Trp Thr-Lys-Pro-Gln-His-Trp Thr-Lys-Pro-Gln-His-Trp 1813 Thr-Lys-Pro-Gln-Pro-Trp Thr-Lys-Pro-Gln-Pro-Trp Thr-Lys-Pro-Gln-Pro-Trp 1814 Thr-Lys-Pro-Gln-Lys-Trp Thr-Lys-Pro-Gln-Lys-Trp Thr-Lys-Pro-Gln-Lys-Trp 1815 Thr-Lys-Pro-Asn-Trp Thr-Lys-Pro-Asn-Trp Thr-Lys-Pro-Asn-Trp 1816 Thr-Lys-Pro-Asn-Arg-Trp Thr-Lys-Pro-Asn-Arg-Trp Thr-Lys-Pro-Asn-Arg-Trp 1817 Thr-Lys-Pro-Asn-Phe-Trp Thr-Lys-Pro-Asn-Phe-Trp Thr-Lys-Pro-Asn-Phe-Trp 1818 Thr-Lys-Pro-Asn-Tyr-Trp Thr-Lys-Pro-Asn-Tyr-Trp Thr-Lys-Pro-Asn-Tyr-Trp 1819 Thr-Lys-Pro-Asn-His-Trp Thr-Lys-Pro-Asn-His-Trp Thr-Lys-Pro-Asn-His-Trp 1820 Thr-Lys-Pro-Asn-Pro-Trp Thr-Lys-Pro-Asn-Pro-Trp Thr-Lys-Pro-Asn-Pro-Trp 1821 Thr-Lys-Pro-Asn-Lys-Trp Thr-Lys-Pro-Asn-Lys-Trp Thr-Lys-Pro-Asn-Lys-Trp 1822 Thr-Lys-Pro-Tyr-Trp Thr-Lys-Pro-Tyr-Trp Thr-Lys-Pro-Tyr-Trp 1823 Thr-Lys-Pro-Tyr-Arg-Trp Thr-Lys-Pro-Tyr-Arg-Trp Thr-Lys-Pro-Tyr-Arg-Trp 1824 Thr-Lys-Pro-Tyr-Phe-Trp Thr-Lys-Pro-Tyr-Phe-Trp Thr-Lys-Pro-Tyr-Phe-Trp 1825 Thr-Lys-Pro-Tyr-Tyr-Trp Thr-Lys-Pro-Tyr-Tyr-Trp Thr-Lys-Pro-Tyr-Tyr-Trp 1826 Thr-Lys-Pro-Tyr-His-Trp Thr-Lys-Pro-Tyr-His-Trp Thr-Lys-Pro-Tyr-His-Trp 1827 Thr-Lys-Pro-Tyr-Pro-Trp Thr-Lys-Pro-Tyr-Pro-Trp Thr-Lys-Pro-Tyr-Pro-Trp 1828 Thr-Lys-Pro-Tyr-Lys-Trp Thr-Lys-Pro-Tyr-Lys-Trp Thr-Lys-Pro-Tyr-Lys-Trp 1829 Thr-Lys-Pro-Arg-Trp Thr-Lys-Pro-Arg-Trp Thr-Lys-Pro-Arg-Trp 1830 Thr-Lys-Pro-Arg-Arg-Trp Thr-Lys-Pro-Arg-Arg-Trp Thr-Lys-Pro-Arg-Arg-Trp 1831 Thr-Lys-Pro-Arg-Phe-Trp Thr-Lys-Pro-Arg-Phe-Trp Thr-Lys-Pro-Arg-Phe-Trp 1832 Thr-Lys-Pro-Arg-Tyr-Trp Thr-Lys-Pro-Arg-Tyr-Trp Thr-Lys-Pro-Arg-Tyr-Trp 1833 Thr-Lys-Pro-Arg-His-Trp Thr-Lys-Pro-Arg-His-Trp Thr-Lys-Pro-Arg-His-Trp 1834 Thr-Lys-Pro-Arg-Pro-Trp Thr-Lys-Pro-Arg-Pro-Trp Thr-Lys-Pro-Arg-Pro-Trp 1835 Thr-Lys-Pro-Arg-Lys-Trp Thr-Lys-Pro-Arg-Lys-Trp Thr-Lys-Pro-Arg-Lys-Trp 1836 Met-Thr-Lys-Pro-Trp Met-Thr-Lys-Pro-Trp Met-Thr-Lys-Pro-Trp 1837 Met-Thr-Lys-Pro-Arg-Trp Met-Thr-Lys-Pro-Arg-Trp Met-Thr-Lys-Pro-Arg-Trp 1838

Met-Thr-Lys-Pro-Phe-Trp Met-Thr-Lys-Pro-Phe-Trp Met-Thr-Lys-Pro-Phe-Trp 1839 Met-Thr-Lys-Pro-Tyr-Trp Met-Thr-Lys-Pro-Tyr-Trp Met-Thr-Lys-Pro-Tyr-Trp 1840 Met-Thr-Lys-Pro-Gly-Trp Met-Thr-Lys-Pro-Gly-Trp Met-Thr-Lys-Pro-Gly-Trp 1841 Met-Thr-Lys-Pro-His-Trp Met-Thr-Lys-Pro-His-Trp Met-Thr-Lys-Pro-His-Trp 1842 Met-Thr-Lys-Pro-Lys-Trp Met-Thr-Lys-Pro-Lys-Trp Met-Thr-Lys-Pro-Lys-Trp 1843 Met-Thr-Lys-Pro-Gly-Trp Met-Thr-Lys-Pro-Gly-Trp Met-Thr-Lys-Pro-Gly-Trp 1844 Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Arg- Met-Thr-Lys-Pro-Gly- 1845 Arg-Trp Trp Arg-Trp Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Phe- Met-Thr-Lys-Pro-Gly- 1846 Phe-Trp Trp Phe-Trp Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Tyr- Met-Thr-Lys-Pro-Gly- 1847 Tyr-Trp Trp Tyr-Trp Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-His- Met-Thr-Lys-Pro-Gly-His- 1848 His-Trp Trp Trp Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Pro- Met-Thr-Lys-Pro-Gly-Pro- 1849 Pro-Trp Trp Trp Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Lys- Met-Thr-Lys-Pro-Gly- 1850 Lys-Trp Trp Lys-Trp Met-Thr-Lys-Pro-Asp-Trp Met-Thr-Lys-Pro-Asp-Trp Met-Thr-Lys-Pro-Asp-Trp 1851 Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Arg- Met-Thr-Lys-Pro-Asp- 1852 Arg-Trp Trp Arg-Trp Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Phe- Met-Thr-Lys-Pro-Asp- 1853 Phe-Trp Trp Phe-Trp Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Tyr- Met-Thr-Lys-Pro-Asp- 1854 Tyr-Trp Trp Tyr-Trp Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-His- Met-Thr-Lys-Pro-Asp- 1855 His-Trp Trp His-Trp Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Pro- Met-Thr-Lys-Pro-Asp- 1856 Pro-Trp Trp Pro-Trp Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Lys- Met-Thr-Lys-Pro-Asp- 1857 Lys-Trp Trp Lys-Trp Met-Thr-Lys-Pro-Trp-Trp Met-Thr-Lys-Pro-Trp-Trp Met-Thr-Lys-Pro-Trp-Trp 1858 Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Arg- Met-Thr-Lys-Pro-Trp- 1859 Arg-Trp Trp Arg-Trp Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Phe- Met-Thr-Lys-Pro-Trp- 1860 Phe-Trp Trp Phe-Trp Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Tyr- Met-Thr-Lys-Pro-Trp-Tyr- 1861 Tyr-Trp Trp Trp Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-His- Met-Thr-Lys-Pro-Trp-His- 1862 His-Trp Trp Trp Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Pro- Met-Thr-Lys-Pro-Trp-Pro- 1863 Pro-Trp Trp Trp Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Lys- Met-Thr-Lys-Pro-Trp- 1864 Lys-Trp Trp Lys-Trp Met-Thr-Lys-Pro-Gln-Trp Met-Thr-Lys-Pro-Gln-Trp Met-Thr-Lys-Pro-Gln-Trp 1865 Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Arg- Met-Thr-Lys-Pro-Gln- 1866 Arg-Trp Trp Arg-Trp Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Phe- Met-Thr-Lys-Pro-Gln- 1867 Phe-Trp Trp Phe-Trp Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Tyr- Met-Thr-Lys-Pro-Gln- 1868 Tyr-Trp Trp Tyr-Trp Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-His- Met-Thr-Lys-Pro-Gln-His- 1869 His-Trp Trp Trp Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Pro- Met-Thr-Lys-Pro-Gln-Pro- 1870 Pro-Trp Trp Trp Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Lys- Met-Thr-Lys-Pro-Gln- 1871 Lys-Trp Trp Lys-Trp Met-Thr-Lys-Pro-Asn-Trp Met-Thr-Lys-Pro-Asn-Trp Met-Thr-Lys-Pro-Asn-Trp 1872 Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Arg- Met-Thr-Lys-Pro-Asn- 1873 Arg-Trp Trp Arg-Trp Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Phe- Met-Thr-Lys-Pro-Asn- 1874 Phe-Trp Trp Phe-Trp Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Tyr- Met-Thr-Lys-Pro-Asn- 1875 Tyr-Trp Trp Tyr-Trp Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-His- Met-Thr-Lys-Pro-Asn- 1876 His-Trp Trp His-Trp Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Pro- Met-Thr-Lys-Pro-Asn- 1877 Pro-Trp Trp Pro-Trp Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Lys- Met-Thr-Lys-Pro-Asn- 1878 Lys-Trp Trp Lys-Trp Met-Thr-Lys-Pro-Tyr-Trp Met-Thr-Lys-Pro-Tyr-Trp Met-Thr-Lys-Pro-Tyr-Trp 1879 Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Arg- Met-Thr-Lys-Pro-Tyr- 1880 Arg-Trp Trp Arg-Trp Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Phe- Met-Thr-Lys-Pro-Tyr- 1881 Phe-Trp Trp Phe-Trp Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- 1882 Tyr-Trp Trp Trp Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-His- Met-Thr-Lys-Pro-Tyr-His- 1883 His-Trp Trp Trp Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Pro- Met-Thr-Lys-Pro-Tyr-Pro- 1884 Pro-Trp Trp Trp Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Lys- Met-Thr-Lys-Pro-Tyr- 1885 Lys-Trp Trp Lys-Trp Met-Thr-Lys-Pro-Arg-Trp Met-Thr-Lys-Pro-Arg-Trp Met-Thr-Lys-Pro-Arg-Trp 1886 Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Arg- Met-Thr-Lys-Pro-Arg- 1887 Arg-Trp Trp Arg-Trp Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Phe- Met-Thr-Lys-Pro-Arg- 1888 Phe-Trp Trp Phe-Trp Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Tyr- Met-Thr-Lys-Pro-Arg- 1889 Tyr-Trp Trp Tyr-Trp Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-His- Met-Thr-Lys-Pro-Arg- 1890 His-Trp Trp His-Trp Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Pro- Met-Thr-Lys-Pro-Arg- 1891 Pro-Trp Trp Pro-Trp Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Lys- Met-Thr-Lys-Pro-Arg- 1892 Lys-Trp Trp Lys-Trp Met(O)-Thr-Lys-Pro-Trp Met(O)-Thr-Lys-Pro-Trp Met(O)-Thr-Lys-Pro-Trp 1893 Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1894 Trp Trp Trp Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- 1895 Trp Trp Trp Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1896 Trp Trp Trp Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1897 Trp Trp Trp Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- 1898 Trp Trp Trp Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- 1899 Trp Trp Trp Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1900 Trp Trp Trp Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1901 Arg-Trp Arg-Trp Arg-Trp Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1902 Phe-Trp Phe-Trp Phe-Trp Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1903 Tyr-Trp Tyr-Trp Tyr-Trp Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1904 His-Trp His-Trp His-Trp Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1905 Pro-Trp Pro-Trp Pro-Trp Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 1906 Lys-Trp Lys-Trp Lys-Trp Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1907 Trp Trp Trp Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1908 Arg-Trp Arg-Trp Arg-Trp Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1909 Phe-Trp Phe-Trp Phe-Trp Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1910 Tyr-Trp Tyr-Trp Tyr-Trp Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1911 His-Trp His-Trp His-Trp Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 1912 Pro-Trp Pro-Trp Pro-Trp Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp-

1913 Lys-Trp Lys-Trp Lys-Trp Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1914 Trp Trp Trp Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1915 Arg-Trp Arg-Trp Arg-Trp Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1916 Phe-Trp Phe-Trp Phe-Trp Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1917 Tyr-Trp Tyr-Trp Tyr-Trp Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1918 His-Trp His-Trp His-Trp Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1919 Pro-Trp Pro-Trp Pro-Trp Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 1920 Lys-Trp Lys-Trp Lys-Trp Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1921 Trp Trp Trp Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1922 Arg-Trp Arg-Trp Arg-Trp Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1923 Phe-Trp Phe-Trp Phe-Trp Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1924 Tyr-Trp Tyr-Trp Tyr-Trp Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1925 His-Trp His-Trp His-Trp Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1926 Pro-Trp Pro-Trp Pro-Trp Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 1927 Lys-Trp Lys-Trp Lys-Trp Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1928 Trp Trp Trp Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1929 Arg-Trp Arg-Trp Arg-Trp Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1930 Phe-Trp Phe-Trp Phe-Trp Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1931 Tyr-Trp Tyr-Trp Tyr-Trp Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1932 His-Trp His-Trp His-Trp Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1933 Pro-Trp Pro-Trp Pro-Trp Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 1934 Lys-Trp Lys-Trp Lys-Trp Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1935 Trp Trp Trp Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1936 Arg-Trp Arg-Trp Arg-Trp Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1937 Phe-Trp Phe-Trp Phe-Trp Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1938 Tyr-Trp Tyr-Trp Tyr-Trp Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1939 His-Trp His-Trp His-Trp Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1940 Pro-Trp Pro-Trp Pro-Trp Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 1941 Lys-Trp Lys-Trp Lys-Trp Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1942 Trp Trp Trp Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1943 Arg-Trp Arg-Trp Arg-Trp Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1944 Phe-Trp Phe-Trp Phe-Trp Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1945 Tyr-Trp Tyr-Trp Tyr-Trp Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1946 His-Trp His-Trp His-Trp Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1947 Pro-Trp Pro-Trp Pro-Trp Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 1948 Lys-Trp Lys-Trp Lys-Trp Thr-Thr-Lys-Pro-Trp Thr-Thr-Lys-Pro-Trp Thr-Thr-Lys-Pro-Trp 1949 Thr-Thr-Lys-Pro-Arg-Trp Thr-Thr-Lys-Pro-Arg-Trp Thr-Thr-Lys-Pro-Arg-Trp 1950 Thr-Thr-Lys-Pro-Phe-Trp Thr-Thr-Lys-Pro-Phe-Trp Thr-Thr-Lys-Pro-Phe-Trp 1951 Thr-Thr-Lys-Pro-Tyr-Trp Thr-Thr-Lys-Pro-Tyr-Trp Thr-Thr-Lys-Pro-Tyr-Trp 1952 Thr-Thr-Lys-Pro-Gly-Trp Thr-Thr-Lys-Pro-Gly-Trp Thr-Thr-Lys-Pro-Gly-Trp 1953 Thr-Thr-Lys-Pro-His-Trp Thr-Thr-Lys-Pro-His-Trp Thr-Thr-Lys-Pro-His-Trp 1954 Thr-Thr-Lys-Pro-Lys-Trp Thr-Thr-Lys-Pro-Lys-Trp Thr-Thr-Lys-Pro-Lys-Trp 1955 Thr-Thr-Lys-Pro-Gly-Trp Thr-Thr-Lys-Pro-Gly-Trp Thr-Thr-Lys-Pro-Gly-Trp 1956 Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Arg- Thr-Thr-Lys-Pro-Gly-Arg- 1957 Arg-Trp Trp Trp Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Phe- Thr-Thr-Lys-Pro-Gly-Phe- 1958 Phe-Trp Trp Trp Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Tyr- Thr-Thr-Lys-Pro-Gly-Tyr- 1959 Tyr-Trp Trp Trp Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- 1960 Trp Trp Trp Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- 1961 Trp Trp Trp Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Lys- Thr-Thr-Lys-Pro-Gly-Lys- 1962 Lys-Trp Trp Trp Thr-Thr-Lys-Pro-Asp-Trp Thr-Thr-Lys-Pro-Asp-Trp Thr-Thr-Lys-Pro-Asp-Trp 1963 Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Arg- Thr-Thr-Lys-Pro-Asp- 1964 Arg-Trp Trp Arg-Trp Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Phe- Thr-Thr-Lys-Pro-Asp- 1965 Phe-Trp Trp Phe-Trp Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Tyr- Thr-Thr-Lys-Pro-Asp-Tyr- 1966 Tyr-Trp Trp Trp Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-His- Thr-Thr-Lys-Pro-Asp-His- 1967 His-Trp Trp Trp Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Pro- Thr-Thr-Lys-Pro-Asp-Pro- 1968 Pro-Trp Trp Trp Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Lys- Thr-Thr-Lys-Pro-Asp- 1969 Lys-Trp Trp Lys-Trp Thr-Thr-Lys-Pro-Trp-Trp Thr-Thr-Lys-Pro-Trp-Trp Thr-Thr-Lys-Pro-Trp-Trp 1970 Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Arg- Thr-Thr-Lys-Pro-Trp-Arg- 1971 Arg-Trp Trp Trp Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Phe- Thr-Thr-Lys-Pro-Trp-Phe- 1972 Phe-Trp Trp Trp Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- 1973 Trp Trp Trp Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- 1974 Trp Trp Trp Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- 1975 Trp Trp Trp Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Lys- Thr-Thr-Lys-Pro-Trp-Lys- 1976 Lys-Trp Trp Trp Thr-Thr-Lys-Pro-Gln-Trp Thr-Thr-Lys-Pro-Gln-Trp Thr-Thr-Lys-Pro-Gln-Trp 1977 Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Arg- Thr-Thr-Lys-Pro-Gln-Arg- 1978 Arg-Trp Trp Trp Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Phe- Thr-Thr-Lys-Pro-Gln-Phe- 1979 Phe-Trp Trp Trp

Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Tyr- Thr-Thr-Lys-Pro-Gln-Tyr- 1980 Tyr-Trp Trp Trp Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- 1981 Trp Trp Trp Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- 1982 Trp Trp Trp Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Lys- Thr-Thr-Lys-Pro-Gln-Lys- 1983 Lys-Trp Trp Trp Thr-Thr-Lys-Pro-Asn-Trp Thr-Thr-Lys-Pro-Asn-Trp Thr-Thr-Lys-Pro-Asn-Trp 1984 Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Arg- Thr-Thr-Lys-Pro-Asn- 1985 Arg-Trp Trp Arg-Trp Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Phe- Thr-Thr-Lys-Pro-Asn- 1986 Phe-Trp Trp Phe-Trp Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Tyr- Thr-Thr-Lys-Pro-Asn-Tyr- 1987 Tyr-Trp Trp Trp Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-His- Thr-Thr-Lys-Pro-Asn-His- 1988 His-Trp Trp Trp Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Pro- Thr-Thr-Lys-Pro-Asn-Pro- 1989 Pro-Trp Trp Trp Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Lys- Thr-Thr-Lys-Pro-Asn- 1990 Lys-Trp Trp Lys-Trp Thr-Thr-Lys-Pro-Tyr-Trp Thr-Thr-Lys-Pro-Tyr-Trp Thr-Thr-Lys-Pro-Tyr-Trp 1991 Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Arg- Thr-Thr-Lys-Pro-Tyr-Arg- 1992 Arg-Trp Trp Trp Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Phe- Thr-Thr-Lys-Pro-Tyr-Phe- 1993 Phe-Trp Trp Trp Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- 1994 Trp Trp Trp Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- 1995 Trp Trp Trp Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- 1996 Trp Trp Trp Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Lys- Thr-Thr-Lys-Pro-Tyr-Lys- 1997 Lys-Trp Trp Trp Thr-Thr-Lys-Pro-Arg-Trp Thr-Thr-Lys-Pro-Arg-Trp Thr-Thr-Lys-Pro-Arg-Trp 1998 Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Arg- Thr-Thr-Lys-Pro-Arg- 1999 Arg-Trp Trp Arg-Trp Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Phe- Thr-Thr-Lys-Pro-Arg-Phe- 2000 Phe-Trp Trp Trp Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Tyr- Thr-Thr-Lys-Pro-Arg-Tyr- 2001 Tyr-Trp Trp Trp Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-His- Thr-Thr-Lys-Pro-Arg-His- 2002 His-Trp Trp Trp Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Pro- Thr-Thr-Lys-Pro-Arg-Pro- 2003 Pro-Trp Trp Trp Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Lys- Thr-Thr-Lys-Pro-Arg-Lys- 2004 Lys-Trp Trp Trp Ala-Thr-Lys-Pro-Trp Ala-Thr-Lys-Pro-Trp Ala-Thr-Lys-Pro-Trp 2005 Ala-Thr-Lys-Pro-Arg-Trp Ala-Thr-Lys-Pro-Arg-Trp Ala-Thr-Lys-Pro-Arg-Trp 2006 Ala-Thr-Lys-Pro-Phe-Trp Ala-Thr-Lys-Pro-Phe-Trp Ala-Thr-Lys-Pro-Phe-Trp 2007 Ala-Thr-Lys-Pro-Tyr-Trp Ala-Thr-Lys-Pro-Tyr-Trp Ala-Thr-Lys-Pro-Tyr-Trp 2008 Ala-Thr-Lys-Pro-Gly-Trp Ala-Thr-Lys-Pro-Gly-Trp Ala-Thr-Lys-Pro-Gly-Trp 2009 Ala-Thr-Lys-Pro-His-Trp Ala-Thr-Lys-Pro-His-Trp Ala-Thr-Lys-Pro-His-Trp 2010 Ala-Thr-Lys-Pro-Lys-Trp Ala-Thr-Lys-Pro-Lys-Trp Ala-Thr-Lys-Pro-Lys-Trp 2011 Ala-Thr-Lys-Pro-Gly-Trp Ala-Thr-Lys-Pro-Gly-Trp Ala-Thr-Lys-Pro-Gly-Trp 2012 Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Arg- Ala-Thr-Lys-Pro-Gly-Arg- 2013 Arg-Trp Trp Trp Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Phe- Ala-Thr-Lys-Pro-Gly-Phe- 2014 Phe-Trp Trp Trp Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Tyr- Ala-Thr-Lys-Pro-Gly-Tyr- 2015 Tyr-Trp Trp Trp Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- 2016 Trp Trp Trp Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- 2017 Trp Trp Trp Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Lys- Ala-Thr-Lys-Pro-Gly-Lys- 2018 Lys-Trp Trp Trp Ala-Thr-Lys-Pro-Asp-Trp Ala-Thr-Lys-Pro-Asp-Trp Ala-Thr-Lys-Pro-Asp-Trp 2019 Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Arg- Ala-Thr-Lys-Pro-Asp- 2020 Arg-Trp Trp Arg-Trp Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Phe- Ala-Thr-Lys-Pro-Asp- 2021 Phe-Trp Trp Phe-Trp Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Tyr- Ala-Thr-Lys-Pro-Asp-Tyr- 2022 Tyr-Trp Trp Trp Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-His- Ala-Thr-Lys-Pro-Asp-His- 2023 His-Trp Trp Trp Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Pro- Ala-Thr-Lys-Pro-Asp-Pro- 2024 Pro-Trp Trp Trp Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Lys- Ala-Thr-Lys-Pro-Asp- 2025 Lys-Trp Trp Lys-Trp Ala-Thr-Lys-Pro-Trp-Trp Ala-Thr-Lys-Pro-Trp-Trp Ala-Thr-Lys-Pro-Trp-Trp 2026 Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Arg- Ala-Thr-Lys-Pro-Trp-Arg- 2027 Arg-Trp Trp Trp Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Phe- Ala-Thr-Lys-Pro-Trp-Phe- 2028 Phe-Trp Trp Trp Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- 2029 Trp Trp Trp Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- 2030 Trp Trp Trp Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- 2031 Trp Trp Trp Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Lys- Ala-Thr-Lys-Pro-Trp-Lys- 2032 Lys-Trp Trp Trp Ala-Thr-Lys-Pro-Gln-Trp Ala-Thr-Lys-Pro-Gln-Trp Ala-Thr-Lys-Pro-Gln-Trp 2033 Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Arg- Ala-Thr-Lys-Pro-Gln-Arg- 2034 Arg-Trp Trp Trp Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Phe- Ala-Thr-Lys-Pro-Gln-Phe- 2035 Phe-Trp Trp Trp Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Tyr- Ala-Thr-Lys-Pro-Gln-Tyr- 2036 Tyr-Trp Trp Trp Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- 2037 Trp Trp Trp Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- 2038 Trp Trp Trp Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Lys- Ala-Thr-Lys-Pro-Gln-Lys- 2039 Lys-Trp Trp Trp Ala-Thr-Lys-Pro-Asn-Trp Ala-Thr-Lys-Pro-Asn-Trp Ala-Thr-Lys-Pro-Asn-Trp 2040 Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Arg- Ala-Thr-Lys-Pro-Asn- 2041 Arg-Trp Trp Arg-Trp Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Phe- Ala-Thr-Lys-Pro-Asn- 2042 Phe-Trp Trp Phe-Trp Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Tyr- Ala-Thr-Lys-Pro-Asn-Tyr- 2043 Tyr-Trp Trp Trp Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-His- Ala-Thr-Lys-Pro-Asn-His- 2044 His-Trp Trp Trp Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Pro- Ala-Thr-Lys-Pro-Asn-Pro- 2045 Pro-Trp Trp Trp Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Lys- Ala-Thr-Lys-Pro-Asn- 2046 Lys-Trp Trp Lys-Trp Ala-Thr-Lys-Pro-Tyr-Trp Ala-Thr-Lys-Pro-Tyr-Trp Ala-Thr-Lys-Pro-Tyr-Trp 2047 Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Arg- Ala-Thr-Lys-Pro-Tyr-Arg- 2048 Arg-Trp Trp Trp Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Phe- Ala-Thr-Lys-Pro-Tyr-Phe-

2049 Phe-Trp Trp Trp Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- 2050 Trp Trp Trp Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- 2051 Trp Trp Trp Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- 2052 Trp Trp Trp Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Lys- Ala-Thr-Lys-Pro-Tyr-Lys- 2053 Lys-Trp Trp Trp Ala-Thr-Lys-Pro-Arg-Trp Ala-Thr-Lys-Pro-Arg-Trp Ala-Thr-Lys-Pro-Arg-Trp 2054 Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Arg- Ala-Thr-Lys-Pro-Arg- 2055 Arg-Trp Trp Arg-Trp Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Phe- Ala-Thr-Lys-Pro-Arg-Phe- 2056 Phe-Trp Trp Trp Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Tyr- Ala-Thr-Lys-Pro-Arg-Tyr- 2057 Tyr-Trp Trp Trp Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-His- Ala-Thr-Lys-Pro-Arg-His- 2058 His-Trp Trp Trp Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Pro- Ala-Thr-Lys-Pro-Arg-Pro- 2059 Pro-Trp Trp Trp Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Lys- Ala-Thr-Lys-Pro-Arg-Lys- 2060 Lys-Trp Trp Trp His-Thr-Lys-Pro-Trp His-Thr-Lys-Pro-Trp His-Thr-Lys-Pro-Trp 2061 His-Thr-Lys-Pro-Arg-Trp His-Thr-Lys-Pro-Arg-Trp His-Thr-Lys-Pro-Arg-Trp 2062 His-Thr-Lys-Pro-Phe-Trp His-Thr-Lys-Pro-Phe-Trp His-Thr-Lys-Pro-Phe-Trp 2063 His-Thr-Lys-Pro-Tyr-Trp His-Thr-Lys-Pro-Tyr-Trp His-Thr-Lys-Pro-Tyr-Trp 2064 His-Thr-Lys-Pro-Gly-Trp His-Thr-Lys-Pro-Gly-Trp His-Thr-Lys-Pro-Gly-Trp 2065 His-Thr-Lys-Pro-His-Trp His-Thr-Lys-Pro-His-Trp His-Thr-Lys-Pro-His-Trp 2066 His-Thr-Lys-Pro-Lys-Trp His-Thr-Lys-Pro-Lys-Trp His-Thr-Lys-Pro-Lys-Trp 2067 His-Thr-Lys-Pro-Gly-Trp His-Thr-Lys-Pro-Gly-Trp His-Thr-Lys-Pro-Gly-Trp 2068 His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Arg- His-Thr-Lys-Pro-Gly-Arg- 2069 Arg-Trp Trp Trp His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Phe- His-Thr-Lys-Pro-Gly-Phe- 2070 Phe-Trp Trp Trp His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- 2071 Trp Trp Trp His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- 2072 Trp Trp Trp His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- 2073 Trp Trp Trp His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Lys- His-Thr-Lys-Pro-Gly-Lys- 2074 Lys-Trp Trp Trp His-Thr-Lys-Pro-Asp-Trp His-Thr-Lys-Pro-Asp-Trp His-Thr-Lys-Pro-Asp-Trp 2075 His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Arg- His-Thr-Lys-Pro-Asp- 2076 Arg-Trp Trp Arg-Trp His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Phe- His-Thr-Lys-Pro-Asp-Phe- 2077 Phe-Trp Trp Trp His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Tyr- His-Thr-Lys-Pro-Asp-Tyr- 2078 Tyr-Trp Trp Trp His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-His- His-Thr-Lys-Pro-Asp-His- 2079 His-Trp Trp Trp His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Pro- His-Thr-Lys-Pro-Asp-Pro- 2080 Pro-Trp Trp Trp His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Lys- His-Thr-Lys-Pro-Asp-Lys- 2081 Lys-Trp Trp Trp His-Thr-Lys-Pro-Trp-Trp His-Thr-Lys-Pro-Trp-Trp His-Thr-Lys-Pro-Trp-Trp 2082 His-Thr-Lys-Pro-Trp- His-Thr-Lys-Pro-Trp-Arg- His-Thr-Lys-Pro-Trp-Arg- 2083 Arg-Trp Trp Trp His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- 2084 Trp Trp Trp His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- 2085 Trp Trp Trp His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- 2086 Trp Trp Trp His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- 2087 Trp Trp Trp His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- 2088 Trp Trp Trp His-Thr-Lys-Pro-Gln-Trp His-Thr-Lys-Pro-Gln-Trp His-Thr-Lys-Pro-Gln-Trp 2089 His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Arg- His-Thr-Lys-Pro-Gln-Arg- 2090 Arg-Trp Trp Trp His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Phe- His-Thr-Lys-Pro-Gln-Phe- 2091 Phe-Trp Trp Trp His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- 2092 Trp Trp Trp His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- 2093 Trp Trp Trp His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- 2094 Trp Trp Trp His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Lys- His-Thr-Lys-Pro-Gln-Lys- 2095 Lys-Trp Trp Trp His-Thr-Lys-Pro-Asn-Trp His-Thr-Lys-Pro-Asn-Trp His-Thr-Lys-Pro-Asn-Trp 2096 His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Arg- His-Thr-Lys-Pro-Asn- 2097 Arg-Trp Trp Arg-Trp His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Phe- His-Thr-Lys-Pro-Asn-Phe- 2098 Phe-Trp Trp Trp His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Tyr- His-Thr-Lys-Pro-Asn-Tyr- 2099 Tyr-Trp Trp Trp His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-His- His-Thr-Lys-Pro-Asn-His- 2100 His-Trp Trp Trp His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Pro- His-Thr-Lys-Pro-Asn-Pro- 2101 Pro-Trp Trp Trp His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Lys- His-Thr-Lys-Pro-Asn-Lys- 2102 Lys-Trp Trp Trp His-Thr-Lys-Pro-Tyr-Trp His-Thr-Lys-Pro-Tyr-Trp His-Thr-Lys-Pro-Tyr-Trp 2103 His-Thr-Lys-Pro-Tyr- His-Thr-Lys-Pro-Tyr-Arg- His-Thr-Lys-Pro-Tyr-Arg- 2104 Arg-Trp Trp Trp His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- 2105 Trp Trp Trp His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- 2106 Trp Trp Trp His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- 2107 Trp Trp Trp His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- 2108 Trp Trp Trp His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- 2109 Trp Trp Trp His-Thr-Lys-Pro-Arg-Trp His-Thr-Lys-Pro-Arg-Trp His-Thr-Lys-Pro-Arg-Trp 2110 His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Arg- His-Thr-Lys-Pro-Arg-Arg- 2111 Arg-Trp Trp Trp His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Phe- His-Thr-Lys-Pro-Arg-Phe- 2112 Phe-Trp Trp Trp His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Tyr- His-Thr-Lys-Pro-Arg-Tyr- 2113 Tyr-Trp Trp Trp His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- 2114 Trp Trp Trp His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- 2115 Trp Trp Trp His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Lys- His-Thr-Lys-Pro-Arg-Lys- 2116 Lys-Trp Trp Trp

Lys-Thr-Lys-Pro-Trp Lys-Thr-Lys-Pro-Trp Lys-Thr-Lys-Pro-Trp 2117 Lys-Thr-Lys-Pro-Arg-Trp Lys-Thr-Lys-Pro-Arg-Trp Lys-Thr-Lys-Pro-Arg-Trp 2118 Lys-Thr-Lys-Pro-Phe-Trp Lys-Thr-Lys-Pro-Phe-Trp Lys-Thr-Lys-Pro-Phe-Trp 2119 Lys-Thr-Lys-Pro-Tyr-Trp Lys-Thr-Lys-Pro-Tyr-Trp Lys-Thr-Lys-Pro-Tyr-Trp 2120 Lys-Thr-Lys-Pro-Gly-Trp Lys-Thr-Lys-Pro-Gly-Trp Lys-Thr-Lys-Pro-Gly-Trp 2121 Lys-Thr-Lys-Pro-His-Trp Lys-Thr-Lys-Pro-His-Trp Lys-Thr-Lys-Pro-His-Trp 2122 Lys-Thr-Lys-Pro-Lys-Trp Lys-Thr-Lys-Pro-Lys-Trp Lys-Thr-Lys-Pro-Lys-Trp 2123 Lys-Thr-Lys-Pro-Gly-Trp Lys-Thr-Lys-Pro-Gly-Trp Lys-Thr-Lys-Pro-Gly-Trp 2124 Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Arg- Lys-Thr-Lys-Pro-Gly- 2125 Arg-Trp Trp Arg-Trp Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Phe- Lys-Thr-Lys-Pro-Gly-Phe- 2126 Phe-Trp Trp Trp Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Tyr- Lys-Thr-Lys-Pro-Gly-Tyr- 2127 Tyr-Trp Trp Trp Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-His- Lys-Thr-Lys-Pro-Gly-His- 2128 His-Trp Trp Trp Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Pro- Lys-Thr-Lys-Pro-Gly-Pro- 2129 Pro-Trp Trp Trp Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Lys- Lys-Thr-Lys-Pro-Gly-Lys- 2130 Lys-Trp Trp Trp Lys-Thr-Lys-Pro-Asp-Trp Lys-Thr-Lys-Pro-Asp-Trp Lys-Thr-Lys-Pro-Asp-Trp 2131 Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Arg- Lys-Thr-Lys-Pro-Asp- 2132 Arg-Trp Trp Arg-Trp Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Phe- Lys-Thr-Lys-Pro-Asp- 2133 Phe-Trp Trp Phe-Trp Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Tyr- Lys-Thr-Lys-Pro-Asp- 2134 Tyr-Trp Trp Tyr-Trp Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-His- Lys-Thr-Lys-Pro-Asp-His- 2135 His-Trp Trp Trp Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Pro- Lys-Thr-Lys-Pro-Asp-Pro- 2136 Pro-Trp Trp Trp Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Lys- Lys-Thr-Lys-Pro-Asp- 2137 Lys-Trp Trp Lys-Trp Lys-Thr-Lys-ProTrp-Trp Lys-Thr-Lys-Pro-Trp-Trp Lys-Thr-Lys-Pro-Trp-Trp 2138 Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Arg- Lys-Thr-Lys-Pro-Trp-Arg- 2139 Arg-Trp Trp Trp Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Phe- Lys-Thr-Lys-Pro-Trp-Phe- 2140 Phe-Trp Trp Trp Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Tyr- Lys-Thr-Lys-Pro-Trp-Tyr- 2141 Tyr-Trp Trp Trp Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- 2142 Trp Trp Trp Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- 2143 Trp Trp Trp Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Lys- Lys-Thr-Lys-Pro-Trp-Lys- 2144 Lys-Trp Trp Trp Lys-Thr-Lys-Pro-Gln-Trp Lys-Thr-Lys-Pro-Gln-Trp Lys-Thr-Lys-Pro-Gln-Trp 2145 Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Arg- Lys-Thr-Lys-Pro-Gln- 2146 Arg-Trp Trp Arg-Trp Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Phe- Lys-Thr-Lys-Pro-Gln-Phe- 2147 Phe-Trp Trp Trp Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Tyr- Lys-Thr-Lys-Pro-Gln-Tyr- 2148 Tyr-Trp Trp Trp Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-His- Lys-Thr-Lys-Pro-Gln-His- 2149 His-Trp Trp Trp Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Pro- Lys-Thr-Lys-Pro-Gln-Pro- 2150 Pro-Trp Trp Trp Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Lys- Lys-Thr-Lys-Pro-Gln-Lys- 2151 Lys-Trp Trp Trp Lys-Thr-Lys-Pro-Asn-Trp Lys-Thr-Lys-Pro-Asn-Trp Lys-Thr-Lys-Pro-Asn-Trp 2152 Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Arg- Lys-Thr-Lys-Pro-Asn- 2153 Arg-Trp Trp Arg-Trp Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Phe- Lys-Thr-Lys-Pro-Asn- 2154 Phe-Trp Trp Phe-Trp Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Tyr- Lys-Thr-Lys-Pro-Asn- 2155 Tyr-Trp Trp Tyr-Trp Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-His- Lys-Thr-Lys-Pro-Asn-His- 2156 His-Trp Trp Trp Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Pro- Lys-Thr-Lys-Pro-Asn-Pro- 2157 Pro-Trp Trp Trp Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Lys- Lys-Thr-Lys-Pro-Asn- 2158 Lys-Trp Trp Lys-Trp Lys-Thr-Lys-Pro-Tyr-Trp Lys-Thr-Lys-Pro-Tyr-Trp Lys-Thr-Lys-Pro-Tyr-Trp 2159 Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Arg- Lys-Thr-Lys-Pro-Tyr-Arg- 2160 Arg-Trp Trp Trp Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Phe- Lys-Thr-Lys-Pro-Tyr-Phe- 2161 Phe-Trp Trp Trp Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- 2162 Tyr-Trp Trp Trp Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- 2163 Trp Trp Trp Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- 2164 Trp Trp Trp Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Lys- Lys-Thr-Lys-Pro-Tyr-Lys- 2165 Lys-Trp Trp Trp Lys-Thr-Lys-Pro-Arg-Trp Lys-Thr-Lys-Pro-Arg-Trp Lys-Thr-Lys-Pro-Arg-Trp 2166 Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Arg- Lys-Thr-Lys-Pro-Arg- 2167 Arg-Trp Trp Arg-Trp Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Phe- Lys-Thr-Lys-Pro-Arg- 2168 Phe-Trp Trp Phe-Trp Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Tyr- Lys-Thr-Lys-Pro-Arg-Tyr- 2169 Tyr-Trp Trp Trp Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-His- Lys-Thr-Lys-Pro-Arg-His- 2170 His-Trp Trp Trp Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Pro- Lys-Thr-Lys-Pro-Arg-Pro- 2171 Pro-Trp Trp Trp Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Lys- Lys-Thr-Lys-Pro-Arg- 2172 Lys-Trp Trp Lys-Trp Gly-Thr-Lys-Pro-Trp Gly-Thr-Lys-Pro-Trp Gly-Thr-Lys-Pro-Trp 2173 Gly-Thr-Lys-Pro-Arg-Trp Gly-Thr-Lys-Pro-Arg-Trp Gly-Thr-Lys-Pro-Arg-Trp 2174 Gly-Thr-Lys-Pro-Phe-Trp Gly-Thr-Lys-Pro-Phe-Trp Gly-Thr-Lys-Pro-Phe-Trp 2175 Gly-Thr-Lys-Pro-Tyr-Trp Gly-Thr-Lys-Pro-Tyr-Trp Gly-Thr-Lys-Pro-Tyr-Trp 2176 Gly-Thr-Lys-Pro-Gly-Trp Gly-Thr-Lys-Pro-Gly-Trp Gly-Thr-Lys-Pro-Gly-Trp 2177 Gly-Thr-Lys-Pro-His-Trp Gly-Thr-Lys-Pro-His-Trp Gly-Thr-Lys-Pro-His-Trp 2178 Gly-Thr-Lys-Pro-Lys-Trp Gly-Thr-Lys-Pro-Lys-Trp Gly-Thr-Lys-Pro-Lys-Trp 2179 Gly-Thr-Lys-Pro-Gly-Trp Gly-Thr-Lys-Pro-Gly-Trp Gly-Thr-Lys-Pro-Gly-Trp 2180 Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Arg- Gly-Thr-Lys-Pro-Gly- 2181 Arg-Trp Trp Arg-Trp Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Phe- Gly-Thr-Lys-Pro-Gly-Phe- 2182 Phe-Trp Trp Trp Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Tyr- Gly-Thr-Lys-Pro-Gly-Tyr- 2183 Tyr-Trp Trp Trp Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-His- Gly-Thr-Lys-Pro-Gly-His- 2184 His-Trp Trp Trp Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Pro- Gly-Thr-Lys-Pro-Gly-Pro- 2185 Pro-Trp Trp Trp Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Lys- Gly-Thr-Lys-Pro-Gly-Lys- 2186 Lys-Trp Trp Trp Gly-Thr-Lys-Pro-Asp-Trp Gly-Thr-Lys-Pro-Asp-Trp Gly-Thr-Lys-Pro-Asp-Trp 2187 Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Arg- Gly-Thr-Lys-Pro-Asp- 2188 Arg-Trp Trp Arg-Trp Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Phe- Gly-Thr-Lys-Pro-Asp- 2189 Phe-Trp Trp Phe-Trp

Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Tyr- Gly-Thr-Lys-Pro-Asp- 2190 Tyr-Trp Trp Tyr-Trp Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-His- Gly-Thr-Lys-Pro-Asp-His- 2191 His-Trp Trp Trp Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Pro- Gly-Thr-Lys-Pro-Asp-Pro- 2192 Pro-Trp Trp Trp Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Lys- Gly-Thr-Lys-Pro-Asp- 2193 Lys-Trp Trp Lys-Trp Gly-Thr-Lys-Pro-Trp-Trp Gly-Thr-Lys-Pro-Trp-Trp Gly-Thr-Lys-Pro-Trp-Trp 2194 Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Arg- Gly-Thr-Lys-Pro-Trp-Arg- 2195 Arg-Trp Trp Trp Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Phe- Gly-Thr-Lys-Pro-Trp-Phe- 2196 Phe-Trp Trp Trp Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Tyr- Gly-Thr-Lys-Pro-Trp-Tyr- 2197 Tyr-Trp Trp Trp Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- 2198 Trp Trp Trp Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- 2199 Trp Trp Trp Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Lys- Gly-Thr-Lys-Pro-Trp-Lys- 2200 Lys-Trp Trp Trp Gly-Thr-Lys-Pro-Gln-Trp Gly-Thr-Lys-Pro-Gln-Trp Gly-Thr-Lys-Pro-Gln-Trp 2201 Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Arg- Gly-Thr-Lys-Pro-Gln- 2202 Arg-Trp Trp Arg-Trp Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Phe- Gly-Thr-Lys-Pro-Gln-Phe- 2203 Phe-Trp Trp Trp Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Tyr- Gly-Thr-Lys-Pro-Gln-Tyr- 2204 Tyr-Trp Trp Trp Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-His- Gly-Thr-Lys-Pro-Gln-His- 2205 His-Trp Trp Trp Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Pro- Gly-Thr-Lys-Pro-Gln-Pro- 2206 Pro-Trp Trp Trp Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Lys- Gly-Thr-Lys-Pro-Gln-Lys- 2207 Lys-Trp Trp Trp Gly-Thr-Lys-Pro-Asn-Trp Gly-Thr-Lys-Pro-Asn-Trp Gly-Thr-Lys-Pro-Asn-Trp 2208 Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Arg- Gly-Thr-Lys-Pro-Asn- 2209 Arg-Trp Trp Arg-Trp Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Phe- Gly-Thr-Lys-Pro-Asn- 2210 Phe-Trp Trp Phe-Trp Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Tyr- Gly-Thr-Lys-Pro-Asn- 2211 Tyr-Trp Trp Tyr-Trp Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-His- Gly-Thr-Lys-Pro-Asn-His- 2212 His-Trp Trp Trp Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Pro- Gly-Thr-Lys-Pro-Asn-Pro- 2213 Pro-Trp Trp Trp Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Lys- Gly-Thr-Lys-Pro-Asn- 2214 Lys-Trp Trp Lys-Trp Gly-Thr-Lys-Pro-Tyr-Trp Gly-Thr-Lys-Pro-Tyr-Trp Gly-Thr-Lys-Pro-Tyr-Trp 2215 Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Arg- Gly-Thr-Lys-Pro-Tyr-Arg- 2216 Arg-Trp Trp Trp Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Phe- Gly-Thr-Lys-Pro-Tyr-Phe- 2217 Phe-Trp Trp Trp Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- 2218 Tyr-Trp Trp Trp Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- 2219 Trp Trp Trp Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- 2220 Trp Trp Trp Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Lys- Gly-Thr-Lys-Pro-Tyr-Lys- 2221 Lys-Trp Trp Trp Gly-Thr-Lys-Pro-Arg-Trp Gly-Thr-Lys-Pro-Arg-Trp Gly-Thr-Lys-Pro-Arg-Trp 2222 Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Arg- Gly-Thr-Lys-Pro-Arg- 2223 Arg-Trp Trp Arg-Trp Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Phe- Gly-Thr-Lys-Pro-Arg- 2224 Phe-Trp Trp Phe-Trp Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Tyr- Gly-Thr-Lys-Pro-Arg-Tyr- 2225 Tyr-Trp Trp Trp Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-His- Gly-Thr-Lys-Pro-Arg-His- 2226 His-Trp Trp Trp Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Pro- Gly-Thr-Lys-Pro-Arg-Pro- 2227 Pro-Trp Trp Trp Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Lys- Gly-Thr-Lys-Pro-Arg- 2228 Lys-Trp Trp Lys-Trp Thr-Lys-Pro-Arg-Phe Thr-Lys-Pro-Arg-Phe Thr-Lys-Pro-Arg-Phe 2229 Thr-Lys-Pro-Phe-Phe Thr-Lys-Pro-Phe-Phe Thr-Lys-Pro-Phe-Phe 2230 Thr-Lys-Pro-Tyr-Phe Thr-Lys-Pro-Tyr-Phe Thr-Lys-Pro-Tyr-Phe 2231 Thr-Lys-Pro-Gly-Phe Thr-Lys-Pro-Gly-Phe Thr-Lys-Pro-Gly-Phe 2232 Thr-Lys-Pro-His-Phe Thr-Lys-Pro-His-Phe Thr-Lys-Pro-His-Phe 2233 Thr-Lys-Pro-Lys-Phe Thr-Lys-Pro-Lys-Phe Thr-Lys-Pro-Lys-Phe 2234 Thr-Lys-Pro-Gly-Phe Thr-Lys-Pro-Gly-Phe Thr-Lys-Pro-Gly-Phe 2235 Thr-Lys-Pro-Gly-Arg-Phe Thr-Lys-Pro-Gly-Arg-Phe Thr-Lys-Pro-Gly-Arg-Phe 2236 Thr-Lys-Pro-Gly-Phe-Phe Thr-Lys-Pro-Gly-Phe-Phe Thr-Lys-Pro-Gly-Phe-Phe 2237 Thr-Lys-Pro-Gly-Tyr-Phe Thr-Lys-Pro-Gly-Tyr-Phe Thr-Lys-Pro-Gly-Tyr-Phe 2238 Thr-Lys-Pro-Gly-His-Phe Thr-Lys-Pro-Gly-His-Phe Thr-Lys-Pro-Gly-His-Phe 2239 Thr-Lys-Pro-Gly-Pro-Phe Thr-Lys-Pro-Gly-Pro-Phe Thr-Lys-Pro-Gly-Pro-Phe 2240 Thr-Lys-Pro-Gly-Lys-Phe Thr-Lys-Pro-Gly-Lys-Phe Thr-Lys-Pro-Gly-Lys-Phe 2241 Thr-Lys-Pro-Asp-Phe Thr-Lys-Pro-Asp-Phe Thr-Lys-Pro-Asp-Phe 2242 Thr-Lys-Pro-Asp-Arg-Phe Thr-Lys-Pro-Asp-Arg-Phe Thr-Lys-Pro-Asp-Arg-Phe 2243 Thr-Lys-Pro-Asp-Phe-Phe Thr-Lys-Pro-Asp-Phe-Phe Thr-Lys-Pro-Asp-Phe-Phe 2244 Thr-Lys-Pro-Asp-Tyr-Phe Thr-Lys-Pro-Asp-Tyr-Phe Thr-Lys-Pro-Asp-Tyr-Phe 2245 Thr-Lys-Pro-Asp-His-Phe Thr-Lys-Pro-Asp-His-Phe Thr-Lys-Pro-Asp-His-Phe 2246 Thr-Lys-Pro-Asp-Pro-Phe Thr-Lys-Pro-Asp-Pro-Phe Thr-Lys-Pro-Asp-Pro-Phe 2247 Thr-Lys-Pro-Asp-Lys-Phe Thr-Lys-Pro-Asp-Lys-Phe Thr-Lys-Pro-Asp-Lys-Phe 2248 Thr-Lys-Pro-Trp-Phe Thr-Lys-Pro-Trp-Phe Thr-Lys-Pro-Trp-Phe 2249 Thr-Lys-Pro-Trp-Arg-Phe Thr-Lys-Pro-Trp-Arg-Phe Thr-Lys-Pro-Trp-Arg-Phe 2250 Thr-Lys-Pro-Trp-Phe-Phe Thr-Lys-Pro-Trp-Phe-Phe Thr-Lys-Pro-Trp-Phe-Phe 2251 Thr-Lys-Pro-Trp-Tyr-Phe Thr-Lys-Pro-Trp-Tyr-Phe Thr-Lys-Pro-Trp-Tyr-Phe 2252 Thr-Lys-Pro-Trp-His-Phe Thr-Lys-Pro-Trp-His-Phe Thr-Lys-Pro-Trp-His-Phe 2253 Thr-Lys-Pro-Trp-Pro-Phe Thr-Lys-Pro-Trp-Pro-Phe Thr-Lys-Pro-Trp-Pro-Phe 2254 Thr-Lys-Pro-Trp-Lys-Phe Thr-Lys-Pro-Trp-Lys-Phe Thr-Lys-Pro-Trp-Lys-Phe 2255 Thr-Lys-Pro-Gln-Phe Thr-Lys-Pro-Gln-Phe Thr-Lys-Pro-Gln-Phe 2256 Thr-Lys-Pro-Gln-Arg-Phe Thr-Lys-Pro-Gln-Arg-Phe Thr-Lys-Pro-Gln-Arg-Phe 2257 Thr-Lys-Pro-Gln-Phe-Phe Thr-Lys-Pro-Gln-Phe-Phe Thr-Lys-Pro-Gln-Phe-Phe 2258 Thr-Lys-Pro-Gln-Tyr-Phe Thr-Lys-Pro-Gln-Tyr-Phe Thr-Lys-Pro-Gln-Tyr-Phe 2259 Thr-Lys-Pro-Gln-His-Phe Thr-Lys-Pro-Gln-His-Phe Thr-Lys-Pro-Gln-His-Phe 2260 Thr-Lys-Pro-Gln-Pro-Phe Thr-Lys-Pro-Gln-Pro-Phe Thr-Lys-Pro-Gln-Pro-Phe 2261 Thr-Lys-Pro-Gln-Lys-Phe Thr-Lys-Pro-Gln-Lys-Phe Thr-Lys-Pro-Gln-Lys-Phe 2262 Thr-Lys-Pro-Asn-Phe Thr-Lys-Pro-Asn-Phe Thr-Lys-Pro-Asn-Phe 2263 Thr-Lys-Pro-Asn-Arg-Phe Thr-Lys-Pro-Asn-Arg-Phe Thr-Lys-Pro-Asn-Arg-Phe 2264 Thr-Lys-Pro-Asn-Phe-Phe Thr-Lys-Pro-Asn-Phe-Phe Thr-Lys-Pro-Asn-Phe-Phe 2265 Thr-Lys-Pro-Asn-Tyr-Phe Thr-Lys-Pro-Asn-Tyr-Phe Thr-Lys-Pro-Asn-Tyr-Phe 2266 Thr-Lys-Pro-Asn-His-Phe Thr-Lys-Pro-Asn-His-Phe Thr-Lys-Pro-Asn-His-Phe 2267 Thr-Lys-Pro-Asn-Pro-Phe Thr-Lys-Pro-Asn-Pro-Phe Thr-Lys-Pro-Asn-Pro-Phe 2268

Thr-Lys-Pro-Asn-Lys-Phe Thr-Lys-Pro-Asn-Lys-Phe Thr-Lys-Pro-Asn-Lys-Phe 2269 Thr-Lys-Pro-Tyr-Phe Thr-Lys-Pro-Tyr-Phe Thr-Lys-Pro-Tyr-Phe 2270 Thr-Lys-Pro-Tyr-Arg-Phe Thr-Lys-Pro-Tyr-Arg-Phe Thr-Lys-Pro-Tyr-Arg-Phe 2271 Thr-Lys-Pro-Tyr-Phe-Phe Thr-Lys-Pro-Tyr-Phe-Phe Thr-Lys-Pro-Tyr-Phe-Phe 2272 Thr-Lys-Pro-Tyr-Tyr-Phe Thr-Lys-Pro-Tyr-Tyr-Phe Thr-Lys-Pro-Tyr-Tyr-Phe 2273 Thr-Lys-Pro-Tyr-His-Phe Thr-Lys-Pro-Tyr-His-Phe Thr-Lys-Pro-Tyr-His-Phe 2274 Thr-Lys-Pro-Tyr-Pro-Phe Thr-Lys-Pro-Tyr-Pro-Phe Thr-Lys-Pro-Tyr-Pro-Phe 2275 Thr-Lys-Pro-Tyr-Lys-Phe Thr-Lys-Pro-Tyr-Lys-Phe Thr-Lys-Pro-Tyr-Lys-Phe 2276 Thr-Lys-Pro-Arg-Phe Thr-Lys-Pro-Arg-Phe Thr-Lys-Pro-Arg-Phe 2277 Thr-Lys-Pro-Arg-Arg-Phe Thr-Lys-Pro-Arg-Arg-Phe Thr-Lys-Pro-Arg-Arg-Phe 2278 Thr-Lys-Pro-Arg-Phe-Phe Thr-Lys-Pro-Arg-Phe-Phe Thr-Lys-Pro-Arg-Phe-Phe 2279 Thr-Lys-Pro-Arg-Tyr-Phe Thr-Lys-Pro-Arg-Tyr-Phe Thr-Lys-Pro-Arg-Tyr-Phe 2280 Thr-Lys-Pro-Arg-His-Phe Thr-Lys-Pro-Arg-His-Phe Thr-Lys-Pro-Arg-His-Phe 2281 Thr-Lys-Pro-Arg-Pro-Phe Thr-Lys-Pro-Arg-Pro-Phe Thr-Lys-Pro-Arg-Pro-Phe 7 Thr-Lys-Pro-Arg-Lys-Phe Thr-Lys-Pro-Arg-Lys-Phe Thr-Lys-Pro-Arg-Lys-Phe 2282 Met-Thr-Lys-Pro-Phe Met-Thr-Lys-Pro-Phe Met-Thr-Lys-Pro-Phe 2283 Met-Thr-Lys-Pro-Arg-Phe Met-Thr-Lys-Pro-Arg-Phe Met-Thr-Lys-Pro-Arg-Phe 2284 Met-Thr-Lys-Pro-Phe-Phe Met-Thr-Lys-Pro-Phe-Phe Met-Thr-Lys-Pro-Phe-Phe 2285 Met-Thr-Lys-Pro-Tyr-Phe Met-Thr-Lys-Pro-Tyr-Phe Met-Thr-Lys-Pro-Tyr-Phe 2286 Met-Thr-Lys-Pro-Gly-Phe Met-Thr-Lys-Pro-Gly-Phe Met-Thr-Lys-Pro-Gly-Phe 2287 Met-Thr-Lys-Pro-His-Phe Met-Thr-Lys-Pro-His-Phe Met-Thr-Lys-Pro-His-Phe 2288 Met-Thr-Lys-Pro-Lys-Phe Met-Thr-Lys-Pro-Lys-Phe Met-Thr-Lys-Pro-Lys-Phe 2289 Met-Thr-Lys-Pro-Gly-Phe Met-Thr-Lys-Pro-Gly-Phe Met-Thr-Lys-Pro-Gly-Phe 2290 Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Arg- Met-Thr-Lys-Pro-Gly- 2291 Arg-Phe Phe Arg-Phe Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Phe- Met-Thr-Lys-Pro-Gly- 2292 Phe-Phe Phe Phe-Phe Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Tyr- Met-Thr-Lys-Pro-Gly- 2293 Tyr-Phe Phe Tyr-Phe Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-His- Met-Thr-Lys-Pro-Gly-His- 2294 His-Phe Phe Phe Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Pro- Met-Thr-Lys-Pro-Gly-Pro- 2295 Pro-Phe Phe Phe Met-Thr-Lys-Pro-Gly- Met-Thr-Lys-Pro-Gly-Lys- Met-Thr-Lys-Pro-Gly- 2296 Lys-Phe Phe Lys-Phe Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Phe Met-Thr-Lys-Pro-Asp-Phe 2297 Phe Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Arg- Met-Thr-Lys-Pro-Asp- 2298 Arg-Phe Phe Arg-Phe Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Phe- Met-Thr-Lys-Pro-Asp- 2299 Phe-Phe Phe Phe-Phe Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Tyr- Met-Thr-Lys-Pro-Asp- 2300 Tyr-Phe Phe Tyr-Phe Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-His- Met-Thr-Lys-Pro-Asp- 2301 His-Phe Phe His-Phe Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Pro- Met-Thr-Lys-Pro-Asp- 2302 Pro-Phe Phe Pro-Phe Met-Thr-Lys-Pro-Asp- Met-Thr-Lys-Pro-Asp-Lys- Met-Thr-Lys-Pro-Asp- 2303 Lys-Phe Phe Lys-Phe Met-Thr-Lys-Pro-Trp-Phe Met-Thr-Lys-Pro-Trp-Phe Met-Thr-Lys-Pro-Trp-Phe 2304 Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Arg- Met-Thr-Lys-Pro-Trp- 2305 Arg-Phe Phe Arg-Phe Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Phe- Met-Thr-Lys-Pro-Trp- 2306 Phe-Phe Phe Phe-Phe Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Tyr- Met-Thr-Lys-Pro-Trp-Tyr- 2307 Tyr-Phe Phe Phe Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-His- Met-Thr-Lys-Pro-Trp-His- 2308 His-Phe Phe Phe Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Pro- Met-Thr-Lys-Pro-Trp-Pro- 2309 Pro-Phe Phe Phe Met-Thr-Lys-Pro-Trp- Met-Thr-Lys-Pro-Trp-Lys- Met-Thr-Lys-Pro-Trp- 2310 Lys-Phe Phe Lys-Phe Met-Thr-Lys-Pro-Gln-Phe Met-Thr-Lys-Pro-Gln-Phe Met-Thr-Lys-Pro-Gln-Phe 2311 Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Arg- Met-Thr-Lys-Pro-Gln- 2312 Arg-Phe Phe Arg-Phe Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Phe- Met-Thr-Lys-Pro-Gln- 2313 Phe-Phe Phe Phe-Phe Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Tyr- Met-Thr-Lys-Pro-Gln- 2314 Tyr-Phe Phe Tyr-Phe Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-His- Met-Thr-Lys-Pro-Gln-His- 2315 His-Phe Phe Phe Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Pro- Met-Thr-Lys-Pro-Gln-Pro- 2316 Pro-Phe Phe Phe Met-Thr-Lys-Pro-Gln- Met-Thr-Lys-Pro-Gln-Lys- Met-Thr-Lys-Pro-Gln- 2317 Lys-Phe Phe Lys-Phe Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Phe Met-Thr-Lys-Pro-Asn-Phe 2318 Phe Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Arg- Met-Thr-Lys-Pro-Asn- 2319 Arg-Phe Phe Arg-Phe Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Phe- Met-Thr-Lys-Pro-Asn- 2320 Phe-Phe Phe Phe-Phe Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Tyr- Met-Thr-Lys-Pro-Asn- 2321 Tyr-Phe Phe Tyr-Phe Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-His- Met-Thr-Lys-Pro-Asn- 2322 His-Phe Phe His-Phe Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Pro- Met-Thr-Lys-Pro-Asn- 2323 Pro-Phe Phe Pro-Phe Met-Thr-Lys-Pro-Asn- Met-Thr-Lys-Pro-Asn-Lys- Met-Thr-Lys-Pro-Asn- 2324 Lys-Phe Phe Lys-Phe Met-Thr-Lys-Pro-Tyr-Phe Met-Thr-Lys-Pro-Tyr-Phe Met-Thr-Lys-Pro-Tyr-Phe 2325 Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Arg- Met-Thr-Lys-Pro-Tyr- 2326 Arg-Phe Phe Arg-Phe Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Phe- Met-Thr-Lys-Pro-Tyr- 2327 Phe-Phe Phe Phe-Phe Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- Met-Thr-Lys-Pro-Tyr-Tyr- 2328 Tyr-Phe Phe Phe Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-His- Met-Thr-Lys-Pro-Tyr-His- 2329 His-Phe Phe Phe Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Pro- Met-Thr-Lys-Pro-Tyr-Pro- 2330 Pro-Phe Phe Phe Met-Thr-Lys-Pro-Tyr- Met-Thr-Lys-Pro-Tyr-Lys- Met-Thr-Lys-Pro-Tyr- 2331 Lys-Phe Phe Lys-Phe Met-Thr-Lys-Pro-Arg-Phe Met-Thr-Lys-Pro-Arg-Phe Met-Thr-Lys-Pro-Arg-Phe 2332 Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Arg- Met-Thr-Lys-Pro-Arg- 2333 Arg-Phe Phe Arg-Phe Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Phe- Met-Thr-Lys-Pro-Arg- 2334 Phe-Phe Phe Phe-Phe Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Tyr- Met-Thr-Lys-Pro-Arg- 2335 Tyr-Phe Phe Tyr-Phe Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-His- Met-Thr-Lys-Pro-Arg- 2336 His-Phe Phe His-Phe Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Pro- Met-Thr-Lys-Pro-Arg- 2337 Pro-Phe Phe Pro-Phe Met-Thr-Lys-Pro-Arg- Met-Thr-Lys-Pro-Arg-Lys- Met-Thr-Lys-Pro-Arg- 2338 Lys-Phe Phe Lys-Phe Met(O)-Thr-Lys-Pro-Phe Met(O)-Thr-Lys-Pro-Phe Met(O)-Thr-Lys-Pro-Phe 2339 Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 2340 Phe Phe Phe Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- Met(O)-Thr-Lys-Pro-Phe- 2341 Phe Phe Phe Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 2342 Phe Phe Phe Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 2343 Phe Phe Phe Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- Met(O)-Thr-Lys-Pro-His- 2344 Phe Phe Phe Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- Met(O)-Thr-Lys-Pro-Lys- 2345 Phe Phe Phe Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 2346 Phe Phe Phe Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 2347

Arg-Phe Arg-Phe Arg-Phe Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 2348 Phe-Phe Phe-Phe Phe-Phe Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 2349 Tyr-Phe Tyr-Phe Tyr-Phe Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 2350 His-Phe His-Phe His-Phe Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 2351 Pro-Phe Pro-Phe Pro-Phe Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- Met(O)-Thr-Lys-Pro-Gly- 2352 Lys-Phe Lys-Phe Lys-Phe Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 2353 Phe Phe Phe Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 2354 Arg-Phe Arg-Phe Arg-Phe Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 2355 Phe-Phe Phe-Phe Phe-Phe Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 2356 Tyr-Phe Tyr-Phe Tyr-Phe Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 2357 His-Phe His-Phe His-Phe Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 2358 Pro-Phe Pro-Phe Pro-Phe Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- Met(O)-Thr-Lys-Pro-Asp- 2359 Lys-Phe Lys-Phe Lys-Phe Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 2360 Phe Phe Phe Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 2361 Arg-Phe Arg-Phe Arg-Phe Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 2362 Phe-Phe Phe-Phe Phe-Phe Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 2363 Tyr-Phe Tyr-Phe Tyr-Phe Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 2364 His-Phe His-Phe His-Phe Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 2365 Pro-Phe Pro-Phe Pro-Phe Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- Met(O)-Thr-Lys-Pro-Trp- 2366 Lys-Phe Lys-Phe Lys-Phe Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 2367 Phe Phe Phe Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 2368 Arg-Phe Arg-Phe Arg-Phe Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 2369 Phe-Phe Phe-Phe Phe-Phe Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 2370 Tyr-Phe Tyr-Phe Tyr-Phe Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 2371 His-Phe His-Phe His-Phe Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 2372 Pro-Phe Pro-Phe Pro-Phe Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- Met(O)-Thr-Lys-Pro-Gln- 2373 Lys-Phe Lys-Phe Lys-Phe Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 2374 Phe Phe Phe Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 2375 Arg-Phe Arg-Phe Arg-Phe Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 2376 Phe-Phe Phe-Phe Phe-Phe Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 2377 Tyr-Phe Tyr-Phe Tyr-Phe Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 2378 His-Phe His-Phe His-Phe Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 2379 Pro-Phe Pro-Phe Pro-Phe Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- Met(O)-Thr-Lys-Pro-Asn- 2380 Lys-Phe Lys-Phe Lys-Phe Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 2381 Phe Phe Phe Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 2382 Arg-Phe Arg-Phe Arg-Phe Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 2383 Phe-Phe Phe-Phe Phe-Phe Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 2384 Tyr-Phe Tyr-Phe Tyr-Phe Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 2385 His-Phe His-Phe His-Phe Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 2386 Pro-Phe Pro-Phe Pro-Phe Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- Met(O)-Thr-Lys-Pro-Tyr- 2387 Lys-Phe Lys-Phe Lys-Phe Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 2388 Phe Phe Phe Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 2389 Arg-Phe Arg-Phe Arg-Phe Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 2390 Phe-Phe Phe-Phe Phe-Phe Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 2391 Tyr-Phe Tyr-Phe Tyr-Phe Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 2392 His-Phe His-Phe His-Phe Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 2393 Pro-Phe Pro-Phe Pro-Phe Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- Met(O)-Thr-Lys-Pro-Arg- 2394 Lys-Phe Lys-Phe Lys-Phe Thr-Thr-Lys-Pro-Phe Thr-Thr-Lys-Pro-Phe Thr-Thr-Lys-Pro-Phe 2395 Thr-Thr-Lys-Pro-Arg-Phe Thr-Thr-Lys-Pro-Arg-Phe Thr-Thr-Lys-Pro-Arg-Phe 2396 Thr-Thr-Lys-Pro-Phe-Phe Thr-Thr-Lys-Pro-Phe-Phe Thr-Thr-Lys-Pro-Phe-Phe 2397 Thr-Thr-Lys-Pro-Tyr-Phe Thr-Thr-Lys-Pro-Tyr-Phe Thr-Thr-Lys-Pro-Tyr-Phe 2398 Thr-Thr-Lys-Pro-Gly-Phe Thr-Thr-Lys-Pro-Gly-Phe Thr-Thr-Lys-Pro-Gly-Phe 2399 Thr-Thr-Lys-Pro-His-Phe Thr-Thr-Lys-Pro-His-Phe Thr-Thr-Lys-Pro-His-Phe 2400 Thr-Thr-Lys-Pro-Lys-Phe Thr-Thr-Lys-Pro-Lys-Phe Thr-Thr-Lys-Pro-Lys-Phe 2401 Thr-Thr-Lys-Pro-Gly-Phe Thr-Thr-Lys-Pro-Gly-Phe Thr-Thr-Lys-Pro-Gly-Phe 2402 Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Arg- Thr-Thr-Lys-Pro-Gly-Arg- 2403 Arg-Phe Phe Phe Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Phe- Thr-Thr-Lys-Pro-Gly-Phe- 2404 Phe-Phe Phe Phe Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Tyr- Thr-Thr-Lys-Pro-Gly-Tyr- 2405 Tyr-Phe Phe Phe Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- Thr-Thr-Lys-Pro-Gly-His- 2406 Phe Phe Phe Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- Thr-Thr-Lys-Pro-Gly-Pro- 2407 Phe Phe Phe Thr-Thr-Lys-Pro-Gly- Thr-Thr-Lys-Pro-Gly-Lys- Thr-Thr-Lys-Pro-Gly-Lys- 2408 Lys-Phe Phe Phe Thr-Thr-Lys-Pro-Asp-Phe Thr-Thr-Lys-Pro-Asp-Phe Thr-Thr-Lys-Pro-Asp-Phe 2409 Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Arg- Thr-Thr-Lys-Pro-Asp- 2410 Arg-Phe Phe Arg-Phe Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Phe- Thr-Thr-Lys-Pro-Asp- 2411 Phe-Phe Phe Phe-Phe Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Tyr- Thr-Thr-Lys-Pro-Asp-Tyr- 2412 Tyr-Phe Phe Phe Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-His- Thr-Thr-Lys-Pro-Asp-His-

2413 His-Phe Phe Phe Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Pro- Thr-Thr-Lys-Pro-Asp-Pro- 2414 Pro-Phe Phe Phe Thr-Thr-Lys-Pro-Asp- Thr-Thr-Lys-Pro-Asp-Lys- Thr-Thr-Lys-Pro-Asp- 2415 Lys-Phe Phe Lys-Phe Thr-Thr-Lys-Pro-Trp-Phe Thr-Thr-Lys-Pro-Trp-Phe Thr-Thr-Lys-Pro-Trp-Phe 2416 Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Arg- Thr-Thr-Lys-Pro-Trp-Arg- 2417 Arg-Phe Phe Phe Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Phe- Thr-Thr-Lys-Pro-Trp-Phe- 2418 Phe-Phe Phe Phe Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- Thr-Thr-Lys-Pro-Trp-Tyr- 2419 Phe Phe Phe Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- Thr-Thr-Lys-Pro-Trp-His- 2420 Phe Phe Phe Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- Thr-Thr-Lys-Pro-Trp-Pro- 2421 Phe Phe Phe Thr-Thr-Lys-Pro-Trp- Thr-Thr-Lys-Pro-Trp-Lys- Thr-Thr-Lys-Pro-Trp-Lys- 2422 Lys-Phe Phe Phe Thr-Thr-Lys-Pro-Gln-Phe Thr-Thr-Lys-Pro-Gln-Phe Thr-Thr-Lys-Pro-Gln-Phe 2423 Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Arg- Thr-Thr-Lys-Pro-Gln-Arg- 2424 Arg-Phe Phe Phe Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Phe- Thr-Thr-Lys-Pro-Gln-Phe- 2425 Phe-Phe Phe Phe Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Tyr- Thr-Thr-Lys-Pro-Gln-Tyr- 2426 Tyr-Phe Phe Phe Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- Thr-Thr-Lys-Pro-Gln-His- 2427 Phe Phe Phe Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- Thr-Thr-Lys-Pro-Gln-Pro- 2428 Phe Phe Phe Thr-Thr-Lys-Pro-Gln- Thr-Thr-Lys-Pro-Gln-Lys- Thr-Thr-Lys-Pro-Gln-Lys- 2429 Lys-Phe Phe Phe Thr-Thr-Lys-Pro-Asn-Phe Thr-Thr-Lys-Pro-Asn-Phe Thr-Thr-Lys-Pro-Asn-Phe 2430 Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Arg- Thr-Thr-Lys-Pro-Asn- 2431 Arg-Phe Phe Arg-Phe Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Phe- Thr-Thr-Lys-Pro-Asn- 2432 Phe-Phe Phe Phe-Phe Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Tyr- Thr-Thr-Lys-Pro-Asn-Tyr- 2433 Tyr-Phe Phe Phe Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-His- Thr-Thr-Lys-Pro-Asn-His- 2434 His-Phe Phe Phe Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Pro- Thr-Thr-Lys-Pro-Asn-Pro- 2435 Pro-Phe Phe Phe Thr-Thr-Lys-Pro-Asn- Thr-Thr-Lys-Pro-Asn-Lys- Thr-Thr-Lys-Pro-Asn- 2436 Lys-Phe Phe Lys-Phe Thr-Thr-Lys-Pro-Tyr-Phe Thr-Thr-Lys-Pro-Tyr-Phe Thr-Thr-Lys-Pro-Tyr-Phe 2437 Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Arg- Thr-Thr-Lys-Pro-Tyr-Arg- 2438 Arg-Phe Phe Phe Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Phe- Thr-Thr-Lys-Pro-Tyr-Phe- 2439 Phe-Phe Phe Phe Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- Thr-Thr-Lys-Pro-Tyr-Tyr- 2440 Phe Phe Phe Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- Thr-Thr-Lys-Pro-Tyr-His- 2441 Phe Phe Phe Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- Thr-Thr-Lys-Pro-Tyr-Pro- 2442 Phe Phe Phe Thr-Thr-Lys-Pro-Tyr- Thr-Thr-Lys-Pro-Tyr-Lys- Thr-Thr-Lys-Pro-Tyr-Lys- 2443 Lys-Phe Phe Phe Thr-Thr-Lys-Pro-Arg-Phe Thr-Thr-Lys-Pro-Arg-Phe Thr-Thr-Lys-Pro-Arg-Phe 2444 Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Arg- Thr-Thr-Lys-Pro-Arg- 2445 Arg-Phe Phe Arg-Phe Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Phe- Thr-Thr-Lys-Pro-Arg-Phe- 2446 Phe-Phe Phe Phe Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Tyr- Thr-Thr-Lys-Pro-Arg-Tyr- 2447 Tyr-Phe Phe Phe Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-His- Thr-Thr-Lys-Pro-Arg-His- 2448 His-Phe Phe Phe Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Pro- Thr-Thr-Lys-Pro-Arg-Pro- 2449 Pro-Phe Phe Phe Thr-Thr-Lys-Pro-Arg- Thr-Thr-Lys-Pro-Arg-Lys- Thr-Thr-Lys-Pro-Arg-Lys- 2450 Lys-Phe Phe Phe Ala-Thr-Lys-Pro-Phe Ala-Thr-Lys-Pro-Phe Ala-Thr-Lys-Pro-Phe 2451 Ala-Thr-Lys-Pro-Arg-Phe Ala-Thr-Lys-Pro-Arg-Phe Ala-Thr-Lys-Pro-Arg-Phe 2452 Ala-Thr-Lys-Pro-Phe-Phe Ala-Thr-Lys-Pro-Phe-Phe Ala-Thr-Lys-Pro-Phe-Phe 2453 Ala-Thr-Lys-Pro-Tyr-Phe Ala-Thr-Lys-Pro-Tyr-Phe Ala-Thr-Lys-Pro-Tyr-Phe 2454 Ala-Thr-Lys-Pro-Gly-Phe Ala-Thr-Lys-Pro-Gly-Phe Ala-Thr-Lys-Pro-Gly-Phe 2455 Ala-Thr-Lys-Pro-His-Phe Ala-Thr-Lys-Pro-His-Phe Ala-Thr-Lys-Pro-His-Phe 2456 Ala-Thr-Lys-Pro-Lys-Phe Ala-Thr-Lys-Pro-Lys-Phe Ala-Thr-Lys-Pro-Lys-Phe 2457 Ala-Thr-Lys-Pro-Gly-Phe Ala-Thr-Lys-Pro-Gly-Phe Ala-Thr-Lys-Pro-Gly-Phe 2458 Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Arg- Ala-Thr-Lys-Pro-Gly-Arg- 2459 Arg-Phe Phe Phe Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Phe- Ala-Thr-Lys-Pro-Gly-Phe- 2460 Phe-Phe Phe Phe Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Tyr- Ala-Thr-Lys-Pro-Gly-Tyr- 2461 Tyr-Phe Phe Phe Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- Ala-Thr-Lys-Pro-Gly-His- 2462 Phe Phe Phe Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- Ala-Thr-Lys-Pro-Gly-Pro- 2463 Phe Phe Phe Ala-Thr-Lys-Pro-Gly- Ala-Thr-Lys-Pro-Gly-Lys- Ala-Thr-Lys-Pro-Gly-Lys- 2464 Lys-Phe Phe Phe Ala-Thr-Lys-Pro-Asp-Phe Ala-Thr-Lys-Pro-Asp-Phe Ala-Thr-Lys-Pro-Asp-Phe 2465 Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Arg- Ala-Thr-Lys-Pro-Asp- 2466 Arg-Phe Phe Arg-Phe Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Phe- Ala-Thr-Lys-Pro-Asp- 2467 Phe-Phe Phe Phe-Phe Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Tyr- Ala-Thr-Lys-Pro-Asp-Tyr- 2468 Tyr-Phe Phe Phe Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-His- Ala-Thr-Lys-Pro-Asp-His- 2469 His-Phe Phe Phe Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Pro- Ala-Thr-Lys-Pro-Asp-Pro- 2470 Pro-Phe Phe Phe Ala-Thr-Lys-Pro-Asp- Ala-Thr-Lys-Pro-Asp-Lys- Ala-Thr-Lys-Pro-Asp- 2471 Lys-Phe Phe Lys-Phe Ala-Thr-Lys-Pro-Trp-Phe Ala-Thr-Lys-Pro-Trp-Phe Ala-Thr-Lys-Pro-Trp-Phe 2472 Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Arg- Ala-Thr-Lys-Pro-Trp-Arg- 2473 Arg-Phe Phe Phe Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Phe- Ala-Thr-Lys-Pro-Trp-Phe- 2474 Phe-Phe Phe Phe Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- Ala-Thr-Lys-Pro-Trp-Tyr- 2475 Phe Phe Phe Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- Ala-Thr-Lys-Pro-Trp-His- 2476 Phe Phe Phe Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- Ala-Thr-Lys-Pro-Trp-Pro- 2477 Phe Phe Phe Ala-Thr-Lys-Pro-Trp- Ala-Thr-Lys-Pro-Trp-Lys- Ala-Thr-Lys-Pro-Trp-Lys- 2478 Lys-Phe Phe Phe Ala-Thr-Lys-Pro-Gln-Phe Ala-Thr-Lys-Pro-Gln-Phe Ala-Thr-Lys-Pro-Gln-Phe 2479 Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Arg- Ala-Thr-Lys-Pro-Gln-Arg- 2480 Arg-Phe Phe Phe Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Phe- Ala-Thr-Lys-Pro-Gln-Phe- 2481 Phe-Phe Phe Phe Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Tyr- Ala-Thr-Lys-Pro-Gln-Tyr-

2482 Tyr-Phe Phe Phe Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- Ala-Thr-Lys-Pro-Gln-His- 2483 Phe Phe Phe Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- Ala-Thr-Lys-Pro-Gln-Pro- 2484 Phe Phe Phe Ala-Thr-Lys-Pro-Gln- Ala-Thr-Lys-Pro-Gln-Lys- Ala-Thr-Lys-Pro-Gln-Lys- 2485 Lys-Phe Phe Phe Ala-Thr-Lys-Pro-Asn-Phe Ala-Thr-Lys-Pro-Asn-Phe Ala-Thr-Lys-Pro-Asn-Phe 2486 Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Arg- Ala-Thr-Lys-Pro-Asn- 2487 Arg-Phe Phe Arg-Phe Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Phe- Ala-Thr-Lys-Pro-Asn- 2488 Phe-Phe Phe Phe-Phe Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Tyr- Ala-Thr-Lys-Pro-Asn-Tyr- 2489 Tyr-Phe Phe Phe Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-His- Ala-Thr-Lys-Pro-Asn-His- 2490 His-Phe Phe Phe Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Pro- Ala-Thr-Lys-Pro-Asn-Pro- 2491 Pro-Phe Phe Phe Ala-Thr-Lys-Pro-Asn- Ala-Thr-Lys-Pro-Asn-Lys- Ala-Thr-Lys-Pro-Asn- 2492 Lys-Phe Phe Lys-Phe Ala-Thr-Lys-Pro-Tyr-Phe Ala-Thr-Lys-Pro-Tyr-Phe Ala-Thr-Lys-Pro-Tyr-Phe 2493 Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Arg- Ala-Thr-Lys-Pro-Tyr-Arg- 2494 Arg-Phe Phe Phe Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Phe- Ala-Thr-Lys-Pro-Tyr-Phe- 2495 Phe-Phe Phe Phe Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- Ala-Thr-Lys-Pro-Tyr-Tyr- 2496 Phe Phe Phe Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- Ala-Thr-Lys-Pro-Tyr-His- 2497 Phe Phe Phe Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- Ala-Thr-Lys-Pro-Tyr-Pro- 2498 Phe Phe Phe Ala-Thr-Lys-Pro-Tyr- Ala-Thr-Lys-Pro-Tyr-Lys- Ala-Thr-Lys-Pro-Tyr-Lys- 2499 Lys-Phe Phe Phe Ala-Thr-Lys-Pro-Arg-Phe Ala-Thr-Lys-Pro-Arg-Phe Ala-Thr-Lys-Pro-Arg-Phe 2500 Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Arg- Ala-Thr-Lys-Pro-Arg- 2501 Arg-Phe Phe Arg-Phe Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Phe- Ala-Thr-Lys-Pro-Arg-Phe- 2502 Phe-Phe Phe Phe Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Tyr- Ala-Thr-Lys-Pro-Arg-Tyr- 2503 Tyr-Phe Phe Phe Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-His- Ala-Thr-Lys-Pro-Arg-His- 2504 His-Phe Phe Phe Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Pro- Ala-Thr-Lys-Pro-Arg-Pro- 2505 Pro-Phe Phe Phe Ala-Thr-Lys-Pro-Arg- Ala-Thr-Lys-Pro-Arg-Lys- Ala-Thr-Lys-Pro-Arg-Lys- 2506 Lys-Phe Phe Phe His-Thr-Lys-Pro-Phe His-Thr-Lys-Pro-Phe His-Thr-Lys-Pro-Phe 2507 His-Thr-Lys-Pro-Arg-Phe His-Thr-Lys-Pro-Arg-Phe His-Thr-Lys-Pro-Arg-Phe 2508 His-Thr-Lys-Pro-Phe-Phe His-Thr-Lys-Pro-Phe-Phe His-Thr-Lys-Pro-Phe-Phe 2509 His-Thr-Lys-Pro-Tyr-Phe His-Thr-Lys-Pro-Tyr-Phe His-Thr-Lys-Pro-Tyr-Phe 2510 His-Thr-Lys-Pro-Gly-Phe His-Thr-Lys-Pro-Gly-Phe His-Thr-Lys-Pro-Gly-Phe 2511 His-Thr-Lys-Pro-His-Phe His-Thr-Lys-Pro-His-Phe His-Thr-Lys-Pro-His-Phe 2512 His-Thr-Lys-Pro-Lys-Phe His-Thr-Lys-Pro-Lys-Phe His-Thr-Lys-Pro-Lys-Phe 2513 His-Thr-Lys-Pro-Gly-Phe His-Thr-Lys-Pro-Gly-Phe His-Thr-Lys-Pro-Gly-Phe 2514 His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Arg- His-Thr-Lys-Pro-Gly-Arg- 2515 Arg-Phe Phe Phe His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Phe- His-Thr-Lys-Pro-Gly-Phe- 2516 Phe-Phe Phe Phe His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- His-Thr-Lys-Pro-Gly-Tyr- 2517 Phe Phe Phe His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- His-Thr-Lys-Pro-Gly-His- 2518 Phe Phe Phe His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- His-Thr-Lys-Pro-Gly-Pro- 2519 Phe Phe Phe His-Thr-Lys-Pro-Gly- His-Thr-Lys-Pro-Gly-Lys- His-Thr-Lys-Pro-Gly-Lys- 2520 Lys-Phe Phe Phe His-Thr-Lys-Pro-Asp-Phe His-Thr-Lys-Pro-Asp-Phe His-Thr-Lys-Pro-Asp-Phe 2521 His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Arg- His-Thr-Lys-Pro-Asp- 2522 Arg-Phe Phe Arg-Phe His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Phe- His-Thr-Lys-Pro-Asp-Phe- 2523 Phe-Phe Phe Phe His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Tyr- His-Thr-Lys-Pro-Asp-Tyr- 2524 Tyr-Phe Phe Phe His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-His- His-Thr-Lys-Pro-Asp-His- 2525 His-Phe Phe Phe His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Pro- His-Thr-Lys-Pro-Asp-Pro- 2526 Pro-Phe Phe Phe His-Thr-Lys-Pro-Asp- His-Thr-Lys-Pro-Asp-Lys- His-Thr-Lys-Pro-Asp-Lys- 2527 Lys-Phe Phe Phe His-Thr-Lys-Pro-Trp-Phe His-Thr-Lys-Pro-Trp-Phe His-Thr-Lys-Pro-Trp-Phe 2528 His-Thr-Lys-Pro-Trp- His-Thr-Lys-Pro-Trp-Arg- His-Thr-Lys-Pro-Trp-Arg- 2529 Arg-Phe Phe Phe His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- His-Thr-Lys-Pro-Trp-Phe- 2530 Phe Phe Phe His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- His-Thr-Lys-Pro-Trp-Tyr- 2531 Phe Phe Phe His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- His-Thr-Lys-Pro-Trp-His- 2532 Phe Phe Phe His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- His-Thr-Lys-Pro-Trp-Pro- 2533 Phe Phe Phe His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- His-Thr-Lys-Pro-Trp-Lys- 2534 Phe Phe Phe His-Thr-Lys-Pro-Gln-Phe His-Thr-Lys-Pro-Gln-Phe His-Thr-Lys-Pro-Gln-Phe 2535 His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Arg- His-Thr-Lys-Pro-Gln-Arg- 2536 Arg-Phe Phe Phe His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Phe- His-Thr-Lys-Pro-Gln-Phe- 2537 Phe-Phe Phe Phe His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- His-Thr-Lys-Pro-Gln-Tyr- 2538 Phe Phe Phe His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- His-Thr-Lys-Pro-Gln-His- 2539 Phe Phe Phe His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- His-Thr-Lys-Pro-Gln-Pro- 2540 Phe Phe Phe His-Thr-Lys-Pro-Gln- His-Thr-Lys-Pro-Gln-Lys- His-Thr-Lys-Pro-Gln-Lys- 2541 Lys-Phe Phe Phe His-Thr-Lys-Pro-Asn-Phe His-Thr-Lys-Pro-Asn-Phe His-Thr-Lys-Pro-Asn-Phe 2542 His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Arg- His-Thr-Lys-Pro-Asn- 2543 Arg-Phe Phe Arg-Phe His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Phe- His-Thr-Lys-Pro-Asn-Phe- 2544 Phe-Phe Phe Phe His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Tyr- His-Thr-Lys-Pro-Asn-Tyr- 2545 Tyr-Phe Phe Phe His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-His- His-Thr-Lys-Pro-Asn-His- 2546 His-Phe Phe Phe His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Pro- His-Thr-Lys-Pro-Asn-Pro- 2547 Pro-Phe Phe Phe His-Thr-Lys-Pro-Asn- His-Thr-Lys-Pro-Asn-Lys- His-Thr-Lys-Pro-Asn-Lys- 2548 Lys-Phe Phe Phe His-Thr-Lys-Pro-Tyr-Phe His-Thr-Lys-Pro-Tyr-Phe His-Thr-Lys-Pro-Tyr-Phe 2549 His-Thr-Lys-Pro-Tyr- His-Thr-Lys-Pro-Tyr-Arg- His-Thr-Lys-Pro-Tyr-Arg- 2550 Arg-Phe Phe Phe

His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- His-Thr-Lys-Pro-Tyr-Phe- 2551 Phe Phe Phe His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- His-Thr-Lys-Pro-Tyr-Tyr- 2552 Phe Phe Phe His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- His-Thr-Lys-Pro-Tyr-His- 2553 Phe Phe Phe His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- His-Thr-Lys-Pro-Tyr-Pro- 2554 Phe Phe Phe His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- His-Thr-Lys-Pro-Tyr-Lys- 2555 Phe Phe Phe His-Thr-Lys-Pro-Arg-Phe His-Thr-Lys-Pro-Arg-Phe His-Thr-Lys-Pro-Arg-Phe 2556 His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Arg- His-Thr-Lys-Pro-Arg-Arg- 2557 Arg-Phe Phe Phe His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Phe- His-Thr-Lys-Pro-Arg-Phe- 2558 Phe-Phe Phe Phe His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Tyr- His-Thr-Lys-Pro-Arg-Tyr- 2559 Tyr-Phe Phe Phe His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- His-Thr-Lys-Pro-Arg-His- 2560 Phe Phe Phe His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- His-Thr-Lys-Pro-Arg-Pro- 2561 Phe Phe Phe His-Thr-Lys-Pro-Arg- His-Thr-Lys-Pro-Arg-Lys- His-Thr-Lys-Pro-Arg-Lys- 2562 Lys-Phe Phe Phe Lys-Thr-Lys-Pro-Phe Lys-Thr-Lys-Pro-Phe Lys-Thr-Lys-Pro-Phe 2563 Lys-Thr-Lys-Pro-Arg-Phe Lys-Thr-Lys-Pro-Arg-Phe Lys-Thr-Lys-Pro-Arg-Phe 2564 Lys-Thr-Lys-Pro-Phe-Phe Lys-Thr-Lys-Pro-Phe-Phe Lys-Thr-Lys-Pro-Phe-Phe 2565 Lys-Thr-Lys-Pro-Tyr-Phe Lys-Thr-Lys-Pro-Tyr-Phe Lys-Thr-Lys-Pro-Tyr-Phe 2566 Lys-Thr-Lys-Pro-Gly-Phe Lys-Thr-Lys-Pro-Gly-Phe Lys-Thr-Lys-Pro-Gly-Phe 2567 Lys-Thr-Lys-Pro-His-Phe Lys-Thr-Lys-Pro-His-Phe Lys-Thr-Lys-Pro-His-Phe 2568 Lys-Thr-Lys-Pro-Lys-Phe Lys-Thr-Lys-Pro-Lys-Phe Lys-Thr-Lys-Pro-Lys-Phe 2569 Lys-Thr-Lys-Pro-Gly-Phe Lys-Thr-Lys-Pro-Gly-Phe Lys-Thr-Lys-Pro-Gly-Phe 2570 Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Arg- Lys-Thr-Lys-Pro-Gly- 2571 Arg-Phe Phe Arg-Phe Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Phe- Lys-Thr-Lys-Pro-Gly-Phe- 2572 Phe-Phe Phe Phe Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Tyr- Lys-Thr-Lys-Pro-Gly-Tyr- 2573 Tyr-Phe Phe Phe Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-His- Lys-Thr-Lys-Pro-Gly-His- 2574 His-Phe Phe Phe Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Pro- Lys-Thr-Lys-Pro-Gly-Pro- 2575 Pro-Phe Phe Phe Lys-Thr-Lys-Pro-Gly- Lys-Thr-Lys-Pro-Gly-Lys- Lys-Thr-Lys-Pro-Gly-Lys- 2576 Lys-Phe Phe Phe Lys-Thr-Lys-Pro-Asp-Phe Lys-Thr-Lys-Pro-Asp-Phe Lys-Thr-Lys-Pro-Asp-Phe 2577 Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Arg- Lys-Thr-Lys-Pro-Asp- 2578 Arg-Phe Phe Arg-Phe Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Phe- Lys-Thr-Lys-Pro-Asp- 2579 Phe-Phe Phe Phe-Phe Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Tyr- Lys-Thr-Lys-Pro-Asp- 2580 Tyr-Phe Phe Tyr-Phe Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-His- Lys-Thr-Lys-Pro-Asp-His- 2581 His-Phe Phe Phe Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Pro- Lys-Thr-Lys-Pro-Asp-Pro- 2582 Pro-Phe Phe Phe Lys-Thr-Lys-Pro-Asp- Lys-Thr-Lys-Pro-Asp-Lys- Lys-Thr-Lys-Pro-Asp- 2583 Lys-Phe Phe Lys-Phe Lys-Thr-Lys-Pro-Trp-Phe Lys-Thr-Lys-Pro-Trp-Phe Lys-Thr-Lys-Pro-Trp-Phe 2584 Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Arg- Lys-Thr-Lys-Pro-Trp-Arg- 2585 Arg-Phe Phe Phe Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Phe- Lys-Thr-Lys-Pro-Trp-Phe- 2586 Phe-Phe Phe Phe Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Tyr- Lys-Thr-Lys-Pro-Trp-Tyr- 2587 Tyr-Phe Phe Phe Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- Lys-Thr-Lys-Pro-Trp-His- 2588 Phe Phe Phe Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- Lys-Thr-Lys-Pro-Trp-Pro- 2589 Phe Phe Phe Lys-Thr-Lys-Pro-Trp- Lys-Thr-Lys-Pro-Trp-Lys- Lys-Thr-Lys-Pro-Trp-Lys- 2590 Lys-Phe Phe Phe Lys-Thr-Lys-Pro-Gln-Phe Lys-Thr-Lys-Pro-Gln-Phe Lys-Thr-Lys-Pro-Gln-Phe 2591 Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Arg- Lys-Thr-Lys-Pro-Gln- 2592 Arg-Phe Phe Arg-Phe Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Phe- Lys-Thr-Lys-Pro-Gln-Phe- 2593 Phe-Phe Phe Phe Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Tyr- Lys-Thr-Lys-Pro-Gln-Tyr- 2594 Tyr-Phe Phe Phe Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-His- Lys-Thr-Lys-Pro-Gln-His- 2595 His-Phe Phe Phe Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Pro- Lys-Thr-Lys-Pro-Gln-Pro- 2596 Pro-Phe Phe Phe Lys-Thr-Lys-Pro-Gln- Lys-Thr-Lys-Pro-Gln-Lys- Lys-Thr-Lys-Pro-Gln-Lys- 2597 Lys-Phe Phe Phe Lys-Thr-Lys-Pro-Asn-Phe Lys-Thr-Lys-Pro-Asn-Phe Lys-Thr-Lys-Pro-Asn-Phe 2598 Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Arg- Lys-Thr-Lys-Pro-Asn- 2599 Arg-Phe Phe Arg-Phe Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Phe- Lys-Thr-Lys-Pro-Asn- 2600 Phe-Phe Phe Phe-Phe Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Tyr- Lys-Thr-Lys-Pro-Asn- 2601 Tyr-Phe Phe Tyr-Phe Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-His- Lys-Thr-Lys-Pro-Asn-His- 2602 His-Phe Phe Phe Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Pro- Lys-Thr-Lys-Pro-Asn-Pro- 2603 Pro-Phe Phe Phe Lys-Thr-Lys-Pro-Asn- Lys-Thr-Lys-Pro-Asn-Lys- Lys-Thr-Lys-Pro-Asn- 2604 Lys-Phe Phe Lys-Phe Lys-Thr-Lys-Pro-Tyr-Phe Lys-Thr-Lys-Pro-Tyr-Phe Lys-Thr-Lys-Pro-Tyr-Phe 2605 Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Arg- Lys-Thr-Lys-Pro-Tyr-Arg- 2606 Arg-Phe Phe Phe Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Phe- Lys-Thr-Lys-Pro-Tyr-Phe- 2607 Phe-Phe Phe Phe Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- Lys-Thr-Lys-Pro-Tyr-Tyr- 2608 Tyr-Phe Phe Phe Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- Lys-Thr-Lys-Pro-Tyr-His- 2609 Phe Phe Phe Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- Lys-Thr-Lys-Pro-Tyr-Pro- 2610 Phe Phe Phe Lys-Thr-Lys-Pro-Tyr- Lys-Thr-Lys-Pro-Tyr-Lys- Lys-Thr-Lys-Pro-Tyr-Lys- 2611 Lys-Phe Phe Phe Lys-Thr-Lys-Pro-Arg-Phe Lys-Thr-Lys-Pro-Arg-Phe Lys-Thr-Lys-Pro-Arg-Phe 2612 Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Arg- Lys-Thr-Lys-Pro-Arg- 2613 Arg-Phe Phe Arg-Phe Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Phe- Lys-Thr-Lys-Pro-Arg- 2614 Phe-Phe Phe Phe-Phe Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Tyr- Lys-Thr-Lys-Pro-Arg-Tyr- 2615 Tyr-Phe Phe Phe Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-His- Lys-Thr-Lys-Pro-Arg-His- 2616 His-Phe Phe Phe Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Pro- Lys-Thr-Lys-Pro-Arg-Pro- 2617 Pro-Phe Phe Phe Lys-Thr-Lys-Pro-Arg- Lys-Thr-Lys-Pro-Arg-Lys- Lys-Thr-Lys-Pro-Arg- 2618 Lys-Phe Phe Lys-Phe Gly-Thr-Lys-Pro-Phe Gly-Thr-Lys-Pro-Phe Gly-Thr-Lys-Pro-Phe 2619 Gly-Thr-Lys-Pro-Arg-Phe Gly-Thr-Lys-Pro-Arg-Phe Gly-Thr-Lys-Pro-Arg-Phe 2620 Gly-Thr-Lys-Pro-Phe-Phe Gly-Thr-Lys-Pro-Phe-Phe Gly-Thr-Lys-Pro-Phe-Phe 2621

Gly-Thr-Lys-Pro-Tyr-Phe Gly-Thr-Lys-Pro-Tyr-Phe Gly-Thr-Lys-Pro-Tyr-Phe 2622 Gly-Thr-Lys-Pro-Gly-Phe Gly-Thr-Lys-Pro-Gly-Phe Gly-Thr-Lys-Pro-Gly-Phe 2623 Gly-Thr-Lys-Pro-His-Phe Gly-Thr-Lys-Pro-His-Phe Gly-Thr-Lys-Pro-His-Phe 2624 Gly-Thr-Lys-Pro-Lys-Phe Gly-Thr-Lys-Pro-Lys-Phe Gly-Thr-Lys-Pro-Lys-Phe 2625 Gly-Thr-Lys-Pro-Gly-Phe Gly-Thr-Lys-Pro-Gly-Phe Gly-Thr-Lys-Pro-Gly-Phe 2626 Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Arg- Gly-Thr-Lys-Pro-Gly- 2627 Arg-Phe Phe Arg-Phe Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Phe- Gly-Thr-Lys-Pro-Gly-Phe- 2628 Phe-Phe Phe Phe Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Tyr- Gly-Thr-Lys-Pro-Gly-Tyr- 2629 Tyr-Phe Phe Phe Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-His- Gly-Thr-Lys-Pro-Gly-His- 2630 His-Phe Phe Phe Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Pro- Gly-Thr-Lys-Pro-Gly-Pro- 2631 Pro-Phe Phe Phe Gly-Thr-Lys-Pro-Gly- Gly-Thr-Lys-Pro-Gly-Lys- Gly-Thr-Lys-Pro-Gly-Lys- 2632 Lys-Phe Phe Phe Gly-Thr-Lys-Pro-Asp-Phe Gly-Thr-Lys-Pro-Asp-Phe Gly-Thr-Lys-Pro-Asp-Phe 2633 Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Arg- Gly-Thr-Lys-Pro-Asp- 2634 Arg-Phe Phe Arg-Phe Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Phe- Gly-Thr-Lys-Pro-Asp- 2635 Phe-Phe Phe Phe-Phe Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Tyr- Gly-Thr-Lys-Pro-Asp- 2636 Tyr-Phe Phe Tyr-Phe Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-His- Gly-Thr-Lys-Pro-Asp-His- 2637 His-Phe Phe Phe Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Pro- Gly-Thr-Lys-Pro-Asp-Pro- 2638 Pro-Phe Phe Phe Gly-Thr-Lys-Pro-Asp- Gly-Thr-Lys-Pro-Asp-Lys- Gly-Thr-Lys-Pro-Asp- 2639 Lys-Phe Phe Lys-Phe Gly-Thr-Lys-Pro-Trp-Phe Gly-Thr-Lys-Pro-Trp-Phe Gly-Thr-Lys-Pro-Trp-Phe 2640 Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Arg- Gly-Thr-Lys-Pro-Trp-Arg- 2641 Arg-Phe Phe Phe Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Phe- Gly-Thr-Lys-Pro-Trp-Phe- 2642 Phe-Phe Phe Phe Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Tyr- Gly-Thr-Lys-Pro-Trp-Tyr- 2643 Tyr-Phe Phe Phe Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- Gly-Thr-Lys-Pro-Trp-His- 2644 Phe Phe Phe Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- Gly-Thr-Lys-Pro-Trp-Pro- 2645 Phe Phe Phe Gly-Thr-Lys-Pro-Trp- Gly-Thr-Lys-Pro-Trp-Lys- Gly-Thr-Lys-Pro-Trp-Lys- 2646 Lys-Phe Phe Phe Gly-Thr-Lys-Pro-Gln-Phe Gly-Thr-Lys-Pro-Gln-Phe Gly-Thr-Lys-Pro-Gln-Phe 2647 Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Arg- Gly-Thr-Lys-Pro-Gln- 2648 Arg-Phe Phe Arg-Phe Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Phe- Gly-Thr-Lys-Pro-Gln-Phe- 2649 Phe-Phe Phe Phe Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Tyr- Gly-Thr-Lys-Pro-Gln-Tyr- 2650 Tyr-Phe Phe Phe Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-His- Gly-Thr-Lys-Pro-Gln-His- 2651 His-Phe Phe Phe Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Pro- Gly-Thr-Lys-Pro-Gln-Pro- 2652 Pro-Phe Phe Phe Gly-Thr-Lys-Pro-Gln- Gly-Thr-Lys-Pro-Gln-Lys- Gly-Thr-Lys-Pro-Gln-Lys- Lys-Phe Phe Phe 2653 Gly-Thr-Lys-Pro-Asn-Phe Gly-Thr-Lys-Pro-Asn-Phe Gly-Thr-Lys-Pro-Asn-Phe 2654 Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Arg- Gly-Thr-Lys-Pro-Asn- 2655 Arg-Phe Phe Arg-Phe Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Phe- Gly-Thr-Lys-Pro-Asn- 2656 Phe-Phe Phe Phe-Phe Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Tyr- Gly-Thr-Lys-Pro-Asn- 2657 Tyr-Phe Phe Tyr-Phe Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-His- Gly-Thr-Lys-Pro-Asn-His- 2658 His-Phe Phe Phe Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Pro- Gly-Thr-Lys-Pro-Asn-Pro- 2659 Pro-Phe Phe Phe Gly-Thr-Lys-Pro-Asn- Gly-Thr-Lys-Pro-Asn-Lys- Gly-Thr-Lys-Pro-Asn- 2660 Lys-Phe Phe Lys-Phe Gly-Thr-Lys-Pro-Tyr-Phe Gly-Thr-Lys-Pro-Tyr-Phe Gly-Thr-Lys-Pro-Tyr-Phe 2661 Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Arg- Gly-Thr-Lys-Pro-Tyr-Arg- 2662 Arg-Phe Phe Phe Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Phe- Gly-Thr-Lys-Pro-Tyr-Phe- 2663 Phe-Phe Phe Phe Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- Gly-Thr-Lys-Pro-Tyr-Tyr- 2664 Tyr-Phe Phe Phe Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- Gly-Thr-Lys-Pro-Tyr-His- 2665 Phe Phe Phe Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- Gly-Thr-Lys-Pro-Tyr-Pro- 2666 Phe Phe Phe Gly-Thr-Lys-Pro-Tyr- Gly-Thr-Lys-Pro-Tyr-Lys- Gly-Thr-Lys-Pro-Tyr-Lys- 2667 Lys-Phe Phe Phe Gly-Thr-Lys-Pro-Arg-Phe Gly-Thr-Lys-Pro-Arg-Phe Gly-Thr-Lys-Pro-Arg-Phe 2668 Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Arg- Gly-Thr-Lys-Pro-Arg- 2669 Arg-Phe Phe Arg-Phe Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Phe- Gly-Thr-Lys-Pro-Arg- 2670 Phe-Phe Phe Phe-Phe Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Tyr- Gly-Thr-Lys-Pro-Arg-Tyr- 2671 Tyr-Phe Phe Phe Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-His- Gly-Thr-Lys-Pro-Arg-His- 2672 His-Phe Phe Phe Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Pro- Gly-Thr-Lys-Pro-Arg-Pro- 2673 Pro-Phe Phe Phe Gly-Thr-Lys-Pro-Arg- Gly-Thr-Lys-Pro-Arg-Lys- Gly-Thr-Lys-Pro-Arg- 2674 Lys-Phe Phe Lys-Phe

BRIEF DESCRIPTION OF THE DRAWINGS

[0022] FIG. 1 shows a diagram of Arg-Pro-Gly-Pro (SEQ ID NO: 2676) tetrapeptide synthesis;

[0023] FIG. 2 shows a diagram of Pro-Arg-Pro-Gly-Pro (SEQ ID NO: 2675) pentapeptide synthesis;

[0024] FIG. 3 shows a diagram of Pro-Gly-Pro (SEQ ID NO: 2677) tripeptide synthesis;

[0025] FIG. 4 shows a diagram of Thr-Lys-Pro-Arg-Pro-Phe (SEQ ID NO: 7) hexapeptide synthesis;

[0026] FIG. 5 shows a diagram of Thr-Lys-Pro-Arg-Pro (SEQ ID NO: 6) pentapeptide synthesis;

[0027] FIG. 6 shows a diagram of Thr-Lys (SEQ ID NO: 2678) dipeptide synthesis;

[0028] FIG. 7 shows a diagram of Thr-Lys-Pro-Phe (SEQ ID NO: 2679) tetrapeptide synthesis;

BEST EXAMPLE OF THE INVENTION

[0029] The following are the examples illustrating the invention.

[0030] Synthesis of peptides with the general formula A-Thr-Lys-Pro-B-C-D-X was performed by methods of peptide chemistry in solution using L-amino acids. Peptide synthesis was carried out by stepwise elongation of the peptide chain, as well as fragment condensation using mixed anhydride method, carbodiimide method with the addition of 1-hydroxybenzotriazole as an auxiliary nucleophile, activated ester method, and mixed anhydride method. All intermediate and final products were isolated and characterized. Evaporation of solutions was conducted using vacuum evaporator at 40.degree. C. Melting points, determined with Boethius apparatus, are given without correction. Identity of the obtained compounds was tested by TLC on Silufol silica gel-coated plates (Czech Republic). Substances were detected by UV light using ninhydrin, Barton's reagent, Pauly reagent, Reindel-Hoppe reagent, and o-tolidine in chlorine environment. Specific rotation was determined by AI-EPO polarimeter. Peptide homogeneity was tested by high performance liquid chromatography (HPLC), and peptide structure was confirmed by mass spectrometric methods. All solvents were correspondingly absolutized. Melting points were not corrected.

[0031] Peptides were also obtained by genetic engineering techniques using host cells engineered by known laboratory strains of E. coli, transformed with known commercially available plasmids containing nucleic acid encoding the target peptide.

[0032] The examples describe peptide synthesis.

Example 1. Synthesis of Arg-Pro-Gly-Pro Tetrapeptide

[0033] Synthesis of the tetrapeptide was performed according to the diagram shown in FIG. 1.

[0034] In synthesis, mixed anhydride method, azide method and carbodiimide method were used. Derivatives of L-amino acids were used for synthesis. Evaporation of solutions was conducted using rotor evaporator at 40.degree. C. Melting points, determined with Boethius apparatus, are given without correction. Identity of the obtained compounds was tested by TLC on Silufol silica gel-coated plates (Czech Republic). Substances were detected by spraying the plate with a solution of ninhydrin and (or) o-tolidine. Substances were detected by spraying the plate with a solution of ninhydrin and (or) o-tolidine. Chromatographic mobility (Rf) values in the following solvent systems are provided: acetone:benzene:acetic acid (50:100:1)--(1); chloroform:methanol (9:1)--(2); hexane:acetone (3:2)--(3); butanol:acetic acid:water (4:1:1)--(4); butanol:acetic acid:pyridine:water (30:6:20:24)--(5); chloroform:methanol:ammonia (6:4:1)--(6); benzene:ethanol (8:2)--(7); Ethyl acetate:acetone:50% acetic acid:water (2:1:1)--(8); chloroform:methanol (14:1)--(9); chloroform:methanol:ammonia (8:1.75:0.25)--(10); chloroform:methanol:ammonia (6.5:3.0:0.5)--(11).

[0035] Specific rotation was determined by AI-EPO polarimeter.

[0036] Elemental analysis using Carlo-Erba model 1106 analyzer.

[0037] I. Boc-Pro-Gly-OEt.

[0038] 8.3 g (3.45 mmol) of Boc-Pro-OH were dissolved in 50 ml of CH.sub.2Cl.sub.2, cooled down to 5.degree. C.; then, 38.45 mmol (5.38 ml) of TEA were added. The reaction mixture was cooled down to -25/-30.degree. C. At this temperature, 38.45 mmol (4.84 ml) of isobutyl chloroformate were added using a pipette. The reaction mixture temperature was kept in the range of -18/-20.degree. C. for 20 minutes. Simultaneously, a solution of 5.9 g (42.3 mmol) of 1.1-fold excess of HCl.H-Gly-OEt in 75 ml of chloroform, containing 5.92 ml of TEA. The solution was cooled down to -25.degree. C. and, after formation of mixed anhydride in the first flask, its contents were poured to the ether solution right away. The reaction mixture was incubated for 1 hour at -10.degree. C. and then stirred for 12 hours at 4.degree. C. on a magnetic stirrer. The reaction mixture was evaporated, then 250 ml of ethyl acetate were added; then, ethyl acetate solution was washed 3 times with 25 ml of 0.1N HCl, 3 times with 25 ml H.sub.2O, and once with saturated solution of NaCl. The organic layer was dried over MgSO.sub.4, filtered and evaporated. The residue was dried under vacuum over P.sub.2O.sub.5/KOH and paraffin.

[0039] Yield: 10.2 g (30.3 mmol) 78.83%

[0040] Rf--0.5 (7); 0.862 (8)

[0041] Melting point 68-70.degree. C.

[0042] II. Boc-Pro-Gly-N.sub.2H.sub.3.

[0043] 10.2 g of Boc-Pro-Gly-OEt (30.3 mmol) were dissolved in 80 ml of absolute methanol, and 4-fold excess of hydrazine hydrate, viz. 5.88 ml (121.2 mmol), was added. The solution was stirred for 12 hours on a magnetic stirrer at room temperature. The reaction mixture was evaporated, then two times evaporated with ether; then, ether (.about.5 ml) was poured over the residue and left in a refrigerator overnight (for better crystallization, seeding agent was added). The precipitated crystals were filtered, washed with ether using a filter and dried in a desiccator.

[0044] Yield: 6.9 g (20.79 mmol) 68.62%

[0045] Rf--0.284 (7); 0.474 (8); 0.189 (9)

[0046] Melting point 98-100.degree. C.

[0047] III. Boc-Pro-Gly-Pro-OBzl.

[0048] 58.4 mmol (4-fold excess) of hydrogen chloride in ethyl acetate were added to the solution of Boc-Pro-Gly-N.sub.2H.sub.3, containing 4.7 g (14.6 mmol) in 40 ml of DMF, cooled down to -20.degree. C., and, immediately, 1.73 mL (14.6 mmol) of freshly distilled tert-butyl nitrite; then, the reaction mixture was stirred for 30 minutes at -5.degree. C. The reaction mixture was cooled down to -40.degree. C., and solution of 8.2 mL (58.4 mmol) of TEA in 4 mL of DMF, cooled down to -10.degree. C., was added; when the temperature of the reaction mixture had risen to -20.degree. C., 3.7 g (15.3 mmol) of 1.05-fold excess of HCl.H-Pro-OBzl were added to 20 ml of DMF and 2.14 ml of TEA. Then, it was stirred at 4.degree. C. for 24 hours on a magnetic stirrer. The reaction mixture was evaporated, and the residue was dissolved in 200 mL of ethyl acetate and washed 2 times with 20 ml of H.sub.2O, 3 times with 20 ml of 10% sodium KHSO.sub.4, 3 times with 20 ml of H.sub.2O, 3 times with 20 ml of 5% NaHCO3, and 3 times with 20 ml of H.sub.2O. Ethyl acetate solution was dried over MgSO.sub.4. Then it was evaporated, and a small amount of ether (.about.10 mL) was added to the residue. Then, it was left in a refrigerator for crystallization. For better product crystallization, seeding agent was added. The precipitated crystals were filtered and washed with a small amount of ether using a filter. Then, they were dried in a desiccator.

[0049] Yield: 5.358 g (11.65 mmol) 79.92%

[0050] Rf--0.326 (7); 0.947 (8); 0.390 (9)

[0051] Melting point 125-126.degree. C.

[0052] [.alpha.].sub.D.sup.22=-101.18.degree. (c=0.85; CH.sub.3OH).

[0053] Elemental analysis: C, 62.89 (62.73); N, 9.21 (9.14); H, 7.52 (7.24).

[0054] IV. TFA.H-Pro-Gly-Pro-OBzl.

[0055] 5.358 g (11.65 mmol) of Boc-Pro-Gly-Pro-OBzl were dissolved in 29.13 ml of methylene chloride; then, 29.13 mL of TFA were added, incubated for 45 minutes at room temperature, evaporated 2 times with absolute ethanol, 2 times with benzene, 2 times with ether and dissolved in benzene; then, hexane was poured over. Hexane was decanted, and the resulted substance was dried under vacuum in a desiccator over KOH, P.sub.2O.sub.5 and paraffin, while desiccant was changed several times.

[0056] Yield: 4.63 g (9.7 mmol) 98%

[0057] Rf--0.043 (7); 0.247 (8); 0.018 (9).

[0058] V. Boc-Arg(NO2)-Pro-Gly-Pro-OBzl.

[0059] 3.09 g of Boc-Arg (NO.sub.2)--OH (9.7 mmol) were dissolved in 50 mL of THF and 10 ml DMF, 2.07 g (10.67 mmol) of DCC were added, cooled down to 0.degree. C., stirred for 40 minutes; then, a solution of TFA.H-Pro-Gly-Pro-OBzl was added to 50 ml of THF and 4.46 ml (9.7 mmol) of TEA. The reaction mixture was stirred for three days. DCM precipitate was filtered off; the solution was evaporated under vacuum; then, 200 ml of hexane were added to the residue. With this, the desired product was separated as an oil, which was dissolved in 500 mL of ethyl acetate and washed 3 times with 25 ml of 0.1N HCl, three times with 25 ml of H.sub.2O, and once with saturated solution of NaCl. The organic layer was dried over MgSO.sub.4, filtered and evaporated. The residue was dissolved in ethyl acetate and precipitated with dry ether. The precipitate was filtered and dried under vacuum over P.sub.2O.sub.5/KOH and paraffin, while desiccant was changed several times.

[0060] Yield: 4.76 g (7.9 mmol) 85%

[0061] Rf--0.44 (1); 0.8 (11)

[0062] Melting point 108-110.degree. C.

[0063] [.alpha.].sub.D.sup.22=-77.8.degree. (c=0.5; CH.sub.3COOH).

[0064] VI. Boc-Arg-Pro-Gly-Pro.

[0065] 4.76 g (6.5 mmol) of Boc-Arg(NO.sub.2)--Pro-Gly-Pro-OBzl were dissolved in 100 ml of methanol; then 1 ml 1N hydrochloric acid and 4.67 g of catalyst, viz. 10% palladium oxide on neutral aluminum oxide, were added, and hydrogenation in the stream of dry hydrogen at room temperature under 1 atm. was conducted for 6 hours. Then, the catalyst was filtered off and washed on the filter with methanol. Pooled filtrate was evaporated to dryness. The residue was precipitated with ether from the absolute methanol. Then, it was dried under vacuum, while desiccant was changed several times.

[0066] Yield: 4.23 g (5.8 mmol) 89%

[0067] Rf--0.125 (4); 0.57 (6); 0.37 (5)

[0068] Melting point 123-125.degree. C.

[0069] VII. Arg-Pro-Gly-Pro.

[0070] 4.23 g (5.8 mmol) of Boc-Arg-Pro-Gly-Pro-OH were suspended in 10 ml of 2N hydrochloric acid in dioxane and incubated at room temperature for 45 min. Then, dry ether was added, and the precipitate was washed by decantation with dry ether. It was reprecipitated with ether from absolute methanol. The resulting precipitate was dissolved in 7.5 ml of 30% ethanol and applied to Amberlyst A-21 (AcO.sup.- form) column for acetate/hydrochloride salt exchange. Peptide was eluted with 200 ml of 30% ethanol, evaporated to dryness under vacuum and precipitated with absolute ether from methanol.

[0071] Yield: 3.69 g (4.93 mmol) 85%

[0072] Rf--0.287 (4); 0.145 (5); 0.338 (14)

[0073] Melting point 120-122.degree. C.

[0074] HPLC results: Column: Supercosil ABZ Plus, size 4.6.times.250 mm; flow rate 1 mL/min; Eluent A:

[0075] NH.sub.4H.sub.2PO.sub.4+H.sub.3PO.sub.4 (50 mM, pH 2.8); eluent B: MeOH

[0076] Gradient: 0-20 min (0-40% B); retention time 21.21 min.

[0077] Rf--0.24 (6)

[0078] Melting point=151.degree. C.

[0079] [.alpha.].sub.D.sup.22=-65.0.degree. (c=0.5 CH.sub.3COOH)

[0080] HPLC results: Column: Zorbax ODS d=4.6 mm; t=35.degree. C.

[0081] Flow rate 1 mL/min; A=50 mM NH.sub.4H.sub.2PO.sub.4 (pH 2.5); B=A+MeOH (1:1); 10-60% B (in 25 min). Retention time 16.5 min.

Example 2. Synthesis of Pro-Arg-Pro-Gly-Pro Pentapeptide

[0082] Peptide synthesis was performed by classical methods of peptide chemistry using natural L-amino acids according to the diagram shown in FIG. 2.

[0083] First, Pro-Gly-Pro tripeptide was produced; then, pentapeptide was obtained by stepwise buildup of the peptide chain from the N-terminus. In synthesis, mixed anhydride method, azide method and carbodiimide method were used.

[0084] Chromatographic mobility (Rf) values in the following solvent systems are provided: butanol: acetic acid: water (4:1:1)--(1); chloroform:methanol:ammonia (6:4:1)--(2); acetone: benzene: acetic acid (50:100:1)--(3); chloroform:methanol (9:1)--(4); hexane:acetone (3:2)--(5); butanol:acetic acid:pyridine:water (30:6:20:24)--(6); chloroform:methanol (14:1)--(7).

[0085] I. Boc-Pro-Gly-OEt.

[0086] 8.3 g of Boc-Pro (38.45 mmol) were dissolved in 50 ml of CH.sub.2Cl.sub.2, cooled down to +5.degree. C., and 38.45 mmol (5.38 ml) of TEA were added. The reaction mixture was cooled down to -25/-30.degree. C. At this temperature, 38.45 mmol (4.84 ml) of isobutyl chloroformate were added using a pipette. The reaction mixture temperature was kept in the range of -18/-20.degree. C. for 20 minutes. Simultaneously, a solution of 5.9 g (42.3 mmol) of 1.1-fold excess of HCl.H-Gly-OEt in 75 ml of chloroform, containing 5.92 ml of TEA. The solution was cooled down to -25.degree. C. and, after formation of mixed anhydride in the first flask, its contents were poured to the ether solution right away. The reaction mixture was incubated for 1 hour at -10.degree. C. and then stirred for 12 hours at 4.degree. C. on a magnetic stirrer. The reaction mixture was evaporated and 250 ml of ethyl acetate were added to it; the ethyl acetate solution was washed 3 times with 25 ml of 0.1N HCl, 3 times with 25 ml H.sub.2O, and once with saturated solution of NaCl. The organic layer was dried over MgSO4, filtered and evaporated. The residue was dried under vacuum over P.sub.2O.sub.5/KOH and paraffin.

[0087] Yield: 10.2 g (30.3 mmol) 78.83%

[0088] Rf--0.5 (3); 0.862 (4).

[0089] II. Boc-Pro-Gly-N.sub.2H.sub.3.

[0090] 10.2 g of Boc-Pro-Gly-OEt (30.3 mmol) were dissolved in 80 ml of absolute methanol, and 4-fold excess of hydrazine hydrate, viz. 5.88 ml (121.2 mmol), was added. The solution was stirred for 12 hours on a magnetic stirrer at room temperature. The reaction mixture was evaporated, then two times evaporated with ether; then, ether (.about.5 ml) was poured over the residue and left in a refrigerator overnight (for better crystallization, seeding agent was added). The precipitated crystals were filtered, washed with ether using a filter and dried in a desiccator.

[0091] Yield: 6.9 g (20.79 mmol) 68.62%

[0092] Melting point 98-100.degree. C.

[0093] Rf--0.284 (3); 0.474 (4); 0.189 (5).

[0094] III. Boc-Pro-Gly-Pro-OBzl.

[0095] 58.4 mmol (4-fold excess) of hydrogen chloride in ethyl acetate were added to the solution of Boc-Pro-Gly-N.sub.2H.sub.3, containing 4.7 g (14.6 mmol) in 40 ml of DMF, cooled down to -20.degree. C., and, immediately, 1.73 mL (14.6 mmol) of freshly distilled tert-butyl nitrite; then, the reaction mixture was stirred for 30 minutes at -5.degree. C. The reaction mixture was cooled down to -40.degree. C., and solution of 8.2 mL (58.4 mmol) of TEA in 4 mL of DMF, cooled down to -10.degree. C., was added; when the temperature of the reaction mixture had risen to -20.degree. C., 3.7 g (15.3 mmol) of 1.05-fold excess of HCl.H-Pro-OBzl were added to 20 ml of DMF and 2.14 ml of TEA. Then, it was stirred at 4.degree. C. for 24 hours on a magnetic stirrer. The reaction mixture was evaporated, and the residue was dissolved in 200 mL of ethyl acetate and washed 2 times with 20 ml of H.sub.2O, 3 times with 20 ml of 10% sodium KHSO.sub.4, 3 times with 20 ml of H.sub.2O, 3 times with 20 ml of 5% NaHCO.sub.3, and 3 times with 3 ml of H.sub.2O. Ethyl acetate solution was dried over MgSO.sub.4. Then it was evaporated, and a small amount of ether HO mL) was added to the residue. Then, it was left in a refrigerator. For better product crystallization, seeding agent was added. The precipitated crystals were filtered and washed with a small amount of ether using a filter. Then, they were dried in a desiccator.

[0096] Yield: 5.358 g (11.65 mmol) 79.92%

[0097] Rf--0.326 (3); 0.947 (4); 0.390 (5)

[0098] Melting point 125-126.degree. C.

[0099] [.alpha.].sub.D.sup.22=-101.2.degree. (c=0.85; CH.sub.3OH)

[0100] Elemental analysis: C, 62.89 (62.73); N, 9.21 (9.14); H, 7.52 (7.24).

[0101] IV. TFA.H-Pro-Gly-Pro-OBzl.

[0102] 5.358 g (11.65 mmol) of Boc-Pro-Gly-Pro-OBzl were dissolved in 29.13 ml of methylene chloride; 29.13 mL of TFA were added, incubated for 45 minutes at room temperature, evaporated 2 times with absolute ethanol, 2 times with benzene, 2 times with ether and dissolved in benzene; then, hexane was poured over. Hexane was decanted, and the resulted substance was dried under vacuum in a desiccator over P.sub.2O.sub.5/KOH and paraffin.

[0103] Yield: 4.63 g (9.7 mmol) 98%

[0104] Rf--0.043 (3); 0.247 (4); 0.018 (5).

[0105] V. Boc-Arg(NO.sub.2)--Pro-Gly-Pro-OBzl.

[0106] 3.09 g (9.7 mmol) of Boc-Arg (NO.sub.2) were dissolved in 50 ml of THF and 10 ml DMF; then, 2.07 g (10.67 mmol) of DCC were added, cooled down to 0.degree. C. and stirred for 40 minutes; a solution of TFA.H-Pro-Gly-Pro-OBzl was added to 50 ml of THF and 4.46 ml (9.7 mmol) of TEA. The reaction mixture was stirred for three days. DCM precipitate was filtered off; the solution was evaporated under vacuum; then, 200 ml of hexane were added to the residue. With this, the desired product was separated as an oil, which was dissolved in 500 mL of ethyl acetate and washed 3 times with 25 ml of 0.1N HCl, three times with ml of H.sub.2O, and once with saturated solution of NaCl. The organic layer was dried over MgSO4, filtered and evaporated. The residue was dried under vacuum over P.sub.2O.sub.5/KOH and paraffin.

[0107] Yield: 4.76 g (7.9 mmol) 85%

[0108] Rf--0.44 (1); 0.8 (6)

[0109] Melting point 108-110.degree. C.

[0110] VI. TFA-Arg(NO.sub.2)--Pro-Gly-Pro-OBzl.

[0111] 4.76 g (7.9 mmol) of Boc-Arg (NO.sub.2)--Pro-Gly-Pro-OBzl were dissolved in 20 ml of methylene chloride, 20 mL of TFA were added, incubated for 45 minutes at room temperature, evaporated 2 times with absolute ethanol, 2 times with benzene, 2 times with ether, then dissolved in benzene; then, hexane was poured over. Hexane was decanted, and the resulted substance was dried under vacuum in a desiccator over P.sub.2O.sub.5/KOH and paraffin.

[0112] The yield is quantitative.

[0113] Rf--0.16 (1); 0.27 (6).

[0114] VII. Boc-Pro-Arg(NO.sub.2)--Pro-Gly-Pro-OBzl.

[0115] 1.7 g (7.9 mmol) of Boc-Pro were dissolved in 20 mL of THF, and 1.07 g (7.9 mmol) of BT were added, cooled down to 0.degree. C.; 1.8 g of DCC in 50 ml of THF were added. In 40 min, a solution of TFA-Arg(NO.sub.2)--Pro-Gly-Pro-OBzl (7.9 mmol) in 50 mL of THF and 1.1 mL (7.9 mmol) of TEA were added to the reaction mixture. It was stirred for 2 hours at 0.degree. C. and for 2 days at room temperature; then, DCM was filtered off, evaporated under vacuum, dissolved in 500 mL of ethyl acetate and treated similarly to Boc-Pro-Arg(NO.sub.2)--Pro-Gly-Pro-OBzl.

[0116] Yield: 4.07 g (67.8%)

[0117] Rf--0.42 (1); 0.72 (6); 0.31 (7)

[0118] Melting point 147-148.degree. C.

[0119] VIII. Boc-Pro-Arg-Pro-Gly-Pro.

[0120] 4.07 g (6.5 mmol) were dissolved in 100 ml of methanol; 1 ml of 1N hydrochloric acid and 0.85 g of catalyst, viz. 10% palladium oxide on neutral aluminum oxide, were added, and hydrogenation in the stream of dry hydrogen at room temperature under 1 atm. was conducted for 6 hours. Then, the catalyst was filtered off and washed on the filter with methanol. Pooled filtrate was evaporated to dryness. The residue was precipitated with ether from the absolute methanol.

[0121] Yield: 3.02 g (5.8 mmol) 89%

[0122] Rf--0.125 (1), 0.57 (2), 0.37 (6).

[0123] IX. Pro-Arg-Pro-Gly-Pro.

[0124] 3.02 g (5.8 mmol) of Boc-Pro-Arg-Pro-Gly-Pro were suspended in 10 ml of 2N hydrochloric acid in dioxane and were incubated at room temperature for 45 min. Then, dry ether was added, and the precipitate was washed by decantation with dry ether. It was reprecipitated with ether from absolute methanol. The resulting precipitate was dissolved in 7.5 ml of 30% ethanol and applied to Amberlyst A-21 (AcO.sup.--form) column for acetate/hydrochloride salt exchange. Peptide was eluted with 200 ml of 30% ethanol, evaporated to dryness under vacuum and precipitated with absolute ether from methanol.

[0125] Yield: 2.27 g (75%)

[0126] Rf--0.2 (2); 0.1 (6)

[0127] Melting point 180-185.degree. C.

[0128] [.alpha.].sub.D.sup.20=-105.degree. (c=0.4; CH.sub.3COOH).

[0129] Amino acid composition versus arginine: Pro 2.78 (3); Gly 1.1 (1).

[0130] HPLC results: Column: Supercosil ABZ Plus, size 4.6.times.250 mm; flow rate 1 mL/min; Eluent A:

[0131] NH.sub.4H.sub.2PO.sub.4+H.sub.3PO.sub.4 (50 mM, pH 2.8); eluent B: MeOH

[0132] Gradient: 0-20 min (0-40% B); retention time 10.13 min.

Example 3. Synthesis of Pro-Gly-Pro Tripeptide

[0133] The synthesis of Pro-Gly-Pro tripeptide was carried out according to the diagram shown in FIG. 3.

[0134] Synthesis of Pro-Gly-Pro tripeptide was carried out using modern protecting groups and methods of peptide bond formation in solution. Mixed anhydride method with PivCl was used for peptide bond formation. tert-butyloxycarbonyl protection (Boc) was used for protection of amino groups, and benzyl ester (OBzl) was recruited for protection of carboxyl group. Stepwise approach to peptide chain elongation was used.

[0135] Derivatives of L-amino acids were used for synthesis. Evaporation of solutions was conducted using vacuum evaporator at 40.degree. C. Melting points, determined with Boethius apparatus, are given without correction.

[0136] Identity of the obtained compounds was tested by TLC on Silufol silica gel-coated plates (Czech Republic). Substances were detected by spraying the plate with a solution of ninhydrin and (or) o-tolidine. Chromatographic mobility (Rf) values in the following solvent systems are provided: (ethyl acetate:acetone:50% acetic acid:water (2:1:1); benzene:ethanol (8:2); chloroform:methanol:ammonia (6:4:1); chloroform:methanol:acetic acid (42:7:1); acetone:benzene:acetic acid (50:100:1); chloroform:methanol (9:1); hexane:acetone (3:2); butanol:acetic acid:water (4:1:1); butanol:acetic acid:pyridine:water (30:6:20:24); hexane:ethyl acetate (4:1); chloroform:methanol:ammonia (8:1.75:0.25); (isopropanol:formic acid:water) (20:5:1); (chloroform:methanol:ammonia) (7:2.5:0.5); methanol. Specific rotation was determined by AI-EPO polarimeter). Elemental analysis using Carlo-Erba model 1106 analyzer.

[0137] I. Production of Boc-Pro-Gly-OH.

[0138] 1. 10.75 g (50 mmol) of Boc-Pro were dissolved in 150 ml of acetonitrile, cooled down to -5.degree. C.; then, 7.7 ml (50 mmol) of triethylamine (TEA) were added to the solution, and it was cooled down to -20.degree. C., while stirring on a magnetic stirrer. 6.8 ml (55 mmol) of pivaloyl chloride (PivCl) were added to the cooled solution, stirred on a magnetic stirrer for 20 minutes at -10.degree. C. and then cooled down to -30.degree. C.; then, precooled solution of Gly was added. Simultaneously, Gly solution was prepared

[0139] 2. 4.5 g of Gly (60 mmol, 1.2-fold excess) were dissolved in 35 ml of water and 60 ml of acetonitrile, 8.4 ml (60 mmol) of triethylamine were added. The mixture was cooled down to -10.degree. C. and added to the solution in the first flask after 20 minutes. The reaction mixture was incubated for 1 hour at -10.degree. C. and stirred for 2 hours at 18-20.degree. C. on a magnetic stirrer. The reaction mixture was evaporated on a rotary evaporator. About 50 mL of water were added to the residue. The aqueous solution was acidified with a 3-fold excess of NaHSO.sub.4 (24.84 g) to pH=3 and extracted 5 times with 100 ml of ethyl acetate. Pooled ethyl acetate solution was washed with H.sub.2O (50 mL), 10% solution of KHSO.sub.4 (50 mL), H.sub.2O (50 mL), and saturated NaCl (50 mL). Ethyl acetate solution was dried over MgSO4. Dried ethyl acetate was filtered and evaporated. Dry ether was added to the residue. Upon the addition of ether to the flask, it precipitated the product, which was filtered and washed with dry ether using a filter. The resulted substance was dried under vacuum in a desiccator over KOH, P2O5 and paraffin, while desiccant was changed several times.

[0140] Product M.W. 272.3

[0141] Yield: 5.97 g (21.74 mmol); (43.5%)

[0142] Melting point 70.degree. C.

[0143] Rf--0.863 (acetone-benzene-acetic acid) (50:100:1);

[0144] 0.746 (benzene-ethanol) (8:2); 0.903 (chloroform:methanol) (9:1);

[0145] 0.847 (Ethyl acetate:acetone:50% acetic acid:water) (2:1:1).

[0146] II. Production of Boc-Pro-Gly-Pro-OBzl.

[0147] 1. 5.97 g (21.74 mmol) of Boc-Pro-Gly-OH were dissolved in 100 ml of acetonitrile, cooled down to -5.degree. C.; then, 1.1-fold excess (3.35 ml, 23.9 mmol) of triethylamine (TEA) was added to the solution, and it was cooled down to -20.degree. C., while stirring on a magnetic stirrer. 1.1-fold excess (2.34 ml, 23.9 mmol) of pivaloyl chloride (PivCl) was added to the cooled solution, stirred on a magnetic stirrer for 20 minutes at -10.degree. C. and then cooled down to -30.degree. C.; then, precooled solution of HCl.Pro-OBzl was added.

[0148] Simultaneously, HCl.Pro-OBzl was prepared.

[0149] 2. 6.3 g of HCl.Pro-OBzl (26.1 mmol, 1.2 excess) were dissolved in 50 ml of acetonitrile, 4.0 ml (28.71 mmol; 1.1-fold excess) of triethylamine were added. The mixture was cooled down to -10.degree. C. and added to the solution in the first flask after 20 minutes. The reaction mixture was incubated for 1 hour at -10.degree. C. and stirred for 2 hours at 18-20.degree. C. on a magnetic stirrer. The reaction mixture was evaporated. 300 ml of ethyl acetate were added to the evaporated residue. Ethyl acetate solution was washed with H.sub.2O (3 times with 25 mL), 10% solution KHSO.sub.4(3 times with 25 ml) H.sub.2O (3 times with 25 ml), 5% NaHCO.sub.3(3 times with 25 ml) H.sub.2O (3 times 25 mL), and saturated solution of NaCl (once with 25 mL). Ethyl acetate solution was dried over MgSO.sub.4. Dried ethyl acetate was filtered and evaporated. About 100 ml of dry ether were added to the residue. Upon the addition of ether to the flask, it precipitated the product, which was filtered and washed with dry ether using a filter. The resulted substance was dried under vacuum in a desiccator over KOH, P.sub.2O.sub.5 and paraffin, while desiccant was changed several times.

[0150] Product M.W. 459.82

[0151] Yield: 8.12 g (17.66 mmol); (81.23%)

[0152] Melting point 125-126.degree. C.

[0153] Rf--0.326 (acetone:benzene:acetic acid) (50:100:1)

[0154] 0.390 (hexane: acetone) (3:2)

[0155] 0.947 (chloroform:methanol) (9:1)

[0156] 0.716 (methanol)

[0157] 0.620 (benzene: ethanol) (8:2)

[0158] III. Production of Boc-Pro-Gly-Pro-OH.

[0159] 8 g (17.4 mmol) of Boc-Pro-Gly-Pro-OBzl were dissolved in 100 ml of methanol, 0.5 ml of CH.sub.3COOH and palladium black were added, while stirring on a magnetic stirrer, and hydrogen was passed through for 2 hours. The solution was filtered, evaporated, evaporated 3 times with benzene and 2 times with ethyl acetate. Then, it was precipitated with ether hexane from acetone, and the precipitate formed in the flask was dried in a desiccator over P.sub.2O.sub.5/KOH and paraffin.

[0160] Product M.W. 369.39

[0161] Yield: 6.3 g (17.05 mmol) 98%

[0162] Melting point 99-100.degree. C.

[0163] Rf: 0.560 (chloroform-methanol) (9:1)

[0164] 0.812 (chloroform-methanol-acetic acid) (42:7:1)

[0165] 0.187 (acetone:benzene:acetic acid) (50:100:1)

[0166] 0.164 (hexane:acetone) (3:2)

[0167] IV. Production of Pro-Gly-Pro.

[0168] 40.6 ml of methylene chloride and 40.6 ml of TFA were added to 6.0 g (16.24 mmol) of Boc-Pro-Gly-Pro-OH and incubated for 45 minutes at room temperature; after removal of the protecting group, the solution was evaporated 2 times with absolute methanol, 2 times with benzene and 2 times with ether. It was precipitated with ether from acetone. The residue was dried under vacuum over P.sub.2O.sub.5, KOH and paraffin. The dried product was reprecipitated with dry diethyl ether from absolute MeOH.

[0169] Product M.W. 381.39

[0170] Yield: 5.6 g (14.72 mmol) (90.62%)

[0171] The resulting precipitate of TFA.Pro-Gly-Pro-OH was dissolved in 10 ml of 30% ethanol; then, 25 mL of Amberlyst A-21 (CH.sub.3COO.sup.-) ion-exchange resin was added for exchange of trifluoroacetate to acetate salt and stirred on a magnetic stirrer for 45 minutes; then, it was washed with 150 ml of 30% ethanol, evaporated to dryness under vacuum and precipitated with dry diethyl ether from absolute methanol. The resulting precipitate was filtered off and dried in a desiccator under vacuum over P.sub.2O.sub.5, KOH and paraffin, while desiccant was changed several times.

[0172] Product M.W. 328.34

[0173] Yield: 4.54 g (13.84 mmol) (94%)

[0174] Melting point 143-145.degree. C.

[0175] [.alpha.].sub.D.sup.22=-31.5.degree. (c 1, MeOH)

[0176] Rf: 0.59 (chloroform:methanol:ammonia) (6:4:1)

[0177] 0.52 (chloroform:methanol:ammonia) (4:4.5:1.5)

[0178] 0.524 (ethanol: ammonia) (7:3)

Example 4. Synthesis of Thr-Lys-Pro-Arg-Pro-Phe Hexapeptide

[0179] Synthesis of Thr-Lys-Pro-Arg-Pro-Phe hexapeptide was performed according to the diagram shown in FIG. 4.

[0180] Synthesis of Thr-Lys-Pro-Arg-Pro-Phe hexapeptide was carried out using modern protecting groups and methods of peptide bond formation in solution. TBA salt method, activated ester method, carbodiimide method and mixed anhydride method were used for peptide bond formation. Both stepwise and blockwise approaches were used.

Example 5. Synthesis of Thr-Lys-Pro-Arg-Pro Pentapeptide

[0181] Synthesis of Thr-Lys-Pro-Arg-Pro pentapeptide was performed according to the diagram shown in FIG. 5.

[0182] Synthesis of Thr-Lys-Pro-Arg-Pro pentapeptide was carried out using modern protecting groups and methods of peptide bond formation in solution. TBA salt method, activated ester method and carbodiimide method were used for peptide bond formation. Both stepwise and blockwise approaches were used.

Example 6. Synthesis of Thr-Lys Dipeptide

[0183] Synthesis of Thr-Lys dipeptide was performed according to the diagram shown in FIG. 6. Synthesis of Thr-Lys dipeptide was carried out using modern protecting groups and methods of peptide bond formation in solution. TBA salt method, was used for peptide bond formation. Derivatives of both protected and free L-amino acids were used for synthesis of the peptides described in Examples 7-9. The solvents used in peptide synthesis, were correspondingly absolutized. Peptide homogeneity was tested by high performance liquid chromatography (HPLC) using Millichrome A-02 microcolumn liquid chromatographic system. The synthesized peptides were characterized by mass spectrometry using Bruker mass spectrometer (.RTM.Bruker Daltonik GmbH).

Example 7. Synthesis of Thr-Lys-Pro-Phe Tetrapeptide

[0184] The synthesis of Thr-Lys-Pro-Phe tetrapeptide was carried out according to the diagram shown in FIG. 7.

[0185] Synthesis of Thr-Lys-Pro-Phe tetrapeptide was carried out using modern protecting groups and methods of peptide bond formation in solution. TBA salt method and activated ester method were used for peptide bond formation. Stepwise approach to peptide chain elongation was used. Derivatives of both protected and free L-amino acids were used for synthesis. Evaporation of solutions was conducted using vacuum evaporator at 40.degree. C. Melting points, determined with Boethius apparatus, are given without correction. Identity of the obtained compounds was tested by TLC on Silufol silica gel-coated plates (Czech Republic). Substances were detected by spraying the plate with a solution of ninhydrin and (or) o-tolidine. Chromatographic mobility (Rf) values in the following solvent systems are provided: (butanol:acetic acid:water) (4:1:1); (benzene-ethanol) (8:2); (chloroform:methanol) (9:1); (isopropanol:formic acid:water) (20:5:1); (chloroform-methanol-acetic acid) (42:7:1); (chloroform:methanol:ammonia) (8:1.75:0.25); (acetone-benzene-acetic acid) (50:100:1); (chloroform:methanol:ammonia) (6:4:1); (chloroform:methanol:ammonia) (44.5:1.5); (butanol:acetic acid:pyridine:water) (30:6:20:24).

[0186] I. Production of Z-Lys(Boc)-Pro-OH.

[0187] 13% solution of TBA (98 ml) was added to 46.32 mmol (5.34 g) of Pro and evaporated two times with ethanol, two times with ethanol/benzene mixture, and 2 times with benzene. 300 ml of absolute ethyl acetate were added; the reaction mixture was cooled down to 0.degree. C., and 23.16 mmol (12.66 g) of previously synthesized Z-Lys (Boc)-OPfp were added and stirred on a magnetic stirrer for 1 hour. The reaction mass was evaporated, and 40 ml of water were added to the evaporation residue. The aqueous solution was washed 3 times with 80 ml of ether. After washing with ether, the aqueous solution was acidified with citric acid to pH 3. After acidification, aqueous solution was extracted with ethyl acetate 3 times in 40 ml aliquots. Pooled ethyl acetate after extraction was washed 3 times with 20 ml of water, 3 times with 20 ml of 10% solution of KHSO.sub.4, and 3 times with 20 ml of water. Ethyl acetate solution was dried over MgSO.sub.4. Then, it was filtered and evaporated on a rotary evaporator. The resulted substance was precipitated with hexane from ethyl acetate. Hexane was decanted, and the resulted substance was dried under vacuum in a desiccator over KOH, P.sub.2O.sub.5 and paraffin, repeatedly changing desiccant.

[0188] Yield: 9.68 g (20.26 mmol); (87.51%).

[0189] Melting point 76-77.degree. C.

[0190] Rf--0.705 (butanol:acetic acid:water) (4:1:1);

[0191] 0.560 (benzene-ethanol) (8:2);

[0192] 0.476 (chloroform:methanol) (9:1);

[0193] 0.813 (isopropanol:formic acid:water) (20:5:1);

[0194] 0.297 (acetone-benzene-acetic acid) (50:100:1).

[0195] I. Production of H-Lys(Boc)-Pro-OH.

[0196] 300 ml of absolute methanol, 2 ml of acetic acid, and palladium black were added to 9.68 g (20.26 mmol) of Z-Lys(Boc)-Pro-OH, and hydrogenation was performed in the stream of dry hydrogen at room temperature under 1 atm for 8 hours. Then, the catalyst was filtered off and washed on the filter with methanol. Pooled filtrate was evaporated to dryness. The residue was precipitated with ether from the absolute methanol. Then, it was dried under vacuum, while desiccant was changed several times.

[0197] Yield: 6.38 g (18.58 mmol); (91.87%)

[0198] Melting point 98-99.degree. C.

[0199] Rf--0.110 (chloroform-methanol-acetic acid) (42:7:1);

[0200] 0.166 (butanol:acetic acid:water) (4:1:1);

[0201] 0.235 (chloroform:methanol:ammonia) (8:1.75:0.25);

[0202] 0.494 (isopropanol:formic acid:water) (20:5:1) (2:1:1).

[0203] III. Production of Boc-Thr-Lys-Boc)-Pro-OH.

[0204] 13% solution of TBA (39.4 ml) was added to 18.58 mmol (6.38 g) of Lys (Boc)-Pro-OH and evaporated 2 times with ethanol, 2 times with ethanol/benzene mixture and 2 times with benzene. 250 ml of absolute ethyl acetate were added; the reaction mixture was cooled down to 0.degree. C., and 9.2 mmol (3.74 g) of previously synthesized Boc-Thr-OPfp were added and stirred on a magnetic stirrer for 1 hour. The reaction mass was evaporated, and 40 ml of water were added to the evaporation residue. The aqueous solution was washed 3 times with 80 ml of ether. After washing with ether, the aqueous solution was acidified with 18.58 mmol (3.95 g) of citric acid to pH 3. After acidification, aqueous solution was extracted with ethyl acetate 3 times in 40 ml aliquots. Pooled ethyl acetate after extraction was washed 3 times with 20 ml of water, 3 times with 20 ml of 10% solution of KHSO.sub.4, and 3 times with 20 ml of water. Ethyl acetate solution was dried over MgSO.sub.4.

[0205] Then, it was filtered and evaporated on a rotary evaporator. The resulted substance was precipitated with hexane from ethyl acetate. Hexane was decanted, and the resulted substance was dried under vacuum in a desiccator over KOH, P.sub.2O.sub.5 and paraffin, while desiccant was changed several times.

[0206] Yield: 3.32 g (6.1 mmol); (66.26%) Melting point 105-107.degree. C.

[0207] Rf--0.297 (acetone-benzene-acetic acid) (50:100:1);

[0208] 0.234 (chloroform:methanol) (9:1); 0.560 (benzene-ethanol) (8:2).

[0209] IV. Production of Boc-Thr-Lys(Boc)-Pro-Phe-OH.

[0210] 1. Production of Boc-Thr-Lys(Boc)-Pro-OSu.

[0211] 3.53 mmol (0.38 g) of hydroxysuccinimide were added to 1.66 g (3.05 mmol) of Boc-Thr-Lys(Boc)-Pro in 50 ml of absolute ethyl acetate, and the resulting solution was cooled down to 0.degree. C., while stirring on a magnetic stirrer; then, 0.76 g (3.53 mmol) DCC (dicyclohexylcarbodiimide) were added and stirred on a magnetic stirrer at room temperature for 2 hours. After reaction stopped, the resulting reaction mixture was filtered off and the precipitate was discarded. 200 ml of absolute ethyl acetate were added to the resulting solution. Pooled ethyl acetate was washed 2 times with 20 ml of saturated solution of NaCl, two times with 20 ml of 10% sodium KHSO.sub.4, 2 times with 20 ml of saturated solution of NaCl, 2 times with 20 ml of 5% NaHCO.sub.3, and 2 times with 20 ml of saturated solution of NaCl. Ethyl acetate solution was dried over MgSO.sub.4. Then, it was filtered and evaporated on a rotary evaporator. The resulted substance was precipitated with ether and hexane from ethyl acetate. The precipitate was filtered and dried under vacuum over KOH, P.sub.2O.sub.5 and paraffin, while desiccant was changed several times.

[0212] Yield: 1.52 g (2.37 mmol) 77.74%.

[0213] Rf--0.560 (benzene-ethanol) (8:2); 0.457 (chloroform:methanol) (9:1).

[0214] 2. After preparation, 1.52 g (2.37 mmol) of Boc-Thr-Lys (Boc)-Pro-OSu were dissolved in 25 ml of dimethylformamide and added to the prepared solution, containing 0.392 g (2.37 mmol) of L-Phe in 25 ml of dimethylformamide. The solution was stirred on a magnetic stirrer at room temperature. The reaction mixture was evaporated on a rotary evaporator and precipitated with ether from benzene. The precipitate was filtered and dried under vacuum over P.sub.2O.sub.5/KOH and paraffin, while desiccant was changed several times.

[0215] Yield: 1.03 g (1.64 mmol) 69.0%.

[0216] Rf--0.063 (isopropanol:formic acid:water) (20:5:1) (2:1:1).

[0217] 0.745 (chloroform:methanol:ammonia) (8:1.75:0.25);

[0218] V. Production of H-Thr-Lys-Pro-Phe-OH.

[0219] 1.03 g (1.64 mmol) of Boc-Thr-Lys (Boc)-Pro-Phe-OH were added to 8.2 mL of methylene chloride and 8.2 ml of TFA, then the mixture was incubated for 45 minutes at room temperature, and, after removal of protecting groups, the solution was evaporated 2 times with absolute methanol, 2 times with benzene, and 2 times with ether. It was precipitated with ether from methanol. The residue was dried under vacuum over P.sub.2O.sub.5KOH and paraffin. The resulting precipitate was dissolved in 5 ml of 30% ethanol and applied to Amberlyst A-21 (AcO.sup.--form) column for acetate/hydrochloride salt exchange. Peptide was eluted with 100 ml of 30% ethanol, evaporated to dryness under vacuum and precipitated with absolute ether from absolute methanol. The resulting precipitate was filtered and dried in a desiccator under vacuum over P.sub.2O.sub.5, KOH and paraffin, while desiccant was changed several times.

[0220] Yield: 0.7 g (1.43 mmol) (87%).

[0221] Melting point 129-131.degree. C.

[0222] Rf:--0.201 (butanol:acetic acid:pyridine:water) (30:6:20:24);

[0223] 0.156 (chloroform:methanol:ammonia) (4:4.5:1.5).

[0224] Chromatographic and mass spectrometric analysis of peptide sequences, described in Examples 1-7, is shown in Table 2.

TABLE-US-00002 TABLE 2 Mass spectrometric characteristics Chromatographic Fragmenta- SEQ characteristics tion of the ID Tr, Purity, *[M + molecular No Peptide NO MW min % H].sup.+ ion peak** 1 Thr-Lys- 6 597 8.01 97 598 369(100), Pro-Arg- 272(31), Pro 580(29) 2 Thr-Lys- 7 744 14.8 96 745 516(100) Pro-Arg- 0.263(59), Pro-Phe 327(38) 3 Pro-Arg- 2675 522 9.14 89 523 25(100) Pro-Gly- 0.425(27), Pro 407(11) 4 Thr-Lys- 4 500 5.72 94 501 457(100) Pro-Arg 0.272(55), 484(47), 5 Arg-Pro- 2676 425 6.82 85 426 408(100), Gly-Pro 293(54), 254(24) 6 Pro-Gly- 2677 269 5.42 >98 270 173(100), Pro 155(98), 116(75) 7 Thr-Lys- 5 344 4.15 93 345 230(100), Pro 129(19), 212(16) 8 Thr-Lys 2678 247 1.77 95 248 230(100), 129(78), 84(30) 9 Thr-Lys- 2679 500 5.72 94 501 457(100) Pro-Phe 0.272(55), 484(47) Note. *Molecular peak corresponding to [M + H].sup.+ **Most intense ions formed in the fragmentation of the molecular ion peak at the energy of collisions with helium atoms of 35 eV.

[0225] Table 2 shows the data of high performance liquid chromatography (HPLC) using Millichrome A-02 microcolumn liquid chromatographic system and mass spectrometric characteristics of synthesized peptides obtained using ThermoElectron LCQ Advantage MAX mass spectrometer.

[0226] Developed chromatographic conditions allow to easily obtain chromatographically homogeneous product.

[0227] Chromatographic conditions for analysis of peptides.

[0228] Chromatograph: Milichrom-A02

[0229] Column: Prontosil 120-5C18aq, 2*75 mm

[0230] Eluent A: 0.2M LiClO4+5 mM HClO.sub.4

[0231] eluent B: methanol.

[0232] Table 3 presents gradient shape for separation of the synthesized peptides.

TABLE-US-00003 TABLE 3 Time % B 0 5 16.5 80

[0233] Flow rate: 150 .mu.l/min

[0234] Set of wavelengths: 210, 220, 230, 240 nm

[0235] Mass spectrometry conditions

[0236] Equipment: ThermoElectron LCQ Advantage MAX

[0237] Ion source: electrospray; direct introduction of peptide solution with a concentration of 10 .mu.g/ml in 0.1% acetic acid at a flow rate of 5 .mu.l/min Molecular ion fragmentation at 35 eV by ion collisions (He)

[0238] Source temperature: 250.degree. C.

[0239] Ionization potential 3.5 kV

Example 8. Identification of Pharmacophore Position

[0240] To identify pharmacophore, fragments of the parent peptide Selank were synthesized:

[0241] Thr-Lys; Thr-Lys-Pro; Pro-Gly-Pro; Arg-Pro-Gly-Pro; Pro-Arg-Pro-Gly-Pro; and efficacy tests were conducted in vivo using relevant pre-clinical model (Lordosis test).

[0242] We studied the efficacy of the following group of peptides: Thr-Lys; Thr-Lys-Pro; Pro-Gly-Pro; Arg-Pro-Gly-Pro; Pro-Arg-Pro-Gly-Pro in the dose of 100 .mu.g/rat in relation to sexual behavior of female rats. Sexual behavior was recorded in ovariectomized hormonally stimulated females in direct contact with the sexually active male, or when such a contact was impossible. It was found that Thr-Lys-Pro peptide increased the intensity of proceptive behavior in females from 14.+-.4 to 29.+-.6 acts during monitoring (p=0.028, Wilcoxon test). The effect on the lordosis reaction in females had the same trend (p=0.09): the number of lordoses under the action of Thr-Lys-Pro peptide increased from 0.73.+-.0.12 to 0.97.+-.0.12. These results indicate the intensification of sexual motivation on the background of Thr-Lys-Pro peptide action. The effect is specific and manifested in an adequate behavioral situation. Results of efficacy studies of the following peptides: Thr-Lys; Thr-Lys-Pro; Pro-Gly-Pro; Arg-Pro-Gly-Pro; and Pro-Arg-Pro-Gly-Pro; in the model of lordosis are shown in Table 4

TABLE-US-00004 TABLE 4 Test Number of acts SEQ ID Progesterone, product, of proceptive Percentage Group NO mg/rat .mu.g/rat behavior of lordoses Negative Control 0.5 0 14 .+-. 4 0.73 .+-. 0.12 Thr-Lys 2678 0.5 100 13 .+-. 4 0.70 .+-. 0.02 Thr-Lys-Pro 5 0.5 100 29 .+-. 6 0.97 .+-. 0.12 Pro-Gly-Pro 2677 0.5 100 13 .+-. 5 0.74 .+-. 0.09 Arg-Pro-Gly-Pro 2676 0.5 100 15 .+-. 4 0.69 .+-. 0.14 Pro-Arg-Pro-Gly-Pro 2675 0.5 100 14 .+-. 6 0.73 .+-. 0.14 Positive Control 1.0 0 22 .+-. 11 0.98 .+-. 0.09

[0243] Table 4 proves that Thr-Lys-Pro tripeptide is the pharmacophore; furthermore, the smaller sequence, i.e. Thr-Lys dipeptide, does not function, as results from the Table 4.

Example 9. Pharmacophore Test

[0244] To test the pharmacophore, peptides based on it were synthesized, viz. Thr-Lys-Pro tripeptide, Thr-Lys-Pro-Arg (SEQ ID NO: 4) and Thr-Lys-Pro-Phe (SEQ ID NO: 2679) tetrapeptides, Thr-Lys-Pro-Arg-Pro (SEQ ID NO: 6) pentapeptide, and Thr-Lys-Pro-Arg-Pro-Phe (SEQ ID NO: 7) hexapeptide, corresponding to the general formula A-Thr-Lys-Pro-B-C-D-X, efficacy test were conducted on the in vivo, using relevant pre-clinical models (lordosis test).

[0245] We studied the efficacy of the following group of peptides: Thr-Lys-Pro (SEQ ID NO: 5); Thr-Lys-Pro-Arg (SEQ ID NO: 4); Thr-Lys-Pro-Arg-Pro (SEQ ID NO: 6); and Thr-Lys-Pro-Arg-Pro-Phe (SEQ ID NO: 7); at a dose of 100 .mu.g/rat in relation to sexual behavior of female rats. Sexual behavior was recorded in ovariectomized hormonally stimulated females in direct contact with the sexually active male, or when such a contact was impossible. It was found that peptides from the group, including Thr-Lys-Pro (SEQ ID NO: 5), Thr-Lys-Pro-Arg-Pro (SEQ ID NO: 6), and Thr-Lys-Pro-Arg-Pro-Phe (SEQ ID NO: 7), increased the intensity of proceptive behavior in females from 14.+-.4 to 26.+-.4-36.+-.6 acts during monitoring (p=0.028, Wilcoxon test). At the same time, Thr-Lys-Pro-Arg (SEQ ID NO: 4) and Thr-Lys-Pro-Phe (SEQ ID NO: 2679) do not affect the intensity of proceptive behavior of females and do not increase the number of lordoses, and the basic parameters of Thr-Lys-Pro-Arg (SEQ ID NO: 4) and Thr-Lys-Pro-Phe (SEQ ID NO: 2679) tetrapeptides remain at the level of negative control. The effect on the lordosis reaction in females had the same trend (p=0.09). In the absence of direct contact of partners, peptide action was manifested. The results indicate the intensification of sexual motivation on the background of Thr-Lys-Pro (SEQ ID NO: 5), Thr-Lys-Pro-Arg-Pro (SEQ ID NO: 6), Thr-Lys-Pro-Arg-Pro-Phe (SEQ ID NO: 7) peptide action and lack of sexual motivation effect in Thr-Lys-Pro-Arg (SEQ ID NO: 4) and Thr-Lys-Pro-Phe (SEQ ID NO: 2679) tetrapeptides. The effect is specific and manifested in an adequate behavioral situation. Results of efficacy studies of the following peptides: Thr-Lys-Pro; Thr-Lys-Pro-Arg (SEQ ID NO: 4); Thr-Lys-Pro-Phe (SEQ ID NO: 2679); Thr-Lys-Pro-Arg-Pro (SEQ ID NO: 6); Thr-Lys-Pro-Arg-Pro-Phe (SEQ ID NO: 7); in the model of lordosis are shown in Table 5.

TABLE-US-00005 TABLE 5 Number of Test acts of Progesterone product, proceptive Percentage Group SEQ ID NO mg/rat .mu.g/rat behavior of lordoses Negative Control 0.5 0 14 .+-. 4 0.73 .+-. 0.12 Thr-Lys-Pro 5 0.5 100 28 .+-. 4 0.96 .+-. 0.12 Thr-Lys-Pro-Arg 4 0.5 100 14 .+-. 4 0.72 .+-. 0.02 Thr-Lys-Pro-Phe 2679 0.5 100 13 .+-. 5 0.73 .+-. 0.09 Thr-Lys-Pro-Arg-Pro 6 0.5 100 36 .+-. 6 0.99 .+-. 0.09 Thr-Lys-Pro-Arg-Pro- 7 0.5 100 26 .+-. 4 0.94 .+-. 0.14 Phe Positive Control 1.0 0 22 .+-. 11 0.98 + 0.09

INDUSTRIAL APPLICABILITY

[0246] The invention relates to the field of biochemistry, in particular, to a method for producing peptides exhibiting high activity and capable of stimulating self-healing in the organs where a disturbance occurred. In particular, the invention allows to expand the range of tools for stimulation of sexual function and treatment of sexual dysfunction, while reducing the duration of course therapy and the costs of medications.

Sequence CWU 0 SQTB SEQUENCE LISTING The patent application contains a lengthy "Sequence Listing" section. A copy of the "Sequence Listing" is available in electronic form from the USPTO web site (http://seqdata.uspto.gov/?pageRequest=docDetail&DocID=US20170158735A1). An electronic copy of the "Sequence Listing" will also be available from the USPTO upon request and payment of the fee set forth in 37 CFR 1.19(b)(3).

0 SQTB SEQUENCE LISTING The patent application contains a lengthy "Sequence Listing" section. A copy of the "Sequence Listing" is available in electronic form from the USPTO web site (http://seqdata.uspto.gov/?pageRequest=docDetail&DocID=US20170158735A1). An electronic copy of the "Sequence Listing" will also be available from the USPTO upon request and payment of the fee set forth in 37 CFR 1.19(b)(3).

* * * * *

File A Patent Application

  • Protect your idea -- Don't let someone else file first. Learn more.

  • 3 Easy Steps -- Complete Form, application Review, and File. See our process.

  • Attorney Review -- Have your application reviewed by a Patent Attorney. See what's included.